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Biomedical and Environmental Sciences 2010年第4期23卷 305-311页

作者： sohail ejaz AHMED ejaz AMARA sohail CHAE WOONG LIM Department of Clinical Neurosciences Neurology Unit Addenbrookes Hospital University of Cambridge District Headquarter Hospital Government Social Security Hospital Gujranwala Pakistan Biosafety Research Institute and College of Veterinary Medicine Chonbuk National University

Objective Embryonic movements （EM） and angiogenesis pathways are evolutionarily conserved mechanisms which are essential for proper embryonic development. Deviations in these processes by exposure to cigarette smoke condensate （CSC） may cause vascular and morphogenetic disorders. Methods Using chicken and mouse embryos, we have demonstrated the in vivo effects of CSC on EM, vascular development, and organogenesis. Results Examination of the CSC exposed chicken embryos revealed a significant reduction in EM, stunted growth, deviated pattern of blood vessels, hemorrhages, and localized necrosis. Likewise, mouse embryos that were exposed to CSC at E8.5 and E9.5 died between E11.5 and E12.5, respectively. These mouse embryos showed defects in morphogenesis and remodeling of the embryonic vasculature, while littermate controls showed normal development. Conclusion Cigarette smoking during pregnancy is fatal for growing embryos. CSC may induce the remodeling of embryonic vasculature, leading to various pathologies.

关键词： Angiogenesis Embryonic movements Cigarette smoke condensate Vascular remodeling

Total Particulate Matter and Wound Healing: An in vivo Study with Histological Insights

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Biomedical and Environmental Sciences 2009年第4期22卷 278-287页

作者： sohail ejaz MUHAMMAD ASHRAF MUHAMMAD NAWAZ CHAE WOONG LIM Department of Clinical Neurosciences Neurology Unit Addenbrookes Hospital University of Cambridge Angiogenesis and Toxicology Research Laboratory Department of Toxicology and Pharmacology University of Veterinary and Animal Sciences Biosafety Research Institute and College of Veterinary Medicine Chonbuk National University

Objectives Wound healing in the skin is a multifarious orchestration of cellular processes and cigarette smoking may be a cause for delayed wound healing. The aim of this study was to investigate the plausible association between exposures of cigarette total particulate matter （TPM） and wound healing. Methods An in vivo wound healing model of mice was established for determination of assorted events of wound healing, dermal matrix regeneration, re-epithelialization, and neovascularization. A total of 72 adult mice, separated in eight groups, were exposed to TPM for 12 days. Results A highly considerable diminution in wound closure （P〈0.001） was pragmatic among all TPM-treated mice from day 6 to day 8 post-wounding. Histological investigations unveiled a noteworthy impede in the outcome of re-epithelialization, dermal matrix regeneration and maturation of collagen bundles among all TPM-exposed wounds. Delayed commencement of neovascularization was pragmatic among all TPM-treated mice, on day 12 post wounding. Abbot curve, angular spectrum, and other different parameters of 3D surface behavior of wounds revealed a very highly significant reduction （P〈0.001） in angiogenesis on days 6 and 8 post-wounding, which points that application of TPM instigates extensive delay in trigging the progression of angiogenesis, resulting in delayed onset of wound healing. Conclusion Our annotations validate the damaging effects of TPM on wound healing and excessive use of TPM may lead to the production of chronic wounds and oral ulcers.

关键词： Cigarette Total particulate matter Wound healing Re-epithelialization Angiogenesis

Mutagenic and cytotoxic potential of Endosulfan and Lambda-cyhalothrin—In vitro study describing individual and combined effects of pesticides

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Journal of Environmental Sciences 2014年第7期26卷 1471-1479页

作者： Umber Saleem sohail ejaz Muhammad Ashraf Muhammad Ovais Omer Imran Iltaf Zainab Batool Riffat Fatima Msbah Afzal Department of Pharmacology & Toxicology University of Veterinary and Animal Sciences Lahore 54000 Pakistan Department of Clinical Neurosciences Neurology Unit Addenbrooke's Hospital University of Cambridge Cambridge UK Microbiology Section Quality Operations Laboratory University of Veterinary and Animal Sciences Lahore Pakistan

