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Highly Sensitive Rayleigh Wave Hydrogen Sensors with WO_(3) Sensing Layers at Room Temperature

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Chinese Physics Letters 2011年第11期28卷 56-59页

作者： WANG Cheng FAN Li ZHANG Shu-Yi YANG Yue-Tao ZHOU Ding-Mao shui xiu-ji Lab of Modern Acoustics Institute of AcousticsNanjing UniversityNanjing 210093

Rayleigh wave hydrogen sensors based on 128∘YX-LiNbO_(3) substrates with WO_(3) sensing layers operating at room temperature are *** experimental results indicate that the WO_(3) layers obtained by a sol-gel method have much higher sensitivities because the sensing layers produced by the sol-gel method have small grains and high roughness and *** is also confirmed that in the sol-gel method,keeping WO_(3) solutions at low temperature and/or decreasing the viscosity of the solutions can decrease the grain sizes and increase the hydrogen-absorbability of the sensing *** the optimized preparation conditions,the high sensitivity of the hydrogen sensors at room temperature is obtained,in which 1%hydrogen in natural air induces the frequency shift of 72 kHz at the operating frequency of 124.2 MHz.

关键词： Rayleigh roughness method

Regulation and function of endoplasmic reticulum autophagy in neurodegenerative diseases

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Neural Regeneration Research 2025年第1期20卷 6-20页

作者： xiu-Yun Zhao De-En Xu Ming-Lei Wu ji-Chuan Liu Zi-Ling Shi Quan-Hong Ma Department of Neurology and Clinical Research Center of Neurological Disease the Second Affiliated Hospital of Soochow UniversitySuzhouJiangsu ProvinceChina Institute of Neuroscience&jiangsu Key Laboratory of Translational Research and Therapy for Neuro-Psycho-Diseases Soochow UniversitySuzhouJiangsu ProvinceChina Department of Neurology Jiangnan University Medical CenterWuxiJiangsu ProvinceChina

The endoplasmic reticulum,a key cellular organelle,regulates a wide variety of cellular *** reticulum autophagy,one of the quality control systems of the endoplasmic reticulum,plays a pivotal role in maintaining endoplasmic reticulum homeostasis by controlling endoplasmic reticulum turnover,remodeling,and *** this review,we briefly describe the endoplasmic reticulum quality control system,and subsequently focus on the role of endoplasmic reticulum autophagy,emphasizing the spatial and temporal mechanisms underlying the regulation of endoplasmic reticulum autophagy according to cellular *** also summarize the evidence relating to how defective or abnormal endoplasmic reticulum autophagy contributes to the pathogenesis of neurodegenerative *** summary,this review highlights the mechanisms associated with the regulation of endoplasmic reticulum autophagy and how they influence the pathophysiology of degenerative nerve *** review would help researchers to understand the roles and regulatory mechanisms of endoplasmic reticulum-phagy in neurodegenerative disorders.

关键词： autophagy endoplasmic reticulum endoplasmic reticulum autophagy endoplasmic reticulum quality control system endoplasmic reticulum receptors endoplasmic reticulum-associated degradation neurodegeneration neurodegenerative disease selective autophagy unfolded protein response

利用扫描电子声显微镜技术实现定量分层成像(英文)

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南京大学学报（自然科学版） 2010年第6期46卷 688-696页

作者：朱守经张淑仪高椿明张仲宁水修基张秀玲佘万东南京大学声学研究所近代声学重点实验室南京210093 南京鼓楼医院南京大学医学院南京210008

电子声热波显微镜技术成像过程中,由于不同深度的热源具有不同的相位与幅值,因此产生的声信号的相位与幅值对应于不同的深度和结构.由于热波是高衰减波,所以特别适合于表面层附近结构的检测与分析.实验上利用压电换能器检测声信号,其输... 详细信息

