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A synthesis of the Cretaceous wildfire record related to atmospheric oxygen levels?

Journal of Palaeogeography 2024年第1期13卷 149-164页

作者： Da-Wei Lü Wen-Xu Du Zhi-Hui Zhang Yuan Gao Tian-Tian Wang Jin-cheng Xu Ao-Cong Zhang cheng-shan Wang shandong Provincial Key Laboratory of Depositional Mineralization and sedimentary Minerals College of Earth Sciences and EngineeringShandong University of Science and TechnologyQingdao 266590Shandong ProvinceChina school of Earth sciences and Resources China University of GeosciencesBejing 100083China Institute of Earth sciences China University of Geosciences(Bejing)Beijing 100083China

The Cretaceous was a significant greenhouse period in Earth's history with higher atmospheric CO_(2) levels and temperatures than today. Although evidence of combustion has been widely described from the Cretaceous deposits, our understanding of the spatiotemporal diversification pattern and process of the Cretaceous wildfires is still limited. In this study, we comprehensively synthesize a total of 271 published Cretaceous wildfire occurrences based on the by-products of burning, including fossil charcoal, pyrogenic inertinite(fossil charcoal in coal), and pyrogenic polycyclic aromatic hydrocarbons(PAHs). spatially, the dataset shows a distinctive distribution of reported wildfire evidence characterized by high concentration in the middle latitudinal areas of the Northern Hemisphere(30°N-60°N) over the Cretaceous. Temporally, an overall increasing trend of the reported wildfire data from the Early Cretaceous to the Late Cretaceous is coincident with higher atmospheric O_(2) levels. However, the spatial and temporal patterns may result from many types of factors, such as taphonomy, preservation, and researcher biases, instead of a real picture of the Cretaceous wildfire evolution. To better understand the spatiotemporal diversification of the Cretaceous wildfire, more investigations on the record of wildfire occurrences during this period would be necessary in the future.

关键词： Wildfire Cretaceous Atmospheric oxygen Taphonomy Charcoal

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Accelerated aging and frailty in cardiovascular diseases

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Journal of Geriatric Cardiology 2024年第8期21卷 828-830页

作者： Xue-Hua cheng Tao WU Li HAN Department of Traditional Chinese Medicine Geriatrics Huadong Hospital Affiliated to Fudan UniversityShanghaiChina

Aging is the greatest risk factor for cardiovascular disease(CVD),which is the most common cause of death in European countries.[1]It is estimated that during the period from 2020 to 2022,there were 9.0%more excess deaths from CVD than expected.[2]by 2030,approximately 20%of the population will be aged 65 years and older,and CVD will account for 40%of deaths in this age group,[3]imposing a significant burden on the healthcare system and society as a *** is related to frailty,which represents the dynamic progression of physical and physiological decline in older *** limits an individual’s ability to recover from acute stressors and serves as a predictor of clinical adverse *** the uncertainties in screening,assessing,and managing frailty in clinical practice,emphasizing the connections between frailty,aging,and CVD will provide new insights for the prediction,prevention and management of CVD in the aging population.

关键词： aging prevention prediction

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small-diameter acellular porcine corneal stroma for peripheral corneal ulceration treatment

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International Journal of Ophthalmology(English edition) 2024年第5期17卷 831-837页

作者： Tian Liang Xia Wang Jie Wu Yan cheng Department of Ophthalmology Xi’an No.1 HospitalXi’an 710002Shaanxi ProvinceChina

AIM:To evaluate the clinical efficacy of small-diameter acellular porcine corneal stroma(sAPs)for the treatment of peripheral corneal ulceration(PCU).METHODs:This retrospective clinical study included 18 patients(18 eyes)with PCU between April 2018 and December *** patients had PCU and underwent lamellar keratoplasty with *** indicators included preoperative and postoperative best-corrected visual acuity(bCVA)and transparency of *** infection control rate in the surgical eye-lesion area was also ***:Eighteen patients underwent lamellar keratoplasty with sAPs to treat *** of the patients experienced rejection after 6mo(18/18)and 12mo(16/16)of *** bCVA(0.47±0.30)at the 6mo followup after operation was significantly improved compared with the baseline(0.99±0.80),and the difference was statistically significant(Z=-3.415,PbCVA at the 12mo follow-up after operation was not statistically significant compared to the 6mo(Z=0,P=1).With time,the sAPs graft gradually became *** the 6mo(18/18)and 12mo(16/16)follow-up,none of the patients had recurrent corneal ***:sAPs is clinically effective in the treatment of PCU,improving the patient’s bCVA and reducing the incidence of rejection after keratoplasty.

