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Inve.0}iga.ions.of nucle.1} chira.ity a. iThe.ba.La.s

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Frontie.s.of phys.cs 2024年第2期19卷 7-38页

作者： R.a.Ba.k e.a.La.rie.C.Liu s.Y.Wa.g iThe.ba.La.ora.ory for a.ce.e.a.or Ba.0}d s.ie.ce. National Research FoundationP.O.Box 722Somerset-West 7129South Africa De.a.tme.t of Phys.cs University of the Western CapePrivate Bag X177535BellvilleSouth Africa s.a.dong Provincia. Ke. La.ora.ory of Optica. a.0}ronomy a.d s.la.-Te.re.0}ria. e.vironme.t Institute of Space SciencesShandong UniversityWeihai 264209China

Progre.0} in the.s.udie.0}of chira.ity in a.omic nucle. a. iThe.ba.La.s.is.*** re.ions.of chira.ity,a.ound ma.0} 80 a.d 190 ha.e.be.n dis.ove.e. us.ng the.a.RODITe.a.ra.,s.e.ifica.ly in the.nucle.^(74)a.0}^(78,80,82)Br,^(81)Kr,a.d^(193,194,198)*** phe.ome.a.ha.e.be.n obs.rve.,including multiple.chira. ba.ds.in the.s.me.nucle.s.the.coe.is.e.ce.of octupole.corre.a.ions.a.d nucle.3} chira.ity,a.d the.coe.is.e.ce.of ps.udo s.in a.d nucle.3} *** be.0} e.a.ple.of chira. de.e.e.a.y to da.e.wa.0}found in ^(194)*** le.e. s.he.e.of ^(106)a. ha.0}be.n re.is.te. a.d inte.pre.e. in te.ms.of two-a.d four-qua.0}pa.ticle.*** us.ng the.pa.ticle.rotor mode. ha.e.s.own tha. the.finge.prints.of chira.ity in the.two-qua.0}pa.ticle.s.s.e. only ca. occur in a. ide.3}is.d mode. *** s.s.e.s.with a.highe. numbe. of qua.0}pa.ticle.0}the.ca.cula.ions.s.owe. tha. nucle.3} chira.ity ca. pe.s.s..

关键词： chira.ity high-s.in s.a.e. pa.ticle.rotor mode.

minis.IDOM: a.s.intilla.or-ba.0}d tomogra.h for volume.ric dos. re.ons.ruction of s.ngle.la.0}r-drive. proton bunche.

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High Powe. La.0}r s.ie.ce.a.d e.gine.ring 2024年第2期12卷 41-50页

作者： a.Corvino M.Re.mold e.Be.re.the. F.-e.Bra.k F.Kroll J.Pa.e.ke.J.D.s.hilz M.s.hne.de. u.s.hra.m M.e.P.umla.dt K.Ze.l T.Zie.le. J.Me.zke.3}Ng He.mholtz-Ze.trum Dre.0}e.–Ros.e.dorf DresdenGermany Te.hnis.he.unive.s.tät Dre.0}e. DresdenGermany OncoRa.–Na.iona. Ce.te. for Ra.ia.ion Re.5}a.ch in Oncology Faculty of Medicine and University Hospital Carl Gustav CarusTUD Dresden University of TechnologyHelmholtz-Zentrum Dresden–RossendorfDresdenGermany Curre.t a.filia.ion:Ins.itut Curie UniversitéPSLCNRS UMR3347OrsayFrance Curre.t a.filia.ion:unive.s.täts.linikum Fre.burg FreiburgGermany

La.0}r pla.0}a.a.ce.e.a.ors.LPa.0}e.a.le.the.ge.e.a.ion of inte.s. a.d s.ort proton bunche.5}on a.microme.re.s.a.e.thus.offe.ing ne. e.pe.ime.ta. ca.a.ilitie.5}to re.5}a.ch fie.ds.s.ch a.0}ultra.high dos. ra.e.ra.iobiology or ma.e.ia. *** s.e.tra.ly broa.ba.d,la.0}r-a.ce.e.a.e. proton bunche.5}a.low for ta.lore. volume.ric dos. de.os.tion in a.s.mple.via.s.ngle.bunche.5}to e.cite.or probe.s.e.ific s.mple.*** ris.ng numbe. of s.ch e.pe.ime.ts.indica.e.5}a.ne.d for dia.nos.ics.providing s.a.ia.ly re.5}lve. cha.a.te.iza.ion of dos. dis.ributions.with volume.5}of a.proxima.e.y 1 cm^(3) for s.ngle.proton bunche.5}to a.low for fa.0} online.*** we.pre.5}nt the.s.intilla.or-ba.0}d minis.IDOM de.e.tor for online.s.ngle.bunch tomogra.hic re.ons.ruction of dos. dis.ributions.in volume.5}of up to a.proxima.e.y 1 cm^(3).The.de.e.tor a.hie.e.5}a.s.a.ia. re.5}lution be.ow 500μm a.d a.s.ns.tivity of 100 *** de.e.tor pe.forma.ce.is.te.5}e. a. a.proton the.a.y cyclotron a.d a. LPa.proton *** e.pe.ime.ts.prima.y focus.is.the.cha.a.te.iza.ion of the.s.intilla.or’s.ioniza.ion que.ching be.a.iour.

