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AUTORADIOGRAPHIC sTUDy OF THE ATTRITION OF MIGRATING sCHIsTOsOMULA IN THE sKIN OF MICE *** CHALLENGED WITH NORMAL *** CERCARIAE AFTER IMMUNIZATION WITH HIGHLy IRRADIATED CERCARIAE

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Chinese Medical sciences Journal 1990年第1期8卷 30-36页

作者： s.y.li hsu H.F.hsu J.W.Osborne W.R.Clarke C.K.Hawk y.Ohnishi College of Medicine University of IowaIowaUSA

The migratory pattern and attrition of75se-labelled *** challenge cercariae in CF1mice immunized 0,1,3, or 5 times with 12kR-or 48kR-irradiated cercariae were investigatedby compressed organ *** were percutaneously in... 详细信息

The migratory pattern and attrition ofsup>75sup>se-labelled *** challenge cercariae in CF1mice immunized 0,1,3, or 5 times with 12kR-or 48kR-irradiated cercariae were investigatedby compressed organ *** were percutaneously inoculated with 500-1000 cer-cariae for each immunization and with a known count of approximately 90 cercariae at adifferent site for *** skin,lungs,liver,other organs,and catrcass were processedfor *** and mesenteric perfusions for worm collection were alsosampled from day 19 through *** naive tnice,25% of challenge cercariae died in *** attrition of challenge cercariae in mice immunized with 12kR-irradiated cercariaewas 43% with 1 immunization,54% with 3,and 58% with 5,whereas in mice immunized with48kR-irradiated cercariae,skin,attrition was48% with 1,63% with 3,and 76% with 5 *** all immunized mice,a high percentage of migrating sehistosomula died in the skinwithin 24 hours of a challenge *** autoradiography,it was found that thesilver foci created by single labelled worms were difficult to differentiate from those of *** study documents the induction of acquired resistance against a challenge infectionin the skin by vaccination with highly irradiated cercariae,with the degree of attemtation ofimmunizing cercariae and the number of immunizations being closely related to the *** in the ***,we discuss the contradictory views concerning the site of attritiotn ofchallenge cercariae.

关键词： autoradiography attrition—challenge cercariae immunization—highly X-irradiated cercariae schistosoma mansoni

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A robust vector tracking loop structure based on potential bias analysis

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Chinese Journal of Aeronautics 2024年第4期37卷 405-420页

作者： Qiongqiong JIA yiran LUO Bing XU li-Ta hsu Renbiao WU Tianjin Key Lab for Advanced signal Processing Civil Aviation University of ChinaTianjin 300300China Interdisciplinary Division of Aeronautical and Aviation Engineering The Hong Kong Polytechnic University999077Hong KongChina Department of Geomatics Engineering University of CalgaryCalgary T2N1N4Canada

This paper proposes a robust vector tracking loop structure based on potential bias analysis. The influence of four kinds of biases on the existing two implementations of Vector Tracking Loops(VTLs) is illustrated by theoretical analysis and numerical simulations, and the following findings are obtained. Firstly, the initial user state bias leads to steady navigation solution bias in the relative VTL, while new measurements can eliminate it in the absolute VTL. secondly, the initial code phase bias is transferred to the following navigation solutions in the relative VTL, while new measurements can eliminate it in the absolute VTL. Thirdly, the user state bias induced by erroneous navigation solution of VTLs can be eliminated by both of the two VTLs. Fourthly,the multipath/NLOs likely affects the two VTLs, and the induced tracking bias in the duration of the multipath/NLOs would decrease the performance of VTLs. Based on the above analysis,a robust VTL structure is proposed, where the absolute VTL is selected for its robustness to the two kinds of initialization biases;meanwhile, the instant bias detection and correction method is used to improve the performance of VTLs in the duration of the multipath/NLOs. Numerical simulations and experimental results verify the effectiveness of the proposed robust VTL structure.

关键词： Global Navigation satellite system(GNss) Vector Tracking Loop(VTL) Multipath Non-line-of-sight(NLOs) Tracking bias propagation Least Absolute shrinkage and selection Operator(LAssO)

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Recent Advances in Electrochemical-Based silicon Production Technologies with Reduced Carbon Emission

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Research 2024年第1期2023卷 209-236页

