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2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents

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science Bulletin 2018年第23期63卷 1558-1564页

作者： Cheng Wang Yaqi li ying liao Hong Tian Min huang Xiangyu Dong lin Shi Jinghui Sun Hongfang Jin Junbao Du Jindou An Jie Chen Mingwu Chen Qi Chen Sun Chen Yonghong Chen Zhi Chen Adolphus Kai-tung Chau Junbao Du Zhongdong Du Junkai Duan Hongyu Duan Xiangyu Dong lin Feng lijun Fu Fangqi Gong Yonghao Gui ling Han Zhenhui Han Bing He Zhixu He Xiufen Hu yimin hua Guoying huang Min huang Ping huang Yujuan huang Hongfang Jin Mei Jin Bo li Fen li Tao li Xiaohui li Xiaoyan liu yan li Haitao Lv Tiewei Lv Zipu li Luyi Ma Silin Pan Yusheng Pang hua Peng Yuming Qin Jie shen lin Shi Kun Sun Jinghui Sun Hong Tian Jie Tian Cheng Wang Hong Wang Lei Wang Jinju Wang Wendi Wang Yuli Wang rongzhou Wu Tianhe Xia yanyan Xiao Chunhong Xie yanlin Xing Zhenyu Xiong Baoyuan Xu yi Xu Hui yan Shiwei yang Qijian yi Xia Yu Xianyi Yu Yue Yuan Hongyan Zhang Huili Zhang li Zhang Qingyou Zhang Xi Zhang yanmin Zhang Zhiwei Zhang Cuifen zhao Bin Zhou hua zhu Department of Pediatric Cardiovasoloy Children's Medical CenterThe Second Xiangya HospitalCentral South UniversityChangsha 410071China Department of Pediatrics Peking University First HospitalBeijing 100034China Department of Pediatric Cardiology Children's Hospital of Fudan UniversityShanghai 201102China Department of Pediatric Cardiology Shanghai Children's HospitalShanghai 207102China of Pediatrics the 2nd Hospital of Lanzhou UniversityLanzhou 730020China Department of Pediatric Cardiology Capital Institute of PediatricsBezjing 100020China Department of Pediatrics Jilin University First HospitalChangchun 130021China Chinese Pediatric Cardiology Society Chinese Pediatric Society(CPCS)Chinese Medical Association(CMA)China Committee on Pediatric Syncope Pediatricians BranchChinese Medical Doctor Association(CMDA)China Pediatric Cardiology Society Beijing Pediatric SocietyBeijing Medical Association(BMA)China Committee on Pediatric Cardiology Chinese College of Cardiovascular PhysiciansChinese Medical Doctor Association(CMDA)China

Syncope belongs to the transient loss of consciousness(TLOC), characterized by a rapid onset, short duration, and spontaneous complete recovery. It is common in children and adolescents, accounting for 1% to 2% of emergency department *** syncope can seriously affect children's physical and mental health, learning ability and quality of life and sometimes cardiac syncope even poses a risk of sudden death. The present guideline for the diagnosis and treatment of syncope in children and adolescents was developed for guiding a better clinical management of pediatric syncope. Based on the globally recent development and the evidence-based data in china, 2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents was jointly prepared by the Pediatric Cardiology Society, Chinese Pediatric Society, Chinese Medical Association(CMA)/Committee on Pediatric Syncope, Pediatricians Branch, Chinese Medical Doctor Association(CMDA)/Committee on Pediatric Cardiology, Chinese College of Cardiovascular Physicians, Chinese Medical Doctor Association(CMDA)/Pediatric Cardiology Society, Beijing Pediatric Society, Beijing Medical Association(BMA). The present guideline includes the underlying diseases of syncope in children and adolescents, the diagnostic procedures, methodology and clinical significance of standing test and headup tilt test, the clinical diagnosis vasovagal syncope, postural orthostatic tachycardia syndrome, orthostatic hypotension and orthostatic hypertension, and the treatment of syncope as well as follow-up.

关键词： CPCS Children Adolescent syncope

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The first data release(DR1) of the LAMOST regular survey

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Research in Astronomy and Astrophysics 2015年第8期15卷 1095-1124页

