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Tuning thermal expansion by a continuing atomic rearrangement mechanism in a multifunctional titanium alloy

journal of Materials science & Technology 2021年第21期80卷 234-243页

作者： D.L.Gong H.L.Wang E.G.Obbard s.j.li R.Yang Y.L.Hao shi-changxu Innovation Center for Advanced Materials Institute of Metal ResearchChinese Academy of SciencesShenyang110016China school of Materials science and Engineering University of Science and Technology of ChinaShenyang110016China school of Mechanical Engineering Dongguan University of TechnologyDongguan523808China Department of Electrical Engineering and Telecommunications University of New South WalesSydneyNSW2052Australia

As to multifunctional titanium alloys with high strength and low elastic modulus, thermal training is crucial to tune their thermal expansion from positive to negative, resulting in a novel linear expansion which is stable in a wide temperature range. Aided by the high-order Hooke's law of elastic solids,a reversible atomic rearrangement mechanism was proposed to explain the novel findings which are unexpected from typical shape memory alloys. To confirm this continuous mechanism, a Ti-Nb based alloy, which possesses a nanoscale spongy microstructure consisting of the interpenetrated Nb-rich and Nb-lean domains produced by spinodal decomposition, was used to trace the crystal structure change by in-situ high energy synchrotron X-ray diffraction analyses. By increasing exposure time, the overlapped diffraction peaks can be separated accurately. The calculated results demonstrate that, in the nanoscale Nb-lean domains, the crystal structure parameters vary linearly with changing temperature along the atomic pathway of the bcc-hcp transition. This linear relationship in a wide temperature range is unusual for first-order martensitic shape memory alloys but is common for Invar alloys with high-order spin transitions. Furthermore, the alloy exhibits smooth DsC curves free of transformation-induced heat peaks observed in shape memory alloys, which is consistent with the proposed mechanism that the reversible transition is of high-order.

关键词： Coefficient of thermal expansion Multifunctional titanium alloys spongy microstructure Atomic rearrangement Elastic anisotropy

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Atomistic Investigation of shock-Induced Amorphization within Micro-shear Bands in Hexagonal Close-Packed Titanium

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Acta Metallurgica sinica(English Letters) 2024年第9期37卷 1590-1600页

作者： Z.C.Meng K.G.Wang T.Ali D.li C.G.Bai D.s.Xu s.j.li A.H.Feng G.j.Cao j.H.Yao Q.B.Fan H.Wang R.Yang Institute of Metal Research Chinese Academy of SciencesShenyang 110016China school of Materials science and Engineering University of Science and Technology of ChinaShenyang 110016China Interdisciplinary Centre for Additive Manufacturing(ICAM) School of Materials and ChemistryUniversity of Shanghai for Science and TechnologyShanghai 200093China school of Materials science and Engineering Tongji UniversityShanghai 201804China Key Laboratory for light-Weight Materials Nanjing Tech UniversityNanjing 210009China National Key Laboratory of science and Technology on Materials Under shock and Impact School of Materials Science and EngineeringBeijing Institute of TechnologyBeijing 100081China Beijing Institute of Technology Chongqing Innovation Center Chongqing 401135China

The mechanical response of a single crystal titanium sample against(0001)α surface impact was investigated using molecular dynamics ***,non-uniform plastic deformation was observed in the *** high strain rates,amorphization occurred near the edge of the contact region where severe shear strain induced a large number of stacking faults(sFs)and *** contrast,the central part of the contact region underwent less deformation with significantly fewer ***,instead of amorphization by consuming sFs and dislocations,there was a gradual increase in the density of dislocations and sFs during the process of *** local amorphous regions eventually grew into shear bands.

