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Chinese Chemical Letters 2024年第10期35卷 374-378页

作者： Lin Li Bingjun sun Jin sun Lin Chen Zhonggui He Department of Pharmacy Women and Children's Hospital of Chongqing Medical University/Chongqing Health Center for Women and Children Department of Pharmaceutics Wuya College of Innovation Shenyang Pharmaceutical University

Chemotherapy has been recommended as the standard protocol for triple-negative breast cancer （TNBC）at the advanced ***,the current treatment is unsatisfactory due to inefficient drug accumulation and rapid ***,rational design of advanced drug delivery systems that can induce multiple cell death pathways is a promising strategy to combat *** is a powerful non-apoptotic cell death modality,showing potential in tumor ***,we propose a binary prodrug nanoassemblies that combines chemotherapy with ferroptosis for TNBC *** this system,paclitaxel is linked with paracetamol （ferroptosis activator） by a disulfide linkage to construct self-assembly ***,2-distearoyl-sn-glycerol-3-phosphoethanolamine-N-methyl（polyethylene glycol）-2000-tyrosine (DSPE-PEG2k-tyrosine) is applied for large neutral amino acid transporter 1 （LAT1） targeting,which is highly expressed in *** prodrug nanoassemblies exhibit good stability and a glutathione （GSH）-responsive release ***,the LAT1-targeted nanoassemblies show stronger cytotoxicity,higher cellular uptake,and more obvious ferroptosis activation than non-decorated *** a TNBC mice model,the prodrug nanoassemblies demonstrate strong anti-tumor *** application of ferroptosis-assisting chemotherapy may provide a promising strategy for TNBC therapy.

关键词： Ferroptosis LAT1 Paclitaxel Prodrug nanoassemblies Triple-negative breast cancer

Bioinspired nanocomposites with self-adaptive mechanical properties

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Nano Research 2024年第2期17卷 633-648页

作者： Grant Kitchen Bohan sun sung Hoon Kang 13400 N Charles St Department of Materials Science and EngineeringJohns Hopkins UniversityBaltimore 21218USA 23400 N Charles St Department of Mechanical EngineeringJohns Hopkins UniversityBaltimore 21218USA 33400 N Charles St Hopkins Extreme Materials InstituteJohns Hopkins UniversityBaltimore 21218USA

Conventional synthetic materials have fixed mechanical properties and suffer defects,damage,and degradation over *** makes them unable to adapt to changing environments and leads to limited ***,self-adaptive materials inspired by natural materials have emerged as a solution to address these *** the ability to change their mechanical properties based on changing mechanical environments,repairing defects,and maintaining their mechanical properties,these materials can lead to improved performance while decreasing *** this review,we explore self-adaptive phenomena found in nature that have inspired the development of synthetic self-adaptive materials,and the mechanisms that have been employed to create the next generation of *** potential applications of these materials,the challenges that existing approaches face,and future research opportunities are also discussed.

关键词： nanocomposites self-adaptive materials bioinspired materials force-activated resilience

Enhanced gas production and CO_(2) storage in hydrate-bearing sediments via pre-depressurization and rapid CO_(2) injection

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Chinese Journal of Chemical Engineering 2024年第3期67卷 126-134页

作者： Hongnan Chen Yifei sun Bojian Cao Minglong Wang Ming Wang Jinrong Zhong Changyu sun Guangjin Chen State Key Laboratory of Heavy Oil Processing China University of PetroleumBeijing 102249China School of Chemistry and Chemical Engineering Changsha University of Science&TechnologyChangsha 410114China

