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Coastal wetlands in Lianyungang,Jiangsu Province,China:probably the most important site globally for the Asian Dowitcher(Limnodromus semipalmatus)

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Avian Research 2021年第3期12卷 364-374页

作者： Ziyou Yang Jing Li Yongxiang Han Chris J.Hassell kar-sin katherine Leung David s.Melville Yat-tung Yu Lin Zhang Chi-Yeung Choi spoon-Billed sandpiper(shanghai)Environmental Protection Technology Co. Ltd.Shanghai 201100China Lianyungang Xugou Primary school Lian-yungang 222042China Global Flyway Network PO Box 3089BroomeWA 6725Australia Hong kong Waterbirds Ringing Group Mai Po Nature ReserveHong KongChina 1261 Dovedale Road RD 2 WakefieldNelson 7096New Zealand Hong kong Bird Watching society 7CV Ga Building532 Castle Peak RoadLai Chi KokKowloonHong KongChina school of Environmental science and Engineering Southern University of Science and TechnologyShenzhen 518055China

Background:despite an increasing number of surveys and a growing interest in birdwatching,the population and distribution of Asian Dowitcher(Limnodromus semipalmatus),a species endemic to the East Asian-Australasian and Central Asian Flyways,remains poorly understood,and published information about the species is largely *** boreal spring 2019,over 22,432 Asian Dowitchers were recorded in a coastal wetland at Lianyungang,Jiangsu Prov-ince,China,constituting 97.5%of its estimated global ***:In 2019 and 2020,we conducted field surveys at Lianyungang to determine the numbers of Asian Dow-itchers using the area during both southward and northward *** also assessed the distribution and abun-dance of Asian Dowitchers elsewhere along the China coast by searching literature and consulting expert ***:The coastal wetlands of Lianyungang are the most important stopover site for Asian Dowitchers during both northward and southward migrations;they supported over 90%of the estimated global population during north-ward migration in two consecutive years(May 2019 and 2020).This area also supported at least 15.83%and 28.42%(or 30.74%and 53.51%using modelled estimates)of the global population during southward migration in 2019 and 2020 *** wetlands in the west and north of Bohai Bay also have been important stopover sites for the species since the *** comprehensive,long-term monitoring data are lacking,available evidence sug-gests that the population of the species may have ***:The high concentration of Asian Dowitchers at Lianyungang during migration means the species is highly susceptible to human disturbances and natural stochastic *** coastal wetlands of Lianyungang should be protected and potentially qualify for inclusion in China’s forthcoming nomination for World Heritage listing of Migratory Bird sanctuaries along the Coast of Yellow sea-Bohai Gulf of China(Phase II)in ***

关键词： Lianyungang Limnodromus semipalmatus shorebird stopover ecology Yellow sea World Heritage

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Nat Genet:单细胞分析解开结直肠癌细胞的神秘面纱

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现代生物医学进展 2017年第15期17卷 I0003-I0003页

作者： Huipeng Li, Elise T Courtois, debarka sengupta, Yuliana Tan shyam Prabhakar Elise T Courtois, Yuliana Tan Paul Robson debarka sengupta kok Hao Chen, Jolene Jie Lin Goh Paul Jongjoon Choi say Li kong, Axel M Hillmer Iain Beehuat Tan Clarinda Chua Iain Beehuat Tan Lim kiat Hon Wah siew Tan Mark Wong Lawrence J k Wee Iain Beehuat Tan Paul Robson Paul Robson Paul Robson Computational and systems Biology Genome Institute of Singapore Singapore developmental Cellomics Laboratory Genome Institute of Singapore Singapore department of Computer science and Engineering and Center for Computational Biology Indraprastha Institute of Information Technology Delhi India synthetic Biology Genome Institute of Singapore Singapore Cancer Therapeutics and stratified Oncology Genome Institute of Singapore Singapore department of Medical Oncology National Cancer Centre Singapore Singapore department of Pathology Singapore General Hospital Singapore department of Colorectal surgery Singapore General Hospital Singapore Data Analytics department Institute for Infocomm Research Singapore Program in Cancer and stem Cell Biology Duke-NUS Medical School Singapore The Jackson Laboratory for Genomic Medicine Farmington Connecticut USA department of Genetics and Genome sciences Institute for Systems Genomics University of Connecticut Farmington Connecticut USA department of Biological sciences National University of Singapore Singapore.