关键词： shock compression Amorphization shear band Titanium Molecular dynamics

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NMR Evidence for Universal Pseudogap Behavior in Quasi-Two-Dimensional Fese-Based superconductors

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Chinese Physics Letters 2022年第12期39卷 71-76页

作者： B.L.Kang M.Z.shi D.Zhao s.j.li j.li L.X.Zheng D.W.song L.P.Nie T.Wu X.H.Chen Hefei National Research Center for Physical sciences at the Microscale University of Science and Technology of ChinaHefei 230026China Key Laboratory of strongly coupled Quantum Matter Physics Department of PhysicsUniversity of Science and Technology of ChinaHefei 230026China CAs Center for Excellence in superconducting Electronics(CENsE) Shanghai 200050China 4Collaborative Innovation Center of Advanced Microstructures Nanjing UniversityNanjing 210093China Hefei National Laboratory University of Science and Technology of ChinaHefei 230088China

Recently,by intercalating organic ions into bulk Fese superconductors,two kinds of layered Fese-based superconductors[(TBA)xFese and(CTA)xFese]with superconducting transition temperatures(Tc)above 40 K have been *** to the large interlayer distance(~15A),these new layered superconductors have a large resistivity anisotropy analogous to bismuth-based cuprate ***,remarkable pseudogap behavior well above Tcis revealed by nuclear magnetic resonance(NMR)measurements on77se nuclei,suggesting a preformed pairing scenario similar to that of ***,we report another new kind of organic-ion-intercalated Fese superconductor,(PY)xFese,with a reduced interlayer distance(~10A)compared to(TBA)xFese and(CTA)*** performing77se NMR and transport measurements,we observe a similar pseudogap behavior well above Tcof~40 K and a large resistivity anisotropy of~10~4 in(PY)*** these facts strongly support a universal pseudogap behavior in these layered Fese-based superconductors with quasi-two-dimensional electronic structures.

关键词： NMR superconductors layered

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Microstructures and Hardness Properties for β-Phase Ti-24Nb-4Zr-7.9sn Alloy Fabricated by Electron Beam Melting

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journal of Materials science & Technology 2013年第11期29卷 1011-1017页

作者： j.Hernandez s.j.li E.Martinez L.E.Murr X.M.Pan K.N.Amato X.Y.Cheng F.Yang C.A.Terrazas s.M.Gaytan Y.L.Hao R.Yang F.Medina R.B.Wicker Department of Metallurgical and Materials Engineering The University of Texas at El Paso shenyang National Laboratory for Materials science Institute of Metal ResearchChinese Academy of Sciences school of Materials science and Engineering Dalian University of Technology W.M.Keck Center for 3D Innovation The University of Texas at E1 Paso

Atomized, pre-alloyed Ti-24Nb-4Zr-7.9sn （wt%） powder was used to fabricate solid, prototype components by electron beam melting （EBM）. Vickers microindentation hardness values were observed to average 2 GPa for the precursor powder and 2.5 GPa for the solid, EBM-fabricated products. The powder and solid product microstructures were examined by optical and electron microscopy. X-ray diffraction analyses showed that they had bcc β-phase microstructure. However, it was found by transmission electron microscopy that the EBM-fabricated product had plate morphology with space -100-200 nm. Although the corresponding selected area diffraction patterns can be indexed by β-phase plus α＂-martensite with orthorhombic crystal structure, the dark-field analyses failed to observe the α＂-martensite. such phenomenon was also found in deformed gum metals and explained by stress-induced diffusion scattering due to phonon softening.

关键词： Biomedical titanium alloy β-Martensite Electron beam melting Hardness Optical and electron microscopy

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Efficacy and safety of Duloxetine on Osteoarthritis Knee Pain:A Meta-analysis of Randomized Controlled Trials

Efficacy and Safety of Duloxetine on Osteoarthritis Knee Pai...

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2016年广东省药师周大会

作者： Z.Y.Wang s.Y.shi s.j.li F.Chen j H Zheng H.Z.lin W Zhou j.M.lin Guangdong Province Key Laboratory for Biotechnology Drug Candidates School of Biosciences and BiopharmaceuticsGuangdong Pharmaceutical University Department of Pharmacy Zhujiang HospitalSouthern Medical University Department of Pharmacy Yue Bei people's HospitalShantou University Pharmaceutical Research & Development Zhujiang HospitalSouthern Medical University