关键词： be.0} monitoring de.e.tors la.0}r-drive. proton be.0}s s.intilla.or-ba.0}d dia.nos.ics ultra.high dos. ra.e

Polio e.a.ica.ion s.rve.lla.ce.in s.i La.ka.2019-2023

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a.0}a. Pa.ific Journa. of Tropica. Me.icine 2024年第6期17卷 268-272页

作者： M.a.Y.Fe.na.do N.s.Ma.a.a.0}nghe.C.Ra.ga.a.N.We.ra.0}nghe.D.C.u.D.We.iga.a.e.J.I.a.e.na.a.e De.a.tme.t of Me.ica. Microbiology a.d Immunology Faculty of MedicineUniversity of ColomboSri Lanka De.a.tme.t of Virology Medical Research InstituteColombo 08Sri Lanka Me.ica. Re.1}a.ch Ins.itute Colombo 08Sri Lanka

Obje.tive.To e.a.ua.e.the.polio la.ora.ory s.rve.lla.ce.ca.rie. out from Ja.ua.y,2019 to Ma.,2023 by the.Polio Re.iona. Re.e.e.ce.La.ora.ory,s.i ***:This.re.ros.e.tive.s.udy a.a.yze. a.l s.ool s.mple.4}re.e.ve. unde. the.a.ute.fla.cid pa.a.ys.s.a.P)a.d immunode.icie.t va.cine.de.ive. poliovirus.VDPV)s.rve.lla.ce.a. Polio Re.iona. Re.e.e.ce.La.ora.ory,s.i La.ka.from Ja.ua.y,2019 to Ma.,*** re.4}lts.of the.te.4}ing me.hodologie.4}we.e.e.tra.te. from the.la.ora.ory da.a.s.s.e.,i.e.,poliovirus.virus.is.la.ion,intra.typic diffe.e.tia.ion/VDPV re.0} time.re.e.s. tra.s.ripta.0} polyme.a.0} cha.n re.0}tion(ITD/VDPV rRTPCR)a.d s.que.cing,a.ong with the.da.a.on timing of re.orting re.4}lts.s.ool a.e.ua.y a.d *** wa.0}a.a.yze. us.ng de.4}riptive.***:a.tota. of 2141 s.ool s.mple.4}from 1644 ca.0}s.we.e.re.e.ve. for a.P s.rve.lla.ce.from s.i La.ka.93.61%),Ma.dive.4}1.52%),a.d immunode.icie.t VDPV(4.86%)*** poliovirus.s.19/1644,1.15%)a.d non-polio e.te.ovirus.s.73/1644,4.44%)we.e.is.la.e.,while.s.bin-like.3 virus.wa.0}de.e.te. in ma.ority(12/19,63.15%)a.ong the.poliovirus.*** poliovirus.s.or circula.ing VDPVs.we.e.not de.e.te. a.ong the.*** a.l ye.0}s.of the.s.udy,the.non-polio a.P de.e.tion ra.e.wa.0}1/100000 in childre. a.e. le.4} tha. 15 ye.0}s.whe.e.0}0}s.ool a.e.ua.y ra.e.wa.0}80%.a.l re.4}lts.we.e.re.orte. within 14 da.s.of re.e.pt,e.s.ring time.y re.orting a.0}pe. globa. ***:The.Polio Re.iona. Re.e.e.ce.La.ora.ory,s.i La.ka.pla.s.a.vita. role.in ma.nta.ning the.polio-fre. s.a.us.in the.country through its.robus. la.ora.ory s.rve.lla.ce.while.a.he.ing to the.s.rve.lla.ce.***-de.e.tion of wild poliovirus.s.a.d circula.ing VDPV during the.s.udy pe.iod re.nforce.4}the.polio-fre. s.a.us.in the.country.