Excessive use of pesticides poses increased risks to non target species including humans. In the developing countries, lack of proper awareness about the toxic potential of pesticides makes the farmer more vulnerable to pesticide linked toxicities, which could lead to diverse pathological conditions. The toxic potential of a pesticide could be determined by their ability to induce genetic mutations and cytotoxicity. Hence, determination of genetic mutation and cytotoxicity of each pesticide is unavoidable to legislate health and safety appraisal about pesticides. The objective of current investigation was to determine the genotoxic and cytotoxic potential of Endosulfan（EN） and Lambda-cyhalothrin（LC）; individually and in combination. 3-（4,5-Dimethylthiazol-2-yl）-2,5-Diphenyltetrazolium Bromide（MTT） assay was utilized to determine cytotoxicity, while two mutant histidine dependent Salmonella strains（TA98, TA100） were used to determine the mutagenicity of EN and ***, mutagenicity assay was conducted with and without S9 to evaluate the effects of metabolic activation on mutagenicity. Even though a dose dependent increase in the number of revertant colonies was detected with EN against both bacterial strains, a highly significant（p 〈 0.05） increase in the mutagenicity was detected in TA98 with S9. In comparison, data obtained from LC revealed less mutagenic potential than EN. Surprisingly,the non-mutagenic individual-concentrations of EN and LC showed dose dependent mutagenicity when combined. Combination of EN and LC synergistically induced mutagenicity both in TA98 and TA100. MTT assay spotlighted comparable dose dependent cytotoxicity effects of both pesticides. Interestingly, the combination of EN and LC produced increased reversion and cytotoxicity at lower doses as compared to each pesticide, concluding that pesticide exposure even at sub-lethal doses can produce cytotoxicity and genetic mutations, which could lead to carcinogenicity.

关键词： Endosulfan Lambda-cyhalothrin Mutagenicity Cytotoxicity

Analysis of cerium substitution in Co-Sr based spinel ferrites for high frequency application

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Journal of Rare Earths 2024年第9期42卷 1755-1763,I0005页

作者： Laura Khudaysh Inas A.Ahmed Syeda Rabia ejaz Sajjad Ahmad Khan Yasir A.Haleem Mohamed M.Ibrahim Mahmood Ali Hafiz Muhammad Tahir Farid Zeinhom M.El-Bahy Department of Physics Faculty of ScienceJazan UniversityJazan45142Saudi Arabia Department of Chemistry Faculty of ScienceKing Khalid UniversityAbha62224Saudi Arabia Department of Physics The Government Sadiq College Women UniversityBahawalpur63100Pakistan Institute of Physics Khwaja Fareed University of Engineering and Information TechnologyRahim Yar Khan64200Pakistan Department of Chemistry College of ScienceTaif UniversityP.O.Box 11099Taif21944Saudi Arabia Centre of Excellence in Solid State Physics University of the PunjabLahorePakistan Department of Physics Government CollegeTaunsa Sharif32200Pakistan Department of Chemistry Faculty of ScienceAl-Azhar UniversityNasr City11884CairoEgypt

Spinel ferrites exhibit exceptional magnetic properties,making them a distinctive class of magnetic *** sol-gel technique was utilized for the synthesis of spinel ferrites with the chemical formula Co_(0.6)Sr_(0.4)Ce_(x)Fe_(2-x)O_(4). Following that,a comprehensive X-ray diffraction analysis unveiled the crystalline cubic structure of the synthesized *** the utilization of the M-H loop approach,the ferromagnetic attributes of ferrites were assessed,and the assimilation of rare earth elements led to substantial enhancements in saturation magnetization,remanence,and *** ferrites with a high concentration of rare earth elements have improved direct current resistivity and activation *** logarithm of a material's resistance increased from 5.29 to 8.12 Ω·cm as cerium is *** a change in the amount of cerium,the activation energy goes up from 0.19 to *** changing the frequency from 5.5 to 9.5 GHz,the dielectric characteristics were *** the frequency goes up,the dielectric constant goes *** ferrites that have been made better in every way can be used in high-frequency applications.

