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A review of the safety and efficacy of current COVID-19 vaccines

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Frontiers of Medicine 2022年第1期16卷 39-55页

作者： Zehong Huang yingying su Tianying Zhang Ningshao Xia State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics National Institute of Diagnostics and Vaccine Development in Infectious DiseasesStrait Collaborative Innovation Center of Biomedicine and PharmaceuticsSchool of Public HealthXiamen UniversityXiamen 361102China

Vaccination is the most effective and feasible way to contain the coronavirus disease 2019(COVID-19)*** rapid development of effective COVID-19 vaccines is an extraordinary *** study reviewed the efficacy/effectiveness,immunogenicity,and safety profile of the 12 most progressed COVID-19 vaccines and discussed the challenges and prospects of the vaccine-based approaches in a global ***,most of the current vaccines have shown safety and efficacy/effectiveness during actual clinical trials or in the real-world studies,indicating a development of pandemic ***,many challenges are faced by pandemic control in terms of maximizing the effect of vaccines,such as rapid vaccine coverage,strategies to address variants with immune escape capability,and surveillance of vaccine safety in the medium-and long-terms.

关键词： COVID-19 SARS-CoV-2 vaccine safety efficacy effectiveness immunogenicity

Recent Advances in Graphitic Carbon Nitride-Based Chemiluminescence,Cataluminescence and Electrochemiluminescence

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Journal of Analysis and Testing 2017年第4期1卷 274-290页

作者： Hongjie Song Lichun Zhang yingying su Yi Lv College of Chemistry Sichuan UniversityChengdu 610064SichuanChina Analytical and Testing Center Sichuan UniversityChengdu 610064SichuanChina

Graphitic carbon nitride(g-C3N4)has attracted considerable attention due to its special structure and properties,such as its good chemical and thermal stability under ambient conditions,low cost and non-toxicity,and facile ***,g-C3N4-based sensors have been demonstrated to be of high interests in the areas of sensing due to the unique optical,electronic and catalytic properties of *** review focuses on the most salient advances in luminescent sensors based on g-C3N4,chemiluminescence,cataluminescence and electrochemiluminescence methods are *** review provides valuable information for researchers of related areas and thus may inspire the development of more practical and effective approaches for designing two-dimensional(2D)nanomaterial-assisted luminescent sensors.

关键词： Graphitic carbon nitride(g-C3N4) Chemiluminescence(CL) Cataluminescence(CTL) Electrochemiluminescence(ECL) Sensors

Sampled-data models and zero dynamics for nonlinear systems with relative degree two

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Sampled-data models and zero dynamics for nonlinear systems ...

Meta-analysis of the relationship between cytotoxin-associated gene-A and ischemic stroke subtypes

第25届中国控制与决策会议

作者： Cheng Zeng Shan Liang yingying su Yangsheng Li College of Automation Chongqing University Department of Mathematics Guiyang university Key Laboratory of Dependable Service Computing in Cyber Physical SocietyMinistry of Education Chongqing University Department of Electric and Electronic Information Engineering Chongqing University of Science and Technology

ISBN: (纸本)9781467355322

This paper derives a more accurate sampled-data model than the Yuz and Goodwin type model for nonlinear systems in the case of the relative degree two, and analyzes the sampling zero dynamics of the sampled-data model to show a condition which assures the stability of the sampling zero dynamics of the proposed model. It is a nature extension of Ishitobi et al.’s result from a single-input single-output （SISO） nonlinear systems to a multi-input multi-output （MIMO） nonlinear systems.

关键词： nonlinear systems sampled-data models zero dynamics relative degree

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Neural Regeneration Research 2011年第1期6卷 34-40页

作者： Xu Yang Xiaoli Zhao Yongjun Gao Zhidong Zheng Jilai Li Xinyi Li Xiaoyuan Niu yingying su Department of Neurology Aerospace Central Hospital (Aerospace Clinical Medical College of Peking University Peking University) Beijing100049 China Department of Neurology First Affiliated Hospital of Shanxi Medical University Taiyuan 030001 Shanxi Province China Department of Neurology Xuanwu Hospital of Capital Medical University Beijing 100053 China