关键词： acellular porcine corneal stroma lamellar keratoplasty infectious corneal ulcer

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New insight into the role of exosomes in idiopathic membrane nephropathy

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bIOCELL 2024年第1期48卷 21-32页

作者： JIANHONG LIU KAI HE HAN WANG XIAOHONG cheng Department of Nephrology Shaanxi Provincial Hospital of Traditional Chinese MedicineXian710000China school of basicMedical sciences and state Key Laboratory of southwestern Chinese Medicine Resources Chengdu University of Traditional Chinese MedicineChengdu611137China Department of Pathophysiology West China College of Basic Medical Sciences&Forensic MedicineSichuan UniversityChengdu610041China

Exosomes,nanoscale extracellular vesicles(EVs)derived from the invagination of the endosomal membrane,are secreted by a majority of cell *** carriers of DNA,mRNA,proteins,and microRNAs,exosomes are implicated in regulating biological activities under physiological and pathological ***-derived exosomes,which vary in origin and function,may either contribute to the pathogenesis of disease or represent a potential therapeutic *** nephropathy(MN),an autoimmune kidney disease characterized by glomerular damage,is a predominant cause of nephrotic ***,MN,especially idiopathic membranous nephropathy(IMN),often results in end-stage renal disease(EsRD),affecting approximately 30%of patients and posing a considerable economic challenge to healthcare *** substantial research,therapeutic options remain ineffective at halting IMN progression,underscoring the urgent need for innovative *** evidence has implicated exosomes in IMN’s pathophysiology;Providing a fresh perspective for the discovery of novel biomarkers and therapeutic *** review aims to scrutinize recent developments in exosome-related mechanisms in IMN and evaluate their potential as promising therapeutic targets and diagnostic biomarkers,with the hope of catalyzing further investigations into the utility of exosomes in MN,particularly IMN,ultimately contributing to improved patient outcomes in these challenging disease settings.

关键词： Exosomes biomarkers Membranous nephropathy Therapeutic targets

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shale Fracturability Graphic Template based onMixed Analytic Hierar-chy Process andMutation Theory

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Energy Engineering 2024年第7期121卷 1921-1943页

作者： sichen Li Dehua Liu Liang cheng Pan Ma College of Petroleum Engineering Yangtze UniversityWuhan430100China Hubei Drilling and Recovery Engineering for Oil and Gas Key Laboratory Wuhan430100China

Due to the depletion of conventional energy reserves,there has been a global shift towards non-conventional energy *** oil and gas have emerged as key *** resources have dense and heterogeneous reservoirs,which require hydraulic fracturing to *** process depends on identifying optimal fracturing layers,also known as‘sweet spots’.However,there is currently no uniform standard for locating these sweet *** paper presents a new model for evaluating fracturability that aims to address the current gap in the *** model utilizes a hierarchical analysis approach and a mutation model,and is distinct in its use of original logging data to generate a fracturability evaluation *** this paper’s shale fracturing sweet spot evaluation method based on a two-step mutation model,four wells in different blocks of Fuling and Nanchuan Districts in China were validated,and the results showed that the proportion of high-yielding wells on the sweet spot line could reach 97.6%,while the proportion of low-producing wells was only 78.67%.Meanwhile,the evaluation results of the model were compared with the microseismic data,and the matching results were consistent.