作者： A-li Luo Yong-Heng zhao Gang zhao li-Cai Deng Xiao-Wei liu yi-Peng Jing Gang Wang Hao-Tong Zhang Jian-rong Shi Xiang-Qun Cui Yao-Quan Chu Guo-Ping li Zhong-Rui Bai Yue Wu yan Cai Shu-Yun Cao Zi-huang Cao Jeffrey L.Carlin Hai-Yuan Chen Jian-Jun Chen Kun-Xin Chen li Chen Xue-Lei Chen Xiao-yan Chen ying Chen Norbert Christlieb Jia-Ru Chu Chen-Zhou Cui yi-Qiao Dong Bing Du Dong-Wei Fan Lei Feng Jian-Ning Fu Peng Gao Xue-Fei Gong Bo-Zhong Gu yan-Xin Guo Zhan-Wen Han Bo-liang He Jin-liang Hou Yong-Hui Hou Wen Hou Hong-zhuan Hu Ning-{4.g Hu Zhong-Wen Hu Zhi-ying Huo Lei Jia Fang-hua Jiang Xiang Jiang Zhi-Bo Jiang Ge Jin Xiao Kong Xu Kong Ya-Juan Lei Ai-hua li Chang-hua li Guang-Wei li Hai-Ning li Jian li Qi li Shuang li Sha-Sha li Xin-Nan li yan li yin-Bi li Ye-Ping li Yuan liang Chien-Cheng lin Chao liu Gen-rong liu Guan-Qun liu Zhi-Gang liu Wen-Zhi Lu Yu Luo yin-Dun Mao Heidi Newberg Ji-Jun Ni zhao-Xiang Qi Yong-Jun Qi Shi-yin {4. Huo-Ming Shi Jing Song yi-Han Song Ding-Qiang Su Hong-Jun Su Zheng-Hong Tang Qing-{4.g Tao Yuan Tian Dan Wang Da-Qi Wang Feng-Fei Wang Guo-Min Wang Hai Wang Hong-Chi Wang Jian Wang Jia-Ning Wang Jian-ling Wang Jian-Ping Wang Jun-Xian Wang Lei Wang Meng-Xin Wang Shou-Guan Wang Shu-Qing Wang Xia Wang Ya-Nan Wang You Wang Yue-Fei Wang You-Fen Wang Peng Wei Ming-Zhi Wei Hong Wu Ke-Fei Wu Xue-Bing Wu Yu-Zhong Wu Xiao-Zheng Xing ling-Zhe Xu Xin-Qi Xu yan Xu Tai-{4.g yan De-hua yang Hai-Feng yang Hui-Qin yang Ming yang Zheng-Qiu Yao Yong Yu Hui Yuan Hai-Bo Yuan Hai-Long Yuan Wei-Min Yuan Chao Zhai En-Peng Zhang hua-Wei Zhang Jian-Nan Zhang li-Pin Zhang Wei Zhang Yong Zhang yan-Xia Zhang Zheng-Chao Zhang Ming zhao Fang Zhou Xu Zhou Jie zhu Yong-Tian zhu Si-Cheng Zou Fang Zuo National Astronomical Observatories Chinese Academy of Sciences Department of Astronomy Peking University Shanghai Astronomical Observatory Chinese Academy of Sciences Nanjing Institute of Astronomical Optics & Technology National Astronomical ObservatoriesChinese Academy of Sciences University of science and Technology of china Department of Physics Applied Physics and AstronomyRensselaer Polytechnic InstituteTroyNY 12180USA Department of Physics and Astronomy Earlham CollegeRichmondIN 47374USA Universitt Heidelberg Zentrum für AstronomieLandessternwarteKnigstuhl 1269117 HeidelbergGermany Department of Astronomy Beijing Normal University Yunnan Observatories Chinese Academy of Sciences Purple Mountain Observatory Chinese Academy of Sciences

The Large sky Area Multi-Object Fiber Spectroscopic Telescope（LAMOST） general survey is a spectroscopic survey that will eventually cover approximately half of the celestial sphere and collect 10 million spectra of stars, galaxies and QSOs. Objects in both the pilot survey and the first year regular survey are included in the LAMOST DR1. The pilot survey started in October 2011 and ended in June 2012, and the data have been released to the public as the LAMOST Pilot Data Release in August 2012. The regular survey started in September 2012, and completed its first year of operation in June 2013. The LAMOST DR1 includes a total of 1202 plates containing 2 955 3.6 spectra, of which 1 790 879 spectra have observed signalto-noise ratio（SNR） ≥ 10. All data with SNR ≥ 2 are formally released as LAMOST DR1 under the LAMOST data policy. This data release contains a total of 2 204.696 spectra, of which 1 94. 3.9 are stellar spectra, 12 082 are galaxy spectra and 5017 are quasars. The DR1 not only includes spectra, but also three stellar catalogs with measured parameters： late A,FGK-type stars with high quality spectra（1 061 918 entries）, A-type stars（100 073.entries）, and M-type stars（121 522 entries）. This paper introduces the survey design, the observational and instrumental limitations, data reduction and analysis, and some caveats. A description of the FITS structure of spectral files and parameter catalogs is also provided.

关键词： techniques: spectroscopic survey—data release—catalog

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Detection of an anti-angina therapeutic module in the effective population treated by a multi-target drug Danhong injection:a randomized trial

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Signal Transduction and Targeted Therapy 2021年第10期6卷 3009-3018页

