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Establishment of an animal model of extra-vertebral foramen cervical nerve entrapment by local electrical stimulation and selection of suitable stimulation parameters

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Neural Regeneration Research 2011年第29期6卷 2284-2289页

作者： Jinwu Wang juliet Hou Qi Li Jian Tang Biyu Rui shangchun Guo Haitao Jiang Cunyi Fan You Wang Zhenan Zhu Kerong Dai Guang H Yue Department of Orthopedic surgery the Ninth People＇s Hospital Shanghai Jiao Tong University School of Medicine Shanghai 200011 China Department of Physical Medicine ＆ Rehabilitation the Cleveland Clinic Cleveland Ohio 44195 USA Department of Orthopaedic surgery the Sixth Municipal People＇s Hospital Shanghai Jiao Tong University Shanghai 200233 China Biomedical Engineering the Cleveland Clinic Cleveland Ohio 44195 USA

A rat model of extra-vertebral foramen cervical nerve entrapment was established according to the following parameters： stimulation intensity 20 V; frequency 50 Hz; pulse width 200 μs; duration 333 ms/s for a total of 8 hours. After the electrical stimulation, rats exhibited mild muscle fiber atrophy, mild inflammatory exudates, connective tissue local fibrosis and chondrocyte metaplasia. Mean muscle fiber cross-sectional area was reduced. The nerve myelin sheath continuity was partially demyelinated. The microstructure of nerve cells was disrupted and these symptoms worsened with prolongation of the stimulation. The shoulder, neck and upper extremity muscles on the tested side demonstrated positive sharp waves and fibrillations. The severity increased with continuation of the stimulation. High amplitude and polyphasic motor unit potentials gradually appeared. similar findings were seen in the contralateral side, but at a less severe level.

关键词： chronic neck-shoulder pain electrical stimulation extra-vertebral foramen cervical nerve entrapment syndrome animal model

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Assessment of UAV Based Vegetation Indices for Nitrogen Concentration Estimation in spring Wheat

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Advances in Remote sensing 2018年第2期7卷 71-90页

作者： Olga s. Walsh sanaz shafian juliet M. Marshall Chad Jackson Jordan R. McClintick-Chess steven M. Blanscet Kristin swoboda Craig Thompson Kelli M. Belmont Willow L. Walsh Department of Plant sciences Southwest Research and Extension Center University of Idaho Moscow ID USA Department of Entomology Plant Pathology and Nematology Idaho Falls Research and Extension Center University of Idaho Idaho Falls ID USA BAsF-Chemical Co. Caldwell ID USA Take Flight UAs LLC Boise ID USA seminis Payette ID USA Vallivue High school Caldwell ID USA

Unmanned Aerial Vehicles (UAVs) have become increasingly popular in recent years for agricultural research. High spatial and temporal resolution images obtained with UAVs are ideal for many applications in agriculture. The objective of this study was to evaluate the performance of vegetation indices (VIs) derived from UAV images for quantification of plant nitrogen (N) concentration of spring wheat, a major cereal crop worldwide. This study was conducted at three locations in Idaho, United states. A quadcopter UAV equipped with a red edge multispectral sensor was used to collect images during the 2016 growing season. Flight missions were successfully carried out at Feekes 5 and Feekes 10 growth stages of spring wheat. Plant samples were collected on the same days as UAV image data acquisition and were transferred to lab for N concentration analysis. Different VIs including Normalized Difference Vegetative Index (NDVI), Red Edge Normalized Difference Vegetation Index (NDVIred edge), Enhanced Vegetation Index 2 (EVI2), Red Edge simple Ratio (sRred edge), Green Chlorophyll Index (CIgreen), Red Edge Chlorophyll Index (CIred edge), Medium Resolution Imaging spectrometer (MERIs) Terrestrial Chlorophyll Index (MTCI) and Red Edge Triangular Vegetation Index (core only) (RTVIcore) were calculated for each flight event. At Feekes 5 growth stage, red edge and green based VIs showed higher correlation with plant N concentration compare to the red based VIs. At Feekes 10 growth stage, all calculated VIs showed high correlation with plant N concentration. Empirical relationships between VIs and plant N concentration were cross validated using test data sets for each growth stage. At Feekes 5, the plant N concentration estimated based on NDVIred edge showed one to one correlation with measured N concentration. At Feekes 10, the estimated and measured N concentration were highly correlated for all empirical models, but the model based on CIgreen was the only model that had a one to

关键词： Unmanned Aerial Vehicles and systems (UAV) Vegetation Indices (VIs) Plant Nitrogen Concentration

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(-)-Epigallocatechin-3-Gallate Enhances Hepatitis C Virus Doublestranded RNA Intermediates-Triggered Innate Immune Responses in Hepatocytes

(-)-Epigallocatechin-3-Gallate Enhances Hepatitis C Virus Do...

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中华医学会第七次全国艾滋病、丙型肝炎学术会议

作者： Wang Yizhong Jieliang Li Wang Xu Zhou Yu Pena juliet C Li Kui Zhang Ting Ho Wenzhe Department of Infectious Diseases Shanghai Children’s HospitalShanghai Jiao Tong University Department of Pathology and Laboratory Medicine Temple University School of Medicine Deparment of Microbiology Immunologyand BiochemistryUniversity of Tennessee Health Science Center

(-)-Epigallocatechin-3-gallate(EGCG),a major polyphenol component of green tea,has recently been identified as an inhibitor of hepatitis C virus(HCV)***,we examined whether EGCG can enhance hepatocyte-mediated intracellular innate immunity against *** dsRNAs(Core,E1-P7,Ns-3'NTR and Ns5A)induced interferon-l1(IFN-l1)expression in human *** HCV

