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Coherence Time Measurement of Picosecond Pulses Using Reverse Saturable Absorption in Lead Phthalocyanine

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Chinese Journal of Lasers 1997年第4期 45-49页

作者： LI Feng song yinglin YANG Kunlui shutian LI Chunfei(Department of Applied Physics, Harbin Institute of Technology, Harbin 150001, China)DUAN Wubiao WU Yiqun(Department of Chemistry, Heilongjiang University, Harbin 150001, China)

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关键词： lead phthalocyanine reverse saturable absorption coherence time

实物还是体验?产品脱销对于消费者实物型产品偏好的影响

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南开管理评论 2024年第6期27卷 184-196页

作者：段珅孟陆宋晓菲寇思宁中南财经政法大学工商管理学院西南交通大学经济管理学院再惠(上海)网络科技有限公司北京第二外国语学院商学院

脱销消费情境对企业和消费者都存在着不容忽视的影响作用。本研究发现,脱销会增加消费者对实物型消费的偏好。实验1a和实验1b验证了在不同情境下消费者遭遇产品脱销时,会在随后的体验型和实物型产品选择中更偏好实物型产品。实验2a和实... 详细信息

脱销消费情境对企业和消费者都存在着不容忽视的影响作用。本研究发现,脱销会增加消费者对实物型消费的偏好。实验1a和实验1b验证了在不同情境下消费者遭遇产品脱销时,会在随后的体验型和实物型产品选择中更偏好实物型产品。实验2a和实验2b分别通过测量和操纵方式,验证了当消费者遭遇产品脱销时,会感知到控制感受威胁并通过选择实物型产品补偿控制感的缺失。实验3则验证了内外控人格的边界作用。本研究结论对于企业捕捉消费者偏好变化、应对脱销难题、制定营销策略等具有重要的实践和理论价值。

关键词：脱销体验型产品实物型产品控制感内外控人格

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A Quick Numerical Method for Analyzing Nonlinear Effects of Excited State Absorption

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Chinese Journal of Lasers 1999年第6期8卷 3-5页

作者： ZHANG Xueru DENG Xiaoxu song yinglin LIU shutian LI Chunfei (Department of Applied Physics, Harbin Institute of Technology, Harbin 150001, China) 哈尔滨工业大学应用物理系黑龙江哈尔滨

A semi analytical difference method for analyzing nonlinear effects of excited state optical absorption is presented. In comparison with Hughes’ method and traditional difference method, the advantages of the semi an... 详细信息

关键词： excited state nonlinear absorption numerical analysis

Ultra-small superparamagnetic iron oxide nanoparticles for intra-articular targeting of cartilage in early osteoarthritis

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Regenerative Biomaterials 2023年第1期10卷 1111-1121页

作者： Jun Wu Changqiang Wu Zhongyuan Cai Haojie Gu Li Liu Chunchao Xia Su lui Qiyong Gong Bin song Hua Ai Institute for Disaster Management and Reconstruction Sichuan UniversityChengdu 610207China Medical Imaging Key Laboratory of Sichuan Province School of Medical ImagingNorth Sichuan Medical CollegeNanchong 637000China National Engineering Research Center for Biomaterials Sichuan UniversityChengdu 610064China Department of Radiology West China HospitalSichuan UniversityChengdu 610041China Department of Radiology Huaxi MR Research Center(HMRRC)Frontiers Science Center for Disease-Related Molecular NetworkState Key Laboratory of BiotherapyWest China HospitalSichuan UniversityChengdu 610041China Functional and Molecular Imaging Key Laboratory of Sichuan Province Key Laboratory of Transplant Engineering and ImmunologyNHCResearch Unit of PsychoradiologyChinese Academy of Medical SciencesChengdu 610064China Department of Radiology West China Xiamen Hospital of Sichuan UniversityFujianXiamen 361000China Department of Radiology Sanya People’s HospitalHainanSanya 572000China

Early diagnosis of osteoarthritis(OA)is critical for effective cartilage ***,lack of blood vessels in articular cartilage poses a barrier to contrast agent delivery and subsequent diagnostic *** address this challenge,we proposed to develop ultra-small superparamagnetic iron oxide nanoparticles(SPIONs,4 nm)that can penetrate into the matrix of articular cartilage,and further modified with the peptide ligand WYRGRL(particle size,5.9 nm),which allows SPIONs to bind to type II collagen in the cartilage matrix and increase the retention of *** II collagen in the cartilage matrix is gradually lost with the progression of OA,consequently,the binding of peptide-modified ultra-small SPIONs to type II collagen in the OA cartilage matrix is less,thus presenting different magnetic resonance(MR)signals in OA group from the normal *** introducing the AND logical operation,damaged cartilage can be differentiated from the surrounding normal tissue on T1 and T2 AND logical map of MR images,and this was also verified in histology ***,this work provides an effective strategy for delivering nanosized imaging agents to articular cartilage,which could potentially be used to diagnosis joint-related diseases such as osteoarthritis.

