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APPLICATION OF THE UNIFIED sTATIsTICAL MATERIAL DATABAsE FOR DEsIGN AND LIFE/RIsK AssEssMENT OF HIGH TEMPERATURE COMPONENTs

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Acta Metallurgica sinica(English Letters) 2004年第4期17卷 338-344页

作者： K.Fujiyama T.Fujiwara Y.Nakatani K.saito A.sakuma Y.Akikuni s.Hayashi s.matsumoto Power and Industrial systems R&D Center Industrial and Power Systems & Services Company Toshiba Corporation Tsurumi-Ku Yokohama 230-0045 JapanThermal and Hydro Power Division Industrial and Power Systems & Services Company Toshiba Corporation Minato-Ku Tokyo 105-8001 JapanPower and Industrial Systems R&D Center Industrial and Power Systems & Services Company Toshiba Corporation Tsurumi-Ku Yokohama 230-0045 JapanKeihin Product Operations Industrial and Power Systems & Services Company Toshiba CorporationTsurumi-Ku Yokohama 230-0045 JapanKeihin Product Operations Industrial and Power Systems & Services Company Toshiba CorporationTsurumi-Ku Yokohama 230-0045 JapanThermal and Hydro Power Division Industrial and Power Systems & Services Company Toshiba Corporation Minato-Ku Tokyo 105-8001 JapanThermal and Hydro Power Division Industrial and Power Systems & Services Company Toshiba Corporation Minato-Ku Tokyo 105-8001 JapanThermal and Hydro Power Division Industrial and Power Systems & Services Company Toshiba Corporation Minato-Ku Tokyo 105-8001 Japan

statistical manipulation of material data was conducted for probabilistic life assessment or risk-based design and maintenance for high temperature components of power plants. To obtain the statistical distribution of material properties, dominant parameters affecting material properties are introduced into normalization of statistical variables. Those parameters are hardness, chemical composition, characteristic micro structural features and so on. Creep and fatigue properties are expressed by normalized parameters and the unified statistical distributions are obtained. These probability distribution functions show good coincidence statistically with the field database of steam turbine components. It was concluded that the unified statistical baseline approach is useful for the risk management of components in power plants.

关键词： statistical analysis material property steam turbine life assessment risk

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Diels-Alder合成反应的化学计量学研究

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科学通报 1997年第20期42卷 2175-2178页

作者：肖敏胡芳梁本熹康继军 s.matsumoto Y.Muramatsu 李志良湖南大学化学化工系药物研究所长沙410082 日本早稻田大学化学与生化系日本国立科技大学知识信息系

化学计量学是一门将数学、计算机技术与化学交叉结合的新兴边缘学科,在化学化工及医药卫生等相关领域取得广泛应用.将化学计量学原理和方法及技术用于合成化学中便诞生了其新的分支即合成(化学)计量学.作者试验室对此进行了较深入而系... 详细信息

化学计量学是一门将数学、计算机技术与化学交叉结合的新兴边缘学科,在化学化工及医药卫生等相关领域取得广泛应用.将化学计量学原理和方法及技术用于合成化学中便诞生了其新的分支即合成(化学)计量学.作者试验室对此进行了较深入而系统的研究,取得了系列研究结果,并将予陆续报道.本文以著名的Diels—Alder反应为例,通过试验优化设计与多元潜因分析对其试验空间进行了系统考察和优化建模,获得满意结果.预测收率与实验收率吻合良好.1 试验(1)主要仪器和试剂.微量有机合成仪一套,无水三氯化铝(AR),用前经升华干燥处理;1,3—戊二烯(CP),甲苯(CP)作溶剂.其他试剂均为AR或CP以上纯度,使用去离子水.产物经IR,NMR,Ms,UV及元素分析鉴定为目标产物(2)试验方法.按文献[4～6]进行合成提纯产品并计算产率.