作者： Jun liu Dan-Dan li Wei Dong Yu-Qi liu {3.g Wu Da-Xuan Tang Fu-Chun Zhang Meng Qiu Qi hua Jing-Yu He Jun li Bai Du Ting-Hai Du lin-lin Niu Xue-Jun Jiang Bo Cui Jiang-Bin Chen {3.g-Gan Wang Hai-rong Wang Qin Yu Jing He yi-lin Mao Xiao-Fang Bin Yue Deng Yu-Dan Tian Qing-hua Han Da-Jin liu li-Qin Duan Ming-Jun zhao Cui-ying Zhang Hai-ying Dai Ze-hua li ying Xiao You-Zhi Hu Xiao-Yu huang Kun Xing Xin Jiang Chao-Feng liu Jing An Feng-Chun li Tao Tao Jin-Fa Jiang ying {3.g Yao-rong Dong Lei Zhang Guang Fu ying li Shu-Wei huang li-Ping Dou Lan-Jun Sun ying-Qiang zhao Jie li Yun Xia Jun liu Fan liu Wen-Jin He ying li Jian-Cong Tan {3.g lin Ya-Bin Zhou Jian-Fei {3.g Guo-Qing Ma Hui-Jun Chen He-Ping liu Zong-Wu liu Jian-Xiong liu Xiao-Jia Luo Xiao-Hong Bin Ya-Nan Yu Hai-Xia Dang Bing li Fei Teng Wang-Min Qiao Xiao-Long zhu Bing-Wei Chen Qi-Guang Chen Chun-Ti shen Yong-{3. Wang Yun-Dai Chen Zhong Wang Institute of Basic Research in Clinical Medicine China Academy of Chinese Medical SciencesBeijingChina Department of Cardiology Chinese PLA General HospitalBeijingChina Department of Cardiology Dongfang Hospital Affiliated to Beijing University of Chinese MedicineBeijingChina Department of Geratology Peking University Third HospitalBeijingChina Department of Cardiology Xuan Wu HospitalCapital Medical UniversityBeijingChina Department of Cardiology Guang'anmen HospitalChina Academy of Chinese Medical SciencesBeijingChina Department of Cardiology First Affiliated Hospital of Henan University of Chinese MedicineZhengzhouHenanChina Department of Cardiology Wuhan University Renmin HospitalWuhanHubeiChina Department of Cardiology Wuhan University Zhongnan HospitalWuhanHubeiChina Affiliated Zhongshan Hospital of Dalian University DalianLiaoningChina Department of Cardiology Second Affiliated Hospital to Hunan University of Chinese MedicineChangshaHunanChina Department of Cardiology First Affiliated Hospital to Changchun University of Chinese MedicineChangchunJilinChina Department of Cardiology First Affiliated Hospital to Shanxi Medical UniversityTaiyuanShanxiChina Department of Cardiology Affiliated Hospital of Shanxi University of Chinese MedicineXianyangShanxiChina Department of Cardiology Changsha Central HospitalChangshaHunanChina Department of Cardiology Hubei Provincial Hospital of Traditional Chinese MedicineWuhanHubeiChina Department of Cardiology Shanxi Provincial People's HospitalXi'anShanxiChina Department of Cardiology Shanxi Province Hospital of Traditional Chinese MedicineXi'anShanxiChina Department of Cardiology Xi'an City Hospital of Traditional Chinese MedicineXi'anShanxiChina Department of Cardiology Shanghai Tongji HospitalShanghaiChina Department of Cardiology Shanghai Municipal Hospital of Traditional Chinese MedicineShanghaiChina Department of Cardiology The First Hospital of ChangshaChangshaHunanChina Department of Cardiology Xinhua Hospi

It's a challenge for detecting the therapeutic targets of a polypharmacological drug from variations in the responsed networks in thedfferentiated populations with complex diseases,as stable coronary heart ***,in an adaptive,3.-center,randomized,double-blind trial invoving 920 patients with moderate symptomatic stable angina treated by 14.day Danhong injection(DHI),a kind of polyphamacological drug with high quality control,or placebo(0.9%saline),with 76-day following-up,we firstly confrmed that DHl couldincrease the proportion of patients with clinically significant changes on angina-frequency assessed by Seattle Angina Questionnaire(ASAQ-AF220)(12.78%at Day 3.,95%confidence interval[C]5.86-19.71%,P=0.0003.13.82%at Day 6C0,95%CI 6.82-20.82%,P=0.0001and 8.95%at Day 90,95%CI 2.06-15.85%,P=0.01).We also found that there were no significant differences in new-onset major vascularevents(P=0.8502)and serious adverse events(P=0.9105)between DHl and *** performing the RNA sequencing in 62 selectedpatients,we developed a systemic modular approach tp identfy differentilly expressed modules(DEMs)of DHI with the Z_(summay)valueless than 0 compared with the control group,calculated by weighted gene co-expression network analysis(WGCNA),and sketched out thebasic framework on a modular map with 25 functional modules targeted by ***,the effective therapeutic module(ETM),defined as the highest corelation value with the phenotype alteration(SAQ-AF,the change in SAQ-AF at Day 3. from baseline)calculatedby WGCNA,was identifed in the population with the best effect(ASAQ-AF24.),which is related to anticoagulation and regulation ofcholesterol *** assessed the modular flexbility of this ETM using the global topological D value based on Euclidean distance,which is corelated with phenotype alteration(r^(2):0.8204.P=0.019)by linear *** study identified the ant-angina therapeuticmodule in the effective population treated by the multi-target

关键词： angina injection sketch

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2015-2021年CHINET临床分离沙雷菌属细菌耐药性变迁

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中国感染与化疗杂志 2024年第1期24卷 43-52页

作者：李金胡志东杨洋胡付品朱德妹汪复谢轶康梅张朝霞季萍沈瀚周万青刘文恩李艳明俞云松林洁郭大文赵金英徐雪松鄢超徐元宏黄颖徐英春张小江王传清王爱敏王山梅楚亚菲喻华黄湘宁李继红卓超苏丹虹张利侠马娟郭素芳贾伟李刚倪语星孙景勇孙自镛陈中举单斌杜艳褚云卓田素飞汪瑞忠房华金炎邵春红刘江山张泓王春胡云建艾效曼胡芳芳魏莲花邹凤梅朱镭孟晋华胡雪飞段金菊康建邦俞碧霞董芳郑红艳沈继录吴劲松卢月梅赵勇龚萍马晓波郑燕青郭如意朱焱冯佼薛顺虹陈运生孟青顾洪芹温开镇张贻荣周树平周艳王世富廖龙凤姜琳贺雯窦睿岳春雷黄文辉天津医科大学总医院天津300052 复旦大学附属华山医院抗生素研究所四川大学华西医院新疆医科大学第一附属医院南京大学医学院附属鼓楼医院中南大学湘雅医院浙江大学医学院附属邵逸夫医院哈尔滨医科大学附属第一医院吉林大学中日联谊医院安徽医科大学第一附属医院北京协和医院复旦大学附属儿科医院河南省人民医院四川省人民医院河北医科大学第二医院广州医科大学附属第一医院陕西省人民医院内蒙古医科大学附属医院宁夏医科大学总医院上海交通大学医学院附属瑞金医院华中科技大学同济医学院附属同济医院昆明医科大学第一附属医院中国医科大学附属第一医院上海市浦东新区人民医院山东省立医院甘肃省金昌市中西医结合医院上海交通大学附属儿童医院北京医院贵州省人民医院甘肃省人民医院山西省儿童医院南昌大学附属第一医院山西医科大学第二医院浙江省宁波市镇海龙赛医院首都医科大学附属北京儿童医院安徽医科大学附属第四医院深圳市人民医院湖北省秭归县人民医院厦门大学附属第一医院福建省泉州市第一医院四川省邻水县人民医院青海省互助县人民医院深圳儿童医院山东省广饶县人民医院福建省晋江市医院江西省儿童医院山东大学齐鲁儿童医院江西省赣县区人民医院河南省辉县市人民医院辽宁省营口市经济技术开发区中心医院安徽省亳州市利辛县人民医院吉林省九台区人民医院青海省青海大学附属医院