关键词： early osteoarthritis magnetic resonance imaging superparamagnetic iron oxide collagen type II targeting peptide

DETERMINATION　OF　HISTIDINE　BY　DIFFERENTIAL　PULSE　ADSORPTIVE　STRIPPING　VOLTAMMETRY　OF　ITS　NICKEL(Ⅱ)COMPLEX

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Chinese Chemical Letters 1995年第9期6卷 783-786页

作者： Xiao Li ZHANG Cheng song CIA lui Ai DENG(Department of Chemistry, Shandong University, Jinan. 250100) Shandong Univ Dept Chem Jinan 250100 Peoples R China

Abstract: Histidine was determined at the 5. 0 ×10-1.0×10-5mol/L level by differential pulse adsorptive cathodic etripping voltammetry at a hanging mercury drop electrode using the reduction peak of its nickel(Ⅱ) complex at -1. 16v(vs. Ag(AgCl) obtained in pH-10. 2 borate buffer solution. Other amino acid. do not interfere . This methed has been used for the direct determination of histidiue in serum.

关键词： ITS NICKEL VOLTAMMETRY COMPLEX BY ADSORPTIVE

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Advances in magnetic resonance imaging contrast agents for glioblastoma-targeting theranostics

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Regenerative Biomaterials 2021年第6期8卷 273-296页

作者： Zijun Wu Lixiong Dai Ke Tang Yiqi Ma Bin song Yanrong Zhang Jinxing Li Su lui Qiyong Gong Min Wu Huaxi MR Research Center(HMRRC) Department of RadiologyFunctional and Molecular Imaging Key Laboratory of Sichuan ProvinceWest China HospitalSichuan UniversityChengdu 610041China Wenzhou Institute University of Chinese Academy of SciencesWenzhouZhejiang 325000China Department of Radiology School of MedicineStanford UniversityStanfordCA 94305USA

Glioblastoma(GBM)is the most aggressive malignant brain tumour,with a median survival of 3 months without treatment and 15 months with *** GBM diagnosis can significantly improve patient survival due to early treatment and management *** resonance imaging(MRI)using contrast agents is the preferred method for the preoperative detection of GBM ***,commercially available clinical contrast agents do not accurately distinguish between GBM,surrounding normal tissue and other cancer types due to their limited ability to cross the blood-brain barrier,their low relaxivity and their potential *** GBM-specific contrast agents are urgently needed to overcome the limitations of current contrast *** advances in nanotechnology have produced alternative GBM-targeting contrast *** surfaces of nanoparticles(NPs)can be modified with multimodal contrast imaging agents and ligands that can specifically enhance the accumulation of NPs at GBM *** advanced imaging technology,multimodal NP-based contrast agents have been used to obtain accurate GBM diagnoses in addition to an increased amount of clinical diagnostic *** can also serve as drug delivery systems for GBM *** review focuses on the research progress for GBMtargeting MRI contrast agents as well as MRI-guided GBM therapy.

关键词： glioblastoma MRI targeted contrast agents therapy drug delivery

Kinetically inert manganese(II)-based hybrid micellar complexes for magnetic resonance imaging of lymph node metastasis

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Regenerative Biomaterials 2023年第1期10卷 1122-1134页

作者： Kai Chen Zhongyuan Cai Yingzi Cao Lingling Jiang Yuting Jiang Haojie Gu Shengxiang Fu Chunchao Xia Su lui QiyongGong Bin song Hua Ai National Engineering Research Center for Biomaterials Sichuan UniversityChengdu 610064China Department of Radiology West China HospitalSichuan UniversityChengdu 610041China Huaxi MR Research Center(HMRRC) Department of RadiologyFrontiers Science Center for Disease-Related Molecular NetworkState Key Laboratory of BiotherapyWest China HospitalSichuan UniversityChengdu 610041China Functional and Molecular Imaging Key Laboratory of Sichuan Province Key Laboratory of Transplant Engineering and ImmunologyNHCResearch Unit of PsychoradiologyChinese Academy of Medical SciencesChengdu 610041China Department of Radiology West China Xiamen Hospital of Sichuan UniversityFujianXiamen 361000China Department of Radiology Sanya People’s HospitalSanya 572000China

