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Waggle needling Yanglingquan(GB34) enhances cerebral blood flow and ameliorates condition of spastic paresis in rats with middle cerebral artery occlusion induced by surgical nylon suture

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Journal of Traditional Chinese Medicine 2023年第3期43卷 514-522页

作者： ZHANG Zhou MU Jiedan MA Liangxiao YU Wenyan sun tianyi QIAN Xu TIAN Yuan ZHANG Yidan WANG Junxiang School of Acupuncture-Moxibustion and Tuina Beijing University of Chinese MedicineBeijing 100029China the Key Unit of State Administration of Traditional Chines Medicine Evaluation of Characteristic Acupuncture TherapyBeijing 100029China School of Nursing Beijing University of Chinese MedicineBeijing 100029China

OBJECTIVE:To evaluate the therapeutic efficacy and the influence on cerebral blood supply of waggle needling Yanglingquan(GB34) on spastic paresis(SP) rats after middle cerebral artery occlusion(MCAO) induced and investigate its mechanism of relieving neurobehavior ***:SP rat model was produced by permanent *** were divided into five groups:blank control group(Control),sham operation group(Sham),model group(Model),waggle needling group(WN) and perpendicular needling group(PN).SP rats were treated with acupuncture from day 3 after MCAO,once a day for 6 *** modified neurological severity score(m NSS) and modified Ashworth scale(MAS) were conducted on days 0,1,3,5,7 and *** blood flow(CBF) in ischemic cortex was measured by laser speckle imaging 5 min pre ischemia,5 min post ischemia,and after intervention on day *** rats were sacrificed at day 9 and the protein and m RNA expressions of γ2 subunit of the γ-aminobutyric acid receptor A(GABAAγ2) and K+-Cl-cotransporter 2(KCC2) in the ischemic cortex and lumber enlargement was measured by Western blotting and real-time quantitative polymerase chain ***:Both Control and Sham groups showed no changes in m NSS and MAS scores and in the regional *** with Model group,both WN and PN treatments significantly ameliorated neurological deficit(P < 0.01),decreased muscle tone(P < 0.05),and enhanced CBF(P < 0.001) in SP rats;moreover,WN showed superior effects than PN(P < 0.001).In line with the improvement in neurobehavior,acupuncture interventions up-regulated the expressions of GABAAγ2 and KCC2 in the ischemic cortex as well as lumber enlargement(P < 0.01) in SP rats,and those changes were more obvious in WN(P < 0.05).CONCLUSIONS:Acupuncture at Yanglingquan(GB34) enhanced cerebral blood flow and ameliorated SP in permanent MCAO rats,while waggle needling was superior to regular perpendicular *** needling Yanglingquan(GB34) would be a potential complementary therapy

关键词： spastic paresis acupuncture cerebrovascular circulation laser speckle imaging γ2 subunit of theγ-aminobutyric acid receptor A K+-Cl-cotransporter 2

AN ASSET EXPLORED——On the Use of Chinese in Teaching English to Adult Chinese Students

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外语教学 1980年第3期 25-32页

作者： sun tianyi Yao Fusheng

(continued) In our teaching process, Chinese is used(a)to give instructions,(b) to create opportunities for practice; (c) to obtain feedback from the students;and (d) to train the students in translation. It is of course not advisable to revert to Chinese as the sole medium of instruction, nor even as the major medium, Giving instructions in English is a chal-

关键词： On the Use of Chinese in Teaching English to Adult Chinese Students AN ASSET EXPLORED