Objectives:The aim of this meta-analysis was to evaluate the efficacy and safety of duloxetine for management of osteoarthritis knee(OAK) ***:A systematic literature search of articles for management of OAK using duloxetine were performed in Pub Med,EBsCO,EMBAsE,science Direct,MEDliNE,Clinical ***,Google scholar,and Cochrane Central Register of Controlled Trials from the available date of inception until the latest issue(October 2013).Potentially relevant randomized controlled trials(RCTs) regarding to comparison of efficacy and safety of duloxetine with placebo for managing OAK pain were ***,studies with specific data regarding to pain reductions and response rate,PGI-I,functional improvement,Western Ontario and Mc Master Osteoarthritis Index(WOMAC),adverse events,TEAEs,mortality were included and analyzed,and those with confounding conditions were *** were assessed for quality using the jadad 5-point score for ***,a meta-analysis of all RCTs eligible for inclusion criteria was performed using Review Manager 5.1 meta-analysis ***:Three RCTs that enrolled 1,011 patients were included in our *** were statistically significant differences between patients taking duloxetine and those taking placebo with regard to the reductions in pain intensity [992 patients,mean difference(MD) =-0.88,95% confidence interval(CI)-1.11 to-0.65,p

关键词： duloxetine osteoarthritis knee pain meta-analysis randomized controlled trials

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Hugan Qingzhi exerts anti-inflammatory effects in a rat model of non-alcoholic fatty liver disease

Hugan Qingzhi exerts anti-inflammatory effects in a rat mode...

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2016年广东省药师周大会

Ethnopharmacological relevance:The Hugan Qingzhi tablet(HQT) is a traditional Chinese medicine used for treating NAFLD(non-alcoholic fatty liver disease).The present study evaluated the anti-inflammatory effects of HQT in rats with *** and methods:NAFLD was induced by a high-fat diet over a 12-week period,during which HQT was administered daily to the experimental *** markers,histopathological data,and oxidative stress/antioxidant biomarkers were ***-inflammatory cytokines interleukin-1β(IL-1β),tumor necrosis factor α(TNF-α) and interleukin-6(IL-6) were detected by enzyme-linked *** of silent information regulator 1(sIRT1) and acetylated-Nuclear-factor kappa B-p65(Ac-NF-κB-p65) were performed by western ***:At high and moderate doses,HQT was highly effective in decreasing serum alanine aminotransferase(pspartate aminotransferase(psterol(ps(ps(ps was associated with reduced histological steatosis and inflammation,and significantly increased superoxide dismutase,glutathione peroxidase(GPX),and total antioxidant serum activities(psting with a significant decrease in hepatic malondialdehyde levels(pses of HQT reduced hepatic levels of the pro-inflammatory cytokines TNF-α(psIRT1 expression and depressed Ac-NF-κB-p65 expression at protein ***:In our NAFLD rat model,HQT exerted substantial anti-inflammatory and antioxidant activities,possibly involving the regulation of sIRT1 and Ac-NF-κB-p65 expression.

关键词： Non-alcoholic fatty liver disease Inflammation Hugan Qingzhi tablet silent information regulator 1 Nuclear factor-κB

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Constraints on holographic QCD phase transitions from PTA observations

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science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 71-78页

作者： song He li li sai Wang shao-jiang Wang Center for Theoretical Physics and College of Physics Jilin University school of Physical science and Technology Ningbo University Max Planck Institute for Gravitational Physics (Albert Einstein Institute) CAs Key Laboratory of Theoretical Physics Institute of Theoretical Physics Chinese Academy of Sciences school of Fundamental Physics and Mathematical sciences Hangzhou Institute for Advanced StudyUniversity of Chinese Academy of Sciences (UCAS) school of Physical sciences University of Chinese Academy of Sciences (UCAS) Theoretical Physics Division Institute of High Energy Physics Chinese Academy of Sciences

The underlying physics of QCD phase transition in the early Universe remains largely unknown due to its strong-coupling nature during the quark-gluon plasma/hadron gas transition, yet a holographic model has been proposed to quantitatively fit the lattice QCD data while with its duration of the first-order phase transition(FoPT) left undetermined. At specific baryon chemical potential, the first-order QCD phase transition agrees with the observational constraint of baryon asymmetry. It, therefore, provides a scenario for phase transition gravitational waves(GWs) within the standard model of particle physics. If these background GWs could contribute dominantly to the recently claimed common-spectrum red noise from pulsar timing array(PTA) observations, the duration of this FoPT can be well constrained, and the associated primordial black holes are still allowed by current observations.