作者： Feng Tian Zhongya Pang shen Hu Xueqiang Zhang Fei Wang Wei Nie Xuewen Xia Guangshi li Hsien-yi hsu Qian Xu Xingli Zou li Ji Xionggang Lu state Key Laboratory of Advanced special steel&shanghai Key Laboratory of Advanced Ferrometallurgy&school of Materials science and Engineering Shanghai University99#Shangda RoadShanghai 200444China Center for Hydrogen Metallurgy Technology Shanghai UniversityShanghai 200444China state Key Laboratory of AsIC and system School of MicroelectronicsFudan University220#Handan RoadShanghai 200433China school of Energy and Environment Department of Materials Science and EngineeringCity University of Hong KongKowloon TongHong KongChina

sustainable and low-carbon-emission silicon production is currently one of the main focuses for the metallurgical and materials science ***,considered a promising strategy,has been explored to produce silicon due to prominent advantages:(a)high electricity utilization efficiency;(b)low-cost silica as a raw material;and(c)tunable morphologies and structures,including films,nanowires,and *** review begins with a summary of early research on the extraction of silicon by *** has been placed on the electro-deoxidation and dissolution–electrodeposition of silica in chloride molten salts since the 21st century,including the basic reaction mechanisms,the fabrication of photoactive si films for solar cells,the design and production of nanosi and various silicon components for energy conversion,as well as storage ***,the feasibility of silicon electrodeposition in room-temperature ionic liquids and its unique opportunities are *** this basis,the challenges and future research directions for silicon electrochemical production strategies are proposed and discussed,which are essential to achieve large-scale sustainable production of silicon by electrochemistry.

关键词： directions electrodeposition electricity

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Mirrorless MEMs imaging:a nonlinear vibrational approach utilizing aerosol-jetted PZT-actuated fiber MEMs scanner for microscale illumination

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Microsystems & Nanoengineering 2024年第1期10卷 175-192页

作者： Wei-Chih Wang Ming-yao li Kuan-Chang Peng yi-Feng hsu Benjamin Estroff Pao-yun yen David schipf Wen-Jong Wu Department of Power Mechanical Engineering National Tsing Hua UniversityNo.101Section 2Kuang-Fu RoadHsinchuTaiwan 30013China Institute of NanoEngineering and Microsystems National Tsing Hua UniversityNo.101Section 2Kuang-Fu RoadHsinchuTaiwan 30013China Department of Mechanical Engineering University of WashingtonSeattleWA 98195USA Department of Electrical Engineering University of WashingtonSeattleWA 98195USA Department of Engineering science and Ocean Engineering National Taiwan UniversityTaiwanChina

This study introduces a novel image capture and lighting techniques using a cutting-edge hybrid MEMs scanner system designed for compact microscopic *** scanner comprises a tapered optical fiber waveguide and innovative aerosol-jet printed PZT(lead zirconate titanate)bimorph push-pull actuators on a stainless-steel substrate,effectively addressing issues that are commonly associated with PZT on silicon substrates such as fracture and layer *** leveraging nonlinear vibration,the scanner achieves a spiral scan pattern from a single signal input,in addition to the expected two-dimensional scanning and target illumination from two phase-shifted *** capability is further enhanced by a novel process to taper the optical fiber,which reduces illumination scattering and tunes the fiber to the resonant frequencies of the *** precisely tapered tip enables large fields of view while maintaining independent 2-axis scanning through one-degree-of-freedom *** validation showcases the successful generation of a spiral scan pattern with a 60μm diameter scan area and a 10 Hz frame rate,effectively reconstructing scanned images of 5μm lines,cross patterns(15μm in length with a 5μm gap),and structures of a Psychodidae wing.

关键词： steel fiber scanner

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Ascophyllum nodosum and Fucus vesiculosus ameliorate restenosis via improving inflammation and regulating the PTEN/PI3K/AKT signaling pathway

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Food science and Human Wellness 2024年第3期13卷 1711-1728页

作者： Crystal Ngofi Zumbi Chun-hsu Pan Hui-yu Huang Chieh-Hsi Wu Program in Clinical Drug Development from Herbal Medicine College of PharmacyTaipei Medical UniversityTaipei 11031China Program in Drug Discovery and Development Industry College of PharmacyTaipei Medical UniversityTaipei 11031China school of Pharmacy Taipei Medical UniversityTaipei 11031China Graduate Institute of Metabolism and Obesity sciences Taipei Medical UniversityTaipei 11031China

Restenosis is a common complication following coronary *** traditional use of seaweeds for health benefits has increasingly been explored,however few studies exist reporting its protective effects on the development of restenosis and gut *** aim of this study was to investigate the potential of seaweed extracts(sE) of Ascophyllum nodosum and Fucus vesiculosus in inhibiting intimal hyperplasia in a rat model of restenosis and its underlying mechanisms in macrophages and vascular smooth muscle cells(vsMCs).16s rRNA sequencing was done to investigate the regulatory effect of sE on the gut microbiome of injured *** indicated by the results,sE significantly inhibited the progression of intimal hyperplasia in vivo,attenuated inflammation in macrophages and could inhibit the proliferation,dedifferentiation and migration of *** was observed through immunoblotting assays that treatment with sE significantly upregulated PTEN expression in macrophages and inhibited the upregulation of PI3K and AKT expression in ***,according to the 16s rRNA gene sequencing analysis,supplementation with sE modulated gut microbiota composition in injured *** conclusion,sE could ameliorate intimal hyperplasia by inhibiting inflammation and vsMCs proliferation through the regulation of the PTEN/PI3K/AKT pathway and modulating the gut microbiome.

