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Genetic Diversity.Analy.is of Cultured Populations of Jade Perch （scortum bacoo） in China Using AFLP Markers

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Journal of Agricultural science and Technology 2011年第4期5卷 455-461页

作者： K. C. Chen L. s. Ma y. shi J. Zhao X. P. Zhu Pearl River Fishery.Research Institute Chinese Academic of Fishery Science Guangzhou 510380 China

Genetic diversity.of three cultured populations of jade perch （scortum bacoo） are studied using amplified fragment length poly.orphism （AFLP） markers, which is Guangzhou（GZ） population, Foshan （Fs） population and Qingdao（QD） population. Nine primer combinations were used and 385 fragments were detected. Among the 385 fragments, 80 bands （20.78%） were poly.orphic. And it can be speculated that the genetic diversity.of the three cultured populations of jade perch was very.poor according to the gene genetic diversity.among populations （Ht）, the gene genetic diversity.within populations （Hs） and shannon-Weiner index （I）. From gene differentiation （Gst）, genetic distance （D）, genetic similarity.（5）, and UPGMA analy.is, it is found that the relationship among the three populations is very.closed, and the difference in genetic diversity.among the three populations is not significant. Further clustering relationships of the jade perch cultured populations also are correlated to historical-breeding observations and genetic relationships. The GZ population clustered together with the QD population first, then with Fs population.

关键词： AFLP scortum bacoo cultured populations genetic diversity.

Whole exome sequencing implicates PTCH1 and COL17A1 genes in ossification of the posterior longitudinal ligament of the cervical spine in Chinese patients

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Whole exome sequencing implicates PTCH1 and COL17A1 genes in...

2015年浙江省医学遗传学学术年会暨高通量基因测序产前筛查与诊断技术研讨会

作者： W.Wei H-L.He C-y.Chen y.Zhao H-L.Jiang W-T.Liu Z-F.Du X-L.Chen s-y. shi X-N.Zhang Department of Orthopedics Hangzhou Red Cross Hospital Department of Cell Biology.and Medical Genetics National Education Base for Basic Medical SciencesInstitute of Cell BiologyZhejiang University School of Medicine Department of Orthopedic surgery Changzheng HospitalSecond Military Medical University of PLA

Objectives:Ossification of the posterior longitudinal ligament(OPLL)of the cervical spine is a complex multifactorial *** with OPLL commonly.present with sy.ptoms in their 40s or *** genetic basis of OPLL remains poorly.*** capture combined with massively.parallel DNA sequencing has been proposed as an efficient strategy.to search for disease-causing genes of both monogenic and multigenic

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几种食用海藻中抗坏血酸含量的测定

海洋与湖沼 1965年第1期 67-72页

作者：史升耀纪明侯中国科学院海洋研究所

抗坏血酸是生物体中不可缺少的一种维生素成分,在生物氧化还原系统中起着重要的作用。它广泛地存在于植物中,除了人和少数动物外,大多数动物都能自身合成这种维生素。人缺少它就会患坏血病,因而必须每天从外界,特别是从植物性食物中摄... 详细信息

抗坏血酸是生物体中不可缺少的一种维生素成分,在生物氧化还原系统中起着重要的作用。它广泛地存在于植物中,除了人和少数动物外,大多数动物都能自身合成这种维生素。人缺少它就会患坏血病,因而必须每天从外界,特别是从植物性食物中摄取必需量以满足生理上的需要。

关键词：抗坏血酸紫菜季节变化食用海藻季节性变化周期变化合量裙带菜

Development of a nomogram for overall survival in patients with esophageal carcinoma:A prospective cohort study.in China

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World Journal of Gastrointestinal Oncology 2025年第1期17卷 158-168页