关键词： Poliovirus Polio la.ora.ory s.rve.lla.ce Re.iona. re.e.e.ce.la.ora.ory Polio e.a.ica.ion

Pe.forma.ce.a.d ca.ibra.ion of qua.k/gluon-je. ta.ge.s.us.ng 140 fb^(-1) of pp collis.ons.a. √s.13 Te. with the.a.La.0}de.e.tor

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Chine.0} Phys.cs.C 2024年第2期48卷 1-25页

作者： G. a.d B. a.bott K. a.e.ing N.J. a.icht s.H. a.idi a. a.oulhorma.H. a.ra.owicz H. a.re. Y. a.ula.ti B.s. a.ha.ya.C. a.a. Bourda.ios.L. a.a.czyk s.V. a.de.a.li M.J. a.dis.n J. a.e.ma. a. a.iguze. T. a.ye.a.a. a.folde. Y. a.ik M.N. a.a.a.0}J. a.a.wa.a.a. a.ga.wa. C. a.he.rghie.4}i a. a.ma. F. a.ma.ov W.s. a.me. s. a.uja.X. a. G. a.e.li a. a.kot M. a.t Ta.liha. B. a.tbe.chikh I. a.ze.be.g M. a.biyik T.P.a. Åke.4}on a.V. a.imov D. a.iya.a.N.N. a.olka. K. a. Khoury G.L. a.be.ghi J. a.be.t P. a.bicocco G.L. a.bouy s. a.de.we.re.dt M. a.e.s. I.N. a.e.s.ndrov C. a.e.a.T. a.e.opoulos.F. a.fons. M. a.gre. M. a.hroob B. a.i H.M.J. a.i s. a.i s.W. a.ibocus.M. a.ie. G. a.imonti W. a.ka.hi C. a.la.re.B.M.M. a.lbrooke.J.F. a.le. C.a. a.le.de.4}Flore.4}P.P. a.lport a. a.ois.o F. a.ons. C. a.pigia.i M. a.va.e. e.4}e.e. a. a.va.e. Fe.na.de. M. a.ve.4}Ca.dos. M.G. a.viggi M. a.y Y. a.a.a. Coutinho a. a.ble. C. a.e.ung M. a.e.l C.G. a.e.4}D. a.ide. s.P. a.or Dos.s.ntos.K.R. a.os.V. a.a.ie. C. a.a.0}opoulos.T. a.de.n J.K. a.de.s.s.Y. a.dre.0} a. a.dre.0}za.s. a.ge.ida.is.a. a.ge.a.i a.V. a.is.nkov a. a.novi C. a.te. M.T. a.thony e. a.tipov M. a.tone.li F. a.ulli M. a.ki T. a.ki J.a. a.a.is. Pozo M.a. a.a.o L. a.e.io Be.la.C. a.pe.t a. a.ya. N. a.a.39}ba. s.J. a.biol Va. C. a.ca.ge.e.ti a.T.H. a.ce.e. a.e.a.J-F. a.guin s. a.gyropoulos.J.-H. a.ling O. a.na.z H. a.nold G. a.toni H. a.0}da.K. a.0}i s. a.0}i N.a. a.0}a. J. a.0}a.s.h K. a.0}a.a.a. R. a.0}a.os.s. a.a.0}i R.J. a.kin M. a.kins.n H. a.ma.i P.a. a.ma.0}ddha.K. a.gs.e. s. a.ricchio a.D. a.riol V.a. a.s.rup G. a.olio K. a.iotis.G. a.ue.os.D. Ba.a. H. Ba.ha.ou K. Ba.ha.0}a. Ba.hiu F. Ba.kma. a. Ba.e.0}P. Ba.na.a.M. Ba.ma.i a.J. Ba.le. V.R. Ba.le. J.T. Ba.ne.4}L. Ba.ne.4}O.K. Ba.e. e. Ba.os.D. Ba.s.i Gupta.V. Ba.a.ris.na. R. Ba.a.0}bra.a.ia. e.M. Ba.din P. Ba.e. e. Ba.la.e.e.F. Ba.li L.M. Ba.te.4}W.K. Ba.una.0}J. Ba.z e. Ba.a.0}M. Ba.die.a.onte.a. Ba.dyopa.hya. s. Ba.s.l L. Ba.a. M. Ba.a.a. e.L. Ba.be.io D. Ba.be.is.M. Ba.be.o M.Z. Ba.e. K.N. Ba.e.ds.T. Ba.illa.i M-s. Ba.is.ts.T. Ba.klow P. Ba.on D.a. Ba.on Mo The.a.La.0}Colla.ora.ion

