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Time-series gene expression prof iles in AGS cells stimulated with Helicobacter pylori

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World Journal of Gastroenterology 2010年第11期16卷 1385-1396页

作者： You, Yuan-Hai song, yan-yan Meng, Fan-Liang He, Li-Hua Zhang, Mao-Jun yan, Xiao-Mei Zhang, Jian-Zhong Chinese Ctr Dis Control & Prevent Natl Inst Communicable Dis Control & Prevent Beijing 102206 Peoples R China

AIM: To extend the knowledge of the dynamic interaction between Helicobacter pylori (H. pylori) and host mucosa. METHODS: A time-series cDNA microarray was performed in order to detect the temporal gene expression prof iles of human gastric epithelial adenocarcinoma cells infected with H. pylori. Six time points were selected to observe the changes in the model. A differential expression prof ile at each time point was obtained by comparing the microarray signal value with that of 0 h. Real-time polymerase chain reaction was subsequently performed to evaluate the data quality. RESULTS: We found a diversity of gene expression patterns at different time points and identifi ed a group of genes whose expression levels were significantly correlated with several important immune response and tumor related pathways. CONCLUSION: Early infection may trigger some important pathways and may impact the outcome of the infection.

关键词： Helicobacter pylori Gene expression Microarray Time-series

Ultra-flexible all-in-one anti-freeze photothermally enhanced supercapacitors

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Nano Research 2024年第8期17卷 7221-7229页

作者： Yongxin Lu Keke Li yan-yan song Zhida Gao Condense matter of physics College of ScienceNortheazistern UniversityShenyang 110004China

Wearable electronics powered by flexible energy storage devices have captured global *** low-temperature conditions,unfortunately,solidification of flexible hydrogel electrolyte and decreased pseudo-capacity of these devices largely hamper their practical *** this study,photothermally-active Prussian blue(PB)was introduced onto poly(3,4-ethylenedioxythiophene)/polyacrylamide(PEDOT/PAM)networks to address the challenges of electrolyte solidification and degraded pseudo-capacitance for flexible all-in-one device at low *** as-constructed PB/PEDOT/PAM hydrogel device delivers stable electrochemical performance and remarkable mechanical property with 1652%***,this hydrogel device well retains its flexibility in cold environment with a freezing point below−30℃.The incorporation of PB extends the voltage range to 1.5 V as a single device,thus significantly enhancing the electrochemical performance as an all-inone integrated *** from the outstanding photo-to-thermal conversion ability of embedded PB nanocubes,the temperature of the assembled all-in-one PB/PEDOT/PAM device increased from^(−2)0 to 17.7℃ after solar-light irradiation for only 5 ***,the degraded pseudo-capacitance was subsequently boosted to 287.1%of its original capacitance at−20℃.This study establishes a connection between flexible all-solid-state hydrogel devices and photothermally enhanced pseudocapacitors in freezing environments,thereby expanding the potential applications of multi-functional pseudo-capacitors.

关键词： all-in-one energy storage devices all-solid-state photothermal flexible low temperatures

Surgical treatment of right atrial myxoma and pulmonary embolism

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Chinese Medical Journal 2014年第1期127卷 187-188页

作者： Gu song Liu yan yan Jun Zhang Xitao Gao Jie Xin Yue Su Pixiong Department of Cardiac Surgery Beijing Chaoyang Hospital Capital Medical University Beijing 100020 China

Myxomas are rare benign tumours,with an estimated incidence of 0.5 per million of population per year.1It is most commonly of left atrial origin （75% to 90%）,less commonly right atrial （10% to 25%）,and rarely ventricular （1% to 4%）.2 Right atrial myomata generally presents as right heart failure,with signs of tricuspid valve *** association of pulmonary embolism with right atrial myxoma has been recognized at autopsy for many years.

关键词： cardiac surgery myxoma cardiac tumours pulmonary embolism

齿痛消炎灵颗粒联合牙周激光对牙周炎的应用效果及对口气和舌苔指标的影响

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现代生物医学进展 2024年第5期24卷 930-933,938页

作者：周家兴何娟谭俭琴宋燕燕彭于治贵州中医药大学第二附属医院口腔科贵州贵阳550001 贵州中医药大学第一附属医院口腔科贵州贵阳550001

目的:探讨齿痛消炎灵颗粒联合牙周激光对牙周炎的应用效果及对口气和舌苔指标的影响。方法:选取我院2020年7月到2023年7月收治的80例牙周炎患者,分为观察组与对照组,各40例。对照组采取常规治疗与口服齿痛消炎灵颗粒,观察组以对照组为基... 详细信息