结合单细胞基因组学和计算机技术，一个研究团队（包括来自杰克逊实验室（JAx）单细胞生物学主任Paul Robson博士在内）鉴定出了11种结直肠癌肿瘤的癌细胞组成及邻近的非癌细胞。这对于更好的肿瘤靶向诊断和治疗很重要。”使用单细胞测... 详细信息

结合单细胞基因组学和计算机技术，一个研究团队（包括来自杰克逊实验室（JAx）单细胞生物学主任Paul Robson博士在内）鉴定出了11种结直肠癌肿瘤的癌细胞组成及邻近的非癌细胞。这对于更好的肿瘤靶向诊断和治疗很重要。”使用单细胞测序。”JAX科学家、这篇发表在Nature Genetics上的文章共同第一作者Elise Courtois说道。”我们可以根据肿瘤中的细胞组成将结直肠癌进一步分类。因为每种亚型的肿瘤病人生存率存在差别，我们的方法将为肿瘤医生提供更多的关于肿瘤预后和治疗的信息。”

关键词：单细胞分析结直肠癌癌细胞 Nat 细胞组成肿瘤病计算机技术细胞生物学

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常染色体显性遗传性感觉神经病变伴慢性咳嗽和胃食管反流:2个染色体3p22-p24相关家族的临床特征

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世界核心医学期刊文摘（神经病学分册） 2006年第6期2卷 54-54页

作者： spring P.J. kok C. Nicholson G.A. 高宗恩 department of Neurology Concord Hospital Hospital Road Concord NSW 2139 Australia Dr.

Autosomal dominant hereditary sensory neuropathy (HsN I) is a clinically and genetically heterogeneous group of disorders, and in some families it is due to mutations in the serine palmitoyltransferase (sPTLC1) gene. We have characterized two families with HsN I associated with cough and gastro-oesophageal reflux (GOR). From a large Australian family, 27 individuals and from a smaller family, 11 individuals provided clinical information and blood for genetic analysis. Affected individuals had an adult onset of paroxysmal cough, GOR and distal sensory loss. Cough could be triggered by noxious odours or by pressure in the external auditory canal (Arnold’s ear-cough reflex). Other features included throat clearing, hoarse voice, cough syncope and sensorineural hearing loss. Neurophysiological and pathological studies demonstrated a sensory axonal neuropathy. Gastric emptying studies were normal, and autonomic function and sweat tests were either normal or showed distal hypohidrosis. Cough was likely to be due to a combination of denervation hypersensitivity of the upper airways and oesophagus, and prominent GOR. Most affected individuals were shown on 24 h ambulatory oesophageal pH monitoring to have multiple episodes of GOR, closely temporally associated with coughing. Hoarse voice was probably attributable to acid-induced laryngeal damage, and there was no evidence of vocal cord palsy. No other cause for cough was found on most respiratory or otorhinological studies. Linkage to chromosome 3p22-p24 has been found in both families, with no evidence of linkage to loci for known HsN I, autosomal dominant hereditary motor and sensory neuropathy, hereditary GOR or triple A syndrome. These families represent a genetically novel variant of HsN I, with a distinctive cough owing to involvement of the upper aerodigestive tract.

关键词：常染色体显性遗传性感觉神经病变胃食管反流慢性咳嗽临床特征个染色体家族感觉神经性耳聋外耳道压力

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香港绿谷公司诉加拿大绿谷公司等股权纠纷案

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中国法律（中英文版） 2006年第4期 43-44,112-114页

作者： the Editorial Board of the Gazette of the supreme People’s Court 最高人民法院公报编辑部

1991年7月18日，黄耀林、刘建国在香港注册成立绿谷投资有限公司（以下简称香港绿谷公司）。1994年6月1日，郝晓荧、吕嘉东在加拿大注册成立绿谷（国际）投资与管理有限公司（以下简称加拿大绿谷公司）。1996年，香港绿谷公司的股束变... 详细信息

1991年7月18日，黄耀林、刘建国在香港注册成立绿谷投资有限公司（以下简称香港绿谷公司）。1994年6月1日，郝晓荧、吕嘉东在加拿大注册成立绿谷（国际）投资与管理有限公司（以下简称加拿大绿谷公司）。1996年，香港绿谷公司的股束变更为黄耀林、黄光明、刘欣然、郝晓荧、吕嘉东五人，每人占20％股份，董事由黄耀林、黄光明、刘欣然、郝晓荧、吕嘉东、赵晶晶六人担任。

关键词：加拿大绿谷公司香港绿谷公司纠纷案股权刘建国简称

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determinants for asthma control, quality of life and use of complementary and alternative medicine in asthmatic pediatric patients in four cities

