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Management of difficult inflammatory bowel disease:where are we now?

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World Journal of Gastroenterology 2000年第3期6卷 315-323页

作者： d.s. Rampton Reader & Consultant Gastroenterologist Gastrointestinal Science Research Unit and Digestive Diseases Research CentreSt Bartholomews & Royal London School of Medicine and DentistryLondon E1 2ADUK

INTROdUCTION Medical care of patients with inflammatory bowel disease(IBd) comprise general measures and specific pharmacological,nutritional,endoscopic and surgical

关键词： inflammatory bowel diseases/therapy colitis/therapy Crohn disease/therapy endoscopy gastrointestinal social support azathioprine

Residual force enhancement in human skeletal muscles:A systematic review and meta-analysis

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Journal of sport and Health science 2022年第1期11卷 94-103页

作者： daiani de campos Lucas B.R.Orssatto Gabriel s.Trajano Walter Herzog Heiliane de Brito Fontana Biomechanics Laboratory Federal University of Santa CatarinaFlorianopolis 88040-001Brazil Faculty of Health School of Exercise and Nutrition SciencesQueensland University of TechnologyBrisbane QLD 4030Australia Human Performance Laboratory Faculty of KinesiologyUniversity of CalgaryAB T2N 1N4Canada school of Biological sciences Federal University of Santa CatarinaFlorianopolis 88040-900Brazil

Objective:We reviewed and appraised the existing evidence of in vivo manifestations of residual force enhancement in human skeletal muscles and assessed,through a meta-analysis,the effect of an immediate history of eccentric contraction on the subsequent torque capacity of voluntary and electrically evoked muscle ***:Our search was conducted from database inception to May *** information was extracted from,and quality was assessed for,45 ***-analyses and metaregressions were used to analyze residual torque enhancement and its dependence on the angular amplitude of the preceding eccentric ***:Procedures varied across studies with regards to muscle group tested,angular stretch amplitude,randomization of contractions,time window analyzed,and verbal *** capacity in isometric(constant muscle tendon unit length and joint angle)contractions preceded by an eccentric contraction was typically greater compared to purely isometric contractions,and this effect was greater for electrically evoked muscle contractions than voluntary *** torque enhancement differed across muscle groups for the voluntary contractions,with a significant enhancement in torque observed for the adductor pollicis,ankle dorsiflexors,ankle plantar flexors,and knee extensors,but not for the elbow and knee ***-regressions revealed that the angular amplitude of the eccentric contraction(normalized to the respective joints full range of motion)was not associated with the residual torque enhancement ***:There is evidence of residual torque enhancement for most,but not all,muscle groups,and residual torque enhancement is greater for electrically evoked than for voluntary *** to our hypothesis,and contrary to generally accepted findings on isolated muscle preparations,residual torque enhancement in voluntary and electrically evoked contractions does not seem to depend on the angular ampli

关键词： Cross-bridge theory Eccentric contraction Force-length relationship Isometric force Muscle properties

Electrical and optical properties of lithium borate glasses doped with Nd_2O_3

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Journal of Rare Earths 2012年第8期30卷 785-789页

作者： R.s. Gedam d.d. Ramteke department of Applied Physics Visvesvaraya National Institute of Technology

Glass series with general formula 25Li2O-（75-x）B2O3-xNd2O3 was prepared by conventional melt quench technique. Electrical and optical characterizations of these glasses were carried out. It was observed that conductivity of glasses decreased and activation energy in- creased with the addition of Nd2O3. The density and refractive index of the glasses increased while optical band gap and radiation length de- creased due to structural changes.