电子声热波显微镜技术成像过程中,由于不同深度的热源具有不同的相位与幅值,因此产生的声信号的相位与幅值对应于不同的深度和结构.由于热波是高衰减波,所以特别适合于表面层附近结构的检测与分析.实验上利用压电换能器检测声信号,其输出的电信号通过锁相放大器加以放大、并抑制其余不同频率和相位的信号和噪声,因此可以增强特定频率和相位的声信号输出.根据检测到的不同相位的声信号,即可分析样品不同深度的结构,因而扫描电子声热波显微镜技术可以实现分层成像.为了定量估计不同深度的结构对检测到的声信号的贡献,利用热传导方程和热弹方程及其边界条件,可以解得热波在不同深度产生的温度场及声场,因而可求得不同深度的热源产生的声信号的振幅和相位.根据压电方程,可求得不同深度的声源对压电换能器输出电信号的贡献.将理论的计算与实验结果进行拟合,可以定量确定样品的深度剖面结构.本文利用上述成像技术,对大白鼠的肝脏和心脏组织进行分层成像,得到不同深度的分层图像.同时,利用电子声热波检测技术,可测得大白鼠的组织的显微镜样品的热扩散率,其结果为0.45到0.65 mm2/s之间.通过与以前文章报道的猪肝脏组织的显微镜样品测量得到的热扩散率值比较,它们之间的偏离约为7%,由此可知大白鼠的热扩散率测量值是合理的.最后,通过电子声热波成像理论和检测实验结果的比照,对实验的分层成像结果进行数值拟合,可对大白鼠组织进行定量深度分层分析,分层成像深度在一个热波波长范围内,实验中检测深度约为数十微米量级.由此说明,扫描电子声热波显微镜技术可以非破坏性地对不均匀的生物组织和固体材料的表面和亚表面的结构进行三维定量分层成像和表征.

关键词：热波技术分层成像扫描电子声显微镜技术

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脉冲光声量热法研究氧合血红蛋白的光解反应

南京大学学报（自然科学版） 2007年第1期43卷 73-78页

作者：杨宁利张淑仪孙利渠敏水修基陈慧兰李家璜华子春南京大学声学研究所近代声学实验室南京210093 南京大学化学系配位化学实验室南京210093 南京大学医药生物技术实验室南京210093

时间分辨脉冲光声量热法是利用脉冲激光激发化学物质的光解反应，反应中产生的热能将激发声波，声波的振幅和相位即反映光解反应的中间过程．因此时间分辨光声量热技术是研究光致解离动力学信息的十分有效的方法．利用时间分辨光声量热... 详细信息

时间分辨脉冲光声量热法是利用脉冲激光激发化学物质的光解反应，反应中产生的热能将激发声波，声波的振幅和相位即反映光解反应的中间过程．因此时间分辨光声量热技术是研究光致解离动力学信息的十分有效的方法．利用时间分辨光声量热法测量了激光诱导人、牛，猪、马和兔的氧合血红蛋白光解反应的焓变和结构体积变化．实验中采用波长532nm、脉冲宽度8ns的脉冲激光作为激发光源，光声信号由共振频率为1．5MHz的PZT压电换能器接收，所以实验系统的响应时间范围在10^2ns量级。已知在氧合血红蛋白的光解反应中可以检测到4个过程具有4种不同的反应时间，其中三级结构重组在137-470ns左右．考虑实验系统的时间窗口，所测结果应与血红蛋白的三级结构变化相对应．测量结果显示：不同种类的哺乳动物氧合血红蛋白光解反应中，对应三级结构变化的焓变和结构体积变化各不相同．最后对这一结论进行了讨论．

关键词：氧合血红蛋白光声量热光解反应焓变结构体积变化

Investigation of the dynamic characteristics of a dual rotor system and its start-up simulation based on finite element method

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2013年第4期14卷 268-280页

作者： Zhong-xiu FEI shui-guang TONG Chao WEI Institute of Chemical Machinery Engineering Zhejiang University Mechanical Design Institute Zhejiang University Institute of Thermal Engineering and Power Systems Zhejiang University

Recently,the finite element method(FEM) has been commonly applied in the engineering analysis of rotor *** moments,rotary inertia,transverse shear deformation and gravity can be included in computational models of rotor-bearing *** this paper,a finite element model and its solution method are presented for the calculation of the dynamics of dual rotor systems.A typical structure with two rotor shafts is discussed and the procedure for obtaining the coupling motion equations of the subsystems is illustrated.A computer program is developed to solve critical speeds and to simulate the transient *** influence of gyroscopic moments on co-rotation and counter-rotation is analyzed,and the effect of the speed ratio on critical speed is *** dynamic characteristics under different conditions of increasing speed during start-up are demonstrated by comparison with transient nodal *** presented model provides a complete foundation for further investigation of the dynamics of dual rotor systems.