关键词： Ascophyllum nodosum Fucus vesiculosus PTEN/PI3K/AKT Restenosis Macrophage Vascular smooth muscle cells Gut microbiota

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Understanding pediatric surgical needs in North Korea: a modeling analysis

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World Journal of Pediatric surgery 2024年第1期7卷 47-53页

作者： Phillip J hsu sangchul yoon Kee B Park University of Michigan Ann ArborMichiganUSA Department of Global Health and social Medicine Harvard Medical SchoolBostonMassachusettsUSA Department of Medical Humanitiesand social sciences yonsei University SeoulSouth Korea

Background sixty-five percent of children worldwide lack access to surgical care,the majority of whom live in low-income and middle-income countries(LMiCs).Developing surgical infrastructure requires information on surgical need;however,this information is often limited in *** Korea(Democratic People's Republic of Korea,DPRK)has a low amount of publicly available ***,we analyzed available modeled data to understand the causes of pediatric deaths due to conditions treatable with surgery in *** We used World Bank data and models from the Institute for Health Metrics and Evaluation to identify causes of pediatric deaths affecting pediatric patients(ageyears).We compared mortality of disease between DPRK and countries with similar economic *** Between 1990 and 2019,the number of overall pediatric deaths has *** 2019,32.2%of allpediatric deaths in DPRK were caused by surgical *** leading categories of surgical conditions were injuries(53.9%),congenital conditions(34.2%),tumors(8.8%),and abdominal conditions(3.2%).DPRK has a lower relative rate of pediatric deaths compared with other LMICs with similar gross domestic product per ***,it has a higher relative rate of pediatric deaths due to conditions requiring treatment with *** injuries contribute significantly to the high rate of pediatric deaths in *** Although DPRK may be allocating overall resources toward pediatric healthcare more efficiently than economic peers,DPRK may benefit from improvement in pediatric surgical *** availability of data and close international collaboration could be potential solutions to bridge this gap.

关键词： pediatric surgical injuries

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High-performance Bi_(2)s_(3)/ZnO photoanode enabled by interfacial engineering with oxyanion for efficient photoelectrochemical water oxidation

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Nano Research 2024年第7期17卷 5996-6005页

作者： ying-Chu Chen Hsiang-yu Jui yichen Feng yun-Hsiang Lu yu-Kuei hsu Department of Chemical Engineering&Biotechnology "National Taipei University of Technology"No.1Sec.3Zhong-Xiao E.Rd.Da'an Dist.Taipei City 10608TaiwanChina Department of Opto-Electronic Engineering "National Dong Hwa University"No.1Sec.2Da Hsueh RoadShoufengHualien 97401TaiwanChina China-UK Low Carbon College Shanghai Jiao Tong UniversityNo.3Yinlian RoadLingangShanghai 201306China

In the present contribution,we demonstrate that the sluggish kinetics of oxygen evolution reaction(OER)over the bismuth sulfide(Bi_(2)s_(3))photoanode,which severely restricts its photoelectrochemical activity,is markedly accelerated by employing a sulfatecontaining ***-principle calculation points to the spontaneous adsorption of sulfate(sO_(4)^(2−))on Bi_(2)s_(3)and its capacity of stabilizing the OER intermediates through hydrogen bonding,which is further reinforced by increasing the local density of states near the Fermi level of Bi_(2)s_(3).Meanwhile,the electron transfer is also promoted to synergistically render the ratedetermining step(from O*to OOH*)of OER over Bi_(2)s_(3)kinetically *** but not least,benefitting from such enhanced OER activity and efficient charge separation resulted from depositing Bi_(2)s_(3)on the zinc oxide nanorods(ZnO NRs),forming a core–shell heterojunction,its photocurrent density achieves 8.61 mA·cm^(−2)at 1.23 VRHE,far surpassing those reported for additional Bi_(2)s_(3)-based and several state-of-the-art photoanodes in the literature and further exceeding their theoretical *** great promise of the Bi_(2)s_(3)/ZnO NRs is in view of such outperformance,the superior Faradaic yield of oxygen of more than~80%and the outstanding half-cell applied bias photon-to-current efficiency of~1%well corroborated.