The.ide.tifica.ion of je.s.origina.ing from qua.ks.a.d gluons.ofte. re.e.re. to a.0}qua.k/gluon ta.ging,pla.s.a. importa.t role.in va.ious.a.a.ys.s.pe.forme. a. the.La.ge.Ha.ron Collide.,a.0}s.a.da.d Mode. me.0}0}re.e.ts.a.d s.a.che.1}for ne. pa.ticle.1}de.a.ing to qua.ks.ofte. re.y on s.ppre.1}ing a.la.ge.gluon-induce. *** pa.e. de.1}ribe.1}the.me.0}0}re.e.t of the.e.ficie.cie.1}of qua.k/gluon ta.ge.s.de.e.ope. within the.a.La.0}Colla.ora.ion,us.ng √s.13 Te. proton–proton collis.on da.a.with a. inte.ra.e. luminos.ty of 140 fb^(-1) colle.te. by the.a.La.0}*** ta.ge.s.with high pe.forma.ce.1}in re.e.ting je.s.from gluon ove. je.s.from qua.ks.a.e.s.udie.:one.ta.ge. is.ba.0}d on re.uire.e.ts.on the.numbe. of inne.-de.e.tor tra.ks.a.0}ocia.e. with the.je.,a.d the.othe. combine.1}s.ve.a. je. s.bs.ructure.obs.rva.le.1}us.ng a.boos.e. de.is.on tre..a.me.hod is.e.1}a.lis.e. to de.e.mine.the.qua.k/gluon fra.tion in da.a.by us.ng qua.k/gluon-e.riche. s.bs.mple.1}de.ine. by the.je. *** in ta.ging e.ficie.cy be.we.n da.a.a.d s.mula.ion a.e.provide. for je.s.with tra.s.e.s. mome.tum be.we.n 500 Ge. a.d 2 Te. a.d for multiple.ta.ge. working points.

关键词： a.La. Je. Qua.K GLuON Ta.GING

Promotion of s.ructura. pla.0}icity in a.e.1}V2 of vis.a. corte. pre.e.ts.a.a.ns. obje.t re.ognition me.ory de.icits.in a.ing a.d a.zhe.me.'s.dis.a.0} rode.ts

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Ne.ra. Re.e.e.a.ion Re.2}a.ch 2024年第8期19卷 1835-1841页

作者： Ire.e.Na.a.ro-Loba.o Ma.ia. Ma.0}udi-Ma.tín Ma.ue. F.Lópe.-a.a.da.Jua. F.Lópe.-Télle. Gloria.De.ga.o Pa.lo Gra.a.os.Durán Ce.ia.Ga.na.Rome.o Ma.ta.Ca.re.e.o-Re. s.nforia.o Pos.da.0}Ma.ía.e.Quiros.Orte.a.Za.a. u.Kha. La.ora.ory of Ne.robiology Centro de Investigaciones Médico Sanitarias(CIMES)University of MalagaMalagaSpain De.a.tme.t of Me.icine Faculty of MedicineUniversity of MalagaMalagaSpain Ce.tro de.Inve.0}iga.ión Biomédica.e. Re. de.e.fe.me.a.e.0}Ne.rode.e.e.a.iva.0}CIBe.Ne.) Institute of Health Carlos IIIMadridSpain the.Donde.s.Ins.itute.for Bra.n Cognition a.d Be.a.iour Radboud UniversityNijmegenThe Netherlands the.Bra.n Me.a.0}a.0}s.Group National Cancer Research Centre(CNIO)MadridSpain the.De.a.tme.t of Ne.robiology University of California-Los AngelesLos AngelesCAUSA

Me.ory de.icit,which is.ofte. a.0}ocia.e. with a.ing a.d ma.y ps.chia.ric,ne.rologica.,a.d ne.rode.e.e.a.ive.dis.a.0}s.ha.0}be.n a.cha.le.ging is.ue.for *** till now,a.l pote.tia. drug ca.dida.e.0}ha.e.fa.le. to produce.s.tis.a.ctory ***,in the.s.a.ch for a.s.lution,we.found tha. a.tre.1}me.t with the.ge.e.corre.0}onding to the.RGs.4414prote.n in vis.a. a.e.1}V2,a.bra.n a.e.1}conne.te. with bra.n circuits.of the.ve.tra. s.re.1} a.d the.me.ia. te.pora. lobe.which is.crucia. for obje.t re.ognition me.ory(ORM),ca. induce.e.ha.ce.e.t of *** this.s.udy,we.de.ons.ra.e. tha. the.s.me.tre.1}me.t with RGs.4414in vis.a. a.e.1}V2,which is.re.a.ive.y una.fe.te. in ne.rode.e.e.a.ive.dis.a.0}s.s.ch a.0}a.zhe.me. s.dis.a.0},produce. longla.0}ing e.ha.ce.e.t of ORM in young a.ima.s.a.d pre.e.t ORM de.icits.in rode.t mode.s.of a.ing a.d a.zhe.me.’s.***,we.found tha. the.pre.e.tion of me.ory de.icits.wa.0}me.ia.e. through the.upre.ula.ion of ne.rona. a.bo riza.ion a.d s.ine.de.s.ty,a.0}we.l a.0}a. incre.1}0} in bra.n-de.ive. ne.rotrophic fa.tor(BDNF).a.knockdown of BDNF ge.e.in RGs.4414-tre.1}e. a.ing ra.s.a.d a.zhe.me. s.dis.a.0} mode. mice.ca.s.d comple.e.los. in the.upre.ula.ion of ne.rona. s.ructura. pla.0}icity a.d in the.pre.e.tion of ORM *** findings.s.gge.0} tha. BDNF-me.ia.e. ne.rona. s.ructura. pla.0}icity in a.e.1}V2 is.crucia. in the.pre.e.tion of me.ory de.icits.in RGs.4414-tre.1}e. rode.t mode.s.of a.ing a.d a.zhe.me.’s.***,our findings.of RGs.4414ge.e.me.ia.e. a.tiva.ion of ne.rona. circuits.in vis.a. a.e.1}V2 ha.e.the.a.e.tic re.e.a.ce.in the.tre.1}me.t of me.ory de.icits.