关键词： Activation energy DC electrical resistance Remanence magnetization Cobalt strontium spinel ferrites High frequency application Rare earths

Fuzzy Optimal Control Design for Ship Steering

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Transactions of Nanjing University of Aeronautics and Astronautics 2019年第3期36卷 459-467页

作者： ejaz Muhammad CHEN Mou College of Automation Engineering Nanjing University of Aeronautics and Astronautics

This paper presents a method to design a control scheme for nonlinear systems using fuzzy optimal *** the design process,the nonlinear system is first converted into local subsystems using sector non linearity approach of Takagi Sugeno(T S)fuzzy *** each local subsystem,an optimal control is ***,the parameters of local controllers are defuzzified to construct a global optimal *** prove the effectiveness of this control scheme,simulations are performed using the mathematical model of Esso Osaka tanker ship for set point regulation with and without disturbance and reference *** addition,the simulation results are compared with that of a PID controller for further verification and *** has been shown that the proposed optimal controller can be used for the nonlinear ship steering with good rise time,zero steady state error and fast settling time.

关键词： Takagi Sugeno(T S) fuzzy modeling optimal control optimal linear quadratic tracker (LQT) ship steering

China-Pakistan Economic Corridor： Will It Sustain Itself？

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Fudan Journal of the Humanities and Social Sciences 2017年第2期10卷 145-159页

作者： ejaz Hussain Department of Social Sciences Iqra University Islamabad Pakistan

This paper attempts to measure and explain the sustainability of China- Pakistan Economic Corridor （CPEC） by employing rational choice theory. Methodologically, the qualitative study relies on primary data in terms of elite interviews and secondary sources such as journals articles. This theory-guided empirical research has identified two sets of challenges, internal and external, that the economic corridor faces. Broadly, the challenges range from economic slow- down, political instability, religious extremism and terrorism that have taken toll of Pakistani economy, society and the state. The paper has provided policy input in terms of urging Pakistani government to reform its educational system and correct political instability along with targeting all types of militant organizations. More- over, the study urges China to engage regional stakeholders in CPEC to realize regional and trans-regional connectivity to achieve economic integration of the market.

关键词： CPEC Trade Balochistan Xinjiang - Belt and Road Initiative -China-Pakistan Economic Corridor

Aluminium and cerium co-doped ZnO nanoparticles:Facile and inexpensive synthesis and visible light photocatalytic performances

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Journal of Rare Earths 2021年第2期39卷 151-159页

作者： Irshad Ahmad Muhammad Shoaib Akhtar ejaz Ahmed Mukhtar Ahmad Department of Physics Bahauddin Zakariya UniversityMultan60800Pakistan School of Computer and Communication Lanzhou University of TechnologyLanzhou 730000China

Facile combustion route synthesized Al and Ce co-doped ZnO nanoparticles photocatalysts were characterized using XRD,SEM,BET,EDS,UV-visible DRS,PL,photocurrent and EIS *** and SEM analyses identify that crystallite and particle size is reduced from 13.26 to 11.88 nm with introduction of Al and Ce into ZnO which assists inhibiting the recombination of photo generated charge *** DRS spectra indicate that optical assimilation of ZnO is significantly increased to visible region(-406 nm)and band gap reduces from 3.18 to 3.06 eV with introduction of Al and Ce *** impedance spectroscopy analysis under visible light illumination confirms the enhancement in visible light activity of Al and Ce co-doped ZnO nanoparticles as *** enhanced activity of Al and Ce co-doped ZnO photocatalyst can be ascribed to enhanced light assimilation,high surface area and efficient charge transfer *** results reveal that by incorporating precise amount of Al(~2%)and Ce(~2%)into ZnO,a highly efficient catalyst can be synthesized that have degraded almost 95%methyl orange(MO)dye in just 45 ***,the influence of various operational parameters such as solution pH,catalyst dose,dye concentration,airflow rate and light intensity on photodecomposition of MO was *** rmore,a possible mechanism for Al and Ce modified ZnO was proposed and designed photocatalysts demonstrates good stability in aqueous medium.

关键词： Nanoparticles ZnO Combustion MO decomposition PL Rare earths

Computational Modeling of Reaction-Diffusion COVID-19 Model Having Isolated Compartment

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Computer Modeling in Engineering & Sciences 2023年第5期135卷 1719-1743页

作者： Muhammad Shoaib Arif Kamaleldin Abodayeh Asad ejaz Department of Mathematics and Sciences College of Humanities and SciencesPrince Sultan UniversityRiyadh11586Saudi Arabia Department of Mathematics Air UniversityPAF Complex E-9Islamabad44000Pakistan

