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Effect of Jiuwei Zhuhuang Powder on Cough Resolution in Children with Upper Respiratory Tract Infections:A Multicenter Randomized Controlled Trial

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Chinese Journal of Integrative Medicine 2022年第5期28卷 387-393页

作者： LUO Hui SONG Gui-Hua MA Xiao-jian sun meng-meng ZHANG Man XIE Jian-rong PENG Shao Institute for Tibetan Medicine China Tibetology Research CenterBeijing(100101)China Department of Pediatrics the First Affiliated Hospital of Henan University of Chinese MedicineZhengzhou(450000)China Department of Pediatrics Huaihe Hospital of Henan UniversityZhengzhou(450000)China Department of Pediatrics the First Affiliated Hospital of Zhengzhou UniversityZhengzhou(475000)China School of Statistics Renmin University of ChinaBeijing(100872)China

Objective:To assess the effectiveness of Jiuwei Zhuhuang Powder(JWZH),a Tibetan patent medicine in treating upper respiratory tract infection(URTI)associated cough in children.Methods:The study was a multicenter,randomized,open-label,controlled trial.A total of 142 children aged 2 to 14 years old,with URTIassociated cough within 48 h of onset,were randomly assigned to two groups at a 1:1 ratio by computer-generated randomization sequence.Children were treated with JWZH(1 to 1.5 g,twice to thrice daily)in the treatment group or conventional treatment(Pediatric Paracetamol,Artificial Cow-bezoar and Chlorphenamine Maleate Granules,0.25 to 1 g,thrice daily)in the control group for 5 days.The primary endpoints were the time to cough resolution and 4-day cough resolution rate.The secondary endpoints were the daily improvement in symptom scores and cough resolution rate during the study period.Results:A total of 138 children were included in the intention-to-treat analysis,with 71 cases in the treatment group and 67 cases in the control group.Compared with the conventional treatment,the children receiving JWZH had a shorter time to cough resolution[hazard ratio,2.10;95%confidence interval(CI),1.29-3.40;P=0.003].The median time to cough resolution for children receiving JWZH was shorter than that of the conventional treatment(2 days vs.3 days;P0.05).Adverse events was reported in 5.6%(4/71)and 4.5%(3/67)in participants of JWZH and PPACCM groups(P>0.05),respectively,which were all mild and resolved without treatment.Conclusion:JWZH seemed to be a safe and effective therapy for URTI-associated cough in children.(Trial registration No.Chi CTR2000039421)

关键词： child cough upper respiratory tract infection Jiuwei Zhuhuang Powder randomized controlled trial Tibetan medicine

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可持续生计视角下脱贫户返贫风险评估及防控——以新疆维吾尔自治区和田地区C县为例

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湖北农业科学 2024年第7期63卷 224-230页

作者：姚昊彤张晔孙萌萌新疆农业大学公共管理学院乌鲁木齐830052

以新疆维吾尔自治区和田地区C县为研究区域,综合运用问卷调查、层次分析法、熵权法、模糊综合评价对返贫风险进行评估。结果表明,C县人力资本、自然资本、物质资本、金融资本和社会资本返贫风险的评价值分别为2.784 4、1.965 5、2.540 5... 详细信息

以新疆维吾尔自治区和田地区C县为研究区域,综合运用问卷调查、层次分析法、熵权法、模糊综合评价对返贫风险进行评估。结果表明,C县人力资本、自然资本、物质资本、金融资本和社会资本返贫风险的评价值分别为2.784 4、1.965 5、2.540 5、3.559 0、1.861 2,人力资本、物质资本和金融资本风险是造成脱贫户返贫的主要风险;脱贫户的返贫风险等级为中等风险,返贫风险的综合评价值为2.588 3;研究发现,C县存在人力资本存量不足、主导产业发展不成熟、土地流转难度较大、基层组织发挥作用不充分、帮扶责任人的管理不够精准、帮扶工作的专业化和多样化有待提升、脱贫户社会融入不足、返贫监测预警工作不完善等问题;针对以上问题,提出一是提升内生动力,促进人力资本积累;二是加强产业规划,提升产业后续帮扶力;三是强化基层组织引领,引导发挥先锋作用;四是提升乡村治理水平,帮助农户融入社会;五是落实预警机制,完善返贫监测系统。