OBJECTIVE： To assess the role of cytotoxin-associated gene-A （CagA） positive strains of Helicobacter pylori （Hp） in ischemic stroke （IS） subtypes. DATA SOURCES： A computer-based online search of PubMed, EMBASE, the Cochrane Collaboration database, the CNKI database and the VIP database, from January 1997 to July 2010, was performed to find relevant studies. DATA SELECTION： Case-control studies relevant to CagA with IS and IS subtypes were selected. Data regarding related factors in the case group and control group were acquired using the same approach. All patients had been diagnosed as exhibiting IS using skull CT or MRI, and were etiologically typed according to the 1993 TOAST diagnosis criteria. Two investigators independently performed the same search and study selection. Meta-analyses were then performed for the selected studies using RevMan 5.0 software （Cochrane Collaboration） after strict screening. Heterogeneity tests, sensitivity analyses and publication bias assessments were then conducted. MAIN OUTCOME MEAsuRES： Relationship of CagA with IS and IS subtypes. REsuLTS： Eight studies were selected, involving data from 879 patients with IS, and 849 healthy controls. Five out of eight of the selected studies were related to large artery atherosclerosis （461 patients with IS and 497 health controls）. The results of our meta-analysis revealed a significant association between prior infection with CagA-positive strains and increased risk of IS （odds ratio （OR） = 2.31,95% confidence interval （C/）： 1.89-2.82, P 〈 0.01）, In addition, we found an association between infection with CagA-negative strains and IS （OR = 0.57, 95%C1：0.47 0.70, P 〈 0.01）. CagA positive and negative strains were found to correlate with large artery atherosclerosis （CagA-positive strains： OR = 2.87, 95%C/： 2.19-3.77, P 〈 0.01; CagA-negative strains： OR = 0.51, 95%CL 0.39 0.67, P 〈 0.01）. Because of the diversity of etiological factors in the case-control study, we conducted further analyses a

关键词： ischemic stroke subtype helicobacterpylori cytotoxin-associated gene-A meta-analysis

Criteria and practical guidance for determination of brain death in children （BQCC version）

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Chinese Medical Journal 2014年第23期127卷 4140-4144页

作者： Qian suyun su yingying Department of Pediatric Intensive Care Unit Beijing Children's Hospital Capital Medical University Beijing100045 China Department of Neurology Xuanwu Hospital Capital Medical University Beijing 100053 China

Part I. Criteria for determination of brain death in children from 29 days to 18 yearsI. The prerequisites of the determinationA. Known cause of coma B. Exclusion of reversible coma.II. The clinical diagnosis A. Dee...

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Friendship Built on Sincerity Flourishing China-Malaysia educational and cultural exchange

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China Report ASEAN 2024年第6期9卷 56-59页

作者： su yingying the School of Asian Studies at BFsu the Centre for China-Malay Studies BFSU

“Bahasa jiwa bangasa”goes a Malay proverb,dubbing language the soul of a *** and cultural exchange serve not only as a bridge for closer friendship between peoples around the world but also as a driver to promote broader and deeper international cooperation in various *** understanding of language and culture is a prerequisite for people-to-people connectivity.

关键词： has exchange ish

Correlation between Helicobacter pylori infection and atherothrombotic stroke

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Neural Regeneration Research 2011年第5期6卷 391-395页

作者： Xu Yang Xiaoli Zhao Yongjun Gao Zhidong Zheng Jilai Li Jichen Du Xinyi Li XianhaoXu yingying su Department of Neurology Aerospace Central Hospital (Aerospace Clinical Medical College Affiliated to Peking University) Beijing 100049 China Department of Neurology First Affiliated Hospital of Shanxi Medical University Taiyuan 030001 Shanxi Province China Department of Neurology Xuanwu Hospital Affiliated to Capital Medical University Beijing 100053 China