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World Journal of Pediatrics 2018年第5期14卷 482-491页

作者： kam Lun Hon Yan Min Bao kate C.Chan kin Wai Chau Rong-shan Chen kun Tat Gary Cheok Wa keung Chiu Li deng Chun-Hui He kin Mui Ieong Jeng sum C.kung Ping Lam shu Yan David Lam Qun Ui Lee so Lun Lee Ting Fan Leung Theresa N.H.Leung Lei shi ka ka siu Wei-Ping Tan Maggie Haitian Wang Tak Wai Wong Bao-Jing Wu Ada Y.F.Yip Yue-Jie Zheng Daniel k.Ng department of Pediatrics The Chinese University of Hong Kong 6/F Prince of Wales HospitalRoom 84042ShatinN.THong Kong SARChina department ofR espiratory Diseases Shenzhen Children’s HospitalShenzhen 518026China Hong kong society of P ediatric Respirology and Aller gy Hong K ong S ARChina Pediatric Respiratory andsleep Disorders Center Room 1315DArgyle Centre Phase 1688 Nathan RoadMongkokKowloonHong K ong S ARChina department of R espiration Guangzhou Women and Children’s Medical CenterGuangzhou 510623China department of P ediatrics Kiang Wu HospitalMacaoChina department of P ediatrics and A dolescent Medicine United Christian Hospital130Hip Wo StreetKwun TongHong K ong S ARChina department of P ediatrics Central Hospital Conde S.JanuarioMacaoChina department of P ediatrics and A dolescent Medicine Caritas Medical Center111Wing Hong StreetSham Shui PoHong K ong S ARChina department of P ediatrics and A dolescent Medicine Tuen Mun Hospital23 Tsing Chung Koon RoadTuen MunNewT erritoriesHongK ongS ARChina department of P ediatrics and A dolescent Medicine Princess Margaret Hospital2-10 Princess Margaret Hospital RoadLai Chi KokKowloonHong K ong S ARChina department of P ediatrics and A dolescent Medicine Queen Mary Hospital102Pokfulam RoadHong K ong S ARChina department of P ediatrics and A dolescent Medicine The University of Hong KongHong K ong S ARChina department of P ediatrics and A dolescent Medicine Pamela Youde Nethersole Eastern Hospital3Lok Man RoadChaiwanHong K ong S ARChina department of P ediatrics The University of Hong Kong-Shenzhen Hospital1Haiyuan 1st RoadFutianShenzhenChina department of P ediatrics and A dolescent Medicine Kwong Wah Hospital25 Waterloo RoadKLN Hong K ong S ARChina department of P ediatrics Sun Yat-sen Memorial HospitalSun Yat-sen UniversityGuangzhou 510120China JC school of Public Health and Primary Care Faculty of MedicineThe Chinese University of Hong KongHong K ong S ARChina department of P ediatrics and A dolescen

Background Asthma is a significant chronic health problem worldwide. Management aims at disease control by reducing functional impairment and exacerbations and improving quality of life (QoL). We report a multi-center study to survey asthma control and QoL in four cities in the Pearl River delta. Methods The conjoint survey involved ten Hong kong pediatric hospitals/units, two shenzhen hospitals, two Macao hos-pitals, and two Guangzhou hospitals on asthma control (using Asthma Control Test) and QoL (Pediatric Allergic Disease Quality of Life Questionnaire, PADQLQ). Acceptability of a treatment is graded as very good/good/fair/poor. Results Good asthma control was only reported in 80% subjects in Hong kong, but higher in sister cities (85–94%, Ps, 'incense burning', and 'smoker in family' were prevalent among the four cities. Logistic regres-sion showed better control of asthma was associated with better PADQLQ (B=?0.029, P smoker in family' (B=?0.83, P = 0.015) and various PADQLQ domains. Conversely, worse PADQLQ was associated with allergic rhinitis severity (B=4.77, P sthma (B=7.56, P sed frequency of traditional Chinese medicine use (B=1.7, P sed fre-quency of bronchodilator usage (B=1.05, P smoker in family' (B=4.05, P se burning at home (B=3.9, P sions There are some clinical and cultural differences among the four southern Chinese cities within the Guangdong province. This study identifies potentially modifiable environmental and treatment factors associated with poor asthma control and QoL for health-care interventions. Having a smoker in the family is independently associated with poor asthma control and QoL.

关键词： Asthma Complementary and alternative medicine Control Inhaled bronchodilator Inhaled corticosteroid Pediatric Allergic Disease Quality of Life Questionnaire smoking Traditional Chinese medicine

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