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Mapping global research trends: Nutrition associations with nonalcoholic f.tty liver disease - a Scopus bibliometric analysis

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World Journal of.Gastroenterology 2024年第24期30卷 3106-3119页

作者： Muna Shakhshir sa'ed H Zyoud Department of.Nutrition An-Najah National University HospitalNablus 44839Palestine Department of.Public Health College of Medicine and Health SciencesAn-Najah National UniversityNablus 44839Palestine Department of.Clinical and Community Pharmacy College of Medicine and Health SciencesAn-Najah National UniversityNablus 44839Palestine Poison Control and Drug Inf.rmation Center College of Medicine and Health SciencesAn-Najah National UniversityNablus 44839Palestine Clinical Research Center An-Najah National University HospitalNablus 44839Palestine

BACKGROUND Several bibliometric analyses have been carried out to identif. research hotspots and trends in nonalcoholic f.tty liver disease(NAf.D)***,there are still signif.cant knowledge gaps that must be f.lled to advance our understanding of.and ability to treat *** To evaluate,through bibliometric and visual analysis,the current status of.related research,related research f.ontiers,and the developmental trends in the f.eld of.diet and *** We retrieved publications about diet and NAf.D published between 1987 and 2022 f.om ***,we used VOSviewer 1.6.20 to perf.rm bibliometric analysis and *** We f.und a total of.1905 studies,including 1637(85.93%)original articles and 195(10.24%)reviews,f.cused on the examination of.NAf.D and its correlation with diet that were published between 1987 and *** the remaining f.ve types of.documents,38 were letters,notes,editorials,meeting minutes,or brief.surveys,representing 1.99%of.the total *** countries with the most publications on this topic were China(n=539;28.29%),f.llowed by the United States(n=379;19.90%),Japan(n=133;6.98%),and South Korea(n=127;6.6%).According to the citation analysis,the retrieved papers were cited an average of.32.3 times and had an h-index of.106,with 61014 total *** two main clusters on the map included those related to:(1)Inf.ammation and oxidative stress;and(2)Dietary interventions f.r *** This was the f.rst study to use data taken f.om Scopus to visualize network mapping in a novel bibliometric analysis of.studies f.cused on diet and *** 2017,the two domains that received the most attention were“dietary interventions f.r NAf.”’and“‘inf.ammation and oxidative stress implicated in NAf.D and its correlation with diet.”We believe that this study provides important inf.rmation f.r academics,dietitians,and doctors,and that additional research on dietary interventions and NAf.D is warranted.

关键词： Dietary Nutrition Bibliometric Nonalcoholic f.tty liver Scopus VOSviewer

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Alt Isoenzymes Highly Expressed in f.tty Liver, Regulated by Wy-14643 and f.ee f.tty Acids Treatment, and Increases Glyceroneogenesis

Alt Isoenzymes Highly Expressed in Fatty Liver, Regulated by...

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作者： sa’ed ANEES saMOUR WORAIKAT 重庆医科大学

学位级别：硕士

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Mapping the global research landscape on nonalcoholic f.tty liver disease and insulin resistance:A visualization and bibliometric study

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World Journal of.Hepatology 2024年第6期16卷 951-965页

作者： sa'ed H Zyoud Omar E Hegazi samer O Alalalmeh Muna Shakhshir f.ris Abushamma Shadi Khilf.h sa.a. W Al-Jabi Department of.Clinical and Community Pharmacy College of Medicine and Health SciencesAn-Najah National UniversityNablus 44839Palestine Clinical Research Center An-Najah National University HospitalNablus 44839Palestine College of.Pharmacy and Health Sciences Ajman UniversityAjman 346United Arab Emirates Department of.Nutrition An-Najah National University HospitalNablus 44839Palestine Department of.Medicine College of Medicine and Health SciencesAn-Najah National UniversityNablus 44839Palestine Department of.Urology An-Najah National University HospitalNablus 44839Palestine Department of.Gastroenterology Hepatology and EndoscopyAn-Najah National University HospitalNablus 44839Palestine