关键词：化学计量学合成计量学试验设计 D-A反应

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日本东北福岛县西南部观测的剪切波分裂

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世界地震译丛 1996年第2期27卷 68-76页

作者： T.Okada T.Matsuzawa s.matsumoto K.Nida A.Ito A.Hasegawa 杨导声浙江省地震局

我们研究了日本东北福岛县西南地区的剪切波偏振各向异性。研究的数据是从东北大学和字都宫大学的区域地震台网得到的。我们采用互相关方法,检测剪切波的分裂。对福岛县西南地区地下的浅源地震观测到的快剪切波振动方向(FsOD)呈NW-sE走... 详细信息

我们研究了日本东北福岛县西南地区的剪切波偏振各向异性。研究的数据是从东北大学和字都宫大学的区域地震台网得到的。我们采用互相关方法,检测剪切波的分裂。对福岛县西南地区地下的浅源地震观测到的快剪切波振动方向(FsOD)呈NW-sE走向。观测到的延迟时间小于0.1s,在地震活动水平高的地区,(延迟时间)值趋向增大。对中等深度地震,观测的快剪切波振动方向平行于消减板块倾斜的方向,大部分观测到的延迟时间小于1s。在这些观测的基础上,我们估计了各向异性的位置和成因。在福岛县西南地区地下的上地壳中,估计各向异性主要是由构造应力控制的破裂的优势取向产生的。

关键词：地震观测剪切波分裂地震活动性

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Denso公司新型柴油机用电磁阀式喷油器

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汽车与新动力 2014年第1期46卷 52-55页

作者： s.matsumoto K.Date T.Taguchi O.E.Herrmann 范明强

Denso公司新型第4代电磁阎式喷油器具有三路控制功能,因而提高了液力效率,并使燃油耗降低约1%。该喷油器的运动质量减轻75%,大大改善了液力性能。此外,其燃油泄漏量被减少到最低程度,明显降低了对冷却的要求,并且对燃油品质的波动不敏感。

关键词：柴油机电磁阀式喷油器共轨喷油器三路控制功能

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经导管主动脉瓣植入术(TAVI)前使用可变螺距扫描的CT成像及其对冠状动脉疾病的诊断效能

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国际医学放射学杂志 2017年第4期 482-483页

作者： s.matsumoto Y.Yamada M.Hashimoto T.Okamura M.Yamada F.Yashima 朱珍 Department of Diagnostic Radiology Keio University School of Medicine

摘要目的探讨TAVI前使用可变螺距(VHP)CT扫描的有效性及其对冠状动脉疾病的诊断性能。方法计划进行经导管主动脉瓣植入术(TAVI)检查的60例病人[(84.4±4.6)岁]进行可变螺距的CT扫描,对比剂的用量为扫描时间×体质量(kg)×0.06 mL。胸部...

摘要目的探讨TAVI前使用可变螺距(VHP)CT扫描的有效性及其对冠状动脉疾病的诊断性能。方法计划进行经导管主动脉瓣植入术(TAVI)检查的60例病人[(84.4±4.6)岁]进行可变螺距的CT扫描,对比剂的用量为扫描时间×体质量(kg)×0.06 mL。胸部检查使用回顾性心电门控扫描,随后立即进行非心电门控的腹部扫描。分析冠状动脉、主动脉、

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Detection and clearance in Alzheimer’s disease: leading with illusive chemical, structural and morphological features of the targets

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Neural Regeneration Research 2024年第3期19卷 497-498页

作者： Luís Gales i3s−Instituto de Investigação e Inovação em saúde Rua Alfredo AllenPortoPortugal(Gales L)IBMC−Instituto de Biologia Molecular e CelularUniversidade do PortoRua Alfredo AllenPortoPortugal ICBAs−Instituto de Ciências Biomédicas Abel salazar Rua de Jorge Viterbo FerreiraPortoPortugal

Highly specific interactions between biomolecules,such as antigen-antibody,protein-ligand,or nucleic acid base pair complementary are on the basis of the organization of complex *** same principles may be tentatively used in molecular medicine for diagnosis and therapeutics.A molecule can be designed to selectively bind a protease and thereby inhibit the production of a peptide that forms toxic aggregates in the brain or an antibody may be produced to bind specifically to that peptide for detection or clearance ***,interference in biological systems is not that *** a start there is the inhibition of the physiological role of the protease;moreover,several cleavage fragments may be produced,which may continue to diverge due to putative post-translational modification and self-assembly processes,hiding the toxic target in a“soup”of peptide species varying in size,structure and chemical composition.A perspective of the current status and challenges in targeting peptide species for diagnosis and treatment in the context of Alzheimer’s disease is given.