关键词：可持续生计返贫风险脱贫户熵权法和田地区新疆维吾尔自治区

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DRGs付费背景下不稳定型心绞痛药物治疗成效分析

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中国处方药 2024年第6期22卷 72-75页

作者：孙蒙蒙李新柴微波王虹天津市北辰医院药剂科天津300400

目的分析按病种分组(DRGs)付费背景下不稳定型心绞痛药物治疗成效。方法选择2020年11月~2022年10月期间收治的不稳定型心绞痛治疗病例进行回顾性分析,总例数600例,根据是否实施DRGs付费模式,将数据分为常规组(2020年11月~2021年10月,300... 详细信息

目的分析按病种分组(DRGs)付费背景下不稳定型心绞痛药物治疗成效。方法选择2020年11月~2022年10月期间收治的不稳定型心绞痛治疗病例进行回顾性分析,总例数600例,根据是否实施DRGs付费模式,将数据分为常规组(2020年11月~2021年10月,300例)与研究组(2021年11月~2022年10月,300例)。常规组按照临床用药常规模式给药,研究组基于DRGs付费背景开展药物治疗。比较两组症状消失时间、胸痛持续时间、药品费用、住院总费用等指标;比较治疗效果及不合理用药发生率。结果与常规组相比,研究组胸痛、呼吸困难、心悸等症状消失时间、单次胸痛平均持续时间、住院时间更短(P<0.05);研究组药品费用、住院总费用更低(P<0.05),研究组药占比更低(P<0.05);与常规组相比,研究组治疗总有效率更高(P<0.05);与常规组相比,研究组发生过量用药、重复用药、用法错误、药品选择错误、处方制定错误等不合理用药占比更低(P<0.05)。结论DRGs付费背景下确定不稳定型心绞痛治疗药物并予以对症治疗,可迅速改善患者临床症状,显著提升治疗成效,还可降低不合理用药发生概率,进而降低药品费用与住院总费用,减轻患者经济负担。

关键词： DRGs付费不稳定型心绞痛治疗药物成效

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高压氧辅助早期康复干预对腹腔镜腰大池腹腔分流术治疗的颅脑损伤并脑积水患者神经功能恢复的作用

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罕少疾病杂志 2024年第4期31卷 34-36页

作者：孙萌萌张鸿日刘洪峰河南省南阳医专第一附属医院门诊部河南南阳473000

目的探讨高压氧辅助早期康复干预对腹腔镜腰大池腹腔分流术治疗的颅脑损伤并脑积水患者神经功能恢复的作用。方法本研究共纳入150例颅脑损伤并脑积水患者,所有病例均来源于河南省南阳医专第一附属医院,选取时间为2021年3月至2023年3月,... 详细信息

目的探讨高压氧辅助早期康复干预对腹腔镜腰大池腹腔分流术治疗的颅脑损伤并脑积水患者神经功能恢复的作用。方法本研究共纳入150例颅脑损伤并脑积水患者,所有病例均来源于河南省南阳医专第一附属医院,选取时间为2021年3月至2023年3月,进行回顾性分析,按照护理干预方法的不同分为对照组(75例,给予常规护理干预)和研究组(75例,在常规护理干预的基础上联合早期康复干预措施)。所有患者均接受高压氧辅助腹腔镜腰大池腹腔分流术治疗。将两组患者护理前后神经功能评分、运动功能评分、脑组织损伤,以及生活质量评分进行对比。结果护理后两组患者NIHSS评分均相较于护理前下降,且研究组患者相较于对照组下降,而两组患者FMA评分均相较于护理前上升,且研究组患者上述评分相较于对照组上升(均P0.05);护理后两组患者生理功能、生理职能、躯体疼痛等各项生活质量评分均相较于护理前上升,且研究组患者上述评分均相较于对照组上升(均P<0.05)。结论高压氧辅助早期康复干预应用于腹腔镜腰大池腹腔分流术治疗的颅脑损伤并脑积水患者中,可使血清NSE、S100β指标水平下降,有助于患者神经功能的改善,并促进肢体运动的改善,提升生活质量,临床价值较高。

关键词：高压氧早期康复干预腹腔镜腰大池腹腔分流术颅脑损伤脑积水神经功能

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Natural marmatite photocatalyst for treatment of mineral processing wastewater to help zero wastewater discharge

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Journal of Environmental Sciences 2024年第8期142卷 83-91页

作者： Meirong Wu Wei sun Xiangsong meng Jianhua Kang Yue Yang School of Minerals Processing and Bioengineering Central South UniversityChangsha 410083China Key Laboratory of Hunan Province for Clean and Efficient Utilization of Strategic Calcium-containing Mineral Resources Central South UniversityChangsha 410083China