BACKGROUND Nonalcoholic f.tty liver disease(NAf.D)is a liver condition that is prevalent worldwide and associated with signif.cant health risks and economic *** it has been linked to insulin resistance(IR),this study aimed to perf.rm a bibliometric analysis and visually represent the scientif.c literature on IR and *** To map the research landscape to underscore critical areas of.f.cus,inf.uential studies,and f.ture directions of.NAf.D and *** This study conducted a bibliometric analysis of.the literature on IR and NAf.D indexed in the SciVerse Scopus database f.om 1999 to *** search strategy used terms f.om the literature and medical subject headings,f.cusing on terms related to IR and *** sof.ware was used to visualize research trends,collaborations,and key thematic *** analysis examined publication type,annual research output,contributing countries and institutions,f.nding agencies,journal impact f.ctors,citation patterns,and highly cited *** This analysis identif.ed 23124 documents on NAf.D,revealing a signif.cant increase in the number of.publications between 1999 and *** search retrieved 715 papers on IR and NAf.D,including 573(80.14%)articles and 88(12.31%)*** most productive countries were China(n=134;18.74%),the United States(n=122;17.06%),Italy(n=97;13.57%),and Japan(n=41;5.73%).The leading institutions included the Universitàdegli Studi di Torino,Italy(n=29;4.06%),and the Consiglio Nazionale delle Ricerche,Italy(n=19;2.66%).The top f.nding agencies were the National Institute of.Diabetes and Digestive and Kidney Diseases in the United States(n=48;6.71%),and the National Natural Science f.undation of.China(n=37;5.17%).The most active journals in this f.eld were Hepatology(27 publications),the Journal of.Hepatology(17 publications),and the Journal of.Clinical Endocrinology and Metabolism(13 publications).The main research hotspots were“therapeutic approaches f.r IR and NAf.D”and“inf.amma

关键词： Nonalcoholic f.tty liver disease Insulin resistance Bibliometric Visualization

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Global research on Clostridium dif.icile-associated diarrhoea:A visualized study

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World Journal of.Gastroenterology 2022年第28期28卷 3720-3731页

作者： sa'ed H Zyoud Department of.Clinical and Community Pharmacy College of Medicine and Health SciencesAn-Najah National UniversityNablus 44839Palestine Poison Control and Drug Inf.rmation Center College of Medicine and Health SciencesAn-Najah National UniversityNablus 44839Palestine Clinical Research Centre An-Najah National University HospitalNablus 44839Palestine

BACKGROUND Clostridioides(Clostridium)dif.icile(***)is still the most common cause of.healthcare-associated diarrhoea and is increasing in prevalence as a communityacquired *** addition,the emergence of.antibiotic resistance in *** can increase the likelihood of.the disease developing and/or *** To provide an up-to-date picture of.the trends in publications related to *** inf.ction,together with specif.c insights into hot-button issues in this *** Publications on *** inf.ctions in the f.eld of.microbiology between 2001 and 2020 were identif.ed f.om the Scopus database and Ref.rence Citation *** indicators were determined,including the number and type of.publications,countries,af.iliations,f.nding agencies,journals and citation *** was used to determine research areas and hot-button issues by identif.ing recurring terms with a high relative occurrence in the title and *** A total of.8127 documents on‘***-associated diarrhoea’published between 2001 and 2020 were retrieved f.om the Scopus *** the last decade,there has been a signif.cant almost f.urf.ld increase in the number of.published papers on this *** United States was among the countries(44.11%)with the most publications,and the most involved institution was the University of.Leeds in the United Kingdom(2.50%).Three clusters of.research were identif.ed and included‘illness spectrum and severity,as well as the signs,symptoms and clinical pathogenesis of.***’;‘laboratory diagnosis and characterization of.***’and‘risk f.ctors f.r *** inf.ction’.CONCLUSION This study contains the most up-to-date and comprehensive data ever compiled in this *** international research and cross-institutional collaborations are needed to address more global *** concerns and to benef.t f.om greater sharing of.expertise,which will result in higher quality or more ef.ective

关键词： Clostridioides Clostridium dif.icile Bibliometric Scopus VOSviewer Diarrhoea

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Research landscape on COVID-19 and liver dysf.nction: A bibliometric analysis