目的:探讨齿痛消炎灵颗粒联合牙周激光对牙周炎的应用效果及对口气和舌苔指标的影响。方法:选取我院2020年7月到2023年7月收治的80例牙周炎患者,分为观察组与对照组,各40例。对照组采取常规治疗与口服齿痛消炎灵颗粒,观察组以对照组为基础,增加牙周激光治疗。对比两组患者临床疗效,对比其治疗前与治疗4周后菌斑指数(PLI),出血指数(BI)、探诊深度(PD)、临床附着丧失(CAL)相关牙周健康指标,口气感官值(OS)、口腔挥发硫化物(VSCs)相关口气指标以及舌苔厚度(Tt)、舌苔面积(Ta)相关舌苔指标变化。结果:观察组治疗总有效率较对照组高(P0.05),治疗后两组均降低,且与对照组相比,观察组较低(P0.05),治疗后两组均降低,且与对照组相比,观察组较低(P0.05),治疗后两组均降低,且观察组较对照组低(P<0.05)。结论:齿痛消炎灵颗粒联合牙周激光治疗牙周炎效果较好,改善患者牙周健康程度,减少舌苔情况,改善口气情况。

关键词：齿痛消炎灵颗粒牙周激光牙周炎牙周健康指标口气指标

Voltage-Controlled Scattering of Single Photons in a One-Dimensional Waveguide

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Chinese Physics Letters 2011年第7期28卷 148-151页

作者： LUO Ya-Qin song yan-yan GU Ling-Ming LANG Jia-Hong MA Xiao-San School of Electrical Engineering&Information Anhui University of TechnologyMaanshan 243002

We investigate theoretically the voltage-controlled single-photon transport properties in a one-dimensional *** transmission and reflection amplitudes are obtained by a full quantum-mechanical *** is revealed that one can control the single photon transmitted or reflected by adjusting the bias *** scheme may have applications in the design of optoelectronic devices.

关键词： Waveguide optoelectronic photon

Design,fabrication,and characterization of hierarchical mechanical metamaterials

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Frontiers of Mechanical Engineering 2024年第1期19卷 73-83页

作者： Jian song Junfei yan Bengang YI Automotive Engineering Research Institute BYD Auto Industry Co.Ltd.Shenzhen 518000China College of Civil and Transportation Engineering Shenzhen UniversityShenzhen 518060China

Natural mechanical materials,such as bamboo and bone,often exhibit superior specific mechanical properties due to their hierarchical porous *** the principle of hierarchy as inspiration can facilitate the development of hierarchical mechanical metamaterials(HMMs)across multiple length scales via 3D *** this work,we propose self-similar HMMs that combine octet-truss(OCT)architecture as the first and second orders,with cubic architecture as the third or more *** HMMs were fabricated using stereolithography 3D printing,with the length sizes ranging from approximately 200µm to the centimeter *** compressive stress–strain behaviors of HMMs exhibit a zigzag characteristic,and the toughness and energy absorption can be significantly enhanced by the hierarchical *** compressive moduli are comparable to that of natural materials,and the strengths are superior to that of most polymer/metal foams,alumina hollow/carbon lattices,and other natural ***,the flexural stress–strain curves exhibit a nonlinear behavior,which can be attributed to the hierarchical architecture and local damage *** relatively high mechanical properties can be attributed to the synergistic effect of the stretch-dominated OCT architecture and the bending-dominated cube ***,an ultralight HMM-integrated unmanned aerial vehicle(HMM-UAV)was successfully designed and *** HMM-UAV is~85%lighter than its bulk counterpart,remarkably extending the flight duration time(~53%).This work not only provides an effective design strategy for HMMs but also further expands the application benchmark of HMMs.

关键词： 3D printing mechanical metamaterials hierarchical architecture mechanical behavior unmanned aerial vehicle(UAV)

Antimicrobial Susceptibility of Streptococcus sp. to Quinupristin-dalfopristin in China

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Biomedical and Environmental Sciences 2014年第5期27卷 388-390页

作者： YOU Yuan Hai WANG Hai Bin TAO Xiao Xia song yan yan MENG Fan Liang yan Xiao Mei LUO Feng Ji ZHANG Jian Zhong State Key Laboratory for Infectious Disease Prevention and Control National Institute for Communicable Disease Control and Prevention Chinese Center for Disease Control and Prevention Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases Laboratory of Microbiology Chaoyang District Center for Disease Control and Prevention Beijing

This study aimed to determine the in vitro activity of quinupristin-alfopristin against Streptococcus sp. isolated in China. This agent is not yet available for clinical use, but it has been tested against a high proportion of resistant Staphylococcus oureus strains. A total of 156 streptococcal isolates, which were recovered from various geographic areas and diseases, were tested using the Etest （AB Biodisk, Solna, Sweden）. Quinupristin-alfopristin showed excellent activity against all of the tested streptococci isolates. These results provide useful data for the clinical use of quinupristin-alfopristin in China.