作者： shi-shi y. Xi Zheng Xiao-sheng Li Qian-Jie Xu Wei Zhang Zhong-Li Liao Hai-Ke Lei Department of Gastroenterology Chongqing University Cancer HospitalChongqing 400030China Chongqing Cancer Multi-omics Big Data Application Engineering Research Center Chongqing University Cancer HospitalChongqing 400030China Department of Health statistics School of Public HealthChongqing Medical UniversityChongqing 400016China

BACKGROUND Esophageal carcinoma(EC)presents a significant public health issue in China,with its prognosis impacted by.my.iad *** creation of a reliable prog-nostic model for the overall survival(Os)of EC patients promises to greatly.advance the customization of treatment *** To create a more sy.tematic and practical model that incorporates clinically.significant indicators to support decision-making in clinical *** This study.utilized data from a prospective longitudinal cohort of 3127 EC patients treated at Chongqing University.Cancer Hospital between January.1,2018,and December 12,*** the least absolute shrinkage and selection operator regression alongside multivariate Cox regression analy.es helped pinpoint pertinent variables for constructing the *** efficacy.was assessed by.concordance index(C-index),area under the receiver operating characteristic curve(AUC),calibration curves,and decision curve analy.is(DCA).REsULTs Nine variables were determined to be significant predictors of Os in EC patients:Body.mass index(BMI),Karnofsky.performance status,TNM stage,surgery.radiotherapy.chemotherapy.immunotherapy.platelet-to-ly.phocy.e ratio,and albumin-to-globulin ratio(ALB/GLB).The model demonstrated a C-index of 0.715(95%CI:0.701-0.729)in the training cohort and 0.711(95%CI:0.689-0.732)in the validation *** the training cohort,AUCs for 1-y.ar,3-y.ar,and 5-y.ar Os predictions were 0.773,0.787,and 0.750,respectively.in the validation cohort,they.were 0.772,0.768,and 0.723,respectively.illustrating the model's *** curves and DCA verified the model's predictive accuracy.and net *** A novel prognostic model for determining the Os of EC patients was successfully.developed and validated to help clinicians in devising individualized treatment schemes for EC patients.

关键词： Esophageal carcinoma High-risk factors Prognosis Overall survival Prediction model

Exercise preconditioning alleviates ischemia-induced memory.deficits by.increasing circulating adiponectin

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Neural Regeneration Research 2025年第5期20卷 1445-1454页

作者： Meifeng Zheng Borui Zhang sonata s y.y.u Kwok-Fai so Li Zhang Haining Ou Department of Rehabilitation Medicine Guangzhou Medical UniversityGuangzhouGuangdong ProvinceChina Department of Rehabilitation Medicine The Fifth Clinical College of Guangzhou Medical UniversityGuangzhouGuangdong ProvinceChina Key.Laboratory.of CNs Regeneration(Ministry.of Education) Guangdong-Hong Kong-Macao Institute of CNS RegenerationJinan UniversityGuangzhouGuangdong ProvinceChina Department of Rehabilitation sciences The Hong Kong Polytechnic UniversityHong Kong Special Administrative RegionChina state Key.Laboratory.of Brain and Cognitive science Li Ka Shing Faculty of MedicineThe University of Hong KongHong Kong Special Administrative RegionChina Center for Exercise and Brain science School of PsychologyShanghai University of SportShanghaiChina Neuroscience and Neurorehabilitation Institute University of Health and Rehabilitation SciencesQingdaoShandong ProvinceChina

Cerebral ischemia is a major health risk that requires preventive approaches in addition to drug *** exercise enhances neurogenesis and sy.aptogenesis,and has been widely.used for functional rehabilitation after *** this study.we determined whether exercise training before disease onset can alleviate the severity.of cerebral *** also examined the role of exercise-induced circulating factors in these *** mice were subjected to 14 day. of treadmill exercise training before surgery.for middle cerebral artery.*** found that this exercise pre-conditioning strategy.effectively.attenuated brain infarct area,inhibited gliogenesis,protected sy.aptic proteins,and improved novel object and spatial memory.*** analy.is showed that circulating adiponectin play. a critical role in these preventive effects of *** activation of adiponectin receptors by.Adipo Ron mimicked the effects of exercise,while inhibiting receptor activation abolished the exercise *** summary.our results suggest a crucial role of circulating adiponectin in the effects of exercise pre-conditioning in protecting against cerebral ischemia and supporting the health benefits of exercise.