目的了解国内主要地区临床分离沙雷菌属细菌对常用抗菌药物的耐药率及变迁。方法由CHINET中国细菌耐药性监测网参与成员单位将临床分离菌采用纸片扩散法或自动化商业药敏测试系统按CHINET统一技术方案进行仪器法药物敏感性试验。结果201... 详细信息

目的了解国内主要地区临床分离沙雷菌属细菌对常用抗菌药物的耐药率及变迁。方法由CHINET中国细菌耐药性监测网参与成员单位将临床分离菌采用纸片扩散法或自动化商业药敏测试系统按CHINET统一技术方案进行仪器法药物敏感性试验。结果2015年1月—2021年12月从我国不同地区53.医院临床分离到的沙雷菌属17226株。分离的菌株数从2015年959株上升到2021年3.88株,自门急诊患者中分离到的沙雷菌占7.3.(1265/17226),住院患者菌株占92.7%(15961/17226)。17226株沙雷菌属细菌中呼吸道标本占比最高(57.5%±2.5%),其次为血液标本(11.5%±1.5%)。7年连续监测发现除氨苄西林、头孢唑林及呋喃妥因外其他抗菌药物细菌耐药率均有所下降,亚胺培南和美罗培南虽然耐药率数值有所反复,但仍从8.1%和8.3.降到5.3.和5.2%。成年患者来源的菌株对头孢哌酮-舒巴坦、头孢他啶-阿维巴坦、头孢噻肟、亚胺培南、呋喃妥因和替加环素耐药率三级医院高于二级医院,其他抗菌药物耐药率均低于二级医院。分离自儿童患者的沙雷菌对头孢哌酮-舒巴坦、哌拉西林-他唑巴坦、阿米卡星、甲氧苄啶-磺胺甲唑和替加环素的耐药率低于5%。分离自ICU的菌株对抗菌药物的耐药率普遍高于其他监测科室。7年监测碳青霉烯类耐药肠杆菌目菌株检出率为8.2%。结论7年中沙雷菌属细菌耐药率呈缓慢下降趋势,继续加强标本及时送检及合理使用抗菌药物对细菌耐药率下降起着尤为重要的作用,落实医院感染控制可有效降低耐药细菌的发生。

关键词：沙雷菌属抗菌药物细菌耐药性监测

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Amplitude analysis of the decays D^(0)→π^(+)π^(−)π^(+)π^(−)and D^(0)→π^(+)π^(−)π^(0)π^(0)

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Chinese Physics C 2024年第8期48卷 6-33页

