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冻干A+C群脑膜炎球菌结合疫苗的安全性和免疫原性

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中国生物制品学杂志 2010年第8期23卷 878-880,884页

作者：时念民屈燕艾星庞润田白云骅杨立清吴疆北京市朝阳区疾病预防控制中心北京100021 包头市九原区疾病预防控制中心内蒙古包头014060 北京市疾病预防控制中心北京100013

目的观察冻干A+C群脑膜炎球菌结合疫苗的安全性和免疫原性。方法遵循随机、对照、盲法的原则,选择6～9月龄和≥3岁人群,分别接种观察组(冻干A+C群脑膜炎球菌多糖结合疫苗)和对照组(6～9月龄:A群脑膜炎球菌多糖疫苗;≥3岁:对照A+C群脑膜... 详细信息

目的观察冻干A+C群脑膜炎球菌结合疫苗的安全性和免疫原性。方法遵循随机、对照、盲法的原则,选择6～9月龄和≥3岁人群,分别接种观察组(冻干A+C群脑膜炎球菌多糖结合疫苗)和对照组(6～9月龄:A群脑膜炎球菌多糖疫苗;≥3岁:对照A+C群脑膜炎球菌多糖疫苗)疫苗,观察接种反应、血清抗体含量及抗体阳转率。结果免疫后6～9月龄观察组和对照组全身反应总发生率分别为1.67%和4.58%,局部反应总发生率分别为0.83%和2.08%;≥3岁观察组和对照组全身反应总发生率分别为2.50%和3.33%,局部反应总发生率均为0.83%。6～9月龄观察组和对照组免后A群抗体含量分别为22.27和3.61μg/ml,抗体阳转率分别为99.01%和66.67%,两组差异有统计学意义(P0.05)。结论冻干A+C群脑膜炎球菌结合疫苗在6～9月龄组与3岁及以上组人群中接种具有良好的安全性和免疫原性。

关键词：奈瑟球菌,脑膜炎,血清A群奈瑟球菌,脑膜炎,血清C群结合疫苗安全性免疫原性

北京市朝阳区健康人群水痘-带状疱疹病毒抗体水平调查

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中国生物制品学杂志 2017年第5期30卷 509-513页

作者：董彦宏时念民李丽张馨月和彦苓张军楠包头医学院内蒙古包头014040 北京市朝阳区疾病预防控制中心北京100021

目的调查北京市朝阳区健康人群血清中水痘-带状疱疹病毒(varicella-zoster virus,VZV)抗体水平,为带状疱疹防控策略的制定提供流行病学数据。方法采用城乡分层随机抽样的方法,于2016年5月在北京市朝阳区6个社区31~70岁健康人群中抽取32... 详细信息

目的调查北京市朝阳区健康人群血清中水痘-带状疱疹病毒(varicella-zoster virus,VZV)抗体水平,为带状疱疹防控策略的制定提供流行病学数据。方法采用城乡分层随机抽样的方法,于2016年5月在北京市朝阳区6个社区31~70岁健康人群中抽取320人作为调查对象,采用ELISA法检测每名调查对象血清中VZV-Ig G抗体水平,利用SPSS 17.0软件对数据进行统计学分析。结果 320份血清样本中,VZV-Ig G抗体阳性309人,阳性率为96.56%,抗体平均浓度为(1092.48±4.73)m IU/ml。除66~70岁年龄组健康人群的VZV-Ig G抗体阳性率明显低于其他各年龄组(P0.05);各年龄组不同性别健康人群VZV-Ig G抗体阳性率差异也无统计学意义(均P>0.05);61~65岁年龄组健康男性人群和51~55岁年龄组健康女性人群VZV-Ig G抗体平均浓度最高,分别为(2 405.56±3.75)和(1 683.77±3.46)m IU/ml;城区和乡区健康人群VZV-Ig G抗体阳性率和抗体平均浓度差异均无统计学意义(P>0.05)。结论北京市朝阳区31~70岁健康人群血清中VZV-Ig G抗体阳性水平较高,提示北京市朝阳区健康人群带状疱疹防控形势严峻。

关键词：水痘-带状疱疹病毒健康人群抗体水平

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先天性心脏病儿童预防接种安全性分析

中国生物制品学杂志 2018年第10期31卷 1126-1129页

作者：郑东旖刘兆秋马松张爱玲张文静时念民清华大学第一附属医院北京100016 包头医学院内蒙古包头100041 北京生物制品研究会北京100021

目的探讨先天性心脏病儿童预防接种的安全性。方法选取2013年7月至2017年7月于清华大学第一附属医院进行预防接种的先天性心脏病患儿共69例,以当日相同社区、同一性别、接种同类疫苗儿童作为安全性观察对照样本,进行疫苗接种后安全性主... 详细信息