Correlating O-deﬁciency and luminescence property of Tb^(3+)þdoped SrO

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Advanced Powder Materials

Advanced Powder Materials 2023年第3期2卷 28-35页

作者： Kaina Wang Jipeng Fu Shuqin Chang Xuan sun tianyi sun Su Zhang Ran Pang Lihong Jiang Xiaojun Kuang Evan Wenbo Zhao Chengyu Li Shiqing Xu Mingxue Tang Key Laboratory of Rare Earth Optoelectronic Materials and Devices of Zhejiang Province Institute of Optoelectronic Materials and DevicesChina Jiliang University310018 HangzhouChina Center for High Pressure Science and Technology Advanced Research 100094 BeijingChina State Key Laboratory of Rare Earth Resources Utilization Changchun Institute of Applied ChemistryChinese Academic of Sciences130022 ChangchunChina Guangxi Key Laboratory of Electrochemical and Magneto-chemical Functional Materials College of Chemistry and BioengineeringGuilin University of TechnologyGuilin 541004PR China Magnetic Resonance Research Center Institute for Molecules and MaterialsRadboud UniversityNijmegen6525AJthe Netherlands

Cubic rock salt can lower down or break the rare earth transition barrier through interstitial or vacancy defects owing to its great deformation and rotationﬂ***,we demonstrate that oxygen vacancies in SrO are induced by proper oxidization and atmosphere adjustment,resulting in defects with various depths and crystalﬁeld *** thermally assisted tunneling from defects to 5 D_(4) state and electronic population decrease on 5 D_(3) state of Tb^(3+)þare observed by the deformation of adjacent oxygen octahedral ***,the asprepared SrO:0.01 Tb^(3+)þphosphors,commercial BaMgAl10O17:Eu^(2+)þblue phosphor,and CaAlSiN3:Eu^(2+)þred phosphor are mixed and coated onto 280 nm deep-ultraviolet LED chip to assemble white light-emitting LED *** LEDs show CCT of 3850 K,4136 K,and 4741 K,with color rendering index of 90.3,90.8,and 92.1,*** insights will advance the fundamental knowledge of crystal engineering in cubic rock salt,and enable new ways to manipulate energy transfer and electronic transition via defects.

关键词： Oxygen vacancy Spectral modulation Long-lasting phosphorescence White LEDs Energy transfer

Correlations Between Single Nucleotide Polymorphisms,Cognitive Dysfunction,and Postmortem Brain Pathology in Alzheimer's Disease Among Han Chinese

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Neuroscience Bulletin 2019年第2期35卷 193-204页

作者： Qian Yang Kang Chen Hanlin Zhang Wanying Zhang Changlin Gong Qing Zhang Pan Liu tianyi sun Yuanyuan Xu Xiaojing Qian Wenying Qiu Chao Ma Institute of Basic Medical Sciences Department of Human AnatomyHistology and EmbryologyNeuroscience CenterChinese Academy of Medical SciencesSchool of Basic MedicinePeking Union Medical College Joint Laboratory of Anesthesia and Pain Peking Union Medical College Eight-Year MD Program Peking Union Medical College Johns Hopkins Bloomberg School of Public Health National Experimental Teaching Demonstration Center of Basic Medicine Peking Union Medical College

In this study, the distribution of five Alzheimer's disease(AD)-related single nucleotide polymorphisms(SNPs) in the Han population was examined in combination with the evaluation of clinical cognition and brain pathological analysis. The associations among SNPs,clinical daily cognitive states, and postmortem neuropathological changes were analyzed in 110 human brains from the Chinese Academy of Medical Sciences/Peking Union Medical College(CAMS/PUMC) Human Brain *** ?4(OR = 4.482, P = 0.004), the RS2305421 GG genotype(adjusted OR = 4.397, P = 0.015), and the RS10498633 GT genotype(adjusted OR = 2.375,P = 0.028) were associated with a higher score on the ABC(Ab plaque score, Braak NFT stage, and CERAD neuritic plaque score) dementia scale. These results advance our understanding of the pathogenesis of AD,the relationship between pathological diagnosis and clinical diagnosis, and the SNPs in the Han population for future research.