作者： M.Ablikim M.N.Achasov P.Adlarson O.Afedulidis X.C.Ai R.Aliberti A.Amoroso Q.An Y.Bai O.Bakina I.Balossino Y.Ban H.-R.Bao V.Batozskaya K.Begzsuren N.Berger M.Berlowski M.Bertani D.Bettoni F.Bianchi E.Bianco A.Bortone I.Boyko R.A.Briere A.Brueggemann H.Cai X.Cai A.Calcaterra G.F.Cao N.Cao S.A.Cetin J.F.Chang W.L.Chang G.R.Che G.Chelkov C.Chen C.H.Chen Chao Chen G.Chen H.S.Chen M.L.Chen S.J.Chen S.L.Chen S.M.Chen T.Chen X.R.Chen X.T.Chen Y.B.Chen Y.Q.Chen Z.J.Chen Z.Y.Chen S.K.Choi X.Chu G.Cibinetto F.Cossio J.J.Cui H.L.Dai J.P.Dai A.Dbeyssi R.E.de Boer D.Dedovich C.Q.Deng Z.Y.Deng A.Denig I.Denysenko M.Destefanis F.De Mori B.Fang S.S.Fang W.X.Fang Y.Fang Y.Q.Fang R.Farinelli L.Fava F.Feldbauer G.Felici C.Q.Feng J.H.Feng Y.T.Feng K.Fischer M.Fritsch C.D.Fu J.L.Fu Y.W.Fu H.Gao Y.N.Gao yang Gao S.Garbolino I.Garzia P.T.Ge Z.W.Ge C.Geng E.M.Gersabeck B.Ding X.X.Ding Y.Ding Y.Ding J.Dong L.Y.Dong M.Y.Dong X.Dong M.C.Du S.X.Du Z.H.Duan P.Egorov Y.H.Fan J.Fang JA.Gilman K.Goetzen L.Gong W.X.Gong W.Gradl S.Gramigna M.Greco M.H.Gu Y.T.Gu C.Y.Guan Z.L.Guan A.Q.Guo L.B.Guo M.J.Guo R.P.Guo Y.P.Guo A.Guskov J.Gutierrez K.L.Han T.T.Han X.Q.Hao F.A.Harris K.K.He K.L.He F.H.Heinsius C.H.Heinz Y.K.Heng C.Herold T.Holtmann P.C.Hong G.Y.Hou X.T.Hou Y.R.Hou Z.L.Hou B.Y.Hu H.M.Hu J.F.Hu T.Hu Y.Hu G.S.huang K.X.huang L.Q.huang X.T.huang Y.P.huang T.Hussain F.H\"olzken N.H\"usken N.in der Wiesche M.Irshad J.Jackson S.Janchiv J.H.Jeong Q.Ji Q.P.Ji W.Ji X.B.Ji X.L.Ji Y.Y.Ji X.Q.Jia Z.K.Jia D.Jiang H.B.Jiang P.C.Jiang S.S.Jiang T.J.Jiang X.S.Jiang Y.Jiang J.B.Jiao J.K.Jiao Z.Jiao S.Jin Y.Jin M.Q.Jing X.M.Jing T.Johansson S.Kabana N.Kalantar-Nayestanaki X.L.Kang X.S.Kang M.Kavatsyuk B.C.Ke V.Khachatryan A.Khoukaz R.Kiuchi O.B.Kolcu B.Kopf M.Kuessner X.Kui A.Kupsc W.K\"uhn J.J.Lane P.Larin L.Lavezzi T.T.Lei Z.H.Lei H.Leithoff M.Lellmann T.Lenz C.li C.li C.H.li Cheng li D.M.li F.li G.li H.li H.B.li H.J.li H.N.li Hui li J.R.li J.S.li K.li L.J.li L.K.li Lei li M.H.li P.R.li Q.M.li Q.X.li R.li S.X.li T.li W.D.li W.G.li X.li X.H.li X.L.li X.Y.li Y Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China Beihang University Beijing 100191China Bochum Ruhr-University D-44780 BochumGermany Budker Institute of Nuclear Physics SB RAS(BINP) Novosibirsk 630090Russia Carnegie Mellon University PittsburghPennsylvania 15213USA Central china Normal University Wuhan 430079China Central South University Changsha 410083China china Center of Advanced science and Technology Beijing 100190China china University of Geosciences Wuhan 430074China Chung-Ang University Seoul06974Republic of Korea COMSATS University Islamabad Lahore CampusDefence RoadOff Raiwind Road54000 LahorePakistan Fudan University Shanghai 200433China GSI Helmholtzcentre for Heavy Ion Research GmbH D-64291 DarmstadtGermany Guangxi Normal University Guilin 541004China Guangxi University Nanning 530004China Hangzhou Normal University Hangzhou 310036China Hebei University Baoding 071002China Helmholtz Institute Mainz Staudinger Weg 18D-55099 MainzGermany Henan Normal University Xinxiang 453007China Henan University Kaifeng 475004China Henan University of science and Technology Luoyang 471003China Henan University of Technology Zhengzhou 450001China huangshan College Huangshan 245000China Hunan Normal University Changsha 410081China Hunan University Changsha 410082China Indian Institute of Technology Madras Chennai 600036India Indiana University BloomingtonIndiana 47405USA INFN Laboratori Nazionali di Frascati INFN Laboratori Nazionali di FrascatiI-00044FrascatiItaly INFN Laboratori Nazionali di Frascati INFN Sezione di PerugiaI-06100PerugiaItaly INFN Laboratori Nazionali di Frascati University of PerugiaI-06100PerugiaItaly INFN Sezione di Ferrara INFN Sezione di FerraraI-44122FerraraItaly INFN Sezione di Ferrara University of FerraraI-44122FerraraItaly Inner Mongolia University Hohhot 010021China Institute of Modern Physics Lanzhou 730000China Institute of Physics and Technology Peace Avenue 54BUlaanbaatar 13330Mongolia Instituto de A

Using e^(+)e^(−)annihilation data corresponding to an integrated luminosity of 2.93.fb^(−1)taken at the center-of-mass energy√s=3.773.GeV with the BESIII detector,a joint amplitude analysis is performed on the decays D^(0)→π^(+)π^(−)π^(+)π^(−)and D^(0)→π^(+)π^(−)π^(0)π^(0)(non-η).The fit fractions of individual components are obtained,and large interferences among the dominant components of the decays D^(0)→a_(1)(1260)π,D^(0)→π(13.0)π,D^(0)→ρ(770)ρ(770),and D^(0)→2(ππ)_(S)are observed in both *** the obtained amplitude model,the CP-even fractions of D^(0)→π^(+)π^(−)π^(+)π^(−)and D^(0)→π^(+)π^(−)π^(0)π^(0)(non-η)are determined to be(75.2±1.1_(stat).±1.5_(syst.))%and(68.9±1.5_(stat).±2.4.(syst.))%,*** branching fractions of D^(0)→π^(+)π^(−)π^(+)π^(−)and D^(0)→π^(+)π^(−)π^(0)π^(0)(non-η)are measured to be(0.688±0.010_(stat.)±0.010_(syst.))%and(0.951±0.025_(stat.)±0.021_(syst.))%,*** amplitude analysis provides an important model for the binning strategy in measuring the st{3. phase parameters of D^(0)→4.when used to determine the CKM angleγ(ϕ_(3.)via the B^(−)→DK^(−)decay.