目的探讨先天性心脏病儿童预防接种的安全性。方法选取2013年7月至2017年7月于清华大学第一附属医院进行预防接种的先天性心脏病患儿共69例,以当日相同社区、同一性别、接种同类疫苗儿童作为安全性观察对照样本,进行疫苗接种后安全性主动监测的调查分析。结果 69例先天性心脏病患儿中,15例手术治疗后愈合以及54例未手术自愈或未自愈患儿,均于不同时期进行疫苗接种后,仅8例患儿出现不良反应,其中5例经判断与疫苗接种无关,且8例接种者均在24 h内恢复正常。与对照组相比,两组反应发生率差异无统计学意义(P>0.05)。结论先天性心脏病儿童在心功能正常及机体健康情况下进行预防接种,不良反应发生率较低,安全性较高。

关键词：先天性心脏病儿童预防接种安全性

Effect of a rigid structure on the dynamics of a bubble beneath the free surface

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Theoretical & Applied Mechanics Letters 2021年第6期11卷 355-361页

作者： shi-min Li A-Man Zhang nian-nian Liu College of shipbuilding Engineering Harbin Engineering UniversityHarbin 150001China

The coupling effect between a pulsating bubble and a free surface near a rigid structure is a complicated physical *** this study,the evolution of an underwater explosion bubble and the free surface near a rigid structure is modeled by the boundary integral *** approach of“double-node method”is used to maintain the stability of fluid-structure junction in the simulations,and meshes on the free surface and the structure are transformed to an open domain to ensure the calculation accuracy and *** are conducted against an underwater explosion experiment near a rigid *** a result,the simulations trace the jetting behavior of the bubble and the rise of the free ***,the bubble migration and the height of the free surface for different structure draughts are analyzed.

关键词： Underwater explosion Bubble dynamics Boundary integral method

北京市朝阳区已生育女性医务人员HPV疫苗认知情况分析

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中国健康教育 2018年第7期34卷 655-658页

作者：张馨月时念民芦强李丽张彦利张文静李淑萍和彦苓内蒙古科技大学包头医学院公共卫生学院内蒙古包头014060 北京市朝阳区人才服务中心卫生人才分中心北京100021 北京市朝阳区疾病预防控制中心生物制品科北京100021

目的了解北京市朝阳区已生育女性医务人员对人乳头瘤病毒(HPV)及其疫苗的认知程度和接种意愿,并探讨其影响因素。方法2017年4-6月,在北京市朝阳区辖区内基层社区卫生服务中心,以分层整群随机抽样法,对536名在职已生育女性医务人员进行... 详细信息

目的了解北京市朝阳区已生育女性医务人员对人乳头瘤病毒(HPV)及其疫苗的认知程度和接种意愿,并探讨其影响因素。方法2017年4-6月,在北京市朝阳区辖区内基层社区卫生服务中心,以分层整群随机抽样法,对536名在职已生育女性医务人员进行自填式问卷调查。结果共调查医务人员536名,其中64.55%的医务人员知道HPV疫苗,文化程度(χ2=15.127,P=0.001)、家庭年收人(χ2=9.923,P=0.007)是影响HPV疫苗知晓率的主要因素。67.20%受调查者愿意接种该疫苗,其中80.64%认为接种疫苗可以保护自己预防宫颈癌;61.94%医务人员愿意为其子女接种HPV疫苗,其中其孩子为女孩的医务人员疫苗接种的意愿更强(χ2=20.979,P<0.001)。妨碍HPV疫苗接种的主要原因为相关知识普及率低、医务人员本身可能仍对疫苗安全性、有效性存在顾虑。结论基层医务人员对HPV及其疫苗知识缺乏系统性了解,应根据不同的专业差异制定相应宣教计划,以提高医务工作者整体水平。

关键词：人乳头瘤病毒疫苗医务人员认识影响因素

Optimal Scheduling of Distribution System with Edge Computing and Data-driven Modeling of Demand Response

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Journal of Modern Power Systems and Clean Energy 2022年第4期10卷 989-999页

作者： Jianpei Han nian Liu Jiaqi shi State Key Laboratory of Alternate Electrical Power System with Renewable Energy Sources North China Electric Power UniversityBeijing 102206China

High penetration of renewable energies enlarge the peak-valley difference of the net load of the distribution system,which puts forward higher requirements for the operation scheduling of the distribution *** the perspective of leveraging demand-side adjustment capabilities,an optimal scheduling method of the distribution system with edge computing and data-driven modeling of price-based demand response(PBDR)is *** introducing the edge computing paradigm,a collaborative interaction framework between the control center and the edge nodes is designed for the optimization of the distribution *** the edge nodes,a classified XGBoost-based PBDR modeling method is proposed for large-scale differentiated *** the control center,a two-stage optimization method integrating pre-scheduling and re-scheduling is proposed based on demand response results from all edge *** the information interaction between the control center and edge nodes,the optimized scheduling of the distribution system with large-scale users is ***,a case study is implemented on the modified IEEE 33-node system,which verifies that the proposed classified modeling method has lower errors,and it is beneficial to improve the economics of the system ***,the simulation results show that the application of edge computing can significantly reduce the calculation time of the optimal scheduling problem with PBDR modeling of large-scale users.

