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蚌埠医学院学报 2018年第8期43卷 981-983,988页

作者：陈杰李慧慧 Mohsin razakashif 高淑娴周平郑庆委韦莉申林管俊昌蚌埠医学院感染与免疫重点实验室安徽蚌埠233030 浙江省建德市第一人民医院内科 311600 蚌埠医学院科研中心安徽蚌埠233030

目的:观察妊娠期孕鼠给予葡萄球菌肠毒素B(sEB)对其新生子代鼠脾脏淋巴细胞体外增殖的影响。方法:在sD大鼠妊娠第16天给予尾静脉注射15μg sEB,同时设立磷酸盐缓冲液(PBs)对照组。获取出生后3 d的新生鼠脾脏并分离淋巴细胞,将淋巴细胞与... 详细信息

目的:观察妊娠期孕鼠给予葡萄球菌肠毒素B(sEB)对其新生子代鼠脾脏淋巴细胞体外增殖的影响。方法:在sD大鼠妊娠第16天给予尾静脉注射15μg sEB,同时设立磷酸盐缓冲液(PBs)对照组。获取出生后3 d的新生鼠脾脏并分离淋巴细胞,将淋巴细胞与Con A或sEB共培养3 d,流式细胞仪检测新生鼠脾脏淋巴细胞亚群,液体闪烁仪测定细胞的增殖能力。结果:sEB组新生鼠脾脏中CD4^+T细胞比例在Con A或sEB刺激第1天分别较PBs组明显增加,但在第2~3天却明显降低(PsEB组新生鼠脾脏中CD4^+TCR Vβ8.2^+T细胞比例在Con A或sEB刺激的第1天及CD8^+TCR Vβ8.2^+T细胞比例分别较PBs组明显增加(PsEB组新生鼠脾脏淋巴细胞在Con A或sEB刺激后第1天增殖能力明显强于PBs组,但在第2~3天的增殖能力却又明显低于PBs组(PsEB可以影响新生鼠脾脏淋巴细胞的体外增殖。

关键词：葡萄球菌肠毒素B 妊娠脾脏淋巴细胞

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Fine‑tuning genomic and pedigree inbreeding rates in equine population with a deep and reliable stud book:the case of the Pura raza Española horse

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Journal of Animal science and Biotechnology 2023年第2期14卷 515-528页

作者： Davinia Isabel Perdomo‑Gonzalez Nora Laseca sebastian Demyda‑Peyras Mercedes Valera Isabel Cervantes Antonio Molina Departamento Agronomia Escuela Tecnica Superior de Ingenieria AgromomicaUniversidad de SevillaCtra Utrera Km 141013 SevillaSpain Departamento de Genetica Universidad de CordobaCordobaSpain Facultad de Ciencias Veterinarias Universidad Nacional de La PlataLa PlataArgentina Consejo Nacional de Investigaciones Cientificas y Tecnicas(CONICET) La PlataArgentina Departamento de Produccion Animal Facultad de VeterinariaUniversidad Complutense de MadridMadridSpain.

Background:Estimating inbreeding,which is omnipresent and inevitable in livestock populations,is a primary goal for management and animal breeding especially for those interested in mitigating the negative consequences of *** coefficients have been historically estimated by using pedigree information;however,over the last decade,genome-base inbreeding coefficients have come to the forefront in this *** Pura raza Espanola(PRE)horse is an autochthonous spanish horse breed which has been recognised since *** total PRE population(344,718 horses)was used to estimate Classical(F),Ballou’s ancestral,Kalinowski’s ancestral,Kalinowski’s new and the ancestral history coefficient *** addition,genotypic data from a selected population of 805 PRE individuals was used to determine the individual inbreeding coefficient using sNP-by-sNP-based techniques(methods of moments-FHOM-,the diagonal elements of the genomic-FG-,and hybrid matrixes-FH-)and ROH measures(FRZ).The analyse of both pedigree and genomic based inbreeding coefficients in a large and robust population such as the PRE horse,with proven parenteral information for the last 40 years and a high degree of completeness(over 90%for the last 70 years)will allow us to understand PRE genetic variability better and the correlations between the estimations will give the data greater ***:The mean values of the pedigree-based inbreeding coefficients ranged from 0.01(F for the last 3 generations-F3-)to 0.44(ancestral history coefficient)and the mean values of genomic-based inbreeding coefficients varied from 0.05(FRZ for three generations,FH and FHOM)to 0.11(FRZ for nine generations).significant correlations were also found between pedigree and genomic inbreeding values,which ranged between 0.58(F3 with FHOM)and 0.79(F with FRZ).In addition,the correlations between FRZ estimated for the last 20 generations and the pedigree-based inbreeding highlight the fact that fewer generations of