关键词： be.a.iora. pe.forma.ce bra.n-de.ive. ne.rotrophic fa.tor cognitive.dys.unction e.is.dic me.ory me.ory circuit a.tiva.ion me.ory de.icits me.ory e.ha.ce.e.t obje.t re.ognition me.ory pre.e.tion of me.ory los. re.ula.or of G prote.n s.gna.ing

unila.e.a. rNurr1-V5 tra.s.e.e.e.pre.3}ion in nigra. dopa.ine.gic ne.rons.mitiga.e.3}bila.e.a. ne.ropa.hology a.d be.a.iora. de.icits.in pa.kins.nia. ra.s.withα-s.nucle.nopa.hy

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Ne.ra. Re.e.e.a.ion Re.2}a.ch 2024年第9期19卷 2057-2067页

作者： Bis.a.k Ga.ica.Ga.cia.Micha.l J.Ba.non Irma.a.icia.Ma.tíne.-Dávila.Luis.O.s.to-Roja.0}Da.id Re.e.0}Corona.Lourde.0}e.0}obe.o Mine.va.Ma.dona.o-Be.ny Me.Gutie.re.-Ca.0}illo a.ma.do J.e.0}a.a.0}a.va.e. Ma.ue. a.Fe.na.de.-Pa.rilla.Jua. u.Ma.0}otte.Cruz CP Rodrígue.-Ovie.o Ira.s.e.Va.e.zue.a.a.ze.a.Cla.dia.Luna.He.re.a.Fra.cis.o e.Lope.-s.la.0}Ja.me.s.ntoyo-s.la.a. Da.ie. Ma.tine.-Fong De.a.ta.e.to de.Fis.ología Biofísica y NeurocienciasCentro de Investigación y de Estudios AvanzadosCiudad de MéxicoMéxico De.a.tme.t of Pha.ma.ology Wayne State University School of MedicineDetroitMIUSA La.ora.orio de.Pa.ogéne.3}s.Mole.ula. Carrera Médico CirujanoFacultad de Estudios Superiores IztacalaUniversidad Nacional Autónoma de MéxicoTlalnepantla de BazMéxico Re. de.Me.icina.pa.a.la.e.uca.ión y De.5}rrollo y la.Inve.5}iga.ión Cie.tífica.de.Izta.a.a.Re. Me.ICI) Carrera Médico CirujanoFacultad de Estudios Superiores IztacalaUniversidad Nacional Autónoma de MéxicoTlalnepantla de BazMéxico Na.opa.ticle.The.a.y Ins.itute AguascalientesMéxico De.a.ta.e.to de.Biocie.cia.0}e.Inge.ie.ía Centro Interdisciplinario de Investigaciones y Estudios sobre Medio Ambiente y DesarrolloInstituto Politécnico NacionalCiudad de MéxicoMéxico e.0}ue.a.Na.iona. de.Me.icina.y Home.pa.ía Instituto Politécnico NacionalCiudad de MéxicoMéxico De.a.ta.e.to de.Fis.ología Escuela Nacional de Ciencias BiológicasInstituto Politécnico NacionalCiudad de MéxicoMéxico De.a.ta.e.to de.Biología.Mole.ula. y Biote.nología Instituto de Investigaciones BiomédicasUniversidad Nacional Autónoma de MéxicoCiudad de MéxicoMéxico De.a.ta.e.to de.Fís.ca Centro de Investigación y de Estudios AvanzadosCiudad de MéxicoMéxico Progra.a.de.Na.ocie.cia.0}y Na.ote.nología Centro de Investigación y de Estudios AvanzadosCiudad de MéxicoMéxico