关键词： BESIII D^(0)meson decays amplitude analysis CP-even fraction

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2015—2021年CHINET临床分离变形杆菌属、摩根菌属和普罗威登菌属细菌耐药性变迁

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中国感染与化疗杂志 2024年第4期24卷 410-417页

作者：许云敏董小雪单斌杨洋胡付品朱德妹徐英春张小江季萍张峰波谢轶康梅王传清付盼徐元宏黄颖孙自镛陈中举倪语星孙景勇褚云卓田素飞胡志东李金俞云松林洁郭素芳魏莲花邹凤梅张泓王春胡云建艾效曼卓超苏丹虹郭大文赵金英喻华黄湘宁刘文恩李艳明金炎邵春红徐雪松鄢超王山梅楚亚菲张利侠马娟周树平周艳朱镭孟晋华董芳郑红艳胡芳芳沈瀚周万青贾伟李刚吴劲松卢月梅李继红段金菊康建邦马晓波郑燕萍郭如意朱焱陈运生孟青王世富胡雪飞沈继录黄文辉汪瑞忠房华俞碧霞赵勇龚萍温开镇张贻荣刘江山廖龙凤顾洪芹姜琳贺雯薛顺虹冯佼岳春雷昆明医科大学第一附属医院检验科昆明650032 复旦大学附属华山医院抗生素研究所北京协和医院新疆医科大学第一附属医院四川大学华西医院复旦大学附属儿科医院安徽医科大学第一附属医院华中科技大学同济医学院附属同济医院上海交通大学医学院附属瑞金医院中国医科大学附属第一医院天津医科大学总医院浙江大学医学院附属邵逸夫医院内蒙古医科大学附属医院甘肃省人民医院上海交通大学医学院附属儿童医院北京医院广州医科大学附属第一医院哈尔滨医科大学附属第一医院四川省人民医院中南大学湘雅医院山东省立医院吉林大学中日联谊医院河南省人民医院陕西省人民医院江西省儿童医院山西省儿童医院首都医科大学附属北京儿童医院贵州省人民医院南京大学医学院附属鼓楼医院宁夏医科大学总医院深圳市人民医院河北医科大学第二医院山西医科大学第二医院厦门大学附属第一医院福建省泉州市第一医院深圳市儿童医院山东大学齐鲁儿童医院南昌大学第一附属医院安徽医科大学第四附属医院青海省青海大学附属医院上海市浦东新区人民医院浙江省宁波市镇海龙赛医院湖北省秭归县人民医院福建省晋江市医院甘肃省金昌市中西医结合医院江西省赣县区人民医院山东省广饶县人民医院河南省辉县市人民医院辽宁省营口市经济技术开发区中心医院青海省互助县人民医院四川省邻水县人民医院吉林省九台区人民医院

目的了解2015年1月1日—2021年12月3.日CHINET耐药监测网变形杆菌属、摩根菌属和普罗威登菌属细菌分布及耐药性变化。方法按CHINET统一方案进行药物敏感性试验。按CLSI M1003.st 2021年版折点标准判断结果。结果7年间共监测收集到肠杆... 详细信息

目的了解2015年1月1日—2021年12月3.日CHINET耐药监测网变形杆菌属、摩根菌属和普罗威登菌属细菌分布及耐药性变化。方法按CHINET统一方案进行药物敏感性试验。按CLSI M1003.st 2021年版折点标准判断结果。结果7年间共监测收集到肠杆菌目摩根菌科细菌3.4.0}株,其中变形杆菌属24.60株,摩根菌属6704.,普罗威登菌属1569株,细菌数量呈增长趋势。标本分布前三位依次为尿液、下呼吸道和伤口分泌物。三种菌属细菌对阿米卡星、美罗培南、头孢西丁、头孢吡肟、头孢哌酮-舒巴坦和哌拉西林-他唑巴坦的耐药率均较低,其中变形杆菌属和摩根菌属对受测试抗菌药物的耐药率大多10%,普罗威登菌属的耐药率大多20%。变形杆菌属、摩根菌属和普罗威登菌属中的碳青霉烯类耐药菌株检出率分别为1.4.、1.9%和15.6%。结论变形杆菌属、摩根菌属和普罗威登菌属临床分离菌株近年有明显增加趋势;这些菌株中碳青霉烯类耐药菌株的检出亦有明显增多。应加强关注,重视细菌耐药监测,合理用药,防止耐药细菌的发生和耐药率上升。

关键词：变形杆菌属摩根菌属普罗威登菌属碳青霉烯类耐药细菌耐药性监测

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云南洱海的生态保护及可持续利用对策

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环境科学 2005年第5期26卷 38-42页

作者：颜昌宙金相灿赵景柱沈兵李宁波黄昌筑熊仲华中国科学院生态环境研究中心系统生态重点实验室北京100085 中国环境科学研究院湖泊生态环境创新基地北京100012 云南大理州环境保护局大理671000

由于湖区经济发展和人口压力的增加,致使洱海出现了富营养化进程加剧、湖泊水位降低、湖滨带生境恶化、生物资源过度开发等一系列的生态环境问题.2002年洱海入湖污染负荷量CODCr为3.08t.a-1,总磷为13..3.t.a-1,总氮为14.6.3.t.a-1,其营... 详细信息

由于湖区经济发展和人口压力的增加,致使洱海出现了富营养化进程加剧、湖泊水位降低、湖滨带生境恶化、生物资源过度开发等一系列的生态环境问题.2002年洱海入湖污染负荷量CODCr为3.08t.a-1,总磷为13..3.t.a-1,总氮为14.6.3.t.a-1,其营养盐负荷总磷和总氮均已超过洱海中营养水平下的环境容量.洱海已处在一个关键的敏感的营养状态转型时期,形势十分严峻,为此提出明确洱海主导功能,注重城市化进程中的产业结构和产业布局的优化调整,建立洱海湖滨带保护区,加强旅游污染控制,适当调整洱海水资源调度运行方式,并通过污水收集与处理工程、主要入湖河流生态修复工程、生态农业建设及农村环境改善工程、湖泊生态修复工程、流域水土保持工程等措施,保护和改善洱海水环境.