关键词： photoelectrochemical water oxidation oxyanion adsorption electronic structure regulation oxygen evolution reaction(OER)intermediates stabilization Bi_(2)s_(3)

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Hypermethylation of the ALOX12 and CBs promoters in osteoporosis:Potential biomarkers for early diagnosis

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Genes & Diseases 2024年第1期11卷 30-33页

作者： shang Guo yue Wu Weekai Chia Peichun hsu Hongwei Wang yunliang Wang Biao Zhong Department of Orthopedic surgery Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of MedicineShanghai 200023China Institute of Translational Medicine Shanghai General HospitalShanghai Jiao Tong University School of Medicine(SJTU-SM)Shanghai 200025China The University of Chicago Department of MedicineChicagoIL 60637USA Department of Neurology The Second Affiliated Hospital of Zhengzhou UniversityZhengzhouHenan 450014China

As a bone-confined chronic degenerative disorder,the progression of osteoporosis is characterized by abnormal crosstalk between osteoblasts and osteoclasts,leading to an imbalance of bone remodeling in adults.1 several studies reported that arachidonic acid ester 12 lipoxygenase(ALOX12)acts as a regulator in bone genesis by participating in the activation of the peroxisome proliferatoractivated receptor(PPARG)pathway through its reaction product.

关键词： osteoporosis diagnosis remodeling

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Low-temperature selective synthesis of metastableα-MoC with electrochemical properties:Electrochemical co-reduction of CO_(2)and MoO_(3)in molten salts

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Chinese Chemical Letters 2024年第1期35卷 310-315页

作者： Longtao Zhu yinan Zhao Wenhao yang Hsien-yi hsu Ping Peng Fang-Fang li school of Materials science and Engineering Huazhong University of Science and TechnologyWuhan 430074China school of Energy and Environment&Department of Materials science and Engineering City University of Hong KongHong Kong 999077China

Metastable molybdenum carbide(α-MoC),as a catalyst and an excellent support for metal catalysts,has been widely used in thermo/electro-catalytic ***,the selective synthesis ofα-MoC remains a great ***,a simple one-pot synthetic strategy for the selective preparation of metastableα-MoC is proposed by electrochemical co-reduction of CO_(2)and MoO_(3)in a low-temperature eutectic molten *** synthesizedα-MoC shows a reed flower-like *** controlling the electrolysis time and monitoring the phase and morphology of the obtained products,the growth process ofα-MoC is revealed,where the carbon matrix is deposited first followed by the growth ofα-MoC from the carbon ***,by analyzing the composition of the electrolytic products,the formation mechanism forα-MoC is *** addition,through this one-pot synthetic strategy,s-dopedα-MoC is successfully *** functional theory(DFT)calculations reveal that s doping enhanced the HER performance ofα-MoC by facilitating water absorption and dissociation and weakening the bond energy of Mo-H to accelerate H *** present work not only highlights the valuable utilization of CO_(2) but also offers a new perspective on the design and controllable synthesis of metal carbides and their derivatives.

关键词： α-MoC CO_(2)electroreduction Molten salt sulfur doping Hydrogen evolution reaction

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Concurrent occurrence of adenocarcinoma and urothelial carcinoma of the prostate gland:A case report

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World Journal of Clinical Cases 2024年第26期12卷 5952-5959页

作者： Jhe yuan hsu yi sheng lin li Hua Huang Tang yi Tsao Chao yu hsu yen Chuan Ou Min Che Tung Division of Urology Department of SurgeryTungs'Taichung MetroHarbor HospitalTaichung 435403Taiwan Department of Pathology Tungs'Taichung MetroHarbor HospitalTaichung 435403Taiwan

BACKGROUND Adenocarcinoma is the most common subtype of prostate *** urothelial carcinoma(UC)typically originates from the prostatic *** concurrent occurrence of adenocarcinoma and UC of the prostate gland is *** sUMMARy We present the case of an 82-year-old male patient with simultaneous adenocarcinoma and UC of the prostate *** patient underwent a transrectal ultrasound-guided biopsy,and the pathology test revealed ***,transurethral laser prostatectomy was performed,and the pathology test indicated adenocarcinoma of the prostate with a Gleason score of 3+4 and highgrade ***,the patient was treated with androgen deprivation therapy,systemic chemotherapy,and *** resonance imaging performed during follow-up revealed a prostate tumor classified as cT2cN1M0,stage ***,the patient underwent robotic-assisted radical prostatectomy and bilateral pelvic lymph node *** final pathology test of the prostate gland revealed acinar-type adenocarcinoma,Gleason pattern 4+3,pT2N0M0,and high-grade *** patient regularly presented to the clinic for postoperative follow-up *** did not experience any urinary *** According to our literature review,this is the first reported case of coexisting adenocarcinoma and UC of the prostate gland.

关键词： Adenocarcinoma Urothelial carcinoma Prostate Coexist Case report

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