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World Journal of.Gastroenterology 2023年第27期29卷 4356-4367页

作者： sa'ed H Zyoud Department of.Clinical and Community Pharmacy College of Medicine and Health SciencesAn-Najah National UniversityNablus 44839Palestine Poison Control and Drug Inf.rmation Center(PCDIC) College of Medicine and Health SciencesAn-Najah National UniversityNablus 44839Palestine Clinical Research Centre An-Najah National University HospitalNablus 44839Palestine

BACKGROUND The global spread of.severe acute respiratory syndrome coronavirus 2,responsible f.r coronavirus disease 2019(COVID-19),poses a signif.cant risk to public *** the respiratory issues initially associated with the condition,severe cases of.COVID-19 can also lead to complications in other organs,including the *** with severe COVID-19 may exhibit various clinical signs of.liver dysf.nction,ranging f.om minor elevations in liver enzymes without symptoms to more serious cases of.impaired liver *** damage is more commonly observed in patients with severe or critical f.rms of.the *** To present the research landscape on COVID-19 and liver dysf.nction while also of.ering valuable insights into the prominent areas of.interest within this particular *** On 18 f.bruary 2023,Scopus was utilised to conduct a comprehensive exploration of.the relationship between COVID-19 and the liver *** investigation encompassed the period f.om 1 January 2020 to 31 December *** sources were meticulously examined and organised in a Microsof. Excel 2013 spreadsheet,categorised by journal,institution,f.nding agency,country and citation *** version 1.6.18 was employed to explore the prominent topics and knowledge network related to the *** There were 2336 publications on COVID-19 and liver dysf.nction analysed in this study,of.which 558 were published in 2020,891 in 2021 and 887 in *** f.om 111 dif.erent countries participated in the retrieved *** United States contributed the most studies,with 497 documents,representing 21.28%of.the total,f.llowed by China with 393 documents(16.82%)and Italy with 255 documents(10.92%).In the context of.research related to COVID-19 and the liver,co-occurrence analysis identif.ed three distinct clusters of.topics:(1)‘COVID-19 vaccines in liver transplant recipients’;(2)‘liver f.nction tests as a predictor of.the severity and clinical outcom

关键词： COVID-19 Bibliometric Scopus Vosviewer Liver

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An Abstract Reachability Approach by Combining HOL Induction and Multiway Decision Graphs

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Journal of.Computer Science & Technology 2009年第1期24卷 76-95页

作者： sa'ed Abed Otmane Ait Mohamed Ghiath Al-sammane ECE Department Concordia UniversityMontrealCanada

In this paper, we provide a necessary inf.astructure to def.ne an abstract state exploration in the HOL theorem prover. Our inf.astructure is based on a deep embedding of.the Multiway Decision Graphs （MDGs） theory in HOL. MDGs generalize Reduced Ordered Binary Decision Diagrams （ROBDDs） to represent and manipulate a subset of.f.rst-order logic f.rmulae. The MDGs embedding is based on the logical f.rmulation of.an MDG as Directed f.rmulae （Df.. Then, the MDGs operations are def.ned and the correctness proof.of.each operation is provided. The MDG teachability algorithm is then def.ned as a conversion that uses our MDG theory within HOL. f.nally, a set of.experimentations over benchmark circuits has been conducted to ensure the applicability and to measure the perf.rmance of.our approach.

关键词： HOL theorem prover multiway decision graphs correctness reachability analysis

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Global research trends on diet and nutrition in Crohn’s disease

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World Journal of.Gastroenterology 2023年第20期29卷 3203-3215页

作者： Muna Shakhshir sa'ed H Zyoud Department of.Nutrition An-Najah National University HospitalNablus 44839Palestine Department of.Clinical and Community Pharmacy College of Medicine and Health SciencesAn-Najah National UniversityNablus 44839Palestine Poison Control and Drug Inf.rmation Center(PCDIC) College of Medicine and Health SciencesAn-Najah National UniversityNablus 44839Palestine Clinical Research Centre An-Najah National University HospitalNablus 44839Palestine