关键词：洱海生态保护富营养化可持续利用对策

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2022年CHINET三级医院细菌耐药监测

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中国感染与化疗杂志 2024年第3期24卷 277-286页

作者：郭燕胡付品朱德妹汪复蒋晓飞徐英春张小江张峰波季萍谢轶肖玉玲王传清付盼徐元宏黄颖孙自镛陈中举孙景勇陈庆褚云卓田素飞胡志东李金俞云松林洁单斌许云敏郭素芳王艳艳魏莲花李可可张泓潘芬胡云建艾效曼卓超苏丹虹郭大文赵金英喻华黄湘宁刘文恩李艳明金炎邵春红徐雪松李威王山梅楚亚菲张利侠马娟周树平周艳朱镭孟晋华董方吕志勇胡芳芳沈瀚周万青贾伟李刚吴劲松卢月梅李继红孙倩段金菊康建邦马晓波郑燕青郭如意朱焱陈运生孟青王世富胡雪飞黄文辉李娟石泉贵杨娟热孜瓦古丽·阿不力米提黄莉莉邵雪君任晓艳李冬张群陈雪黎日海徐洁丽高凯杰徐璐林琳张卓刘健龙付敏郭映辉张文超王增国贾凯夏云孙珊杨慧敏苗艳周明明张诗海刘红娟陈楠李婵沈继录门万琪王鹏张晓威刘彦彦安勇复旦大学附属华山医院抗生素研究所国家卫健委抗生素临床药理重点实验室上海200040 北京协和医院新疆医科大学第一附属医院四川大学华西医院复旦大学附属儿科医院安徽医科大学第一附属医院华中科技大学同济医学院附属同济医院上海交通大学医学院附属瑞金医院中国医科大学附属第一医院天津医科大学总医院浙江大学医学院附属邵逸夫医院昆明医科大学第一附属医院内蒙古医科大学附属医院甘肃省人民医院上海交通大学医学院附属儿童医院北京医院广州医科大学附属第一医院哈尔滨医科大学附属第一医院四川省人民医院中南大学湘雅医院山东省立医院吉林大学中日联谊医院河南省人民医院陕西省人民医院江西省儿童医院山西省儿童医院首都医科大学附属北京儿童医院贵州省人民医院南京大学医学院附属鼓楼医院宁夏医科大学总医院深圳市人民医院河北医科大学第二医院山西医科大学第二医院厦门大学附属第一医院福建省泉州市第一医院深圳市儿童医院山东大学齐鲁儿童医院南昌大学第一附属医院青海大学附属医院西藏军区总医院乌鲁木齐市第一人民医院(乌鲁木齐儿童医院) 苏州大学附属儿童医院云南省腾冲市人民医院重庆医科大学附属儿童医院广西桂平市人民医院河南省儿童医院沈阳市儿童医院湖南省儿童医院河北省儿童医院西安市儿童医院重庆医科大学附属第一医院陕西省神木市医院浙江省儿童医院安徽省儿童医院天津市儿童医院安徽医科大学第四附属医院长春市儿童医院邢台市第九医院复旦大学附属华山医院检验科国家卫健委抗生素临床药理重点实验室上海200040

目的监测2022年CHINET三级医院临床分离菌对抗菌药物的敏感性。方法国内58所三级医院临床分离菌采用纸片扩散法或商品化药敏试验自动测试仪按CHINET统一监测技术方案进行抗菌药物敏感性试验。结果按CLSI M1002022年版折点标准判断。结... 详细信息

目的监测2022年CHINET三级医院临床分离菌对抗菌药物的敏感性。方法国内58所三级医院临床分离菌采用纸片扩散法或商品化药敏试验自动测试仪按CHINET统一监测技术方案进行抗菌药物敏感性试验。结果按CLSI M1002022年版折点标准判断。结果收集2022年1月1日-12月3.日上述医院临床分离菌共3.8013.,其中革兰阳性菌占29.5%,革兰阴性菌占70.5%。金黄色葡萄球菌、表皮葡萄球菌和其他凝固酶阴性葡萄球菌(除假中间葡萄球菌和施氏葡萄球菌外)中甲氧西林耐药株的检出率分别为28.3.、76.7%和77.9%。MRSA中有94.0%的菌株对甲氧苄啶-磺胺甲噁唑敏感;MRSE中有90.8%的菌株对利福平敏感,未发现万古霉素耐药株。肠球菌属中粪肠球菌对多数测试抗菌药物的耐药率均显著低于屎肠球菌,两者中均有少数万古霉素耐药株。2022年儿童和成人中分离的非脑膜炎肺炎链球菌中PSSP的检出率分别为94.2%和95.7%。除克雷伯菌属细菌对碳青霉烯类的耐药率范围为21.7%~23.1%外,其他细菌的耐药率多在13.1%以下。除天然耐药菌株外,其他肠杆菌目细菌对替加环素、黏菌素和多黏菌素B高度敏感,耐药率范围为0.1%~13.3.。铜绿假单胞菌对美罗培南的耐药率从2019年的23.5%下降至2022年的18.0%;鲍曼不动杆菌对美罗培南的耐药率亦从2019年的79.0%下降至2022年的72.5%。结论三级医院临床分离菌对常见抗菌药物的耐药率仍呈增长趋势,但碳青霉烯类耐药肺炎克雷伯菌、铜绿假单胞菌、鲍曼不动杆菌等多种重要耐药细菌的检出率近年来呈现连续下降趋势,提示加强细菌耐药监测,开展多学科联动的方式对控制耐药细菌的流行播散是行之有效的。