Previous studies have demonstrated that Helicobacterpylori infection is associated with coronary atherosclerotic heart disease, but the correlation between Helicobacterpylori infection and ischemic stroke remains unclear. The present study assessed the effects of Helicobacter pylori infection on atherothrombotic stroke. This study included 115 individuals with atherothrombotic stroke, all of whom were patients receiving treatment at the Department of Neurology, Aerospace Central Hospital （Aerospace Clinical Medical College Affiliated to Peking University） in China, from March 2006 to July 2009. In addition, 131 controls without the history of cardiovascular disease, cerebrovascular disease or atherothrombosis were also enrolled in the study. Results show that the Helicobacterpylori-lgG positive rate was greater in the atherothrombotic stroke patients than in the controls, but the difference was not statistically significant （67.8% vs. 61.8%, OR = 1.301,95%C/： 0.769-2.203, P = 0.327）. After correction for potential risk factors for Helicobacter pylori infection and known risk factors for ischemic stroke, no significant difference was detected between them （OR = 1.278, 95%C1： 0.667-2.449, P = 0.459）. These results indicate that there is no specific correlation between Helicobacterpylori infection and atherothrombotic stroke. This finding requires further verification in large-sample prospective studies.

关键词： Helicobacter pylori atherothrombotic stroke risk factors

Historical tillage promotes grass-legume mixtures establishment and accelerates soil microbial activity and organic carbon decomposition

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Journal of Arid Land 2024年第7期16卷 910-924页

作者： ZHOU Jiqiong GONG Jinchao WANG Pengsen su yingying LI Xuxu LI Xiangjun LIU Lin BAI Yanfu MA Congyu WANG Wen HUANG Ting YAN Yanhong ZHANG Xinquan Department of Grassland Science College of Grassland Science&TechnologySichuan Agricultural UniversityChengdu 611130China Yunnan Sheep Breeding and Extension Center Kunming 655204China

Perennial grass-legume mixtures have been extensively used to restore degraded grasslands,increasing grassland productivity and forage *** is crucial for seedbed preparation and sustainable weed management for the establishment of grass-legume ***,a common concern is that intensive tillage may alter soil characteristics,leading to losses in soil organic carbon(SOC).We investigated the plant community composition,SOC,soil microbial biomass carbon(MBC),soil enzyme activities,and soil properties in long-term perennial grass-legume mixtures under two different tillage intensities(once and twice)as well as in a fenced grassland(FG).The establishment of grass-legume mixtures increased plant species diversity and plant community coverage,compared with *** with once tilled grassland(OTG),twice tilled grassland(TTG)enhanced the coverage of high-quality leguminous forage species by 380.3%.Grass-legume mixtures with historical tillage decreased SOC and dissolved organic carbon(DOC)concentrations,whereas soil MBC concentrations in OTG and TTG increased by 16.0%and 16.4%,respectively,compared with *** significantly decreased the activity of N-acetyl-β-D-glucosaminidase(NAG)by 72.3%,whereas soil enzymeβ-glucosidase(βG)in OTG and TTG increased by 55.9%and 27.3%,respectively,compared with *** analysis indicated a close association of the increase in MBC andβG activities with the rapid decline in *** result suggested that MBC was a key driving factor in soil carbon storage dynamics,potentially accelerating soil carbon cycling and facilitating biogeochemical *** establishment of grass-legume mixtures effectively improves forage quality and boosts plant diversity,thereby facilitating the restoration of degraded *** tillage assists in establishing legume-grass mixtures by controlling weeds,it accelerates microbial activity and organic carbon *** findings provide a foundation for understanding the

关键词： tillage grass-legume mixtures fencing grassland microbial biomass carbon β-glucosidase(βG) N-acetyl-β-D-glucosaminidase(NAG)

《中国成人脑死亡判断标准与操作规范(第二版)》解读

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中华医学杂志 2019年第17期99卷 1286-1287页

作者：宿英英首都医科大学宣武医院神经内科北京100053

脑死亡概念与判定标准已在全球多数国家达到共识。中国各界的认可度和认知度也越来越高。《中国成人脑死亡判定标准与操作规范(第二版)》保留了第一版的可操作性和可靠性特征,并对判定次数和前提条件进行了修订。希冀中国的脑死亡判定... 详细信息

脑死亡概念与判定标准已在全球多数国家达到共识。中国各界的认可度和认知度也越来越高。《中国成人脑死亡判定标准与操作规范(第二版)》保留了第一版的可操作性和可靠性特征,并对判定次数和前提条件进行了修订。希冀中国的脑死亡判定持续改进工作可促进医学和社会进步。

关键词：脑死亡判定标准