关键词： conductivity density refractive index optical absorption Tauc's plot rare earths

Luminescence properties of Gd^(3+) containing glasses for ultra-violet(UV) light

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Journal of Rare Earths 2014年第5期32卷 389-393页

作者： d.d.Ramteke R.s.Gedam department of Applied Physics Visvesvaraya National Institute of Technology

Effect of Gd2O3 addition on optical properties of 27.5 Li2O-72.5 B2O3 glass systems was studied. density, differential thermal analysis （dTA）, optical absorption spectra and luminescence technique were used to characterize the prepared glasses. Emis- sion spectra showed two band 6p7/2→8s7/2 （311.5 nm） and 6p5/2→8s7/2 （305 nm） under the excitation of 274 nm. The intense emission at 311.5 nm suggested that these glasses could be useful as source of narrowband UV light.

关键词： glasses rare earths absorption band gap luminescence UV light

AN IMPLEMENTATION OF THE COLLOCATION METHOd FOR INITIAL VALUE PROBLEMs

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International Journal of Modeling, simulation, and scientific Computing 2013年第2期4卷 142-154页

作者： RAFAEL G.campos FRANCIsCO dOM´INGUEZ MOTA Facultad de Ciencias Fısico-Matematicas Universidad Michoacana 58060 MoreliaMich.Mexico

An implementation of the standard collocation method based on polynomial interpolation is presented in a matrix framework in this *** underlying differentiation matrix can be partitioned to yield a superconvergent implicit multistep-like method to solve the initial value problem *** first-and second-order versions of this method are L-stable.

关键词： IVP OdE collocation differentiation matrix interpolation superconvergence stability

description of a Propulsion Unit Used in Guiding a Walking Machine by Recognizing a Three-point Bordered Path

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Chinese Journal of Mechanical Engineering 2016年第6期29卷 1157-1166页

作者： NUNEZ-ALTAMIRANO diego A JUAREZ-campos Ignacio MARQUEZ-PEREZ Lucia FLOREs-dIAZ Ociel school of Mechanical Engineering Universidad Michoacana de San Nicolas de Hidalgo Morelia Michoacan Mexico

A reconfigurable propulsion unit based on the Peaucellier-Lipkin mechanism has the ability to describe exact straight or curved paths depending on the selected ratio between the lengths of two of its links. The Peaucellier-Lipkin mechanism with one degree of freedom is transformed into a more sophisticated parallel kinematic chain by including four more degrees of freedom. The resulting propulsion unit is able to adapt its kinematic structure and reach instant centers of rotation, in accordance with the presence of three points that border a geometric path. A laser sensor mounted on the body of the machine detects each point. Once the machine has detected the exact location of the border of the road, it walks along a curve parallel to that border. Although the proposed research describes only one propulsion unit or leg, the methodology can be applied to all the legs of the walking machine. The novel 5-dOF leg is able to reach different centers of rotation, providing either the concave or convex arcs that satisfy the basic principle of displacement of walking machines.

关键词： Propulsion unit Peaucellier-Lipkin walking machine straight line mechanism.

dynamic responses of two buildings connected by viscoelastic dampers under bidirectional earthquake excitations

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Earthquake Engineering and Engineering Vibration 2014年第1期13卷 137-150页

作者： Z.d. Yang Eddie s.s. Lam department of Civil and Environmental Engineering The Hong Kong Polytechnic University

In this study,dynamic responses of two buildings connected by viscoelastic dampers under bidirectional excitations are extensively *** two buildings are a 10-story building and a 16-story building,with the shorter building on the *** dampers are installed at all fl oors of the shorter *** of motion are formulated using a fractional derivative model to represent the viscoelastic *** cases are considered with mass eccentricities at 0,10% and-10% with respect to the dimensions of the *** responses of the buildings are numerically predicted at different damper *** simulation results indicated that the maximum horizontal responses of the buildings without eccentricities are signifi cantly ***,torsional effects are adversely *** asymmetric buildings,the effectiveness of the connecting dampers is affected by building *** a result,mass eccentricities must be taken into account in damper *** compared with vibrations induced by unidirectional excitations,bidirectional excitations can increase the responses of coupled asymmetric *** addition,installing dampers only at the top fl oor of the shorter building may cause a sudden change in lateral stiffness of the taller ***,the story shear envelopes of the taller building are changed.