Cases of COVID-19 and its variant omicron are raised all across the *** most lethal form and effect of COVID-19 are the omicron version,which has been reported in tens of thousands of cases daily in numerous *** WHO(World health organization)records on 30 December 2021,the cases of COVID-19 were found to be maximum for which boarding individuals were found 1,524,266,active,recovered,and discharge were found to be 82,402 and 34,258,778,*** there were 160,989 active cases,33,614,434 cured cases,456,386 total deaths,and 605,885,769 total samples *** far,1,438,322,742 individuals have been *** coronavirus or COVID-19 is inciting panic for several *** is a new virus that has affected the whole *** have introduced certain ways to prevent the *** can lower the danger of infection by reducing the contact rate with other *** crowded places and social events withmany people reduces the chance of one being exposed to the *** deadly COVID-19 spreads *** is thought that the upcoming waves of this pandemicwill be evenmore *** have presented severalmathematical models to study the pandemic and predict future *** need of the hour is to restrict the mobility to control the infection from ***,separating affected individuals from healthy people is essential to control the *** consider the COVID-19 model in which the population is divided into five *** present model presents the population’s diffusion effects on all susceptible,exposed,infected,isolated,and recovered *** reproductive number,which has a key role in the infectious models,is *** equilibrium points and their stability is *** numerical simulations,finite difference(FD)schemes like nonstandard finite difference(NSFD),forward in time central in space(FTCS),and Crank Nicolson(CN)schemes are *** core characteristics

关键词： Reproductive number stability Routh Hurwitz criterion variational matrix NSFD scheme FTCS scheme Crank Nicolson scheme consistency

Joint Design of QC-LDPC Codes for Coded Relay Cooperation

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Chinese Journal of Electronics 2016年第1期25卷 179-184页

作者： TANG Lei YANG Fengfan ZHANG Shunwai SAQIB ejaz LUO Lin College of Electronic and Information Engineering Nanjing University of Aeronautics and Astronautics School of Communication Engineering Nanjing Institute of Technology College of Information Science and Engineering Southeast University

This paper proposes an effective method to jointly design girth-4 cycle-free Quasi-cyclic(QC) Lowdensity parity-check(LDPC) codes for multi-relay cooperation in a Rayleigh fading channel, where the joint iterative decoding by Min-sum algorithm(MSA) based on the introduced joint Tanner graph is also presented at the destination. Theoretical analysis and simulation show that the proposed QC-LDPC coded cooperation outperforms the randomly coded cooperation under the same conditions.

关键词： Coded cooperation Low-density parity check(LDPC) codes Min-sum algorithm(MSA) Joint it erative decoding Treble-layer Tanner graph

Temperature-controlled fabrication of hydrophilic manganese oxide microspheres as high-performance electrode materials for supercapacitors

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Chinese Chemical Letters 2023年第5期34卷 516-520页

作者： Yuchen Wang Yaoyu Liu Ahsan ejaz Kai Yan Guangdong Provincial Key Laboratory of Environmental Pollution Control and Remediation Technology School of Environmental Science and EngineeringSun Yat-sen UniversityGuangzhou 510275China Department of Civil Engineering Mirpur University of Science and TechnologyAJKMirpur 10250Pakistan

The supercapacitive properties of manganese oxides(MnO_(x))are strongly affected by their crystal ***,the relationship between the crystal structure and supercapacitive performance of Mn O_(x)is ***,a temperature-controlled fabrication method was developed to achieve MnO_(2),Mn_(3)O_(4),MnO and Mn_(2)O_(3)microspheres with various crystal structure as electrode materials tunable for *** detailed material and electrochemical characterizations revealed the structureactivity relationship of Mn O_(x)microspheres by systematically investigating the effect of valence state,specific surface area,conductivity and morphology on supercapacitive *** these MnO_(x)materials,nanoneedle-like Mn O_(2)delivered a relatively high specific capacitance of 274.1 F/g at 1 A/g due to a high Mn valence state of+4,a large specific surface area of 113.4 m^(2)/g and a desirable electronic conductivity of 1.73×10^(-5)S/***,MnO_(2)presented a remarkable cycle stability with 115%capacitance retention after 10,000 cycles owing to the enhancement of *** work not only provides a facile strategy to modulate MnO_(x)crystal structure,but also offers a deep understanding of structure-dependent supercapacitive performance of MnO_(x).

关键词： Temperature-controlled Manganese oxide Microsphere Supercapacitors Hydrophilic