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FOOD BIOSCIENCE 2023年第3期53卷 1025-1033页

作者： Zarali, Maryam sadeghi, alireza Jafari, Seid Mahdi Ebrahimi, Maryam Mahoonak, alireza sadeghi Gorgan Univ Agr Sci & Nat Resources Dept Food Sci & Technol Gorgan Iran Gorgan Univ Agr Sci & Nat Resources Dept Food Mat & Proc Design Engn Gorgan Iran Golestan Univ Med Sci Food Drug & Nat Prod Hlth Res Ctr Gorgan Iran

In the present study, a layer-by-layer technique was used to prepare alginate-nisin (Alg-N) as coating layer to encapsulate a potential probiotic-protective lactic acid bacteria (LAB) isolate in order to improve its both survival and antibacterial activities in situ. The isolate was identified as Pediococcus acidilactici according to the sequencing results of the PCR products. The mean size of Alg and Alg-N microcapsules was also equal to 762.63 and 501.77 mu m, respectively based on the results of field emission scanning electron microscopy. In accordance with the zeta potential data, the Alg-N surrounding layer was confirmed. Furthermore, the Fourier transform infrared findings revealed the adsorption of nisin on the Alg beads. The antibacterial activity of the produced microcapsule on Staphylococcus aureus (100% inhibition) was significantly (P < 0.05) higher than that of the other foodborne bacteria studied. In addition, enhanced viability of the microencapsulated LAB in simulated gastrointestinal conditions and flavored milk, as well as its improved in situ inhibitory effect on S. aureus were verified.

关键词： Layer-by-layer Alginate-nisin coating Enhanced survival In situ antibacterial

Anisotropy of mechanical properties and crystallographic texture in hot rolled AZ31+XSr sheets

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Journal of Magnesium and Alloys 2019年第3期7卷 466-473页

作者： alireza sadeghi Hossein Mortezapour Javad Samei Mihriban Pekguleryuz David Wilkinson School of Mechanical Engineering College of EngineeringUniversity of TehranTehranIran Department of Materials Science and Engineering McMaster UniversityHamiltonONCanada Department of Mining and Materials Science McGill UniversityMontrealQCCanada

The influences of Sr on the microstructure,texture and mechanical properties including flow and anisotropy behavior of AZ31 alloys are *** containing no,0.4 and 0.8 wt%of strontium were cast and subjected to hot *** indicate that Sr reduces the basal texture intensity(23%in the AZ31+0.8Sr alloy)and homogenizes the distribution of strain in uniaxial ***,Sr increases both the strength coefficient and the strain hardening exponent in all *** the transverse direction,enhancements are more ***,Sr enhances the combination of tensile strength and total elongation;i.e.,toughness,whether tests are performed parallel to the rolling,diagonal or transverse directions,to significant extents.

关键词： AZ31 Hot rolling Mechanical properties Microstructure Strontium Texture

Critical current parameterization of high temperature Superconducting Tapes:A novel approach based on fuzzy logic

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Superconductivity 2023年第1期5卷 17-25页

作者： Nitish Varma Ulchi Suresh alireza sadeghi Mohammad Yazdani-Asrami Propulsion Electrification&Superconductivity GroupJames Watt School of EngineeringUniversity of GlasgowGlasgow G128QQUnited Kingdom

In this study a novel method was presented to parameterize the critical current of Yttrium Barium Copper Oxide(YBCO)tapes based on their width,thickness,magnetothermal operational conditions,and the applied *** this purpose,a fuzzy‐logic‐based model was developed that take tapes structures and their operational conditions as inputs to calculate their critical current,as *** results of critical current parame-terization by fuzzy‐logic‐based model showed that the relative error of the proposed model is less than 3%comparing to experimentally acquired ***,the results of presented model was compared to results of semi‐analytical fitting‐based models and fully‐analytical fitting based *** comparisons showed the better performance in terms of accuracy and error of fuzzy logic model over fitting‐based *** last,the results were also compared with the Artificial Neural Network(ANN)‐based parameterization model and Adaptive Nero‐Fuzzy Interference System(ANFIS)‐based parameterization *** proposed method had 6%to 8%higher accuracy and about 47%to 54%lower root mean squared error.