关键词： Demand response distribution system edge computing optimal scheduling XGBoost

Synthesis of the Complex Fluoride LiBaF_(3) through a Solvothermal Process

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Chinese Chemical Letters 2002年第10期13卷 1021-1024页

作者： Rui nian HUA Zhi Hong JIA De min XIE Chun Shan shi Faculty of Chemistry Northeast Normal UniversityChangchun 130024 Key Laboratory of Rare Earth Chemistry and Physics Changchun Institute of Applied ChemistryChinese Academy of SciencesChangchun 130022

The complex fluoride LiBaF3 is solvothermally synthesized at 180degreesC and characterized by means of X-ray powder diffraction, scanning electron microscopy, thermogravimetric analysis and infrared spectroscopy. In the solvothermal process, the solvents, mole ratios of initial mixtures and reaction temperature play important roles in the growth of the single crystal.

关键词： Solvothermal synthesis complex fluoride.

Low-temperature chlorination roasting technology for the simultaneous recovery of valuable metals from spent LiCoO_(2)cathode material

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International Journal of minerals,Metallurgy and Materials 2025年第1期32卷 80-91页

作者： Junjie shi Changle Hou Jingjing Dong Dong Chen Jianzhong Li Key Laboratory for Ecological Metallurgy of Multimetallic mineral(ministry of Education) Northeastern UniversityShenyang 110819China School of Metallurgy Northeastern UniversityShenyang 110819China

With the continuous increase in the disposal volume of spent lithium-ion batteries(LIBs),properly recycling spent LIBs has become essential for the advancement of the circular *** study presents a systematic analysis of the chlorination roasting kinetics and proposes a new two-step chlorination roasting process that integrates thermodynamics for the recycling of LIB cathode *** activation energy for the chloride reaction was 88.41 kJ/mol according to thermogravimetric analysis–derivative thermogravimetry data obtained by using model-free,model-fitting,and Z(α)function(αis conversion rate).Results indicated that the reaction was dominated by the first-order(F1)model when the conversion rate was less than or equal to 0.5 and shifted to the second-order(F2)model when the conversion rate exceeded *** conditions were determined by thoroughly investigating the effects of roasting temperature,roasting time,and the mass ratio of NH_(4)Cl to LiCoO_(2).Under the optimal conditions,namely 400℃,20 min,and NH_(4)Cl/LiCoO_(2)mass ratio of 3:1,the leaching efficiency of Li and Co reached 99.43% and 99.05%,*** of the roasted products revealed that valuable metals in LiCoO_(2)transformed into CoCl_(2) and ***,the reaction mechanism was elucidated,providing insights for the establishment of a novel low-temperature chlorination roasting technology based on a crystal structure *** technology can guide the development of LIB recycling processes with low energy consumption,low secondary pollution,high recovery efficiency,and high added value.

关键词： spent lithium-ion battery thermodynamics chlorination roasting kinetics circular economy

Tribo-informatics:Concept,architecture,and case study

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Friction 2021年第3期9卷 642-655页

作者： Zhinan ZHANG nian YIN shi CHEN Chengliang LIU Stake Key Laboratory of Mechanical System and Vibration Shanghai Jiao Tong UniversityShanghai 200240China School of Mechanical Engineering Shanghai Jiao Tong UniversityShanghai 200240China

Friction plays a vital role in energy dissipation,device failure,and even energy supply in modern *** years of research,data and information on tribology research are becoming increasingly *** of the strong systematic and multi-disciplinary coupling characteristics of tribology,tribology information is scattered in various disciplines with different patterns,e.g.,technical documents,databases,and papers,thereby increasing the information entropy of the system,which is inconducive to the preservation and circulation of research *** the development of computer and information science and technology,many subjects have begun to be combined with information technology,and multi-disciplinary informatics has been *** paper describes the combination of information technology with tribology research,presenting the connotation and architecture of tribo-informatics,and providing a case study on implementing the proposed concept and *** proposal and development of tribo-informatics described herein will improve the research efficiency and optimize the research process of tribology,which is of considerable significance to the development of this field.

关键词： tribo-informatics database tribology information technology