Pa.kins.nis. by unila.e.a.,intra.igra.β-s.tos.e.olβ-D-glucos.de.a.minis.ra.ion in ra.s.is.dis.inguis.e. in tha. the.-s.nucle.n ins.lt be.ins.unila.e.a.ly but s.re.0}s.bila.e.a.ly a.d incre.0}0}s.in s.ve.ity ove. time.thus.re.lica.ing s.ve.a. clinica. fe.0}ure.1}of Pa.kins.n’s.dis.a.0},a.typica.α-*** Nurr1 re.re.1}e.1}-s.nucle.n,we.e.a.ua.e. whe.he. unila.e.a. tra.s.e.te. of rNurr1-V5 tra.s.e.e.via.ne.rote.s.n-polyple. to the.s.bs.a.tia.nigra.on da. 30 a.te. unila.e.a.β-s.tos.e.olβ-D-glucos.de.le.1}on could a.fe.t bila.e.a. ne.ropa.hology a.d s.ns.rimotor de.icits.on da. 30 *** s.udy found tha. rNurr1-V5 e.pre.1}ion but not tha. of the.gre.n fluore.1}e.t prote.n(the.ne.a.ive.control)re.uce.β-s.tos.e.olβ-D-glucos.de.induce. ***,a.bila.e.a. incre.0}0} in tyros.ne.hydroxyla.0}-pos.tive.ce.ls.a.d a.boriza.ion occurre. in the.s.bs.a.tia.nigra.a.d incre.0}0}d tyros.ne.hydroxyla.0}-pos.tive.ra.ifica.ions.in the.*** a.dition,tyros.ne.hydroxyla.0}-pos.tive.ce.ls.dis.la.e. le.1} s.ne.1}e.ce.ma.ke.β-ga.a.tos.da.0} a.d more.ne.ron-cytos.e.e.on ma.ke.βIII-tubulin a.d bra.n-de.ive. ne.rotrophic fa.tor.a.s.gnifica.t de.re.0}0} in a.tiva.e. microglia.pos.tive.to ionize. ca.cium-binding a.a.tor mole.ule.1)a.d ne.rotoxic a.0}rocyte.1}pos.tive.to glia. fibrilla.y a.idic prote.n a.d comple.e.t compone.t 3)a.d incre.0}0}d ne.rotrophic a.0}rocyte.1}pos.tive.to glia. fibrilla.y a.idic prote.n a.d s.00 ca.cium-binding prote.n a.0)a.s. occurre. in the.s.bs.a.tia.*** e.fe.ts.followe. the.bila.e.a. re.uction inα-s.nucle.n a.gre.a.e.1}in the.nigros.ria.a. s.s.e.,improving s.ns.rimotor *** re.1}lts.s.ow tha. unila.e.a. rNurr1-V5 tra.s.e.e.e.pre.1}ion in nigra. dopa.ine.gic ne.rons.mitiga.e.1}bila.e.a. ne.rode.e.e.a.ion(s.ne.1}e.ce.a.d los. of ne.ron-cytos.e.e.on a.d tyros.ne.hydroxyla.0}-pos.tive.ce.ls.,ne.roinfla.ma.ion(a.tiva.e. microglia.ne.rotoxic a.0}rocyte.1},α-s.nucle.n a.gre.a.ion,a.d s.ns.rimotor *** ne.rotrophic a.0}rocyte.1}a.d

关键词： a. a.0}rocyte. a. a.0}rocyte. ge.e.the.a.y microglia motor de.icits na.opa.ticle. ne.rode.e.e.a.ion ne.roinfla.ma.ion s.ne.0}e.ce α-s.nucle.n a.gre.a.e.

Comme.ta.y on "a.0}ocia.ion of da.ly s.tting time.a.d le.s.re.time.phys.ca. a.tivity with body fa. a.ong ***"

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Journa. of s.ort a.d He.0}th s.ie.ce 2024年第2期13卷 127-129页

作者： Ba.ba.a.e.a.ns.orth s.hool of e.e.cis. a.d He.2}th Shanghai University of SportShanghai 200438China

In the.r s.udy,a.0}ocia.ion of da.ly s.tting time.a.d le.s.re.time.phys.ca. a.tivity (LTPa. with body fa. a.ong ***,Lia. e. a..^(1) a.a.yze. da.a.from the.2011-2018 Na.iona. He.1}th a.d e.a.ina.ion s.rve. to e.a.ine.a.0}ocia.ions.be.we.n h/da. s.tting,me.ting (or not me.ting) the.*** a.tivity Guide.ine.0}of≥150 min/we.k of mode.a.e.a.d vigorous.inte.s.ty LTPa.a.d combina.ions.of s.tting time.a.d LTPa.on tota.a.d trunk pe.ce.t body fa. (BF%).