关键词： Genomic inbreeding Horses Pedigree inbreeding

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骆驼特异功能与饲养管理

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畜牧兽医科学（电子版） 2020年第10期 78-79页

作者：古丽努尔·马哈提拉扎提·艾尼瓦尔玛尔孜亚·亚森马桢阿布来提·苏来曼哈丽布布·热恒拜新疆畜牧科学院畜牧研究所乌鲁木齐830011 新疆昭苏县农业农村局伊犁835000

骆驼是荒漠半荒漠地带特有的畜种之一,骆驼养殖业也是当地的主体产业经济。骆驼以其耐粗饲,成本低,效益高,具有毛、乳、肉、旅游、皮等多种用途,为荒漠地区节粮型畜牧业发展、牧民增收、脱贫致富起到积极的推动作用。该文分析骆驼特异功... 详细信息

骆驼是荒漠半荒漠地带特有的畜种之一,骆驼养殖业也是当地的主体产业经济。骆驼以其耐粗饲,成本低,效益高,具有毛、乳、肉、旅游、皮等多种用途,为荒漠地区节粮型畜牧业发展、牧民增收、脱贫致富起到积极的推动作用。该文分析骆驼特异功能,并提出科学饲养和管理的措施,以便强化骆驼养殖效率。

关键词：骆驼养殖对策特异功能管理

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CEPC Technical Design Report

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Radiation Detection Technology and Methods 2024年第1期8卷 I0003-I0016,1-1091页