Carbon emission reduction and clean energy development are urgent demands for mankind in the coming *** an efficient CO_(2) storage method can significantly reduce CO_(2) emissions in the short *** this study,we attempted to construct sediment samples with different residual CH_(4) hydrate amounts and reservoir conditions,and then investigate the potentials of both CO_(2) storage and enhanced CH_(4) recovery in depleted gas hydrate deposits in the permafrost and ocean zones,*** results demonstrate that CO_(2) hydrate formation rate can be significantly improved due to the presence of residual hydrate seeds;However,excessive residual hydrates in turn lead to the decrease in CO_(2) storage *** by the T-P conditions of the reservoir,the storage amount of liquid CO_(2) can reach 8 times that of gaseous CO_(2),and CO_(2) stored in hydrate form reaches 2-4 ***,we noticed two other advantages of this *** is that CO_(2) injection can enhance CH_(4) recovery rate and increases CH_(4) recovery by 10%-20%.The second is that hydrate saturation in the reservoir can be restored to 20%-40%,which means that the solid volume of the reservoir avoids serious ***,this is crucial for protecting the goaf *** summary,this approach is greatly promising for high-efficient CO_(2) storage and safe exploitation of gas hydrate.

关键词： Hydrate Depressurization CO_(2) storage CH_(4) production Reservoir remediation

Fixed-Time Consensus-Based Nash Equilibrium Seeking

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IEEE/CAA Journal of Automatica Sinica 2024年第1期11卷 267-269页

作者： Mengwei sun Jian Liu Lu Ren Changyin sun the Institutes of Physical Science and Information Technology Anhui UniversityHefei 230601China IEEE the School of Automation and the Key Laboratory of Measurement and Control of Complex System of Engineering Ministry of EducationSoutheast UniversityNanjing 210096China the School of Artificial Intelligence and the Engineering Research Center of Autonomous Unmanned System Technology Ministry of EducationAnhui UniversityHefei 230601China

Dear Editor,This letter examines the fixed-time stability of the Nash equilibrium(NE)in non-cooperative *** propose a consensus-based NE seeking algorithm for situations where players do not have perfect information and communicate via a topology *** proposed algorithm can achieve NE in a fixed time that does not depend on initial conditions and can be adjusted in advance.

关键词： Fixed seeking letter

Borohydride Ammoniate Solid Electrolyte Design for All-Solid-State Mg Batteries

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Energy & Environmental Materials 2024年第1期7卷 100-106页

作者： Yuepeng Pang Zhengfang Nie Fen Xu Lixian sun Junhe Yang Dalin sun Fang Fang Shiyou Zheng School of Materials and Chemistry University of Shanghai for Science and TechnologyShanghai 200093China Guangxi Key Laboratory of Information Materials&Guangxi Collaborative Innovation Centre of Structure and Property for New Energy and Materials Guilin University of Electronic TechnologyGuilin 541004China Department of Materials Science Fudan UniversityShanghai 200433China

Searching for novel solid electrolytes is of great importance and challenge for all-solid-state Mg *** this work,we develop an amorphous Mg borohydride ammoniate,Mg(BH_(4))_(2)·2NH_(3),as a solid Mg electrolyte that prepared by a NH_(3)redistribution between 3D framework-γ-Mg(BH_(4))_(2)and Mg(BH_(4))_(2)·6NH_(3).Amorphous Mg(BH_(4))_(2)·2NH_(3)exhibits a high Mg-ion conductivity of 5×10^(-4)S cm^(-1)at 75℃,which is attributed to the fast migration of abundant Mg vacancies according to the theoretical ***,amorphous Mg(BH_(4))_(2)·2NH_(3)shows an apparent electrochemical stability window of 0-1.4 V with the help of in-situ formed interphases,which can prevent further side reactions without hindering the Mg-ion *** on the above superiorities,amorphous Mg(BH_(4))_(2)·2NH_(3)enables the stable cycling of all-solid-state Mg cells,as the critical current density reaches 3.2 mA cm^(-2)for Mg symmetrical cells and the reversible specific capacity reaches 141 mAh g^(-1)with a coulombic efficiency of 91.7%(first cycle)for Mg||TiS_(2)cells.