关键词： u.s. a.ult a.ong

Ground-ba.0}d a.d a.ditiona. s.ie.ce.s.pport for s.ILe

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e.0}th a.d Pla.e.a.y Phys.cs 2024年第1期8卷 275-298页

作者： J.a.Ca.te. M.Dunlop C.Fors.th K.Oks.vik e.Donovon a.Ka.a.a.h s.e.Mila. T.s.rgie.ko R.C.Fe.0} D.G.s.be.k M.Connors.T.Ye.ma. X.Ta. M.G.G.T.Ta.lor K.McWillia.s.J.Gje.loe. R.Ba.ne.2}D.D.Bille. G.Chis.a. a.Dimmock M.P.Fre.ma. D.-s.Ha. M.D.Ha.tinge. s.-Y.W.Hs.e. Z.-J.Hu M.K.Ja.e.2}L.Juus.la.K.Ka.ris.ie.e.a.Kronbe.g M.Le.2}e. J.Ma.ue. J.Ma.zka.I.McCre.0}Y.Miyos.i J.Ra. L.Re. F.s.ge.ne.2}e.s.a.s.ick K.s.e.ne.a.s.e.we. T.s.n M.-T.Wa.a.h B.Wa.s. C.Wa.g J.We.ga.d J.Wild J.Ya. J.Zha.g Q.-H.Zha.g Pla.e.a.y s.ie.ce.2}Group School of Physics and AstronomyUniversity of LeicesterUniversity RoadLeicesterLE17RHUK Ruthe.ford a.ple.on La.ora.ory s.a.e Science Technology Facilities CouncilOxfordshireUK s.hool of s.a.e.a.d e.vironme.t Beihang UniversityBeijing 100191China Ke. La.ora.ory of s.a.e.e.vironme.t Monitoring a.d Informa.ion Proce.2}ing Ministry of Industry and Information TechnologyBeijing 100017China De.a.tme.t of s.a.e.a.d Clima.e.Phys.cs UCLMullard Space Science LaboratoryHolmbury St.MaryDorkingSurreyRH56NTUK Birke.a.d Ce.tre.for s.a.e.s.ie.ce Department of Physics and Technology.University of BergenBergenNorway De.a.tme.t of Phys.cs.a.d a.0}ronomy University of Calgary2500 University DriveCalgaryAlbertaCanada T2N 1N4 Britis. a.ta.ctic s.rve. CambridgeUK s.e.is. Ins.itute.of s.a.e.Phys.cs KirunaSweden We.0} Highfie.d Ca.pus University of SouthamptonUniversity RoadSO171BJUK Godda.d s.a.e.Flight Ce.te. NASAGreenbeltMarylandUSA a.ha.a.0}a.unive.s.ty AthabascaCanada e.0}e. European Space AgencyNetherlands unive.s.ty of s.s.a.che.a. SaskatoonCanada The.Johns.Hopkins.unive.s.ty a.plie. Phys.cs.La.ora.ory LaurelMarylandUSA s.e.is. Ins.itude.of s.a.e.Phys.cs UppsalaSE 75121Sweden Tongji unive.s.ty Shanghai 200092China Ce.te. for s.a.e.Pla.0}a.Phys.cs Space Science Institute4765 Walnut Street Suite BBoulderColorado80301USA Pola. Re.1}a.ch Ins.itute.of China Shanghai 200136China Finnis. Me.e.rologica. Ins.itute.FMI) Finland De.a.tme.t of e.0}th a.d e.vironme.ta. s.ie.ce.4}Ge.phys.cs. Ludwig Maximilian University of Munich(LMU)MunichTheresienstr.41MunichD-80333Germany Ca.a.ia. s.a.e.a.e.cy MontrealCanada GFZ Ge.ma. Re.1}a.ch Ce.tre.for Ge.s.ie.ce. PotsdamGermany Na.oya.unive.s.ty Institute for Space Earth Environment ResearchCenter for Integrated Data ScienceNagoyaAichiJP 464-8601 Northumbria.unive.s.ty Newcastle upon TyneTyne and WearUK NE18ST Na.iona. s.a.e.s.ie.ce.Ce.te. Chinese Academy SciencesBeijing 100190China a.ctic Ge.phys.cs University Centre in Svalbard

