(-)-Epigallocatechin-3-Gallate Enhances Hepatitis C Virus DoubleStranded RNA Intermediates-Triggered Innate Immune Responses in Hepatocytes
作者单位：Department of Infectious DiseasesShanghai Children’s HospitalShanghai Jiao Tong University Department of Pathology and Laboratory MedicineTemple University School of Medicine Deparment of MicrobiologyImmunologyand BiochemistryUniversity of Tennessee Health Science Center
会议名称：《中华医学会第七次全国艾滋病、丙型肝炎学术会议》
会议日期：2015年
学科分类：1007[医学-药学(可授医学、理学学位)] 100705[医学-微生物与生化药学] 1001[医学-基础医学(可授医学、理学学位)] 100103[医学-病原生物学] 10[医学]
关 键 词：HCV Epigallocatechin-3-Gallate Enhances Hepatitis C Virus DoubleStranded RNA Intermediates-Triggered Innate Immune Responses in Hepatocytes RNA
摘 要：(-)-Epigallocatechin-3-gallate(EGCG),a major polyphenol component of green tea,has recently been identified as an inhibitor of hepatitis C virus(HCV)***,we examined whether EGCG can enhance hepatocyte-mediated intracellular innate immunity against *** dsRNAs(Core,E1-P7,NS-3 NTR and NS5A)induced interferon-l1(IFN-l1)expression in human *** HCV