关键词： Dual rotor system Critical speed Transient response Finite element method(FEM)

Optical soliton in a one-dimensional array of a metal nanoparticle-microcavity complex

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Communications in Theoretical Physics 2021年第11期73卷 108-115页

作者： Ning ji Tao shui Yi-Lou Liu Wang-Rui Zhang xiu-Mei Chen Wen-Xing Yang School of Physics and Optoelectronic Engineering Yangtze UniversityJingzhou434023China

Quantum coherence can be enhanced by placing metal nanoparticles(MNPs)in optical *** localized-surface plasmon resonances(LSPRs),nonlinear interaction between the LSPR and microcavity arrays of a MNP-microcavity complex offer a unique playground to observe novel optical phenomena and develop novel concepts for quantum *** we theoretically demonstrate that optical solitons are achievable with a one-dimensional array which consists of a chain of periodically spaced identical MNP-microcavity complex *** differ from the solitons which stem from the MNPs with nonlinear Kerr-like response;the optical soliton here originates from LSPR-microcavity *** experimentally achievable parameters,we identify the conditions under which the nonlinearity induced by LSPR-microcavity interaction allows us to compensate for the dispersion caused by photon hopping of adjacent *** interestingly,the dynamics of solitons can be modulated by varying the radius of the *** presented results illustrate the potential to utilize the MNP-microcavity complex for light manipulation,as well as to guide the design of photon switch and on-chip photon architecture.

关键词： nanoparticle-microcavity Hamiltonian structures soliton and rational solutions

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用激光引发热反射栅方法测量固体热扩散率

物理实验 2004年第9期24卷 9-12,23页

作者：赵超先罗爱华张淑仪张仲宁水修基南京大学近代声学国家重点实验室

阐述了用脉冲激光引发瞬态热反射栅的方法来测量固体材料热扩散率的理论、实验装置和实验技术 .给出用该实验方法测得的纯硅和纯铜的热扩散率 ,并与文献数据进行了比较 ,结果表明该方法是一种适用于不透明固体材料热扩散率测量的无损。

关键词：热反射栅热扩散率衍射脉冲激光材料热学

The Existence of Semiclassical States for Some P-Laplacian Equation with Critical Exponent

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Acta Mathematicae Applicatae Sinica 2017年第2期33卷 417-434页

作者： ji-xiu WANG School of Mathematics and Computer Science Hubei University of Arts and Science Xiangyang 441053 China

In this paper, we study the existence of semiclassical states for some p-Laplacian equation. Under given conditions and minimax methods, we show that this problem has at least one positive solution provided that ε≤ε; for any m ∈ N, it has m pairs solutions if ε≤εm, where ε,εm are sufficiently small positive numbers. Moreover, these solutions axe closed to zero in W1,p（RN） as ε→0.

关键词： semiclassical states positive solutions critical exponent

Plant metabolomics for studying the effect of two insecticides on comprehensive constituents of Lonicerae Japonicae Flos

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Chinese Journal of Natural Medicines 2021年第1期19卷 70-80页

作者： PAN Hui-Qin ZHOU Heng MIAO shui GUO De-An ZHANG Xiao-Li HU Qing MAO xiu-Hong ji Shen NMPA Key Laboratory for Quality Control of Traditional Chinese Medicine Shanghai Institute for Food and Drug ControlShanghai 201203China Shanghai Research Center for Modernization of Traditional Chinese Medicine National Engineering Laboratory for TCM Standardization TechnologyShanghai Institute of Materia MedicaChinese Academy of SciencesShanghai 201203China Shanghai Kaibao Pharmaceutical Co. Ltd.Shanghai 201401China

Pesticides'overuse and misuse have been reported to induce ingredient variations in herbal medicine,which is now gaining attention in the medicinal field as a form of alternative *** date,available studies on pesticide-induced ingredient variations of herbal medicine are limited only on a few compounds and remain most others *** this study,a plant metabolomics-based strategy was performed to systematically explore the effects of two frequently used insecticides on the comprehensive constituents of Lonicerae Japonicae Flos(LJF),the flower buds of Lonicera japonica Thunb..Field trials were designed on a cultivating plot of *** with controls and treatments of imidacloprid(IMI)and compound flonicamid and acetamiprid(CFA).Unbiased metabolite profiling was conducted by ultra-high performance liquid chromatography/quadrupole-Orbitrap mass *** data pretreatment by automatic extraction and screening,a data matrix of metabolite features was submitted for statistical ***,29 metabolic markers,including chlorogenic acids,iridoids and organic acid-glucosides were obtained and *** relative quantitative assay was subsequently performed to monitor their variations across flowering *** is the first study that systematically explored the insecticide-induced metabolite variations of LJF while taking into account the inherent variability of flowering *** results were beneficial for holistic quality assessment of LJF and significant for guiding scientific use of pesticides in the large-scale cultivation.

关键词： Plant metabolomics Insecticide Metabolite variation Lonicerae Japonicae Flos