The.joint e.rope.0} s.a.e.a.e.cy a.d Chine.1} a.a.e.y of s.ie.ce.1}s.la. wind Ma.ne.os.he.e.Ionos.he.e.Link e.plore.(s.ILe.mis.ion will e.plore.globa. dyna.ics.of the.ma.ne.os.he.e.unde. va.ying s.la. wind a.d inte.pla.e.a.y ma.ne.ic fie.d conditions.a.d s.multa.e.us.y monitor the.a.rora. re.1}ons. of the.Northe.n He.is.he.e.*** the.1} la.ge.s.a.e.re.1}ons.s.with me.ium a.d fine.s.a.e.me.0}0}re.e.ts.a. a.va.ie.y of ca.e.ce.1}by a.ditiona. ground-ba.0}d a.d s.a.e.ba.0}d ins.rume.ts.will e.a.le.a.much gre.0}e. s.ie.tific impa.t be.ond the.origina. goa.s.of the.s.ILe.***,we.de.1}ribe.curre.t community e.forts.to pre.a.e.for s.ILe.a.d the.be.e.its.a.d conte.t va.ious.e.pe.ime.ts.tha. ha.e.e.plicitly e.pre.1}e. s.pport for s.ILe.ca. offe..a.de.ica.e. group of inte.na.iona. s.ie.tis.s.re.re.1}nting ma.y diffe.e.t e.pe.ime.t type.1}a.d ge.gra.hica. loca.ions.the.Ground-ba.0}d a.d a.ditiona. s.ie.ce.Working Group,is.fa.ilita.ing the.1} *** include.cons.ructing a. online.s.ILe.Da.a.Fus.on Fa.ility,the.dis.us.ion of pa.ticula. or s.e.ia. mode.1}for e.pe.ime.ts.s.ch a.0}cohe.e.t a.d incohe.e.t s.a.te. ra.a.,a.d the.cons.de.a.ion of pa.ticula. obs.rving s.ra.e.ie.1}a.d s.a.e.ra.t *** a.ticipa.e.growing inte.e.1} a.d community e.ga.e.e.t with the.s.ILe.mis.ion,a.d we.we.come.nove. ide.0}0}a.d ins.ghts.from the.s.la.-te.re.1}ria. community.

关键词： ma.ne.os.he.e ionos.he.e ma.ne.os.he.e.ionos.he.e.coupling ground-ba.0}d e.pe.ime.ta.ion s.ILe conjunctions mis.ions

Bra.n dys.unctions.a.d ne.rotoxicity induce. by ps.chos.imula.ts.in e.pe.ime.ta. mode.s.a.d huma.s.a. ove.vie. of re.e.t findings

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Ne.ra. Re.e.e.a.ion Re.2}a.ch 2024年第9期19卷 1908-1918页

作者： Ma.ce.lo s.rra.Nicola.s.mola.a.e.ia.e.Polla.k Giulia.Cos.a De.a.tme.t of Biome.ica. s.ie.ce. Section of NeuroscienceUniversity of CagliariCagliariItaly De.a.tme.t of Biology University of Massachusetts-BostonBostonMAUSA

Pre.linica. a.d clinica. s.udie.3}indica.e.tha. ps.chos.imula.ts.in a.dition to ha.ing a.us. pote.tia.,ma. e.icit bra.n dys.unctions.a.d/or ne.rotoxic *** toxicity induce. by ps.chos.imula.ts.ma. pos. s.rious.he.0}th ris.s.s.nce.the.re.re.0}iona. us. of the.3} s.bs.a.ce.3}is.on the.ris. a.ong young pe.ple.a.d *** pre.3}nt re.ie. provide.3}a. ove.vie. of re.e.t re.3}a.ch,conducte. be.we.n 2018 a.d 2023,focus.ng on bra.n dys.unctions.a.d ne.rotoxic e.fe.ts.e.icite. in e.pe.ime.ta. mode.s.a.d huma.s.by a.phe.a.ine.coca.ne.me.ha.phe.a.ine.3,4-me.hyle.e.ioxyme.ha.phe.a.ine.me.hylphe.ida.e.ca.fe.ne.a.d *** e.ucida.ion of fa.tors.a.d me.ha.is.s.tha. unde.lie.ps.chos.imula.t-induce. bra.n dys.unction a.d ne.rotoxicity is.crucia. for unde.s.a.ding the.a.ute.a.d e.during noxious.bra.n e.fe.ts.tha. ma. occur in individua.s.who us. ps.chos.imula.ts.for re.re.0}iona. a.d/or the.a.e.tic purpos.s.

关键词： 3,4-me.hyle.e.ioxyme.ha.phe.a.ine a.phe.a.ine ca.fe.ne ce.l culture. coca.ne me.ha.phe.a.ine me.hylphe.ida.e ne.rotoxicity nicotine