关键词： Human brain bank Alzheimer's disease APOEε4 ADAM10 SLC24A4

Comparison of Reference Genes for Transcriptional Studies in Postmortem Human Brain Tissue Under Different Conditions

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Neuroscience Bulletin 2019年第2期35卷 225-228页

作者： Qing Zhang Hanlin Zhang Fan Liu Qian Yang Kang Chen Pan Liu tianyi sun Chao Ma Wenying Qiu Xiaojing Qian Department of Human Anatomy Histology and EmbryologySchool of Basic Medicine Peking Union Medical CollegeInstitute of Basic Medical Sciences Chinese Academy of Medical Sciences Joint Laboratory of Anesthesia and Pain Peking Union Medical College Chinese Academy of Medical Sciences Eight-Year MD Program Peking Union Medical College

Dear Editor Research on neurodegenerative diseases is a hot topic worldwide[1],and MRI,genetics and epigenetics,and animal models have been commonly *** species differences,research on human brain samples is irreplaceable(2)Many countries and regions have built brain banks to collect and store brain tissue from *** provided by a brain bank can be used to study synaptic structure,protein,DNA,RNA[3,4],and lipids to illuminate the pathological mechanisms underlying neurodegenerative *** brain tissue is used for gene expression research,the quantitative real-time polymerase chain reaction(RT-qPCR)is an accurate method,which simultaneously amplifies and quantifies the expression of target genes by measuring the intensity of fluorescence in each PCR cycle.

关键词： TBP Comparison of Reference Genes for Transcriptional Studies in Postmortem Human Brain Tissue Under Different Conditions

Analgesic effects and hemodynamic mechanisms of perpendicular and transverse needling at Sanyinjiao(SP 6) in patients with primary dysmenorrhea: A randomized controlled trial

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Journal of Traditional Chinese Medical Sciences 2021年第3期8卷 248-256页

作者： Ali Mohammadi Mohammad Reza Afshari Fard Liangxiao Ma Jiedan Mu tianyi sun Wenyan Yu Sanaz Dehghani Mohammad Hossein Ayati School of Acupuncture-Moxibustion and Tuina Beijing University of Chinese MedicineBeijing102488China Faculty of Medicine Shiraz Medical University of IranBeijing102488China Qeshem International Branch Islamic Azad University of Medical ScienceHormozgan***Iran School of Traditional Medicine Tehran University of Medical SciencesHormozgan***Iran

Objective: To explore the analgesic effects and uterine hemodynamics of perpendicular needling(PN)and transverse needling(TN) at SP 6 in patients with primary dysmenorrhea(PD).Methods: In this randomized controlled trial, patients with PD diagnosed with cold-dampness congealing pattern were randomly assigned in a ratio of 1:1 to receive PN or TN at bilateral SP 6 for 10 *** was performed when the menstrual pain score was over 40 mm on the first day of menstruation, as measured using the visual analog scale for pain(VAS-P). The primary outcome was average menstrual pain(VAS-P). Secondary outcomes included the pulsatility index(PI), resistance index(RI), and systolic-diastolic peaks ratio(S/D) in uterine arteries as measured using color Doppler ultrasonography;anxiety as assessed using the Hamilton Anxiety Rating Scale(HAMA), blood pressure(BP),and heart rate(HR).Results: Forty-eight patients completed the study. The TN group exhibited a significant reduction in VAS-P scores(-5.71 mm, 95% confidence interval(CI): -8.78, -2.63, P =.001), RI values(-0.05, 95% CI:-0.09, -0.01, P=.015), and HAMA values(-2.50, 95% CI: -4.78, -0.22, P=.032) when compared with the PN group. No significant differences in PI, S/D, BP, or HR values were observed between the two groups(P >.05).Conclusion: TN at SP 6 was superior to PN in alleviating menstrual pain and anxiety in patients with *** analgesic effect of TN may be due to its better ability to improve uterine arterial blood flow via decreases in RI values.