作者： Waleed Abdallah Tiago Carlos Adorno de Freitas Konstantin Afanaciev shakeel Ahmad Ijaz Ahmed Xiaocong Ai Abid Aleem Wolfgang Altmannshofer Fabio Alves Weiming An Rui An Daniele Paolo Anderle stefan Antusch Yasuo Arai Andrej Arbuzov Abdesslam Arhrib Mustafa Ashry sha Bai Yu Bai Yang Bai Vipul Bairathi Csaba Balazs Philip Bambade Yong Ban Tripamo Bandyopadhyay shou-shan Bao Desmond P.Barber Ayse Bat Varvara Batozskaya subash Chandra Behera Alexander Belyaev Michele Bertucci Xiao-Jun Bi Yuanjie Bi Tianjian Bian Fabrizio Bianchi Thomas Biekotter Michela Biglietti shalva Bilanishvili Deng Binglin Denis Bodrov Anton Bogomyagkov serge Bondarenko stewart Boogert Maarten Boonekamp Marcello Borri Angelo Bosotti Vincent Boudry Mohammed Boukidi Igor Boyko Ivanka Bozovic Giuseppe Bozzi Jean-Claude Brient Anastasiia Budzinskaya Masroor Bukhari Vladimir Bytev Giacomo Cacciapaglia Hua Cai Wenyong Cai Wujun Cai Yijian Cai Yizhou Cai Yuchen Cai Haiying Cai Huacheng Cai Lorenzo Calibbi Junsong Cang Guofu Cao Jianshe Cao Antoine Chance Xuejun Chang Yue Chang Zhe Chang Xinyuan Chang Wei Chao Auttakit Chatrabhuti Yimin Che Yuzhi Che Bin Chen Danping Chen Fuqing Chen Fusan Chen Gang Chen Guoming Chen Hua-Xing Chen Huirun Chen Jinhui Chen Ji-Yuan Chen Kai Chen Mali Chen Mingjun Chen Mingshui Chen Ning Chen shanhong Chen shanzhen Chen shao-Long Chen shaomin Chen shiqiang Chen Tianlu Chen Wei Chen Xiang Chen Xiaoyu Chen Xin Chen Xun Chen Xurong Chen Ye Chen Ying Chen Yukai Chen Zelin Chen Zilin Chen Gang Chen Boping Chen Chunhui Chen Hok Chuen Cheng Huajie Cheng shan Cheng Tongguang Cheng Yunlong Chi Pietro Chimenti Wen Han Chiu Guk Cho Ming-Chung Chu Xiaotong Chu Ziliang Chu Guglielmo Coloretti Andreas Crivellin Hanhua Cui Xiaohao Cui Zhaoyuan Cui Brunella D'Anzi Ling-Yun Dai Xinchen Dai Xuwen Dai Antonio De Maria Nicola De Filippis Christophe De La Taille Francesca De Mori Chiara De sio Elisa Del Core shuangxue Deng Wei-Tian Deng Zhi Deng Ziyan Deng Bhupal Dev Tang Dewen Biagio Di Micco Ran Ding siqin Dingl Yadong Ding Haiyi Dong Jianin AGH University of science and Technology Faculty of Physics and Applied Computer ScienceKrakow Anhui University HefeiAnhui Applied Physics Department Federal Urdu University of ArtsScience and TechnologyIslamabad Banaras Hindu University Institute of ScienceVaranasi Bandirma Onyedi Eylul University Bandirma Beihang University Beijing Beijing Computational science Research Center Beijing Beijing Conveyi LTD Beijing Beijing Glass Research Institute Co. LtdBeijing Beijing Institute of Technology Beijing Beijing Normal University Beijing Brown University ProvidenceRI Budker Institute of Nuclear Physics Novosibirsk Cadi Ayyad University Laboratory of Fundamental and Applied PhysicsPolydisciplinary FacultyMarrakech Cairo University Giza Center for Theory and Computation National Tsing Hua UniversityHsinchu Central China Normal University WuhanHubei Central south University ChangshaHunan Centro de Fisica Teorica de Particulas Universidade Tecnica de LisboaLisboa Chengdu Kaitengsifang Digital Radio&TV Equipment Co. LtdChengduSichuan China academy of engineering physics MianyangSichuan China building materials academy Beijing China Center of Advanced science and Technology Beijing China Institute of Atomic Energy Beijing China Jiliang University HangzhouZhejiang China Nuclear Instrument CO. LTDBeijing China University of Geosciences Beijing China University of Geosciences WuhanHubei China University of Mining and Technology XuzhouJiangsu China West Normal University NanchongSichuan Chongqing University Department of PhysicsChongqing Chulalongkorn University Bangkok City University of Hong Kong Department of PhysicsHong Kong Cockcroft Institute Daresbury Cornell University IthacaNY CPPM(AMU/IPhU&CNRs/INP) Marseille Dalian Minzu University DalianLiaoning Dalian University of Technology Department of PhysicsDalian Deutsches Elektronen-synchrotron DEsY Hamburg Dzhelepov Laboratory of Nuclear Problems of Joint Institute for Nuclear Research(DLNP JINR) Dubna East China University Of science And Technol

The Circular Electron Positron Collider(CEPC)is a large scientific project initiated and hosted by China,fostered through extensive collaboration with international *** complex comprises four accelerators:a 30 GeV Linac,a 1.1 GeV Damping Ring,a Booster capable of achieving energies up to 180 GeV,and a Collider operating at varying energy modes(Z,W,H,and tt).The Linac and Damping Ring are situated on the surface,while the subterranean Booster and Collider are housed in a 100 km circumference underground tunnel,strategically accommodating future expansion with provisions for a potential super Proton Proton Collider(sPPC).The CEPC primarily serves as a Higgs *** its baseline design with synchrotron radiation(sR)power of 30 MW per beam,it can achieve a luminosity of 5×10^(34)cm^(-2)s^(-1)per interaction point(IP),resulting in an integrated luminosity of 13 ab^(-1)for two IPs over a decade,producing 2.6 million Higgs *** the sR power to 50 MW per beam expands the CEPC's capability to generate 4.3 million Higgs bosons,facilitating precise measurements of Higgs coupling at sub-percent levels,exceeding the precision expected from the HL-LHC by an order of *** Technical Design Report(TDR)follows the Preliminary Conceptual Design Report(Pre-CDR,2015)and the Conceptual Design Report(CDR,2018),comprehensively detailing the machine's layout,performance metrics,physical design and analysis,technical systems design,R&D and prototyping efforts,and associated civil engineering ***,it includes a cost estimate and a preliminary construction timeline,establishing a framework for forthcoming engineering design phase and site selection *** is anticipated to begin around 2027-2028,pending government approval,with an estimated duration of 8 *** commencement of experiments and data collection could potentially be initiated in the mid-2030s.

关键词： initiated exceeding precise

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