关键词： to Quinupristin-dalfopristin in China Antimicrobial Susceptibility of Streptococcus sp

Effect of nano-carbon black content on wetting phenomenon of molten steel and alumina-carbon ceramic filter substrates

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Journal of Iron and Steel Research International 2024年第8期31卷 1900-1913页

作者： Jin-wen song Wen yan Zhe Chen Ying Liu Shao-song Hong The State Key Laboratory of Refractories and Metallurgy Wuhan University of Science and TechnologyWuhan 430081HubeiChina National-provincial Joint Engineering Research Center of High Temperature Materials and Lining Technology Wuhan University of Science and TechnologyWuhan 430081HubeiChina Jiangsu Sheng Nai New Materials Co. Ltd.Taizhou 225503JiangsuChina

The effect of nano-carbon black content(O,8 and 12 wt.%)on the wettability of molten steel on Al_(2)O_(3)-C substrates was investigated by the sessile drop wetting method at 1500℃ under argon *** the beginning of the wetting experiment,the contact angle decreased with the increase in nano-carbon black *** the wetting experiment progressed,FeAl_(2)0_(4) layer and sheet Al_(2)O_(3) layer were found at the interface between the molten steel and the Al_(2)O_(3)-C substrates with O and 8 wt.% nano-carbon black content,and the contact angle deceased with *** the content of nano-carbon black was 12 wt.%,a large number of nano-Al_(2)O_(3) whiskers were observed,which made the contact angle between the molten steel and Al_(2)O_(3)-C substrate become *** on the scanning electron microscope and energy dispersive spectrometry results,the formation mechanism of FeAl2O4 layer and Al_(2)O_(3) layer and the interfacial reaction mechanism were proposed.

关键词： Contact angle Nano-carbon black Al_(2)O_(3)-C substrate Molten steel Interfacial reaction

Genome-wide SNP markers provided insights into the reproductive strategy and genetic diversity of the green tide causative species Ulva prolifera in China

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Journal of Oceanology and Limnology 2024年第2期42卷 533-543页

作者： song SUN Weiwei MA Nan WANG song FENG yan SUN CAS Key Laboratory of Marine Ecology and Environmental Sciences Institute of OceanologyChinese Academy of SciencesQingdao 266071China Laboratory for Marine Ecology and Environmental Science Laoshan LaboratoryQingdao 266237China Jiaozhou Bay Marine Ecosystem Research Station Chinese Academy of SciencesQingdao 266071China University of Chinese Academy of Sciences Beijing 100049China

Ulva prolifera is the causative species of the annually occurring large-scale green tides in China since *** specific biological features on reproductivity strategies,as well as intra-species genetic diversity,are still largely unknown,especially at the genome level,despite their importance in understanding the formation and outbreak of massive green *** the present study,the restriction site-associated DNA genotyping approach(2b-RAD)was adopted to identify the genome-wide single-nucleotide polymorphisms(SNPs)of 54 individual thalli including samples collected from Subei Shoal in 2019 and Qingdao coast from 2019 to *** genotype results revealed that most of the thalli in 2019 and 2020 were haploid gametophytes,while only half of the thalli were gametophytes in 2021,indicating flexibility in the reproductive strategies for the formation of the green tides among different years and the dominance of asexual and vegetative reproductive mode for the floating ***,population analysis was conducted,and it revealed a very low genetic diversity among samples from Subei Shoal and the Qingdao coast in the same year and a higher divergence among samples in different *** results showed the efficiency of 2b-RAD in the exploration of SNPs in *** and provided the first genome-wide scale evidence for the origin of the large-scale green tides on the Qingdao *** study improved our understanding of the reproductive strategy and genetic diversity of the green tide causative species and will help further reveal the biological causes of the green tide in China.

关键词： green tide Ulva prolifera 2b-RAD single-nucleotide polymorphism(SNP) reproductive strategy genetic diversity