Analgesic effects and hemodynamic mechanisms of perpendicular and transverse needling at Sanyinjiao(SP 6) in patients with primary dysmenorrhea: A randomized controlled trial

作     者：Ali Mohammadi Mohammad Reza Afshari Fard Liangxiao Ma Jiedan Mu Tianyi Sun Wenyan Yu Sanaz Dehghani Mohammad Hossein Ayati Ali Mohammadi;Mohammad Reza Afshari Fard;Liangxiao Ma;Jiedan Mu;Tianyi Sun;Wenyan Yu;Sanaz Dehghani;Mohammad Hossein Ayati

作者机构：School of Acupuncture-Moxibustion and TuinaBeijing University of Chinese MedicineBeijing102488China Faculty of MedicineShiraz Medical University of IranBeijing102488China Qeshem International BranchIslamic Azad University of Medical ScienceHormozgan***Iran School of Traditional MedicineTehran University of Medical SciencesHormozgan***Iran 

出 版 物：《Journal of Traditional Chinese Medical Sciences》 (中医科学杂志（英文）)

年 卷 期：2021年第8卷第3期

页      面：248-256页

学科分类：1007[医学-药学(可授医学、理学学位)] 1005[医学-中医学] 1002[医学-临床医学] 100512[医学-针灸推拿学] 10[医学] 

基　　金：funded by the Longitudinal Research Project of BUCM (2018-ZXFZJJ-010) 

主　　题：Primary dysmenorrhea Perpendicular needling Transverse needling Sanyinjiao(SP 6) Visual analog scale Hemodynamic mechanism 

摘      要：Objective: To explore the analgesic effects and uterine hemodynamics of perpendicular needling(PN)and transverse needling(TN) at SP 6 in patients with primary dysmenorrhea(PD).Methods: In this randomized controlled trial, patients with PD diagnosed with cold-dampness congealing pattern were randomly assigned in a ratio of 1:1 to receive PN or TN at bilateral SP 6 for 10 *** was performed when the menstrual pain score was over 40 mm on the first day of menstruation, as measured using the visual analog scale for pain(VAS-P). The primary outcome was average menstrual pain(VAS-P). Secondary outcomes included the pulsatility index(PI), resistance index(RI), and systolic-diastolic peaks ratio(S/D) in uterine arteries as measured using color Doppler ultrasonography;anxiety as assessed using the Hamilton Anxiety Rating Scale(HAMA), blood pressure(BP),and heart rate(HR).Results: Forty-eight patients completed the study. The TN group exhibited a significant reduction in VAS-P scores(-5.71 mm, 95% confidence interval(CI): -8.78, -2.63, P =.001), RI values(-0.05, 95% CI:-0.09, -0.01, P=.015), and HAMA values(-2.50, 95% CI: -4.78, -0.22, P=.032) when compared with the PN group. No significant differences in PI, S/D, BP, or HR values were observed between the two groups(P .05).Conclusion: TN at SP 6 was superior to PN in alleviating menstrual pain and anxiety in patients with *** analgesic effect of TN may be due to its better ability to improve uterine arterial blood flow via decreases in RI values.