关键词： all-solid-state Mg batteries amorphization Mg borohydride ammoniate Mg vacancy migration solid electrolyte

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沥青路面级配碎石基层强度控制标准研究

山西建筑 2020年第2期46卷 95-97页

作者：李如敏孙明山河北省高速公路石黄管理处

为了优化沥青路面级配碎石基层的结构参数,提高沥青路面的耐久性,基于重交通沥青路面的荷载响应规律及材料特性,从力学响应入手,开展沥青路面级配碎石基层的强度控制标准研究,为级配碎石基层沥青路面的施工与设计提供参考。

关键词：沥青路面级配碎石基层力学响应强度标准

Cryogenian and Ediacaran integrative stratigraphy,biotas,and paleogeographical evolution of the Qinghai-Tibetan Plateau and its surrounding areas

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Science China Earth Sciences 2024年第4期67卷 919-949页

作者： Lang sun Malik Muhammad Saud Sajid KHAN Chuan YANG Zhixin sun Bing PAN Shehryar AHMED Lanyun MIAO Weichen sun Chunlin HU Xiaojuan sun Cui LUO Bo CHEN Zongjun YIN Fangchen ZHAO Guoxiang LI Maoyan ZHU State Key Laboratory of Palaeobiology and Stratigraphy Nanjing Institute of Geology and PalaeontologyChinese Academy of SciencesNanjing 210008China College of Earth and Planetary Sciences University of Chinese Academy of SciencesBeijing 100049China

The complex evolutionary history of the Qinghai-Tibetan Plateau and its surrounding areas,including the continental blocks(Indian,Lhasa,South Qiangtang,Tarim,Olongbuluk,Central Qilian,Alxa,North China,Yangtze,Central Iran and Oman)and the orogenic belts between them,has long been the frontier in Earth science *** Cryogenian and Ediacaran strata are extensively distributed in these ***,relatively complete Cryogenian and Ediacaran successions have been discovered in Oman,Indian,Yangtze,and Tarim blocks,while only the Ediacaran successions have been reported in Iran,the South Qiangtang,Central Qilian,Alxa,and North China *** on previous studies together with the integration of new materials and advancement obtained through the Second Tibetan Plateau Scientific Expedition and Research,this review aims to synthesize a correlative stratigraphic framework of the representative Cryogenian and Ediacaran sequences from the Qinghai-Tibetan Plateau and its surrounding ***,the Cryogenian and Ediacaran biotas and major geological events in these areas are comprehensively discussed in aspects of current research *** results indicate that,in general,Ediacaran fossils of each area exhibit distinct features in preservation and assemblage composition,but the typical late Ediacaran fossils Cloudina and Shaanxilithes have been reported from most of these *** addition to the two global Cryogenian glaciations,late Ediacaran glaciogenic deposits are extensively recorded in the areas within and around the northern QinghaiTibetan Plateau(including the North China,Alxa,Central Qilian,Olongbuluk,and Tarim blocks,and the North Qilian Accretionary Belt),as well as central and southern ***,further research is required to determine the age,distribution,and origin of these late Ediacaran glaciogenic ***,the middle Ediacaran DOUNCE/Shuram Excursion is widely documented in the Qinghai-Tibetan Plateau and its surroundi

关键词： Qinghai-Tibetan Plateau Cryogenian Ediacaran Stratigraphy Palaeogeography Biota Gondwana

Invisible vapor catalysis in graphene growth by chemical vapor deposition

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Nano Research 2024年第5期17卷 4259-4269页

作者： Xiucai sun Xiaoting Liu Zhongti sun Xintong Zhang Yuzhu Wu Yeshu Zhu Yuqing Song Kaicheng Jia Jincan Zhang Luzhao sun Wan-Jian Yin Zhongfan Liu Center for Nanochemistry Beijing Science and Engineering Center for NanocarbonsBeijing National Laboratory for Molecular ScienceCollege of Chemistry and Molecular EngineeringPeking UniversityBeijing 100871China Beijing Graphene Institute(BGI) Beijing 100095China Academy for Advanced Interdisciplinary Studies Peking UniversityBeijing 100871China School of Materials Science and Engineering Jiangsu UniversityZhenjiang 212013China Department of Engineering University of CambridgeCambridge CB30FAUK College of Energy Soochow Institute for Energy and Materials InnovationS(SIEMIS)Jiangsu Provincial Key Laboratory for Advanced Carbon Materials and Wearable Energy TechnologiesSoochow UniversitySuzhou 215006China

