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The Ruin Probability of the Renewal Model with Constant Interest Force and Upper-tailed Independent Heavy-tailed Claims

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Acta Mathematica Sinica,English Series 2010年第9期26卷 1815-1826页

作者： Xin Mei shen Zheng yan lin Department of Mathematics Zhejiang University Hangzhou 310027 P. R. China

In this paper, we obtain the uniform estimate for discounted aggregate claims in the continuous-time renewal model of upper-tailed independent and heavy-tailed random variables. With constant interest force and constant premium rate, we establish a uniform simple asymptotic formula for ruin probability of the renewal model in the case where the initial surplus is large.

关键词： Asymptotic estimate consistent variation renewal process upper-tail independent

Acute Cerebellar Infarction Complicated with Multiple Intracerebral Hemorrhage Treated by An Integrated Chinese and Western Medicine Approach:A Case Report

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Chinese Journal of Integrative Medicine 2017年第3期23卷 221-225页

作者： CHEN Peng shen Qin-xuan shen lin-yan WU Zhi-bing PI Li-hong GE Wen-hua QI Wei Department of Neurology the First Clinical Medical College of Guangzhou University of Chinese Medicine Guangzhou(510006) China Department of Rehabilitation Medicine the First Affiliated Hospital of Guangzhou Medical University Guangzhou (510006) China

Cerebellar infarction accounts for almost 3%of all ischemic strokes,with 27,400 new cases each year in the USA alone.（1）Since the computerized tomography（CT）scan is often negative in the early hours after onset,it... 详细信息

关键词： computerized cerebellar alone consciousness decoction stasis vomiting intravenous infusion coagulation

Quasi-equality constrained risk-sensitive filtering for nonlinear discrete-time systems

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控制理论与应用（英文版） 2012年第2期10卷 229-235页

作者： linfeng shen, yan lin School of Automation Science and Electrical Engineering, Beijing University of Aeronautics and Astronautics, Beijing 100191, China School of Automation Science and Electrical Engineering Beijing University of Aeronautics and Astronautics Beijing China

More and more data fusion models contain state constraints with valuable information in the filtering process. In this study, an optimal filter of risk sensitive with quasi-equality constraints is formulated using the reference probability method. Through recursion processes of probability density acquired from the probability measure change, the derived algorithm is optimal in the sense of the risk sensitive parameter. The system and constraint models are Consistent in statistics. Simulation results show that it is more robust and efficient than projection filters for the worst-case of noises and model uncertainty.

关键词： Optimal estimation Risk-sensitive filtering Constraints

Coagulase-negative staphylococcus and enterococcus as predominant pathogens in liver transplant recipients with Gram-positive coccal bacteremia

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Chinese Medical Journal 2010年第15期123卷 1983-1988页

作者： SHI Shao-hua KONG Hai-shen JIA Chang-ku XU Jian ZHANG Wen-jin WANG Wei-lin shen yan ZHANG Min ZHENG Shu-sen Department of Hepatobiliary Surgery and Center of Liver Transplantation First Affiliated Hospital Zhejiang University School of Medicine Hangzhou Zhejiang 310003 China

Background Gram-positive bacteria such as Staphylococcus aureus have been a common cause of infection among liver transplant （LT） recipients in recent decades. The understanding of local epidemiology and its evolving trends with regard to pathogenic spectra and antibiotic susceptibility is beneficial to prophylactic and empiric treatment for LT recipients. This study aimed to investigate etiology, timing, antibiotic susceptibility and risk factors for multidrug resistant （MDR） Gram-positive coccal bacteremia after *** A cohort analysis of prospectively recorded data was performed to investigate etiologies, timing, antibiotic susceptibility and risk factors for MDR Gram-positive coccal bacteremia in 475 LT *** In 475 LT recipients in the first six months after LT, there were a total of 98 episodes of bacteremia caused by Gram-positive cocci in 82 （17%） patients. Seventy-five （77%） bacteremic episodes occurred in the first post-LT *** most frequent Gram-positive cocci were methicillin-resistant coagulase-negative staphylococcus （CoNS, 46 isolates）,methicillin-resistant Staphylococcus aureus （MRSA, 13） and enterococcus （34, E. faecium 30, E. faecalis 4）. In all Gram-positive bacteremic isolates, 59 of 98 （60%） were MDR. Gram-positive coccal bacteremia and MDR Gram-positive coccal bacteremia predominantly occurred in patients with acute severe exacerbation of chronic hepatitis B and with fulminant/subfulminant hepatitis. Four independent risk factors for development of bacteremia caused by MDR Gram-positive coccus were： LT candidates with encephalopathy grades Ⅱ-Ⅳ （P=0.013, OR： 16.253, 95% CI：1.822-144.995）, pre-LT use of empirical antibiotics （P=0.018, OR： 1.029, 95% CI： 1.002-1.057）, post-LT urinary tract infections （P 〈0.001, OR： 20.340, 95% CI： 4.135-100.048） and abdominal infection （P=0.004, OR： 2.820, 95% CI：1.122-10.114）. The main infectious manifestations were coinfections due to gram-positive cocci and gram-negative ***

