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Biological characteristics and clinical management of uveal and conjunctival melanoma

Oncology Research 2024年第8期32卷 1265-1285页

作者： SNJEŽANA KAŠTELAN ANA DIDOVIĆPAVIČIĆ DARIA PAŠALIĆ TAMARA NIKUŠEVA-MARTIĆ SAMIRČANOVIĆ PETRA KOVAČEVIĆ suza.a.konjevoda School of Medicine University of ZagrebZagreb10000Croatia Department of Ophthalmology Clinical Hospital DubravaZagreb10000Croatia Department of Ophthalmology Zadar General HospitalZadar23000Croatia Department of Medical Chemistry Biochemistry and Clinical ChemistrySchool of MedicineUniversity of ZagrebZagreb10000Croatia Department of Biology and Genetics School of MedicineUniversity of ZagrebZagreb10000Croatia School of Medicine University of SplitSplit21000Croatia Department of Health Studies University of ZadarZadar23000Croatia

Uveal and conjunctival melanomas are relatively rare tumors;nonetheless,they pose a signiﬁcant risk of mortality for a large number of affected *** pathogenesis of melanoma at different sites is very similar,however,the prognosis for patients with ocular melanoma remains unfavourable,primarily due to its distinctive genetic proﬁle and tumor *** of considerable advances in understanding the genetic characteristics and biological behaviour,the treatment of uveal and conjunctival melanoma remains a formidable *** enhance the prospect of success,collaborative efforts involving medical professionals and researchers in theﬁelds of ocular biology and oncology are *** data show a lack of well-designed randomized clinical trials and limited beneﬁts in current forms of treatment for these *** advancements in the development of effective melanoma therapeutic strategies,all current treatments for uveal melanoma(UM)and conjunctival melanoma(CoM)remain unsatisfactory,resulting in a poor long-term *** trials offer hope for positive outcomes in advanced and metastatic tumors.A more comprehensive understanding of the genetic and molecular abnormalities involved in the development and progression of ocular melanomas opens the way for the development of personalized therapy,with various potential therapeutic targets currently under *** comprehension of the molecular pathogenesis of UM and CoM and their speciﬁcities may aid in the development of new and more effective systemic therapeutic agents,with the hope of improving the prognosis for patients with metastatic disease.

关键词： Uveal melanoma Conjunctival melanoma Genetic characteristics Immune checkpoint inhibitors Target molecular inhibitors

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Analysis of Cotton Yarn Properties Spun on Aerodynamic Compact and Open-End Rotor Spinning

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Journal of Textile Science and Technology 2021年第1期7卷 22-40页

作者： Md. Rafiqul Islam suza Ahmed Md. Abubakar Siddik Sadik M. Ashique Department of Textile Engineering National Institute of Textile Engineering and Research (NITER) Nayarhat Savar Dhaka Bangladesh

This article presents a comparative analysis of the properties of cotton yarn spun on aerodynamic compact spinning and open-end rotor spinning systems. Yarn samples with a linear density of 50 Tex, 37 Tex, 30 Tex, 25 Tex, and 20 Tex were spun both on the aerodynamic compact and rotor spinning systems using the same finisher drawn sliver of medium staple cotton which were produced by a specific mixing. The quality parameters such as mass variation, imperfection index, hairiness, and tensile behavior (strength in count strength product, elongation percentage) of the yarn samples were assessed and analyzed. The results revealed that aerodynamic compact spun yarn had a lower unevenness and mass variation, a higher imperfection in case of a finer count, less hairiness, higher tensile strength, and lower elongation% compared to the open-end rotor spun yarn samples. Finally, paired- samples t-test and regression analysis were carried out by using IBM SPSS 25 to check the significance of yarn quality parameters and correlation among them.

关键词： Compact Yarn Rotor Yarn Imperfection Hairiness Tensile Strength

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Analysis of the Adsorption of Toxic Chromium (VI) by Untreated and Chitosan Treated Banana and Areca Fiber

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Journal of Textile Science and Technology 2020年第2期6卷 81-106页

作者： Hosne Ara Begum A. K. M. Monjurul Haque Md. Didarul Islam M. Mehedi Hasan suza Ahmed Md. Razzak Ruhul Amin Khan Department of Yarn Engineering Bangladesh University of Textiles Dhaka Bangladesh Department of Applied Science & Chemical Engineering University of Dhaka Dhaka Bangladesh Department of Fabric Engineering Bangladesh University of Textiles Dhaka Bangladesh Institute of Radiation and Polymer Technology Bangladesh Atomic Energy Commission Dhaka Bangladesh

This paper work involves bunch experiments to investigate the effect of contact time, pH, and adsorbent dose on the extent of adsorption by bio-composites. Adsorption capacity of Chromium (VI) onto chitosan coated with banana and areca fiber was investigated in a batch system by considering the effects of various parameters like contact time, initial concentration, pH and adsorbent dose. The chitosan and fibers (banana and areca) were then cross-linked with glutaraldehyde to remove chromium [Cr (VI)] from water via static adsorption. It was found that optimum chromium absorption capacity of chitosan was assessed at pH of 2.5 to 4.5 and contact time of 30 to 180 minutes for raw banana and areca fiber and for chitosan treated banana & areca fiber. Though optimum adsorption of chromium of chitosan was measured 34.17 ppm (85.42%) from a 100 ml solution containing 40 parts per million (ppm) of Cr (VI) at 120 minutes, pH of 3.0 and 120 milligram (mg) adsorbent dose size, use of composite will be more favorable in the point of environmental concern as well as low cost because chitosan preparation is comparatively costly then banana and areca fiber. On the other hand, untreated banana and areca fiber optimum adsorption of chromium measured 3.65 ppm (9.1%) at 180 min and, pH of 4.5 and 140 mg adsorbent dose size and 3.76 ppm (9.4%) at 180 min, pH of 4.5 and 160 mg adsorbent dose size respectively. In case of chitosan treated banana fiber, it was observed that adsorption was increased from 17.664 to 30.057 (75.14%). On the other hand, for areca fiber with chitosan, it was observed that adsorption was increased from 21.664 to 30.156 (75.39%) ppm. The Langmuir and Freundlich adsorption models were used for the mathematical description of the adsorption of chromium ion onto composites and it was found that the Langmuir adsorption isotherm was more fitted models which mean that a monolayer adsorption surface was created. After analyzing from IBM SPSS 25 software, we got the stand

关键词： Adsorption Heavy Metal Chitosan Banana Fiber Areca Fiber Toxicity

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