关键词： Alzheimer diagnosis thereby

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Astrophysical s-factor and reaction rate for 15N(p,γ)16O within the modified potential cluster model

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Chinese Physics C 2024年第4期48卷 130-145页

作者： s.B.Dubovichenko A.s.Tkachenko R.Ya.Kezerashvili N.A.Burkova B.M.Yeleusheva Fesenkov Astrophysical Institute 050020 AlmatyKazakhstan New York City College of Technology City University of New YorkBrooklyn11201 New YorkUSA Graduate school and University Center City University of New York10016 New YorkUSA al-Farabi Kazakh National University 050040 AlmatyKazakhstan

We study radiative p^(15)N capture on the ground state of ^(16)O at stellar energies within the framework of a modified potential cluster model(MPCM)with forbidden states,including low-lying *** investigation of the ^(15)N(p,γ0)^(16)O reaction includes the consideration of ^(3)s_(1) resonances due to E1 transitions and the contribution of the ^(3)P_(1) scattering wave in the p+^(15)N channel due to the ^(3)P_(1)→^(3)P_(0)M1 *** calculated the astrophysical low-energy s-factor,and the extrapolated s(0)turned out to be within 34.7−40.4 keV·*** important role of the asymptotic constant(AC)for the ^(15)N(p,γ0)16O process with interfering ^(3)s_(1)(312)and ^(3)s_(1)(962)resonances is elucidated.A comparison of our calculation for the s-factor with existing experimental and theoretical data is addressed,and a reasonable agreement is *** reaction rate is calculated and compared with the existing *** has negligible dependence on the variation of AC but shows a strong impact of the interference of ^(3)s_(1)(312)and ^(3)s_(1)(962)resonances in reference to the CNO Gamow windows,especially at low *** estimate the contribution of cascade transitions to the reaction rate based on the exclusive experimental data from ***.C.85,065810(2012).The reaction rate enhancement due to the cascade transitions is observed from T_(9)>0.3 and reaches the maximum factor~1.3 at T_(9)=*** present the Gamow energy window and a comparison of rates for radiative proton capture reactions ^(12)N(p,γ)^(13)O,^(13)N(p,γ)^(14)O,^(14)N(p,γ)^(15)O,and ^(15)N(p,γ)^(16)O obtained in the framework of the MPCM and provide the temperature windows,prevalence,and significance of each process.

关键词： low and astrophysical energies p^(15)N system thermonuclear reaction rate potential cluster model CNO-cycle

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哮喘:比较动态氧增强MRI和定量薄层CT临床治疗评价

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国际医学放射学杂志 2015年第1期 80-80页

作者： Y.Ohno M.Nishio H.Koyama s.seki T.Yoshikawa s.matsumoto Advanced Biomedical Imaging Research Center Kobe University Graduate School of MedicineKobe

目的比较用动态氧增强MR成像和定量评估CT评价哮喘病人临床分期和由于治疗导致的肺功能改变。材料与方法神户大学医院的机构审查委员会批准了这项研究,

关键词：哮喘病人神户大学机构审查委员会 MRI 临床分期 CT

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Carotenoid productivity in human intestinal bacteria Eubacterium limosum and Leuconostoc mesenteroides with functional analysis of their carotenoid biosynthesis genes

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Engineering Microbiology 2024年第2期4卷 1-11页