关键词： drug resistance, multiple Gram-positive coccus risk factors bacteremia liver transplantation

Morphology engineering of ZnO micro/nanostructures under mild conditions for optoelectronic application

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International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 498-503页

作者： Liang Chu Haoyu shen Hudie Wei Hongyu Chen Guoqiang Ma Wensheng yan Institute of Carbon Neutrality and New Energy&School of Electronics and Information Hangzhou Dianzi UniversityHangzhou 310018China School of Applied Physics and Materials Wuyi UniversityJiangmen 529020China

Zinc oxide(ZnO)serves as a crucial functional semiconductor with a wide direct bandgap of approximately 3.37 *** reaction is commonly used in the synthesis of ZnO micro/nanostructures,given its low cost,simplicity,and easy ***,ZnO morphology engineering has become desirable through the alteration of minor conditions in the reaction process,particularly at room *** this work,ZnO micro/nanostructures were synthesized in a solution by varying the amounts of the ammonia added at low temperatures(including room temperature).The formation of Zn^(2+)complexes by ammonia in the precursor regulated the reaction rate of the morphology engineering of ZnO,which resulted in various structures,such as nanoparticles,nanosheets,microflowers,and single ***,the obtained ZnO was used in the optoelectronic application of ultraviolet detectors.

关键词： morphology engineering low temperature ZnO nanosheets microflowers ultraviolet detector

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自适应陷波器噪声统计性能与相关性分析

电子学报 2018年第9期46卷 2108-2114页

作者：李明涂亚庆沈艳林沈廷鳌毛育文后勤工程学院后勤信息与军事物流工程系重庆401311

噪声是造成自适应陷波器(Adaptive Notch Filter,ANF)频率估计结果有偏的主要原因之一,在低信噪比条件下,噪声将极大的影响ANF频率估计方法的性能,特别在进行ANF统计性能分析的过程中,ANF传递函数的线性近似方法不再适用,此时将无法对AN... 详细信息

噪声是造成自适应陷波器(Adaptive Notch Filter,ANF)频率估计结果有偏的主要原因之一,在低信噪比条件下,噪声将极大的影响ANF频率估计方法的性能,特别在进行ANF统计性能分析的过程中,ANF传递函数的线性近似方法不再适用,此时将无法对ANF频率估计方法的精度等性能进行准确评估.为此,首先利用相关函数和功率谱分析噪声经不同变换后均值与方差的统计性能;其次,利用噪声分析的统计性能结果计算ANF频率估计方法的性能,为提升ANF频率估计方法的精度奠定理论分析基础;最后,对ANF频率估计方法的性能进行理论值与实际值的比对分析,结果表明噪声分析方法的有效性,并可近似预测ANF频率估计方法的稳态性能.

关键词：正弦信号噪声分析自适应陷波器频率估计

Serum sclerostin levels associated with lumbar spine bone mineral density and bone turnover markers in patients with postmenopausal osteoporosis

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Chinese Medical Journal 2013年第13期126卷 2480-2484页

作者： XU Xiao-juan shen lin yanG yan-ping LU Fu-rong ZHU Rui SHUAI Bo LI Cheng-gang WU Man-xiang Department of Integrated Traditional Chinese Medicine and Western Medicine Union Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan Hubei 430022 China