关键词： HCV Epigallocatechin-3-Gallate Enhances Hepatitis C Virus Doublestranded RNA Intermediates-Triggered Innate Immune Responses in Hepatocytes RNA

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文莱技术教育面临的挑战与对策

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职业教育研究 2018年第12期 83-87页

作者：侯翠钻吴绍容穆罕默德.法齐拉.哈吉.阿卜杜拉赵学瑶文莱教育部战略管理局宁德职业技术学院福建福安355000 文莱技术教育学院广州市白云工商技师学院广东广州510450

技术教育转型是文莱实施系列发展战略的重要内容。在转型过程中,文莱技术教育学院(IBTE)始终扮演着关键角色并发挥着重要作用,同时还在课程改革、增加学徒选择机会、提供深造机会、改进培训环境、新的服务计划、教育品牌重塑、关键绩效... 详细信息

技术教育转型是文莱实施系列发展战略的重要内容。在转型过程中,文莱技术教育学院(IBTE)始终扮演着关键角色并发挥着重要作用,同时还在课程改革、增加学徒选择机会、提供深造机会、改进培训环境、新的服务计划、教育品牌重塑、关键绩效指标方面进行了探索实践。

关键词：文莱技术教育:转型挑战关键绩效指标

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AME证据系列001--转化医学协会:脓毒症诊断和早期识别的临床实践指南

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临床与病理杂志 2016年第10期36卷 1467-1476页

作者： Zhongheng Zhang Nathan J.smischney Haibo Zhang sven Van Poucke Panagiotis Tsirigotis Jordi Rello Patrick M.Honore Win sen Kuan juliet June Ray Jiancang Zhou You shang Yuetian Yu Christian Jung Chiara Robba Fabio silvio Taccone Pietro Caironi David Grimaldi stefan Hofer George Dimopoulos Marc Leone sang-Bum Hong Mabrouk Bahloul Laurent Argaud Won Young Kim Herbert D.spapen Jose Rodolfo Rocco 张建成(译) 尚游(译) 钟鸣(校) Department of Emergency Medicine Sir Run Run Shaw HospitalZhejiang University School of MedicineHangzhou 310016 Department of Critical Care Medicine Jinhua Hospital of Zhejiang UniversityJinhua Zhejiang 321000 Department of Anesthesiology Mayo ClinicRochesterMNUSA Keenan Research Center for Biomedical science of st.Michael's Hospital Departments of Anesthesia and PhysiologyInterdepartmental Division of Critical Care MedicineUniversity of TorontoTorontoONCanada Departments of Anesthesiology Critical CareEmergency Medicine and Pain TherapyZiekenhuis Oost-Limburgy GenkBelgium 2nd Department of Internal Medicine Attikcon University HospitalMedical SchoolNational and Kapodistrian University of AthensAthensGreece CIBEREs Vall d'Hebron Institut of ResearchUniversitat Autonoma de BarcelonaSpain Universitair Ziekenhuis Brussely Vrije Universiteit Brussel Brussels BrusselsBelgium Emergency Medicine Department National University HospitalNational University Health SystemSingapore and the Department of SurgeryYong Loo Lin School of MedicineNational University of SingaporeSingapore DeWitt Daughtry Family Department of surgery Jackson Memorial HospitalUniversity of Miami Leonard M.Miller School of MedicineMiamiFLUSA Department of Critical Care Medicine Sir Run Run Shaw HospitalZhejiang University School of MedicineHangzhou 310016 Department of Critical Care Medicine Union HospitalTongji Medical CollegueHuazhong University of Science and TechnologyWuhan 430022 Department of Critical Care Medicine Renji HospitalShanghai Jiao Tong University School of MedicineShanghai 200001 University Hospital Dusseldorf Heinrich-Heine-University DusseldorfMedical FacultyDivision of CardiologyPulmonology and Vascular MedicineDusseldorfGermany Neurosciences Critical Care Unit Addenbrooke's HospitalCambridgeUK Department of Intensive Care Hopital ErasmeUniversite Libre de Bruxelles(ULB)BrusselsBelgium Dipartimento di Fisiopatologia Medico-Chirurgica e dei Trapianti Fondazione IRCCS Ca'Granda-Ospedale

脓毒症是一种由感染引起的异质性疾病,感染触发了一系列复杂的局部或者全身的免疫炎症反应,引起多器官功能衰竭,发病率和病死率显著升高。由于至今仍然没有诊断脓毒症的金标准,所以脓毒症的临床诊断仍是一个难题。因此,脓毒症的临床诊... 详细信息

脓毒症是一种由感染引起的异质性疾病,感染触发了一系列复杂的局部或者全身的免疫炎症反应,引起多器官功能衰竭,发病率和病死率显著升高。由于至今仍然没有诊断脓毒症的金标准,所以脓毒症的临床诊断仍是一个难题。因此,脓毒症的临床诊断需要不断改变来满足临床和研究的要求。然而,尽管有许多新型的生物标记和筛选工具去预测脓毒症发生的风险,但是这些措施的诊断价值和有效性不足以让人满意,并且没有充分的证据去建议临床使用这些新技术。因此,脓毒症的临床诊断标准需要定期更新去适应不断产生的新证据。这篇综述旨在呈现当前脓毒症的诊断和早期识别方面的最新研究证据。临床运用不同的诊断方法的推荐意见依赖于推荐、评价、发展和评估分级体系(Grades of Recommendation Assessment,Development and Evaluation,GRADE),因为大部分的研究是观察性研究,并没有对这些方法进行可靠评估,采用的是两步推理方法。未来需要更多研究来确认或者反驳某一特殊的指标检测,同时应该直接采用相关病人的结果数据。

关键词：脓毒症早期识别诊断

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