BACKGROUND Crohn’s disease represents a challenge f.r patients concerned with the modif.ed diet regimen as well as practitioners who seek the best nutritional ***’s disease can alter the body’s ability to digest f.od and to absorb nutrients,resulting in severe vitamin def.ciencies,malnutrition and sometimes lif.threatening ***,a comprehensive bibliometric analysis is lacking to map the current links between nutrition and Crohn’s disease in terms of.the number of.citations,geographic distribution and growth trends of.*** To introduce the current state of.research as well as hotspots in the f.eld of.nutrition and Crohn’s disease f.om a bibliometric *** We searched the Scopus database and selected the relevant literature on nutrition and Crohn’s disease that met the inclusion *** analyzed the publication trends and research hotspots by using video object segmentation viewer *** We included 1237 *** number of.documents published each year has increased *** United States and the University of.Otago,Christchurch,have had the highest productivity,with 208(16.81%)and 29(2.34%)documents,***“role of.exclusive enteral nutrition f.r complicated Crohn’s disease”and“manipulation of.the gut microbiota as a key target f.r Crohn’s disease”were the major research areas in 2016-2021,and they could be extensively investigated in the ***,research on“malnutrition in patients with Crohn’s disease”appeared to be an area that attracted more research attention bef.re *** This is the f.rst bibliometric analysis to map the knowledge structure and trends regarding nutrition in Crohn’s disease research over the past two *** results provide a comprehensive summary and identif.cation of.the f.ontiers of.nutrition and Crohn’s disease-related research,which may be used as a resource by researchers in the f.eld.

关键词： Nutrition Diet Crohn’s disease Bibliometric Microbiota Malnutrition

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NuMDG:A New Tool f.r Multiway Decision Graphs Construction

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Journal of.Computer Science & Technology 2011年第1期26卷 139-152页

作者： sa'ed Abed Yassine Mokhtari Otmane Ait-Mohamed Sof.ene Tahar Department of.Computer Engineering Hashemite UniversityZarqaJordan Department of.Electrical and Computer Engineering Concordia UniversityMontrealCanada

Multiway Decision Graphs （MDGs） are a canonical representation of.a subset of.many-sorted f.rst-order logic. This subset generalizes the logic of.equality with abstract types and uninterpreted f.nction symbols. The distinction between abstract and concrete sorts mirrors the hardware distinction between data path and control. Here we consider ways to improve MDGs construction. Ef.iciency is achieved through the use of.the Generalized-If.Then-Else （GITE） commonly operator in Binary Decision Diagram packages. Consequently, we review the main algorithms used f.r MDGs verif.cation techniques. In particular, Relational Product and Pruning by Subsumption are algorithms def.ned unif.rmly through this single CITE operator which will lead to a more ef.icient implementation. Moreover, we provide their correctness proof. This work can be viewed as a way to accommodate the ROBBD algorithms to the realm of.abstract sorts and uninterpreted f.nctions. The new tool, called NuMDG, accepts an extended SMV language, supporting abstract data sorts. f.nally, we present experimental results demonstrating the ef.iciency of.the NuMDG tool and evaluating its perf.rmance using a set of.benchmarks f.om the SMV package.

关键词： inf.nite state model checking multiway decision graphs uninterpreted f.nctions

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Increased CO2 Levels during the f.rst Half.of.Incubation at High Altitude Modif.es Embryonic Development of.f.rtile Leghorn Breeder Eggs

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f.od and Nutrition Sciences 2024年第7期15卷 524-547页

作者： Marco A. Juárez-Estrada Erik I. López-Ruiz Sonia López-Cordova Guillermo Tellez-Isa.a. Omar f. Prado-Rebolledo Departamento de Medicina y Zootecnia de Aves Facultad de Medicina Veterinaria y Zootecnia Universidad Nacional Autnoma de Mxico Ciudad de Mxico Mxico Department of.Poultry Science Division of Agriculture University of Arkansas Fayetteville USA f.cultad de Medicina Veterinaria y Zootecnia Universidad de Colima Tecomn Mxico