关键词： shale reservoir hydraulic fracturing analytic hierarchy process mutation model microseismic

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Progranulin:A promising biomarker and therapeutic target for fibrotic diseases

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Acta Pharmaceutica sinica b 2024年第8期14卷 3312-3326页

作者： Fan Yang Ming-Han cheng Hai-Feng Pan Jian Gao Pediatric Translational Medicine Institute Shanghai Children’s Medical CenterSchool of MedicineShanghai Jiao Tong UniversityShanghai 200000China Department of Ophthalmology the First Affiliated Hospital of Anhui Medical UniversityHefei 230022China Department of Epidemiology and biostatistics School of Public HealthAnhui Medical UniversityHefei 230022China Inflammation and Immune Mediated Diseases Laboratory of Anhui Province Hefei 230022China

Progranulin(PGRN),a multifunctional growth factor-like protein expressed by a variety of cell types,serves an important function in the physiologic and pathologic processes of fibrotic diseases,including wound healing and the inflammatory *** was discovered to inhibit proinflammation effect by competing with tumor necrosis factor-alpha(TNF-a)binding to TNF ***,excessive tissue repair in the development of inflammation causes tissue *** investigations have indicated the significance of PGRN in regulating inflammatory ***,multiple studies have shown that PGRN was linked to fibrogenesis,and was considered to monitor the formation of fibrosis in multiple organs,including liver,cardiovascular,lung and *** paper is a comprehensive review summarizing our current knowledge of PGRN,from its discovery to the role in *** is followed by an in-depth look at the characteristics of PGRN,consisting of its structure,basic function and intracellular ***,we will discuss the potential of PGRN in the diagnosis and treatment of fibrosis.

关键词： Progranulin Fibrotic disease Fibrosis Inflammation biomarker Therapeutic target PGRN/TNFR interaction signaling pathway

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Transformer-based Cloud Detection Method for High-Resolution Remote sensing Imagery

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Computers, Materials & Continua 2024年第7期80卷 661-678页

作者： Haotang Tan song sun Tian cheng Xiyuan shu Key Laboratory of GIs Application Research School of Geography and TourismChongqing Normal UniversityChongqing401331China College of Computer and Information science Chongqing Normal UniversityChongqing401331China Department of Military Installations Army Logistics AcademyChongqing401331China

Cloud detection from satellite and drone imagery is crucial for applications such as weather forecasting and *** the limitations of conventional convolutional neural networks,we propose an innovative transformer-based *** method leverages transformers,which are adept at processing data sequences,to enhance cloud detection ***,we introduce a Cyclic Refinement Architecture that improves the resolution and quality of feature extraction,thereby aiding in the retention of critical details often lost during cloud *** extensive experimental validation shows that our approach significantly outperforms established models,excelling in high-resolution feature extraction and precise cloud *** integrating Positional Visual Transformers(PVT)with this architecture,our method advances high-resolution feature delineation and segmentation ***,our research offers a novel perspective for surmounting traditional challenges in cloud detection and contributes to the advancement of precise and dependable image analysis across various domains.

关键词： Cloud transformer image segmentation remotely sensed imagery pyramid vision transformer

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Evaluation method for electromagnetic interference complexity of high voltage switch based on feature extraction and GCC-GRU network

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HIGH VOLTAGE 2024年第3期9卷 749-761页

作者： Lu, Wenchao Duan, Jiandong cheng, Lin Lu, Jiangping Tao, Jiaxin Yin, Jianning Xian Univ Technol Sch Elect Engn Xian Peoples R China state Grid shaanxi Elect Power Co Ltd Power Res Inst Xian Peoples R China

When some new-type sensors are subjected electromagnetic interference (EMI), the traditional standard can no longer serve as the guidance for their EMI protection. Therefore, it is necessary to evaluate the complexity of the new sensing equipment's suffering from electromagnetic interference. A hybrid method of feature extraction and complexity evaluation of Electromagnetic Interference signals based on generalised correntropy criterion (GCC) is proposed. First, a variational mode decomposition algorithm for adaptive extraction of decomposed signals is constructed using GCC, and Generalised s-transform is used for processing and reorganisation. Then, according to the time-frequency space model, a new quantitative evaluation criterion interference factor is proposed, which overcomes the shortcomings of the traditional qualitative classification and the inability to solve the cross classification of indicators. Then, the Gated Recurrent Unit is introduced, and the GCC-GRU evaluation model with GCC as the loss function is derived. The authors conduct EMI tests and measured signal evaluation with Medium Voltage and High Voltage switches, and the results show that the method proposed is correct and effective.