Mineral processing wastewater(MPW)with large discharge and high toxicity affects environmental safety,and the realizing zero discharge of MPW is of great significance for reducing environmental pollution,saving water resources,and promoting the sustainable development of the mining industry.In this study,we reported natural marmatite(NM)as a low-cost and efficient photocatalyst for the treatment of MPW to help zero wastewater discharge.The photocatalytic activity of NM was evaluated by the removal of total organic carbon(TOC)from MPW under visible-light illumination,and the optimal degradation conditions were discussed.Results showed that superoxide free radicals(^(·)O_(2)^(-))were the dominant active species responsible for organic pollutants degradation,and 74.25%TOC removal was obtained after 120 min reaction under the optimum treatment conditions.Meanwhile,the wastewater treated by NM photocatalysis can be reused in the flotation system without adverse impact on the product index.Based on these findings,a model of zero wastewater discharge for flotation with the help of photocatalytic treatment was established,it indicated that the water of the whole system can be balanced without affecting the ore dressing index,which showed that visible light-driven photocatalyst has a promising application prospect in the treatment and recycling of industrial wastewater.

关键词： Natural mineral Photocatalysis Industrial wastewater Wastewater recycling Water balance

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Optimizing circumferential assembly angle of rotor parts connected by curvic couplings based on acquired tooth surface error data

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Chinese Journal of Aeronautics 2024年第3期37卷 404-416页

作者： Huibin sun meng LIU Yingzhi ZHANG Chenle WEI Key Laboratory of High Performance Manufacturing for Aero Engine Ministry of Industry and Information TechnologyNorthwestern Polytechnical UniversityXi’an 710072China AECC South Industry Company Limited Zhuzhou 412002China

Due to the excellent self-centering and load-carrying capability,curvic couplings have been widely used in advanced aero-engine rotors.However,curvic tooth surface errors lead to poor assembly precision.Traditional physical-master-gauge-based indirect tooth surface error measurement and circumferential assembly angle optimization methods have the disadvantages of high cost and weak generality.The unknown tooth surface fitting mechanism is a big barrier to assembly precision prediction and improvement.Therefore,this work puts forward a data-driven assembly simulation and optimization approach for aero-engine rotors connected by curvic couplings.The origin of curvic tooth surface error is deeply investigated.Using 5-axis sweep scan method,a large amount of high-precision curvic tooth surface data are acquired efficiently.Based on geometric models of parts,the fitting mechanism of curvic couplings is uncovered for assembly precision simulation and prediction.A circumferential assembly angle optimization model is developed to decrease axial and radial assembly runouts.Experimental results show that the assembly precision can be predicted accurately and improved dramatically.By uncovering the essential principle of the assembly precision formation and proposing circumferential assembly angle optimization model,this work is meaningful for assembly quality,efficiency and economy improvement of multistage aero-engine rotors connected by curvic couplings.

关键词： Curvic couplings Tooth surface error Assembly precision Axial and radial runouts Circumferential assembly angle

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Gut microbiota and female health

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World Journal of Gastroenterology 2024年第12期30卷 1655-1662页

作者： meng-Yao Wang Li-Xuan Sang Si-Yu sun Department of Gastroenterology Shengjing Hospital of China Medical UniversityShenyang 110022Liaoning ProvinceChina Department of Gastroenterology Endoscopic CenterEngineering Research Center of Ministry of Education for Minimally Invasive Gastrointestinal Endoscopic TechniquesShengjing Hospital of China Medical UniversityShenyang 110004Liaoning ProvinceChina

The gut microbiota is recognized as an endocrine organ with the capacity to influence distant organs and associated biological pathways.Recent advan-cements underscore the critical role of gut microbial homeostasis in female health;with dysbiosis potentially leading to diseases among women such as polycystic ovarian syndrome,endometriosis,breast cancer,cervical cancer,and ovarian cancer etc.Despite this,there has been limited discussion on the underlying mechanisms.This editorial explores the three potential mechanisms through which gut microbiota dysbiosis may impact the development of diseases among women,namely,the immune system,the gut microbiota-estrogen axis,and the metabolite pathway.We focused on approaches for treating diseases in women by addressing gut microbiota imbalances through probiotics,prebiotics supple-mentation,and fecal microbiota transplantation(FMT).Future studies should focus on determining the molecular mechanisms underlying associations between dysbiosis of gut microbiota and female diseases to realize precision medicine,with FMT emerging as a promising intervention.