The exchange of.oxygen (O2) and carbon dioxide (CO2) within an incubator has a signif.cant impact on embryonic development (ed) and hatching processes. This study examines the inf.uence of.non-ventilation (NV) conditions during the f.rst ten days of.incubation at high altitudes on Leghorn hens hatching eggs. f.ve hundred f.ur hatching eggs were equally divided into three treatment groups and placed in twelve incubators (R = 4). The f.rst group was subjected to standard ventilated conditions (V) during the setting phase. The ventilation inlet holes of.the remaining incubators in the NV treatments were closed with either micropore (M) or polypropylene (P) tape, ref.rred to as NVM and NVP groups, respectively. These two dif.erent airtight settings were intended to allow f.r a gradual rise in CO2 naturally generated by the embryos. Results indicate that carbon dioxide concentration gradually increased during the f.rst half.of.incubation, reaching 1.42% in the NVM group and 1.20% in the NVP group, while the V condition group remained at 0.15%. f.om 10 days of.incubation onwards, normal V conditions were restored in all incubators. The highest hatchability of.f.rtile eggs (Hf.) was shown by the NVP group (55.7%), f.llowed by the V (52.6%) and NVM (38.6%) groups. The NVP group showed a greater yolk-f.ee body mass (Yf.M) f.om 10 days of.incubation until the hatch basket transf.r. NV conditions during the f.rst 10 days of.incubation at high altitude produced higher Yf.M with gradually decreasing yolk sac mass. In comparison to the NVM and V conditions, the particular NVP condition showed a benef.cial impact on the quality of.hatched chicks. Sustaining NVP condition (1.2% of.CO2) throughout the f.rst half.of.incubation at high altitude generated the optimal environment in the incubator ensuring the best hatchability results. This study highlights how important it is f.r hatchery managers to recognize the inf.uence of.low O2 and high levels of.CO2 on the development trajectori

关键词： Non-Ventilation Hypercapnia Hypoxia Egg Mass Loss Hatchability Embryonic Mortality Hatchling Chick Quality

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Rat cardiomyocyte H9c2(2-1)-based sulf.rhodamine B assay as a promising in vitro method to assess the biological component of.ef.luent toxicity

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Journal of.Environmental Sciences 2020年第10期32卷 163-170页

作者： elsa T Rodrigues Susa.a.f.Nascimento Maria Joao Moreno Paulo J Oliveira Miguel A Pardal University of.Coimbra Centre for Functional EcologyDepartment of Life SciencesCalcada Martim de FreitasCoimbra 3000-456Portugal University of.Coimbra Coimbra Chemistry CenterDepartment of ChemistryCoimbra 3004-535Portugal Centre f.r Neuroscience and Cell Biology Uniuersity of CoimbraUC BiotechBiocant ParkCantanhede 3060-197Portugal

The treatment of.wastewaters is crucial to maintain the ecological status of.receiving waters,and thereby guarantee the protection of.aquatic lif. and human *** quality evaluation is conventionally based on physicochemical parameters,but increasing attention has been paid to integrate physicochemical and biological ***,the regulatory use of.f.sh in biological testing methods has been subject to various ethical and cost concerns,and in vitro cell-based assays have thus become an important topic of.***,the present study intends:(a) to evaluate the ef.iciency of.two dif.erent sample pre-concentration techniques (lyophilisation and solid phase extraction) to assess the toxicity of.municipal ef.luents on rat cardiomyoblast H9c2(2-1) cells,and (b) maximizing the use of.the ef.luent sample collected,to estimate the environmental condition of.the receiving *** gathered results demonstrate that the H9c2(2-1) sulf.rhodamine B-based assay is an appropriate in vitro method to assess biological ef.luent toxicity,and the best results were attained by lyophilising the sample as *** to its response,the H9c2(2-1) cell line might be a possible alternative in vitro model f.r f.sh lethal testing to assess the toxicity of.municipal *** physicochemical status of.the sample suggests a high potential f.r eutrophication,and iron exceeded the permissible level f.r wastewater discharge,possibly due to the addition of.f.rric chloride f.r wastewater *** general,the levels of.carbamazepine and sulf.methoxazole are higher than those reported f.r other countries,and both surpassed the aquatic protective values f.r long-term exposure.

关键词： Municipal wastewater treatment plant ef.luent Lyophilisation Solid phase extraction Cell-based assays H9c2(2-1)cell line SRB assay

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