关键词： pulsar timing array QCD phase transition gravitational waves primordial black holes

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Cell polarization in ischemic stroke: molecular mechanisms and advances

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Neural Regeneration Research 2025年第3期20卷 632-645页

作者： Yuanwei li Xiaoxiao Xu Xuan Wu jiarui li shiling Chen Danyang Chen Gaigai li Zhouping Tang Department of Neurology Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei ProvinceChina

Ischemic stroke is a cerebrovascular disease associated with high mortality and disability rates. since the inflammation and immune response play a central role in driving ischemic damage, it becomes essential to modulate excessive inflammatory reactions to promote cell survival and facilitate tissue repair around the injury site. Various cell types are involved in the inflammatory response, including microglia, astrocytes, and neutrophils, each exhibiting distinct phenotypic profiles upon stimulation. They display either proinflammatory or anti-inflammatory states, a phenomenon known as ‘cell polarization.’ There are two cell polarization therapy strategies. The first involves inducing cells into a neuroprotective phenotype in vitro, then reintroducing them autologously. The second approach utilizes small molecular substances to directly affect cells in vivo. In this review, we elucidate the polarization dynamics of the three reactive cell populations(microglia, astrocytes, and neutrophils) in the context of ischemic stroke, and provide a comprehensive summary of the molecular mechanisms involved in their phenotypic switching. By unraveling the complexity of cell polarization, we hope to offer insights for future research on neuroinflammation and novel therapeutic strategies for ischemic stroke.

关键词： astrocyte polarization immune regulation inflammation ischemic injury microglia polarization neutrophil polarization signaling pathways stroke

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Women in visual neural regeneration research

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Neural Regeneration Research 2025年第2期20卷 489-490页

作者： Tonia s.Rex David j.Calkins Vanderbilt Eye Institute Vanderbilt University Medical CenterNashvilleTNUSA

The year 2024 marks the 60^(th)anniversary of Title IX and 25 years since the New York Times revealed bias against female faculty members at the Massachusetts Institute of *** take an opportunity here to examine the state of gender bias in a relatively new yet already prominent field,neural regeneration in the visual system,for which there is a well-defined context useful for this *** National Eye Institute(NEI)provided the first round of research funding for its Audacious Goals Initiative(AGI)on visual neural regeneration in 2013 and the last round in ***,we focus on this *** sources included PubMed,the National science Foundation(NsF),the NEI,the Blue Ridge Institute for Medical Research and data from the major professional organization for eye and vision research,the Association for Research in Vision and Ophthalmology(ARVO).

关键词： neural visual Times

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Design of a cationic accelerator enabling ultrafast ion diffusion kinetics in aqueous zinc-ion batteries

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journal of Energy Chemistry 2025年第1期100卷 377-384页

作者： Yawei Xiao Qianqian Gu Haoyu li Mengyao li Yude Wang National Center for International Research on Photoelectric and Energy Materials School of Materials and Energy Yunnan University Key Laboratory of Ministry of Education for Advanced Materials in Tropical Island Resources School of Chemistry and Chemical Engineering Hainan University College of Chemical Engineering Fuzhou University Yunnan Key Laboratory of Carbon Neutrality and Green Low-carbon Technologies Yunnan University

Aqueous zinc-ion batteries are highly favored for grid-level energy storage owing to their low cost and high safety,but their practical application is limited by slow ion *** address this,a strategy has been developed to create a cation-accelerating electric field on the surface of the cathode to achieve ultrafast Zn2+diffusion *** employing electrodeposition to coat Mos2on the surface of BaV6O16·3H2O nanowires,the directional built-in electric field generated at the heterointerface acts as a cation accelerator,continuously accelerating Zn2+diffusion into the active *** optimized Zn2+diffusion coefficient in CC@BaV-6O16·3H2O@Mos2(7.5×10～8cm2s-1) surpasses that of most reported V-based ***,Mos2serving as a cathodic armor extends the cycling life of the Zn-CC@BaV6O16·3H2O@Mos2full batteries to over 10000 *** work provides valuable insights into optimizing ion diffusion kinetics for high-performance energy storage devices.

关键词： Internal electric field Cationic accelerator Ion diffusion kinetics Cathode modification strategy Aqueous zinc ion battery

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