关键词： EMPIRICAL MODE DECOMPOsITION EQUIPMENT sPECTRUM

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superhydrophobic Co/Fe sulfide nanoparticles and single-atoms doped carbon nanosheets composite air cathode for high-performance zinc-air batteries

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Journal of Energy Chemistry 2024年第9期96卷 568-577页

作者： Yan Tan Yijie Wang Aoshuang Li Xiucai Jiang Yuzhong Zhang Chuanwei cheng shanghai Key Laboratory of special Artificial Microstructure Materials and Technology School of Physics Science and EngineeringTongji UniversityShanghai 200092China

Development of a high-performance bifunctional catalyst is essential for the actual implementation of zinc-air batteries in practical ***,a bifunctional cathode of Co_(3)s_(4)/Fes heterogeneous nanoparticles embedded in Co/Fe single-atom-loaded nitrogen-doped carbon nanosheets is ***-iron sulfides and single atomic sites with Co-N_(4)/Fe-N_(4)configurations are confirmed to coexist on the carbon matrix by EXAFs spectroscopy.3D self-supported super-hydrophobic multiphase composite cathode provides abundant active sites and facilitates gas–liquid-solid three-phase interface reactions,resulting in excellent electrocatalytic activity and batteries performance,i.e.,an OER overpotential(η_(10))of 260 mV,a half-wave potential(E_(1/2))of 0.872 V for ORR,aΔE of 0.618 V,and a discharge power density of 170 mW cm^(−2),a specific capacity of 816.3 mAh g^(−1).DFT analysis shows multiphase coupling of sulfide heterojunction through single-atomic metal doped carbon nanosheets reduces offset on center of electronic density of states before and after oxygen adsorption,and spin density of adsorbed oxygen with same spin orientation,leading to weakened charge/spin interactions between adsorbed oxygen and substrate,and a lowered oxygen adsorption energy to accelerate OER/ORR.

关键词： Zn-air battery superhydrophobic interface Metal sulfide Heterostructure spin density

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Ultra-high sensitivity fiber optic microphone with corrugated graphene-oxide diaphragm for voice recognition

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Nano Research 2024年第8期17卷 7593-7602页

作者： Yang Liu cheng Li Lingxiao Yu Zhengwei Wu shangchun Fan Ruitao Lv school of Instrumentation and Optoelectronic Engineering Beihang UniversityBeijing 100191China shenzhen Institute of beihang University Shenzhen 518063China Key Laboratory of Advanced Materials(MOE) School of Materials Science and EngineeringTsinghua UniversityBeijing 100084China Aerospace Information Research Institute Chinese Academy of SciencesBeijing 100190China

To avoid interference from unexpected background noises and obtain high fidelity voice signal,acoustic sensors with high sensitivity,flat frequency response,and high signal-to-noise ratio(sNR)are urgently needed for voice ***(GO)has received extensive attention due to its advantages of controllable thickness and high fracture ***,low mechanical sensitivity(sM)introduced by undesirable initial stress limits the performance of GO material in the field of voice *** alleviate the aforementioned issue,GO diaphragm with annular corrugations is *** means of the reusable copper mold machined by picosecond laser,the fabrication and transfer of corrugated GO diaphragm are realized,thus achieving a Fabry–Perot(F–P)acoustic *** from the structural advantage of the corrugated GO diaphragm,our F–P acoustic sensor exhibits high s_(M)(43.70 nm/Pa@17 kHz),flat frequency response(−3.2 to 3.7 db within 300–3500 Hz),and high sNR(76.66 db@1 kHz).In addition,further acoustic measurements also demonstrate other merits,including an excellent frequency detection resolution(0.01 Hz)and high time stability(output relative variation less than 6.7% for 90 min).Given the merits presented before,the fabricated F–P acoustic sensor with corrugated GO diaphragm can serve as a high-fidelity platform for acoustic detection and voice *** conjunction with the deep residual learning framework,high recognition accuracy of 98.4%is achieved by training and testing the data recorded by the fabricated F–P acoustic sensor.

关键词： corrugated graphene-oxide(GO)diaphragm Fabry-Perot(F-P)acoustic sensor mechanical sensitivity voice recognition

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