关键词： Gut microbiota Female health Estrogen Polycystic ovarian syndrome Endometriosis

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Experimental study on the variation of optical remote sensing imaging characteristics of internal solitary waves with wind speed

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Journal of Oceanology and Limnology 2024年第2期42卷 408-420页

作者： Zhe CHANG Lina sun Tengfei LIU meng ZHANG Keda LIANG Junmin meng Jing WANG School of Physics and Optoelectronic Engineering Ocean University of ChinaQingdao 266100China First Institute of Oceanography Ministry of Natural ResourcesQingdao 266061China Technology Innovation Center for Ocean Telemetry Ministry of Natural ResourcesQingdao 266061China

Optical remote sensing has been widely used to study internal solitary waves(ISWs).Wind speed has an important effect on ISW imaging of optical remote sensing.The light and dark bands of ISWs cannot be observed by optical remote sensing when the wind is too strong.The relationship between the characteristics of ISWs bands in optical remote sensing images and the wind speed is still unclear.The influence of wind speeds on the characteristics of the ISWs bands is investigated based on the physical simulation experiments with the wind speeds of 1.6,3.1,3.5,3.8,and 3.9 m/s.The experimental results show that when the wind speed is 3.9 m/s,the ISWs bands cannot be observed in optical remote sensing images with the stratification of h_(1)∶h_(2)=7∶58,ρ_(1)∶ρ_(2)=1∶1.04.When the wind speeds are 3.1,3.5,and 3.8 m/s,which is lower than 3.9 m/s,the ISWs bands can be obtained in the simulated optical remote sensing image.The location of the band’s dark and light extremum and the band’s peak-to-peak spacing are almost not affected by wind speed.More-significant wind speeds can cause a greater gray difference of the light-dark bands.This provided a scientific basis for further understanding of ISW optical remote sensing imaging.

关键词： internal solitary wave(ISW) optical remote sensing wind speed characteristics of ISWs bands

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Aeroengine thrust estimation and embedded verification based on improved temporal convolutional network

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Chinese Journal of Aeronautics 2024年第1期37卷 106-117页

作者： Wanzhi meng Zhuorui PAN Sixin WEN Pan QIN Ximing sun Key Laboratory of Intelligent Control and Optimization for Industrial Equipment of Ministry of Education Dalian University of TechnologyDalian 116024China School of Control Science and Engineering Dalian University of TechnologyDalian 116024China

Thrust estimation is a significant part of aeroengine thrust control systems.The traditional estimation methods are either low in accuracy or large in computation.To further improve the estimation effect,a thrust estimator based on Multi-layer Residual Temporal Convolutional Network(M-RTCN)is proposed.To solve the problem of dead Rectified Linear Unit(ReLU),the proposed method uses the Gaussian Error Linear Unit(GELU)activation function instead of ReLU in residual block.Then the overall architecture of the multi-layer convolutional network is adjusted by using residual connections,so that the network thrust estimation effect and memory consumption are further improved.Moreover,the comparison with seven other methods shows that the proposed method has the advantages of higher estimation accuracy and faster convergence speed.Furthermore,six neural network models are deployed in the embedded controller of the micro-turbojet engine.The Hardware-in-the-Loop(HIL)testing results demonstrate the superiority of M-RTCN in terms of estimation accuracy,memory occupation and running time.Finally,an ignition verification is conducted to confirm the expected thrust estimation and real-time performance.

关键词： Thrust estimation Temporal convolutional network Embedded deployment Hardware-in-the-loop testing Ignition verification

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Advances and challenges in artificial intelligence text generation

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Frontiers of Information Technology & Electronic Engineering 2024年第1期25卷 64-83页

作者： Bing LI Peng YANG Yuankang sun Zhongjian HU meng YI School of Computer Science and Engineering Southeast UniversityNanjing 210000China Key Laboratory of Computer Network and Information Integration Ministry of EducationSoutheast UniversityNanjing 210000China

Text generation is an essential research area in artificial intelligence(AI)technology and natural language processing and provides key technical support for the rapid development of AI-generated content(AIGC).It is based on technologies such as natural language processing,machine learning,and deep learning,which enable learning language rules through training models to automatically generate text that meets grammatical and semantic requirements.In this paper,we sort and systematically summarize the main research progress in text generation and review recent text generation papers,focusing on presenting a detailed understanding of the technical models.In addition,several typical text generation application systems are presented.Finally,we address some challenges and future directions in AI text generation.We conclude that improving the quality,quantity,interactivity,and adaptability of generated text can help fundamentally advance AI text generation development.

关键词： AI text generation Natural language processing Machine learning Deep learning

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