关键词： Artificial intelligence Critical current parameterization Relative error RMSE Tape width Tape thickness YBCO

Role of nanomaterials in improving the functionality of probiotics; integration of nanotechnology onto micro-structured platforms

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FOOD BIOSCIENCE 2023年第3期53卷 3154-3167页

作者： sadeghi, alireza Ebrahimi, Maryam Kharazmi, Mohammad Saeed Jafari, Seid Mahdi Gorgan Univ Agr Sci & Nat Resources Dept Food Sci & Technol Gorgan Iran Golestan Univ Med Sci Food Drug & Nat Prod Hlth Res Ctr Gorgan Iran Univ Calif Riverside Fac Med Riverside CA 92679 USA Gorgan Univ Agr Sci & Nat Resources Dept Food Mat & Proc Design Engn Gorgan Iran

There is a growing interest in the production of probiotics (PRO) enriched food and pharmaceutical products as personalized nutrition and/or medicines. Due to the limitations associated with PRO such as their survival and targeted delivery in food/gastrointestinal matrices, it is necessary to introduce the next-generation PRO (NGPs). Combined formulation of PRO and nanomaterials (NMs) as a promising progress in nano-biotechnology has interesting potential applications. These NMs as proper carrier or coating agents have pivotal importance in food/drug applications of NGPs. There are several case studies related to the unique and promising capabilities of NMs for targeted delivery, long-term viability and stability of PRO, as well as potent infection control by these essential microorganisms and engineering of the smart constructs with enhanced functionalities using these innovative valuable platforms. Furthermore, surface to volume ratio of the produced constructs and adhesion of the PRO onto the intestinal epithelial mucus can be improved using novel NMs. Although integration of PRO with nanostructured platforms has promising beneficial effects, there are some limitations such as potential inhibitory effect of NMs on metabolic activity of PRO that needs to be considered. Furthermore, potential interactions between NMs and food components, their potential side effects on gut hemostasis, as well as concerns about their toxicity and biosafety are important issues in this context. This review sought to present and discuss the most recent cutting-edge publications associated with capabilities of NMs to improve crucial functionalities of the NGPs for their essential and innovative applications.

关键词： Next -generation probiotics Nanostructured platforms Efficiency Smart constructs Biosafety

Short circuit analysis of a fault-tolerant current-limiting high temperature superconducting transformer in a power system in presence of distributed generations

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Superconductivity 2024年第1期9卷 74-86页

作者： alireza sadeghi Shahin Alipour Bonab Wenjuan Song Mohammad Yazdani-Asrami Propulsion Electrification&Superconductivity GroupAutonomous Systems&Connectivity DivisionJames Watt School of EngineeringUniversity of GlasgowGlasgow G128QQUnited Kingdom

Power transformers are key elements for the safe and reliable delivery of electrical energy generated by renewable energy resources to consumers via transmission ***‐tolerant current‐limiting High Temperature Superconducting(FTCL HTS)transformers are type of superconducting transformers that tolerate fault for seconds and limit the fault current without the threat of burnout or delamination of tapes and deformation of *** this paper,the fault performance of a FTCL HTS transformer in a standard IEEE power system is *** studied transformer is a 50 MVA 132 kV/13.8 kV transformer where both windings are made up of HTS *** understudied power system consists of two microgrids with distributed *** of the power in microgrids is supplied by the upstream grid which is connected to the microgrids through the HTS *** fault scenarios have been considered in this power system,in each one of these scenarios,a fault happens in one of the *** considered fault scenarios have an approximate fault current of 18x to 23x of the rated current in the secondary *** showed that insulated windings in FTCL HTS transformers could substantially reduce the peak temperature of the HTS windings,compared to bare ***,post‐fault loading is imposed on the HTS windings,to observe their performance against the current increase after fault *** this case,for the first scenario of the faults,the FTCL HTS transformer could tolerate 192%of post‐fault overloading,while this number for the second fault scenario is 170%.Finally,the impact of post‐fault loading on the full recovery time was discussed.

