Zika virus:A review of literature
Zika virus:A review of literature作者机构：Ziaeian HospitalTehran University of Medical Sciences Iranian Research Center for HIV/AIDS(IRCHA)Iranian Institute for Reduction of High-Risk BehaviorsTehran University of Medical Sciences
出 版 物：《Asian Pacific Journal of Tropical Biomedicine》 (亚太热带生物医学杂志（英文版）)
年 卷 期：2016年第6卷第12期
页 面：989-994页
核心收录：
学科分类：0710[理学-生物学] 0831[工学-生物医学工程（可授工学、理学、医学学位）] 1007[医学-药学(可授医学、理学学位)] 100705[医学-微生物与生化药学] 1001[医学-基础医学(可授医学、理学学位)] 100103[医学-病原生物学] 10[医学]
主 题：Zika virus Microcephaly Serologic tests Vaccine Treatment Supportive therapy
摘 要：Zika virus(ZIKV) has two lineages:African and ***-borne flaviviruses are thought to replicate initially in dendritic cells and then spread to lymph nodes and the blood *** for infection through blood transfusion,sexual practices and perinatal transmission *** possible routes of perinatal transmission are during delivery,breastfeeding and by close contact between the mother and her ***,mucocutaneous exposures to the virus by infected blood or monkey bite,organ transplantation or hemodialysis are the other routes of ZIKV *** are two types of ZIKV infection;Zika fever and congenital *** presentation of Zika fever varies from asymptomatic infections to a self-limiting febrile disease with low grade fever,conjunctivitis,maculopapular rash,headache,retro-orbital pain and arthritis/arthralgia with periarticular edema,myalgia,vertigo,vomiting and *** clinical feature could be mistaken for dengue or chikungunya *** is the most important and frequently reported clinical picture of suspected congenital Zika *** tests are needed for diagnosis of ZIKV infection,because there is no known pathognomonic clinical,biochemical or radiological ***-PCR is the most wellliked *** samples are tested by immunoglobulin G ELISA with ZIKV *** are also tested by immunoglobulin M *** is no certified vaccine or therapeutic *** asymptomatic or uncomplicated patients,treatment is not necessary.
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