作者： Wataru matsumoto Miho Takemura Haruka Nanaura Yuta Ami Takashi Maoka Kazutoshi shindo shin Kurihara Norihiko Misawa Research Institute for Bioresources and Biotechnology Ishikawa Prefectural University1-308SuematsuNonoich-shi 921-8836Japan Department of science and Technology on Food safety Kinki University930 NishimitaniKinokawaWakayama 649-6493Japan Research Institute for Production Development Shimogamo-morimotochoSakyo-kuKyoto 606-0805Japan Department of Food and Nutrition Japan Women’s UniversityMejirodaiBunkyo-kuTokyo 112-8681Japan

The human intestinal microbiota that comprise over 1,000 species thrive in dark and anaerobic *** are recognized for the production of diverse low-molecular-weight metabolites crucial to human health and ***,low-molecular-weight pigments known for their antioxidative activity,are delivered to humans through oral ***,it remains unclear whether human intestinal bacteria biosynthesize carotenoids as part of the in-situ *** this study,we investigated carotenoid synthesis genes in vari-ous human gut and probiotic *** a result,novel candidates,the crtM and crtN genes,were identified in the carbon monoxide-utilizing gut anaerobe Eubacterium limosum and the lactic acid bacterium Leuconostoc mesenteroides *** gene candidates were isolated,introduced into Escherichia coli,which synthesized a carotenoid substrate,and cultured *** analysis of the resulting carotenoids re-vealed that the crtM and crtN gene candidates of *** and *** mediate the production of 4,4′-diaponeurosporene through 15-cis-4,4′-*** of the crtE-homologous genes in these bacteria indicated their non-functionality for C40-carotenoid *** and ***,along with the known carotenogenic lactic acid bacterium Lactiplantibacillus plantarum,were observed to produce no carotenoids under strictly anaerobic *** two lactic acid bacteria synthesized detectable levels of 4,4′-diaponeurosporene under semi-aerobic *** findings highlight that the obligate anaerobe ***-sum retains aerobically functional C30-carotenoid biosynthesis genes,potentially with no immediate self-utility,suggesting an evolutionary direction in carotenoid biosynthesis.(229 words)

关键词： C_(30)carotenoid biosynthesis Obligate anaerobe Human gut bacterium Eubacterium limosum Leuconostoc mesenteroides Lactiplantibacillus plantarum

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The autophagy protein Atg9 functions in glia and contributes to parkinsonian symptoms in a Drosophila model of Parkinson’s disease

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Neural Regeneration Research 2024年第5期19卷 1150-1155页

作者： shuanglong Yi Linfang Wang Margaret s.Ho shiping Zhang school of Life science and Technology ShanghaiTech UniversityShanghaiChina College of Life sciences University of Chinese Academy of SciencesBeijingChina

Parkinson’s disease is a progressive neurodegenerative disease characterized by motor deficits,dopaminergic neuron loss,and brain accumulation ofα-synuclein aggregates called Lewy *** in protein degradation pathways,such as autophagy,has been demonstrated in neurons as a critical mechanism for eliminating protein aggregates in Parkinson’s ***,it is less well understood how protein aggregates are eliminated in glia,the other cell type in the *** the present study,we show that autophagy-related gene 9(Atg9),the only transmembrane protein in the autophagy machinery,is highly expressed in Drosophila glia from adult *** from immunostaining and live cell imaging analysis reveal that a portion of Atg9 localizes to the trans-Golgi network,autophagosomes,and lysosomes in ***9 is persistently in contact with these *** glial atg9 reduces the number of omegasomes and autophagosomes,and impairs autophagic substrate *** suggests that glial Atg9 participates in the early steps of autophagy,and hence the control of autophagic ***,loss of glial atg9 induces parkinsonian symptoms in Drosophila including progressive loss of dopaminergic neurons,locomotion deficits,and glial *** findings identify a functional role of Atg9 in glial autophagy and establish a potential link between glial autophagy and Parkinson’s *** results may provide new insights on the underlying mechanism of Parkinson’s disease.

关键词： Atg9 autophagy glia Parkinson’s disease

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