检索结果-南通市图书馆

Chemical Research in Chinese Universities 2022年第4期38卷 1005-1011页

作者： sun bolun CHAO Danming WANG Ce Alan G.MacDiarmid Institute Jilin UniversityChangchun130012P.R.China

Nanogenerators,as the typical conversion of mechanical energy to electrical energy devices,have great potential in the application of providing sustainable energy sources for powering miniature *** this work,cellulose acetate/cellulose nanocrystal(CA/CNC)composite nanofiber membranes were prepared by electrospinning method and then utilized to manufacture a flexible pressure-driven *** addition of CNC not only increased the content of piezoelectric cellulose I crystallization but also strengthened the mechanical deformation of the nanofiber membranes,which could greatly enhance the piezoelectric performance of CA/CNC composite *** CA/CNC composite nanofiber membrane with 20%(mass fraction)of CNC(CA/CNC-20%)showed optimal piezoelectric conversion performance with the output voltage of 1.2 V under the force of 5 N(frequency of 2 Hz).Furthermore,the output voltage of the CA/CNC-20%nanogenerator device exhibited a linear relationship with applied impact force,indicating the great potential in pressure sensors.

关键词： Piezoelectric Nanogenerator Electrospinning Cellulose acetate Nanocellulose crystal

Preparation of Molecularly Imprinted Sericin/ Poly（vinyl alcohol） Electrospun Fibers for Selective Removal of Methylene Blue

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chemical Research in Chinese Universities 2017年第6期33卷 986-994页

作者： ZHAO Rui LI Xiang sun bolun LI Yumei LI Yanzi WANG Ce Alan G. MacDiarmid lnstitute College of Chemistry Jilin University Changchun 130012 P. R. China

Sericin（SS）, as an abtmdant and renewable resource in nature, has been proven to be a good adsorbent for metal ions or organic dyes removal. In this study, glutaraldehyde vapor cross-linked sericin-based electrospun fiber adsorbent was developed for the removal of methylene blue（MB） from wastewater. To overcome the problem of decreasing adsorption capacity by excessive functional group cross-linking, MB-imprinted sericin/poly（vinyl alcohol）（PVA） electrospun fiber adsorbent was prepared. Biocompatible PVA was added to the electrospinning solution to improve the spinnability and mechanical property. Scanning electron microscopy（SEM）, Fourier transforms infrared spectroscopy（FTlR）, and so forth were used to confirm their structures and composition. The adsorption performance toward the template molecule MB, including pH effect, adsorption isotherm, adsorption kinetics, adsorption selectivity, and reusability, was investigated. By comparison with non-imprinted sericin/PVA electrospun fibers, MB-imprinted sericin/PVA electrospun fiber adsorbent showed an enhanced and selective adsorption capacity toward MB with a good regeneration and recycling ability. The adsorption test suggests that the resulting MB-imprinted sericin/PVA electrospun fibers are promising adsorbents for MB removal from aqueous system.

关键词： Sericin Molecular imprinting Electrosptun fiber Adsorbent Methylene blue

Polyphenols Extracted from Enteromorpha clathrata Induce Apoptosis in Hepa1-6 Cell by Activating the Mitochondrial Apoptosis Signaling Pathways

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Ocean University of China 2023年第5期22卷 1393-1402页

作者： ZHANG Panxue sun bolun TONG Jingjing XIA Geran ZHANG Jinjie LI Chao YANG Wenge College of Food and Pharmaceutical Sciences Ningbo UniversityNingbo 315211China Key Laboratory of Animal Protein Food Deep Processing Technology of Zhejiang Province Ningbo UniversityNingbo 315211China

Green alga Enteromorpha clathrata(***)contains a variety of bioactive compounds,including polysaccharides,polyphenols and fat-soluble pigments etc.,among which polyphenols exhibit a wide range of medicinal *** polyphenols(ECPs)have shown various biological activities such as antioxidant,anti-inflammatory and antidiabetic effects;however,the potential of ECPs as an anti-cancer reagent remains *** aim of this study was to investigate the anti-tumor activity and underlying mechanisms of ECPs on hepatocellular *** cytotoxicity of Hepa1-6 cells was determined by 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide(MTT)and lactate dehydrogenase(LDH)*** cytometry and fluorescence microscope analysis of cell apoptosis after annexin V-fluorescein isothiocyanate(FITC)/propidium iodide(PI)staining.2',7'-dichlorodihydrofluorescein diacetate(DCFH-DA)assay was used for intracellular reactive oxygen species(ROS)***-9 activity was determined using cspase-9 colorimetric *** transmembrane potential(Δψm)was measured using *** blot and quantitative real-time PCR(qPCR)were used to assess the expressions of the apoptosis regulators Bax,Bcl-2,cytochrome c and *** was found that ECPs showed a dose-dependent cytotoxicity against Hepa1-6 cells by inducing *** apoptosis in ECPs-treated Hepa1-6 cells was accompanied by the loss of mitochondrial membrane potential,elevated ROS generation,increased release of mitochondrial cytochrome c,and up-regulation of caspase-9 and *** expressions of Bax(pro-apoptotic molecule)and Bcl-2(apoptosis suppressor)were up-regulated and down-regulated,respectively,at both mRNA and protein *** molecular alterations revealed that ECPs caused apoptosis of cells through the mitochondrial pathway,suggesting that ECPs are potential candidates to be developed for liver cancer treatment.