关键词： bidirectional excitations connecting dampers adjacent buildings fractional derivative

Performance of Chemical Vapor deposited Boron-doped AlN Thin Film as Thermal Interface Materials for 3-W LEd: Thermal and Optical Analysis

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Acta Metallurgica sinica(English Letters) 2018年第1期31卷 97-104页

作者： s. shanmugan d. Mutharasu Nano Optoelectronics Research Laboratory School of Physics Universiti Sains Malaysia (USM) 11800 Minden Pulau Pinang Malaysia

Boron-doped aluminum nitride （B-AlN） thin films were synthesized on Al substrates by using chemical vapor deposition method by changing the synthesis parameters and were used as thermal interface material for high power light emitting diode （LEd）. The B-AlN thin film-coated Al substrate was used as heat sink and studied the performance of high power LEd at various driving currents. The recorded transient cooling curve was evaluated to study the rise in junction temperature （Tj）, total thermal resistance （gth_tot） and the substrate thermal resistance （Rth_sub） of the given LEd. From the results, the B-AlN thin film （prepared at process 4） interfaced LEd showed low Rth-tot and Tj value for all driving currents and observed high difference in Rth_tot （△Rth_tot =2.2 K/W） at 700 mA when compared with the Rth-tot of LEd attached on bare Al substrates （LEd/Al）. The Tj of LEd was reduced considerably and observed 4.7 ℃ as ATj for the film prepared using process 4 condition when compared with LEd/Al boundary condition at 700 mA. The optical performance of LEd was also tested for all boundary conditions and showed improved lux values for the given LEd at 700 mA where B-AlN thin film was synthesized using optimized flow of Al, B and N sources with minimized B and N content. The other optical parameters such as color correlated temperature and color rendering index were also measured and observed low difference for all boundary conditions. The observed results are suggested to use B-AlN thin film as efficient solid thin film thermal interface materials in high power LEd.

关键词： Light emitting diode (LEd) B-AIN thin film Chemical vapor deposition (CVd) Thermal transient analysis Junction temperature Optical performance

Current and future perspectives in the management and treatment of colorectal cancer

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World Journal of Clinical Oncology 2025年第2期16卷 9-17页

作者： sigfredo E Romero-Zoghbi Evita Krumina Fernando López-campos Felipe Couñago department of Radiation Oncology GenesisCare Talavera de la ReinaToledo 45600Spain department of Radiation Oncology GenesisCare GuadalajaraGuadalajara 19004Spain department of Radiation Oncology Hospital Universitario Ramón Y CajalMadrid 28034Spain department of Radiation Oncology GenesisCare-Hospital Universitario Vithas Madrid La MilagrosaMadrid 28010Spain

In this editorial,we reviewed the article by Fadlallah et al that was recently published in the World Journal of Clinical *** article provided a comprehensive and in-depth view of the management and treatment of colorectal cancer(CRC),one of the leading causes of cancer-related morbidity and mortality *** article analyzed the therapeutic modalities and their sequencing,focusing on total neoadjuvant therapy for locally advanced rectal *** highlighted the role of immunotherapy in tumors with high microsatellite instability or deficient mismatch repair,addressing recent advances that have improved prognosis and therapeutic response in localized and metastatic *** in surgical techniques,advanced radiotherapy,and systemic agents targeting specific mutational profiles are also discussed,reflecting on how they revolutionized clinical *** tumor dNA has emerged as a promising tool for detecting minimal residual disease,prognosis,and therapeutic monitoring,solidifying its role in precision *** review emphasized the importance of technological and therapeutic advancements in improving clinical outcomes and personalizing CRC treatment.

关键词： Colorectal cancer Metastatic colorectal cancer Total neoadjuvant therapy Chemoradiotherapy Colon surgery Rectal surgery Chemotherapy Immunotherapy