Background Sclerostin, expressed exclusively by osteocytes, is a negative regulator of bone formation. To gain insights into the action of sclerostin in postmenopausal osteoporosis, we evaluated serum sclerostin levels in postmenopausal women and investigated its possible associations with bone turnover markers in patients with postmenopausal osteoporosis. Methods We detected serum sclerostin, and measured lumbar spine bone mineral density in 650 Chinese postmenopausal women. We also assessed serum levels of 13-isomerized C-terminal crosslinking of type I collagen, intact N-terminal propeptide of type I collagen, N-mid fragment of osteocalcin, 25-hydroxyvitamin D, and estradiol. Results Serum sclerostin levels were lower in postmenopausal osteoporotic women compared with non-osteoporotic postmenopausal women （（38.79＋7.43） vs. （52.86＋6.69） pmol/L, P 〈0.001）. Serum sclerostin was positively correlated with lumbar spine bone mineral density （r=0.391, P 〈0.001） and weakly negatively correlated with [3-isomerized C-terminal crosslinking of type I collagen, intact N-terminal propeptide of type I collagen, N-mid fragment of osteocalcin （t= -0.225, P 〈0.001; r= -0.091, P=0.046; r= -0.108, P=0.018; respectively） in postmenopausal osteoporosis. There was no significant association of serum sclerostin with age, body mass index, 25-hydroxyvitamin D, and estradiol （r= -0.004, P=0.926; r=0.067, P=0.143; r=0.063, P=0.165; r= -0.045, P=0.324; respectively）.Conclusion Sclerostin may be involved in the pathogenesis of postmenopausal osteoporosis and may play a role in bone turnover.

关键词： sclerostin," postmenopausal osteoporosis bone mineral density

Recombinant human interleukin-11 for treatment of chemotherapy-induced thrombocytopenia in patients with gastrointestinal cancer

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The Chinese-German Journal of Clinical Oncology 2007年第5期6卷 450-452页

作者： Jie Li lin shen yan Li Xiaodong Zhang Jian Li Jifang Gong Wei Deng Department of Gastrointestinal Oncology Peking University School of Oncology Beijing Cancer Hospital ＆ Institute Bejing 100036 China

Objective： To evaluate the efficacy and safety of recombinant human interleukin-11 （rhIL-11） for the chemotherapy-induced thrombocytopenia in patients with gastrointestinal cancer. Methods： It was an opened and non-randomized controlled clinical study. When the platelet counts was under 75 × 10^9/L after chemotherapy, rhlL-11 was administered 25 μg/（kg·d） as a daily SC injection last for 7-14 days, or discontinued when platelet counts 〉 100 × 10^9/L. Results： Seventysix patients were enrolled into this study. The treatment group and the control group had thirty-eight cases, respectively. The mean recovery time to PLT ≥ 100 × 10^9/L was 8.1 days in treatment group, while in control group was 12.2 days （P 〈 0.01）. Moreover, the mean recovery time from PLT 〈_ 50 × 10^9/L to 〉 100 × 10^9/L was 8.9 days in treatment group, while in control group was 12.9 days （P 〈 0.05）. There was a statistical difference between the two groups. Major side effects included edema, fever, articular muscle soreness, but they were all mild and well tolerable. Conclusion： rhIL-11 can be safely and effectively used for the treatment of chemotherapy-induced thrombocytopenia in patients with gastrointestinal cancer.

关键词： recombinant human interleukin-11 (rhIL-11) gastrointestinal cancer thrembocytopenia chemotherapy

数值模拟技术在湿法脱硫除雾器优化设计上的应用

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热力发电 2007年第5期36卷 10-14,18页

作者：李文艳徐妍申林艳华北电力大学北京102206

利用数值模拟技术,通过改变烟气流速、叶片间距、布置级数、液滴直径等参数,对折板式除雾器内多相流流场进行数值模拟计算,分析了各参数对脱水率的影响,提出了提高脱水率的可行性方案。模拟结果与现场实际运行情况基本吻合,表明数值模... 详细信息

利用数值模拟技术,通过改变烟气流速、叶片间距、布置级数、液滴直径等参数,对折板式除雾器内多相流流场进行数值模拟计算,分析了各参数对脱水率的影响,提出了提高脱水率的可行性方案。模拟结果与现场实际运行情况基本吻合,表明数值模拟技术可用于湿法脱硫除雾器的优化设计。

关键词：火电机组湿法脱硫除雾器脱水率数值模拟