关键词： Enteromorpha clathrate polyphenol anti-cancer activity apoptosis mitochondrial-dependent pathway

Effect of Glycosylation on the Physicochemical Properties,Structure and Iron Bioavailability of Ferritin Extracted from Tegillarca granosa

在线全文

学校读者我要写书评

暂无评论

Journal of Ocean University of China 2023年第4期22卷 1068-1078页

作者： sun bolun TAN Beibei LI Gaoshang YANG Changjie ZHANG Panxue LI Chao YANG Wenge College of Food and Pharmaceutical Sciences Ningbo UniversityNingbo 315211China College of Biosystem Engineering and Food Science Zhejiang UniversityHangzhou 310058China Key Laboratory of Animal Protein Food Deep Processing Technology of Zhejiang Province Ningbo UniversityNingbo 315211China

Iron deficiency anemia(IDA)is a major global health *** granosa has been considered as an excellent source of iron given its high content of iron-binding protein,*** aim of the present study was to determine the physicochemical properties,protein structures,and iron uptake of ferritin extracted from ***,and to evaluate the potential impacts of chitosan glycosylation on these *** on Box-Behnken design and response surface methodology,the optimal conditions for glycosylation included a ferritin/chitosan mass ratio of 4:1,a pH of 5.5,a reaction time of 10 min,and a reaction temperature of 50℃.Glycosylation caused decreased surface hydrophobicity and elevated water-holding capacity of ferritin due to the introduction of hydrophilic ***,glycosylation improved antioxidant capacity of ferritin by 20.69%–189.66%,likely owing to the protons donated by saccharide moiety to terminate free radical chain *** in vitro digestibility of ferritin was elevated by 22.56%–104.85%after glycosylation,which could be associated with lessβ-sheet content in secondary structure that made the glycosylated protein less resistant to enzymatic *** results of the iron bioavailability in Caco-2 cells revealed that ferritin(78.85–231.77 ngmg^(−1))exhibited better iron bioavailability than FeSO4(51.48–114.37 ngmg^(−1))and the values were further elevated by glycosylation with chitosan(296.23–358.20 ngmg^(−1)),which may be related to the physicochemical properties of ferritin via glycosylation *** results provide a basis for the development of *** derived ferritin and its glycosylated products,and can promote the utilization of aquatic resources.

关键词： ferritin Tegillarca granosa glycosylation box-behnken design iron bioavailability physicochemical properties

维普期刊数据库博看期刊

在线全文

学校读者我要写书评

暂无评论

暖通空调安装施工技术应用解析

山西建筑 2017年第17期43卷 115-116页

作者：孙博伦山东华新房地产开发有限公司山东泰安271000

分析了暖通空调安装施工中存在的问题,从完善暖通空调系统的管线安装、解决空调结露滴水问题、处理空调运行时的噪声等方面,提出了具体的解决措施,为同类工程提供参考。

关键词：暖通空调安装技术噪声居住环境

在线全文

学校读者我要写书评

暂无评论

人工智能与经济发展探究

无线互联科技 2021年第2期18卷 86-87页

作者：孙博伦陕西服装工程学院陕西西安712046

人工智能经过50多年的发展,已经从最开始的理论研究走向了市场,对社会、经济、科技的发展产生了极大的推动作用,人工智能应用于经济发展已然成为21世纪的核心。文章主要围绕人工智能与经济发展、劳动就业、国际分工展开,探讨人工智能在... 详细信息

人工智能经过50多年的发展,已经从最开始的理论研究走向了市场,对社会、经济、科技的发展产生了极大的推动作用,人工智能应用于经济发展已然成为21世纪的核心。文章主要围绕人工智能与经济发展、劳动就业、国际分工展开,探讨人工智能在时代发展下的价值体现。

关键词：人工智能经济发展价值

基于POD-PCE-Kriging模型的航空发动机高维多目标优化

在线全文

学校读者我要写书评

暂无评论

航空动力学报 2023年第7期38卷 1604-1614页

作者：马跃郭明明孙博伦田野宋文艳乐嘉陵西南科技大学信息工程学院四川绵阳621010 中国空气动力研究与发展中心高超声速冲压发动机技术重点实验室四川绵阳621000 西北工业大学动力与能源学院西安710129

针对于传统的航空发动机燃烧室设计过程计算周期长,加工和试验成本高,制约发动机设计周期的问题,基于航空发动机燃烧室模型,结合POD-PCE-Kriging(本征正交分解-多项式混沌展开-Kriging)模型和粒子群优化(PSO)算法开展了燃烧性能代理模... 详细信息