关键词： Fault Energy Heat dissipation Heat transfer Insulation Recovery Time Temperature rise

Synthesis and characterization of collagen/PLGA biodegradable skin scaffold fibers

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Regenerative Biomaterials 2017年第5期4卷 309-314页

作者： alireza sadeghi-Avalshahr Samira Nokhasteh Amir Mahdi Molavi Mohammad Khorsand-Ghayeni Meysam Mahdavi-Shahri Materials Research Department Iranian Academic Center for EducationCulture and Research(ACECR)Khorasan Razavi BranchMashhadIran

The aim of this study is to investigate the applicability of poly(lactic-co-glycolic acid)(PLGA)/collagen composite scaffold for skin tissue *** and collagen were dissolved in HFIP as a common solvent and fibrous scaffolds were prepared by electrospinning *** scaffolds were characterized by scanning electron microscopy(SEM),FTIR spectroscopy,mercury porosimetry,tensile strength,biocompatibility assays and *** and cell adhesion were tested for two cell line groups,human dermal fibroblast(HDF)and human keratinocyte(HaCat).SEM images showed appropriate cell adhesion to the scaffold for both cell *** assays indicated that the cell viability of HDF cells increased with time,but the number of HaCat cells decreased after 14 *** ultimate tensile strength was suitable for skin substitute application,but its elongation at break was rather *** successful clinical application of the PLGA/collagen scaffold,some properties especially mechanical strain needs to be improved.

关键词： tissue engineering composite scaffold biocompatibility skin cells

Conduction system disorders and electro-cardiographic findings in COVID-19 deceased patients in 2021,Shiraz,Iran

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World Journal of Cardiology 2022年第12期14卷 617-625页

作者： Mohammad Hossein Nikoo alireza sadeghi alireza Estedlal Reza Fereidooni Niloofar Dehdari Ebrahimi Amirhossein Maktabi Mahtab Kamgar Fatemeh Mehran Omid Mehdibeygi Haleh Esfandiari Mohammadamir Taherinezhad Tayebi Seyed Taghi Heydari Noncommunicable Diseases Research Centre Shiraz University of Medical SciencesShirazIran Student Research Committee Shiraz University of Medical SciencesShirazIran Health Policy Research Center Institute of HealthShiraz University of Medical SciencesShirazIran

BACKGROUND Cardiac conduction disorders and electrocardiographic(ECG)changes may occur as a manifestation of coronavirus disease 2019(COVID-19),especially in severe *** To describe conduction system disorders and their association with other electrocardiographic parameters in patients who died of *** In this cross-sectional study,electrocardiographic and clinical data of 432 patients who expired from COVID-19 between August 1st,2021,and December 1st,2021,in a tertiary hospital were *** Among 432 patients who died from COVID-19,atrioventricular block(AVB)was found in 40(9.3%).Among these 40 patients,28(6.5%)suffered from 1st degree AVB,and 12(2.8%)suffered from complete heart block(CHB).Changes in ST-T wave,compatible with myocardial infarction or localized myocarditis,appeared in 189(59.0%).Findings compatible with myocardial injury,such as fragmented QRS and prolonged QTc,were found in 91 patients(21.1%)and 28 patients(6.5%),*** patients who died of COVID-19,conduction disorder was unrelated to any underlying medical *** QRS,axis deviation,and ST-T changes were significantly related to conduction system disorder in patients who died of COVID-19(P value<0.05).CONCLUSION Conduction system disorders are associated with several other ECG abnormalities,especially those indicative of myocardial ischemia or *** patients(73.14%)who died of COVID-19 demonstrated at least one ECG abnormality *** a COVID-19 patient's ECG gives important information regarding their cardiac health,our findings can help develop a risk stratification method for at-risk COVID-19 patients in future studies.

关键词： COVID-19 Conduction system disorder Electrocardiography Atrioventricular block

Analysis of Linear and Nonlinear Vibrations of Composite Rectangular Sandwich Plates with Lattice Cores

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Computers, Materials & Continua 2025年第1期82卷 223-257页

作者： alireza Moradi alireza Shaterzadeh Faculty of Mechanical Engineering Shahrood University of TechnologyShahroodP.O.Box ***Iran