The localization and differential diagnosis of the sentinel lymph nodes(SLNs)are particularly important for tumor staging,surgical planning and *** this work,kinetically inert manganese(II)-based hybrid micellar complexes(MnCs)for magnetic resonance imaging(MRI)were developed using an amphiphilic manganese-based chelate(C18-PhDTA-Mn)with reliable kinetic stability and self-assembled with a series of amphiphilic PEG-C18 polymers of different molecular weights(C18En,n=10,20,50).Among them,the probes composed by 1:10 mass ratio of manganese chelate/C18En had slightly different hydrodynamic particle sizes with similar surface charges as well as considerable relaxivities(∼13 mM^(−1)s^(−1)at 1.5 T).In vivo lymph node imaging in mice revealed that the MnC MnC-20 formed by C18E20 with C18-PhDTA-Mn at a hydrodynamic particle size of 5.5 nm had significant signal intensity brightening effect and shortened T1 relaxation *** an imaging probe dosage of 125μg Mn/kg,lymph nodes still had significant signal enhancement in 2 h,while there is no obvious signal intensity alteration in non-lymphoid *** 4T1 tumor metastatic mice model,SLNs showed less signal enhancement and smaller T1 relaxation time variation at 30 min post-injection,when compared with normal lymph *** was favorable to differentiate normal lymph nodes from SLN under a 3.0-T clinical MRI *** conclusion,the strategy of developing manganese-based MR nanoprobes was useful in lymph node imaging.

关键词： kinetically inert amphiphilic manganese chelate T1 contrast agent sentinel lymph node magnetic resonance imaging

Donald ***,the master mentor:Testimonials from former international students

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Earthquake Science 2022年第1期35卷 67-70页

作者： Xiaodong song Sidao Ni Ying Tan Alex song Risheng Chu Daoyuan Sun Shengji Wei Semechah lui Voon Hui Lai Institute of Theoretical and Applied Geophysics School of Earth and Space SciencesPeking UniversityBeijing 100871China State Key Laboratory of Geodesy and Earth's Dynamics Innovation Academy of Precision Measurement Science and TechnologyChinese Academy of SciencesWuhan 430077China Chevron Technical Center Houston TX77002USA Department of Earth Sciences University College LondonLondon WC1E 6BTUnited Kingdom Laboratory of Seismology and Physics of Earth's Interior School of Earth and Space SciencesUniversity of Science and Technology of ChinaHefei 230026China Asian School of the Environment/Earth Observatory of Singapore Nanyang Technological UniversitySingapore 639798Singapore Department of Earth Sciences University of TorontoTorontoONM5S 3B1Canada Research School of Earth Sciences The Australian National UniversityACT 2601Australia

Don trained many *** over the〜5 decades of his career,at least 45 were advised or co-advised according to a Caltech account.A large number were international students including a high percentage of Chinese *** contributors to this article graduated over a time span of 26 years,and we are now distributed in 6 countries across 14 time zones,yet we represent only a small fraction of his former students and postdocs.

关键词： Donald career trained

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Retro-enantio isomer of angiopep-2 assists nanoprobes across the blood-brain barrier for targeted magnetic resonance/fluorescence imaging of glioblastoma

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Signal Transduction and Targeted Therapy 2021年第9期6卷 2870-2882页

作者： Ruoxi Xie Zijun Wu Fanxin Zeng Huawei Cai Dan Wang Lei Gu Hongyan Zhu Su lui Gang Guo Bin song Jinxing Li Min Wu Qiyong Gong Huaxi MR Research Center(HMRRC) Department of RadiologyFunctional and Molecular Imaging Key Laboratory of Sichuan ProvinceWest China HospitalSichuan UniversityChengduChina Research Unit of Psychoradiology Chinese Academy of Medical SciencesChengduChina Department of Clinic Medical Center Dazhou Central HospitalDazhouChina Laboratory of Clinical Nuclear Medicine Department of Nuclear MedicineWest China HospitalSichuan UniversityChengduChina State Key Laboratory of Biotherapy and Cancer Center West China HospitalSichuan Universityand Collaborative Innovation Center for BiotherapyChengduChina Department of Chemical Engineering Stanford UniversityStanfordCaliforniaUSA

Glioblastoma(GBM),one of the most common primary intracranial malignant tumours,is very difficult to be completely excised by surgery due to its irregular ***,we use an MRI/NIR fluorescence dual-modal imaging nanoprobe that includes superparamagnetic iron oxide nanoparticles(SPIONs)modified with indocyanine(Cy7)molecules and peptides(ANG orDANG)to locate malignant gliomas and guide accurate *** peptides/Cy7-SPIONs probes displayed excellent tumour-homing properties and barrier penetrating abilities in vitro.

关键词： tumour malignant surgery