针对于传统的航空发动机燃烧室设计过程计算周期长,加工和试验成本高,制约发动机设计周期的问题,基于航空发动机燃烧室模型,结合POD-PCE-Kriging(本征正交分解-多项式混沌展开-Kriging)模型和粒子群优化(PSO)算法开展了燃烧性能代理模型的构建和多目标优化设计。通过试验,应用POD-PCE-Kriging模型预测结果与一维程序计算结果进行对比分析,针对于燃烧效率和总压损失预测值的方均根误差分别为0.006 3%和0.122 7%。对设计变量参数开展寻优,并对获取的Pareto最优解集进行了分析,为满足性能指标的先进航空发动机燃烧室设计提供了物理见解,可以快速准确获得满足最优性能的设计参数,缩短航空发动机的研制周期。

关键词：航空发动机燃烧室设计代理模型 POD-PCE-Kriging模型粒子群优化算法多目标优化

吉林省支援武汉抗疫的部分临床一线护士灾害准备度调查

在线全文

学校读者我要写书评

暂无评论

护理研究 2020年第6期34卷 938-940页

作者：鲍金雷孙博伦张卉王洋长春中医药大学吉林130117 吉林大学第一医院

[目的]了解吉林省支援武汉抗疫的临床一线护士的灾害准备度情况.[方法]选取吉林省支援武汉抗疫的60名临床一线护士作为研究对象,采用一般资料调查表和中文版灾害准备度评估量表进行调查.[结果]60名护士灾害准备度总得分为(157. 23± 39.... 详细信息

[目的]了解吉林省支援武汉抗疫的临床一线护士的灾害准备度情况.[方法]选取吉林省支援武汉抗疫的60名临床一线护士作为研究对象,采用一般资料调查表和中文版灾害准备度评估量表进行调查.[结果]60名护士灾害准备度总得分为(157. 23± 39. 12)分,文化程度、职称、科室、是否参加过灾害救援或相关培训是护士灾害准备度的影响因素(均P<0. 05).[结论]本次吉林省支援武汉抗疫的临床一线护士灾害准备度处于中等水平,文化程度较高、在重症监护室或急诊科工作、职称较高、参加过灾害救援或相关培训的护士灾害准备度较好.

关键词：新型冠状病毒肺炎吉林省临床护士灾害准备度调查

在线全文

学校读者我要写书评

暂无评论

河豚毒素的检测与制备方法研究进展

南方水产科学 2018年第3期14卷 126-132页

作者：李来好孙博伦赵东豪中国水产科学研究院南海水产研究所农业部水产品加工重点实验室广东省渔业生态环境重点开放实验室广东广州510300 浙江海洋大学浙江舟山316021

河豚毒素为一类自然界广泛分布的神经性毒素,毒性极强,可通过阻碍钠离子通道而抑制神经传导,使神经麻痹而导致死亡,成为威胁水产品质量安全的重要风险隐患之一,受到国际社会重点关注而被严格管控。同时,河豚毒素具有镇静、镇痛和麻醉等... 详细信息

河豚毒素为一类自然界广泛分布的神经性毒素,毒性极强,可通过阻碍钠离子通道而抑制神经传导,使神经麻痹而导致死亡,成为威胁水产品质量安全的重要风险隐患之一,受到国际社会重点关注而被严格管控。同时,河豚毒素具有镇静、镇痛和麻醉等药理作用,在临床医疗方面应用前景广泛。河豚毒素的检测方法主要有生物法、免疫法和仪器分析法等3大类。但由于缺乏高获得率、高分离度的纯化工艺和制备技术,难以大批量生产高纯度的河豚毒素,成为临床应用和安全管控的难点。文章概述了河豚毒素检测和制备方法的研究进展,并对各种方法的适用性及存在的问题进行了综述。

关键词：河豚毒素检测方法制备纯化

在线全文

学校读者我要写书评

暂无评论

人文护理在手术室护理中的应用效果观察

吉林医药学院学报 2019年第1期40卷 7-9页

作者：鲍金雷孙博伦曹阳孙淑清长春中医药大学护理学院吉林长春130117 长春中医药大学附属医院吉林长春130117

目的将人文护理应用到手术室的护理工作中,探讨人文护理的应用效果。方法将116例患者随机分为对照组和人文组两组。对照组患者采取常规护理方法,观察组患者在术前、术中和术后均进行人文护理干预。从患者手术过程中的配合度、手术前后... 详细信息

目的将人文护理应用到手术室的护理工作中,探讨人文护理的应用效果。方法将116例患者随机分为对照组和人文组两组。对照组患者采取常规护理方法,观察组患者在术前、术中和术后均进行人文护理干预。从患者手术过程中的配合度、手术前后心率的变化情况和心理情况对护理效果进行评价。结果人文组患者手术配合良好率高于对照组。在心率测量结果方面,人文组患者术前30 min和术后30 min测量结果均慢于对照组。在心理评分方面,人文组患者术前1 d和术后1 d评分结果均低于对照组。以上各项比较,差异有统计学意义(P <0. 05)。结论将人文护理应用于手术室的护理工作中,增加了患者术中的配合度,同时也有效缓解了患者的心理压力,护理效果显著。

关键词：手术室人文护理心理护理配合度