A review of the safety and efficacy of current COVID-19 vaccines

作     者：Zehong Huang Yingying Su Tianying Zhang Ningshao Xia Zehong Huang;Yingying Su;Tianying Zhang;Ningshao Xia

作者机构：State Key Laboratory of Molecular Vaccinology and Molecular DiagnosticsNational Institute of Diagnostics and Vaccine Development in Infectious DiseasesStrait Collaborative Innovation Center of Biomedicine and PharmaceuticsSchool of Public HealthXiamen UniversityXiamen 361102China 

出 版 物：《Frontiers of Medicine》 (医学前沿（英文版）)

年 卷 期：2022年第16卷第1期

页      面：39-55页

核心收录：

学科分类：1004[医学-公共卫生与预防医学(可授医学、理学学位)] 1002[医学-临床医学] 1001[医学-基础医学(可授医学、理学学位)] 100102[医学-免疫学] 100401[医学-流行病与卫生统计学] 10[医学] 

基　　金：supported by the National Natural Science Foundation of China(No.81991491) the Fujian Natural Science Foundation for Distinguished Young Scholars(No.2020J06007) the Bill and Melinda Gates Foundation(No.INV-005834) 

主　　题：COVID-19 SARS-CoV-2 vaccine safety efficacy effectiveness immunogenicity 

摘      要：Vaccination is the most effective and feasible way to contain the coronavirus disease 2019(COVID-19)*** rapid development of effective COVID-19 vaccines is an extraordinary *** study reviewed the efficacy/effectiveness,immunogenicity,and safety profile of the 12 most progressed COVID-19 vaccines and discussed the challenges and prospects of the vaccine-based approaches in a global ***,most of the current vaccines have shown safety and efficacy/effectiveness during actual clinical trials or in the real-world studies,indicating a development of pandemic ***,many challenges are faced by pandemic control in terms of maximizing the effect of vaccines,such as rapid vaccine coverage,strategies to address variants with immune escape capability,and surveillance of vaccine safety in the medium-and long-terms.