For the first time,the linear and nonlinear vibrations of composite rectangular sandwich plates with various geometric patterns of lattice core have been analytically examined in this *** plate comprises a lattice core located in the middle and several homogeneous orthotropic layers that are symmetrical relative to *** this purpose,the partial differential equations of motion have been derived based on the first-order shear deformation theory,employing Hamilton’s principle and Von Kármán’s nonlinear displacement-strain ***,the nonlinear partial differential equations of the plate are converted into a time-dependent nonlinear ordinary differential equation(Duffing equation)by applying the Galerkin *** the solution of this equation,the natural frequencies are ***,to calculate the non-linear frequencies of the plate,the non-linear equation of the plate has been solved analytically using the method of multiple ***,the effect of some critical parameters of the system,such as the thickness,height,and different angles of the stiffeners on the linear and nonlinear frequencies,has been analyzed in *** confirmthe solution method,the results of this research have been compared with the reported results in the literature and finite elements in ABAQUS,and a perfect match is *** results reveal that the geometry and configuration of core ribs strongly affect the natural frequencies of the plate.

关键词： Free vibration composite sandwich plate lattice core galerkin method Duffing equation multiple scales method

Ground motion record simulation for structural analysis by consideration of spectral acceleration autocorrelation pattern

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Earthquake Engineering and Engineering Vibration 2014年第2期13卷 195-202页

作者： alireza Azarbakht Mahdi sadeghi Mehdi Mousavi Department of Civil Engineering Faculty of Engineering Arak University

A novel approach is introduced to generate simulated ground motion records by considering spectral acceleration correlations at multiple periods. Most of the current reliable Ground Motion Record(GMR) simulation procedures use a seismological model including source, path and site characteristics. However, the response spectrum of simulated GMR is somewhat different when compared with the response spectrum based on recorded GMRs. More specifi cally, the correlation between the spectral values at multiple periods is a characteristic of a record which is usually different between simulated and recorded GMRs. As this correlation has a signifi cant infl uence on the structural response, it is needed to investigate the consistency of the simulated ground motions with actual records. This issue has been investigated in this study by incorporating an optimization algorithm within the Boore simulation technique. Eight seismological key parameters were optimized in order to achieve approximately the same correlation coeffi cients and spectral acceleration between two sets of real and simulated records. The results show that the acceleration response spectra of the synthetic ground motions also have good agreement with the real recorded response spectra by implementation of the proposed optimized values.

关键词： stochastic method simulation ground motion random vibration site amplifi cation EXSIM program

The Gol-e-Zard Zn-Pb Deposit, Lorestan Province, Iran: a Metamorphosed SEDEX Deposit

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Acta Geologica Sinica(English Edition) 2014年第1期88卷 142-153页

作者： alireza ZARASVANDI Mona SAMETI Martiya sadeghi Fatemeh RASTMANESH Hooshang POURKASEB Department of Geology Faculty of Earth Science Shahid Chamran University Department of Mineral Resources Geological Survey of Sweden

The Gol-e-Zard Zn-Pb deposit is one of several sediment-hosted Zn-Pb deposits found in the central part of the Sanadaj-Sirjan Zone, known as the Isfahan-Malayer belt, western Iran. Mineralization occurs in Upper Triassic to Jurassic phyllites and meta-sandstones. Sphalerite and galena are the most abundant metallic ores, with minor chalcopyrite. Calcite and quartz are the main gangue minerals. Fissure filling, replacement textures and especially mineralized faults, suggest an epigenetic stage in the Gol-e-Zard deposit formation. Geochemical studies of mineralized rocks show high concentrations of Zn, Pb and Cu,（Zn and Pb 〉 10000 ppm and Cu average 3000 ppm）. LREE enrichment（LREE〉HREE, La/Lu average 1.44） and positive Eu anomalies（Eu/Eu＊〉1 average 1.67） indicate reducing conditions during the deposition of deposit. However, some samples do not display negative Ce anomalies, which indicate that localized oxidizing conditions are also present. This study indicates that the Gol-e-Zard deposit formed due to circulating hydrothermal fluids in a marine environment. A SEDEX-type genesis, which is defined by circulating hydrothermal fluids through sediments in a marine environment, and syngenetic precipitation of Zn and Pb sulphides, is suggested for the Gol-e-Zard deposit. Emplacement of some granitoid intrusions such as the Aligudarz granitoid intrusion remobilized mineralizing fluids and metamorphosed the Gol-e-Zard deposit.

关键词： SEDEX REE metamorphosed Sanadaj-Sirjan Zone Iran