关键词：三级医院细菌耐药监测药物敏感性试验碳青霉烯类耐药革兰阴性杆菌

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Overview to the Hard X-ray Modulation Telescope (Insight-HXMT) Satellite

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science china(Physics,Mechanics & Astronomy) 2020年第4期63卷 2-19页

作者： Shuang-Nan Zhang TiPei li FangJun Lu liMing Song YuPeng X u CongZhan liu Yong Chen XueLei Cao QingCui Bu Zhi Chang Gang Chen li Chen TianXiang Chen yiBao Chen YuPeng Chen Wei Cui WeiWei Cui JingKang Deng YongWei Dong Yuan Yuan Du MinXue Fu Guanhua Gao He Gao Min Gao MingYu Ge YuDong Gu Ju Guan Can Gungor ChengCheng Guo DaWei Han Wei Hu Yue huang Jia Huo ShuMei Jia Luhua Jiang WeiChun Jiang Jing Jin YongJie Jin Bing li ChengKui li Gang li MaoShun li Wei li Xian li XiaoBo li XuFang li yanGuo li ZiJian li ZhengWei li Xiaohua liang JinYuan liao GuoQing liu HongWei liu ShaoZhen liu XiaoJing liu Yuan liu yiNong liu Bo Lu XueFeng Lu Tao Luo Xiang Ma Bin Meng yi Nang Jianyin Nie Ge Ou JinLu Qu Na Sai RenCheng Shang GuoHong shen liang Sun ying Tan lian Tao Youli Tuo Chen Wang ChunQin Wang GuoFeng Wang huanYu Wang Juan Wang WenShuai Wang YuSa Wang Xiangyang Wen Baiyang Wu BoBing Wu Mei Wu GuangCheng Xiao Shaolin Xiong linli yan JiaWei yang sheng yang yanJi yang QiBin yi Bin Yuan AiMei Zhang ChunLei Zhang ChengMo Zhang Fan Zhang HongMei Zhang Juan Zhang Qiang Zhang shenyi Zhangs Shu Zhang Tong Zhang WanChang Zhang Wei Zhang Wen{54. Zhang yi Zhang yiFei Zhang YongJie Zhang Yue Zhang {54. Zhang Zhi Zhang Ziliang Zhang Haisheng {54. XiaoFan {54. ShiJie Zheng JianFeng Zhou YuXuan zhu Yue zhu Renlin Zhuang Key Laboratory of Particle Astrophysics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University of Chinese Academy of sciences Beijing 100049China Department of Astronomy Tsinghua UniversityBeijing 100084China Department of Physics Tsinghua UniversityBeijing 100084China Department of Astronomy Beijing Normal UniversityBeijing 100088China Department of Engineering Physics Tsinghua UniversityBeijing 100084China National Astronomical Observatories Chinese Academy of SciencesBeijing 100101China National Space science Center Chinese Academy of SciencesBeijing 100190China

As china’s first X-ray astronomical satellite, the Hard X-ray Modulation Telescope (HXMT), which was dubbed as Insight-HXMT after the launch on June 15, 2017, is a wide-band(1-250 ke V) slat-collimator-based X-ray astronomy satellite with the capability of all-sky monitoring in 0.2-3.Me V. It was designed to perform pointing, scanning and gamma-ray burst(GRB)observations and, based on the Direct Demodulation Method (DDM), the image of the scanned sky region can be *** we give an overview of the mission and its progresses, including payload, core sciences, ground calibration/facility, ground segment, data archive, software, in-orbit performance, calibration, background model, observations and some preliminary results.

关键词： X-and γ-ray telescopes and instrumentation neutron stars black holes X-ray binaries γ-ray bursts

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大别山山核桃果实与叶片性状的表型多样性研究

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林业科学研究 2020年第1期33卷 152-161页

作者：张深梅奚建伟洪俊彦夏国华李岩黄兴召朱先富黄坚钦省部共建亚热带森林培育国家重点实验室浙江杭州311300 浙江农林大学林业与生物技术学院浙江杭州311300 安徽农业大学林学与园林学院安徽合肥230036 金寨县富东生态农业开发有限公司安徽六安237000

[目的]探讨大别山山核桃天然种群的表型多样性,为种质资源收集、优选、改良提供理论支持,为大别山山核桃的开发利用奠定基础。[方法]从19个大别山山核桃天然种群中选取198个单株,测定其果实和叶片的表型性状共16个,采用巢式方差分析,单... 详细信息

[目的]探讨大别山山核桃天然种群的表型多样性,为种质资源收集、优选、改良提供理论支持,为大别山山核桃的开发利用奠定基础。[方法]从19个大别山山核桃天然种群中选取198个单株,测定其果实和叶片的表型性状共16个,采用巢式方差分析,单因素方差分析,相关性分析,非加权配对算数平均法(UPGMA)等方法揭示大别山山核桃表型性状与地理分布的关系及其变异规律。[结果](1)大别山山核桃的16个表型性状在种群间和种群内均存在极显著差异(P2)各表型性状的变异范围为1.64.-26.59%,平均变异系数为9.63.;果实表型与叶片表型的种群内平均变异系数分别为6.16%和15.4.%,果实表型平均变异系数较小,性状相对稳定;(3.表型性状间的相关性分析表明,性状间达极显著相关的有60对,达显著相关的11对;(4.种群间和种群内的平均方差分量百分比分别为4..28%和17.53.,平均表型分化系数为66.25%,表明大别山山核桃表型变异主要来自种群间;(5)当距离系数为0.04.,19个种群被分为4.,聚类情况基本与经度的变化一致。

关键词：大别山山核桃种群果实叶片表型变异

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