关键词： Primary dysmenorrhea Perpendicular needling Transverse needling Sanyinjiao(SP 6) Visual analog scale Hemodynamic mechanism

发散冷却和前缘槽缝射流作用下涡轮静叶端壁流动结构的研究

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西安交通大学学报 2022年第1期56卷 120-129页

作者：孙添一李志刚李军西安交通大学叶轮机械研究所西安710049

数值研究了无发散冷却与3种发散冷却气质量流量比下的涡轮静叶端壁附近涡结构、总压损失系数和端壁、叶表绝热冷却有效度以及两种冷却气在端壁上的流动结构。研究表明:发散冷却气质量流量比由5%增加至7%时,进口截面端壁附近的总压峰值升... 详细信息

数值研究了无发散冷却与3种发散冷却气质量流量比下的涡轮静叶端壁附近涡结构、总压损失系数和端壁、叶表绝热冷却有效度以及两种冷却气在端壁上的流动结构。研究表明:发散冷却气质量流量比由5%增加至7%时,进口截面端壁附近的总压峰值升高3.7%,峰值区流体在叶片前缘滞止后向上卷起形成冲击涡;发散冷却流量增加会增强冲击涡而吸力面角区涡对被削弱。低流量冷却气会使整体总压损失降低,而发散冷却气质量流量比由5%升高至7%时总压损失增加4.5%。发散冷却气注入时,冲击涡会将冷却气携带至叶表,在压力面形成显著的泛冷却效果;发散冷却气质量流量比增加至7%会使冲击涡纵向伸长并分裂出三次涡。发散冷却贡献占比的计算结果表明,边界层分离线上游端壁由槽缝射流冷却气覆盖,而叶表和下游端壁的冷却由发散冷却主导。静叶端壁流动结构受到上游燃烧室内壁发散冷却的显著影响,并将改变端壁冷却特性。

关键词：静叶端壁发散冷却槽缝射流流动结构

Development and Cleaning Cycle Optimization of Photovoltaic Module Cleaning Robot

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Development and Cleaning Cycle Optimization of Photovoltaic ...

工作记忆中转换加工的内源性准备和外源性调节

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作者： Lilei Jiang Bo Zhao Shengxian Cao Siyuan Fan tianyi sun School of Automation Engineering Northeast Electric Power University

In order to achieve a highly automated and low-cost solution to replace regular manual cleaning and improve the economic benefits of distributed photovoltaic(PV) system,an intelligent operation and maintenance cleaning robot and cleaning cycle optimization method was developed in this *** three-dimensional model of the moving vehicle,cleaning roller and control system of the cleaning robot are *** then the cleaning cycle optimization model of dust on PV modules was built based on the developed cleaning *** test and optimization results showed that using the robot to clean PV modules with dust accumulation of4 g/m,6 g/m and 8 g/m,and the cleaning efficiency reached 92.14%,91.04%,and 90.09%,*** with manual cleaning,the optimal cleaning cycle was reduced from 48.3 days to 26.5 days,and the cleaning cost was reduced from 223200 yuan to 30600 yuan for 2 MW distributed PV *** cleaning cost is greatly reduced,while the cleaning frequency is increased,and the power generation is improved.

关键词： Photovoltaic modules dust accumulation cleaning robot cleaning cycle optimization cost cleaning efficiency

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心理学报 2007年第6期39卷 985-993页

作者：郭春彦孙天义首都师范大学心理系北京100037

考察工作记忆中转换加工的控制过程。采用"任务转换"范式,探究预知条件(实验一)和未预知条件(实验二)下的转换加工。结果发现:(1)任务重复与任务转换是两个不同的过程;无论是在预知条件还是未预知条件下都出现任务重复效应显著大于任务... 详细信息

考察工作记忆中转换加工的控制过程。采用"任务转换"范式,探究预知条件(实验一)和未预知条件(实验二)下的转换加工。结果发现:(1)任务重复与任务转换是两个不同的过程;无论是在预知条件还是未预知条件下都出现任务重复效应显著大于任务转换效应;(2)验证了转换加工包括内源性准备和外源性调节两个不同的加工过程,内源性准备只是任务设置重建的一部分;(3)对先后呈现的两个任务(任务1—任务2:任务重复或任务转换)在预知重复、预知转换和未预知条件下,任务2对任务1的影响不同,存在前瞻性记忆效应。由此推断转换加工的心理过程是:在预知情况下,任务1呈现后即启动内源性准备,直到任务2呈现时,通过外源性调节最终完成任务转换;而在未预知情况下,只能依赖外源性调节来实现。

关键词：转换加工转换代价内源性准备外源性调节前瞻性记忆效应