Vapor catalysis was recently found to play a crucial role in superclean graphene growth via chemical vapor decomposition(CVD).However,knowledge of vapor-phase catalysis is scarce,and several fundamental issues,including vapor compositions and their impact on graphene growth,are ***,by combining density functional theory(DFT)calculations,an ideal gas model,and a designed experiment,we found that the vapor was mainly composed of Cui clusters with tens of *** vapor pressure was estimated to be~10^(-12)-10^(-1)1 bar under normal low-pressure CVD system(LPCVD)conditions for graphene growth,and the exposed surface area of Cui clusters in the vapor was 22-269 times that of the Cu substrate surface,highlighting the importance of vapor *** calculations show Cu clusters,represented by Cu17,have strong capabilities for adsorption,dehydrogenation,and decomposition of *** exhibit an adsorption lifetime and reaction flux six orders of magnitude higher than those on the Cu surface,thus providing a sufficient supply of active C atoms for rapid graphene growth and improving the surface cleanliness of the synthesized *** experimental validation showed that increasing the amount of Cu vapor improved the as-synthesized graphene growth rate and surface *** study provides a comprehensive understanding of vapor catalysis and the fundamental basis of vapor control for superclean graphene rapid growth.

关键词： vapor catalysis graphene growth chemical vapor deposition first-principles calculation

A noval iron-capturing nanocomposites against biofilms for disrupting bacterial nutritional balance

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Science China Chemistry 2024年第6期67卷 1760-1761页

作者： Jinying Lin Qihang Ding Yao sun Department of Oral Implantology Jilin Provincial Key Laboratory of Tooth Development and Bone RemodelingSchool of StomatologyJilin UniversityChangchun130021China Department of Chemistry Korea UniversitySeoul02841Korea National Key Laboratory of Green Pesticide International Joint Research Center for Intelligent Biosensor Technology and HealthCollege of ChemistryCentral China Normal UniversityWuhan430079China

Currently,the escalating crisis of bacterial infections and antibiotic resistance poses a significant global public health challenge[1-3].This situation has driven the search for novel antimicrobial ***,a crucial micr... 详细信息

关键词： metabolism resistance balance

Piezotronic neuromorphic devices:principle,manufacture,and applications

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International Journal of Extreme Manufacturing 2024年第3期6卷 363-385页

作者： Xiangde Lin Zhenyu Feng Yao Xiong Wenwen sun Wanchen Yao Yichen Wei Zhong Lin Wang Qijun sun Department of Research Shanghai University of Medicine and Health Sciences Affiliated Zhoupu HospitalShanghai 201318People’s Republic of China Beijing Institute of Nanoenergy and Nanosystems Chinese Academy of SciencesBeijing 101400People’s Republic of China Center on Nanoenergy Research School of Chemistry and Chemical EngineeringGuangxi UniversityNanning 530004People’s Republic of China Shandong Zhongke Naneng Energy Technology Co. LtdDongying 257061People’s Republic of China Georgia Institute of Technology AtlantaGA 30332-0245United States of America

With the arrival of the era of artificial intelligence(AI)and big data,the explosive growth of data has raised higher demands on computer hardware and *** techniques inspired by biological nervous systems are expected to be one of the approaches to breaking the von Neumann *** neuromorphic devices modulate electrical transport characteristics by piezopotential and directly associate external mechanical motion with electrical output signals in an active manner,with the capability to sense/store/process information of external *** this review,we have presented the piezotronic neuromorphic devices(which are classified into strain-gated piezotronic transistors and piezoelectric nanogenerator-gated field effect transistors based on device structure)and discussed their operating mechanisms and related manufacture ***,we summarized the research progress of piezotronic neuromorphic devices in recent years and provided a detailed discussion on multifunctional applications,including bionic sensing,information storage,logic computing,and electrical/optical artificial ***,in the context of future development,challenges,and perspectives,we have discussed how to modulate novel neuromorphic devices with piezotronic effects more *** is believed that the piezotronic neuromorphic devices have great potential for the next generation of interactive sensation/memory/computation to facilitate the development of the Internet of Things,AI,biomedical engineering,etc.

关键词： piezotronics neuromorphic devices strain-gated transistors piezoelectric nanogenerators synaptic transistors