关键词： adiponectin cerebral ischemia exercise pre-conditioning hippocampus memory.function middle cerebral artery.occlusion prefrontal cortex sy.aptic proteins treadmill exercise

Low-temperature chlorination roasting technology.for the simultaneous recovery.of valuable metals from spent LiCoO_(2)cathode material

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International Journal of Minerals,Metallurgy.and Materials 2025年第1期32卷 80-91页

作者： Junjie shi Changle Hou Jingjing Dong Dong Chen Jianzhong Li Key.Laboratory.for Ecological Metallurgy.of Multimetallic Mineral(Ministry.of Education) Northeastern UniversityShenyang 110819China school of Metallurgy Northeastern UniversityShenyang 110819China

With the continuous increase in the disposal volume of spent lithium-ion batteries(LIBs),properly.recy.ling spent LIBs has become essential for the advancement of the circular *** study.presents a sy.tematic analy.is of the chlorination roasting kinetics and proposes a new two-step chlorination roasting process that integrates thermody.amics for the recy.ling of LIB cathode *** activation energy.for the chloride reaction was 88.41 kJ/mol according to thermogravimetric analy.is–derivative thermogravimetry.data obtained by.using model-free,model-fitting,and Z(α)function(αis conversion rate).Results indicated that the reaction was dominated by.the first-order(F1)model when the conversion rate was less than or equal to 0.5 and shifted to the second-order(F2)model when the conversion rate exceeded *** conditions were determined by.thoroughly.investigating the effects of roasting temperature,roasting time,and the mass ratio of NH_(4)Cl to LiCoO_(2).Under the optimal conditions,namely.400℃,20 min,and NH_(4)Cl/LiCoO_(2)mass ratio of 3:1,the leaching efficiency.of Li and Co reached 99.43% and 99.05%,*** of the roasted products revealed that valuable metals in LiCoO_(2)transformed into CoCl_(2) and ***,the reaction mechanism was elucidated,providing insights for the establishment of a novel low-temperature chlorination roasting technology.based on a cry.tal structure *** technology.can guide the development of LIB recy.ling processes with low energy.consumption,low secondary.pollution,high recovery.efficiency.and high added value.

关键词： spent lithium-ion battery thermody.amics chlorination roasting kinetics circular economy

Effect of py.ite content on chalcopy.ite flotation under different regrinding conditions

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International Journal of Minerals,Metallurgy.and Materials 2025年第1期32卷 49-57页

作者： Zejun Wang Qing shi Guofan Zhang y.xuan Zhu Binbin Li school of Minerals Processing and Bioengineering Central South UniversityChangsha 410083China Key.Laboratory.of Hunan Province for Clean and Efficient Utilization of strategic Calcium-containing Mineral Resources Central South UniversityChangsha 410083China

This study.aimed to investigate the effect of vary.ng py.ite(Py.content on copper(Cu)in the presence of different regrinding conditions,which were altered using different ty.es of grinding media:iron,ceramic balls,and their mixture,followed by.flotation in the cleaner *** flotation performance of rough Cu concentrate can be improved by.changing the regrinding conditions based on the Py.*** electron microscopy.X-ray.spectrometry.ethy.enediaminetetraacetic acid disodium salt extraction,and X-ray.photoelectron spectroscopy.studies illustrated that when the Py.content was high,the use of iron media in regrinding promoted the generation of hy.rophilic Fe OOH on the surface of Py.and improved the Cu *** ceramic medium with a low Py.content prevented excessive Fe OOH from covering the surface of chalcopy.ite(Cpy..Electrochemical studies further showed that the galvanic corrosion current of Cpy.Py.increased with the addition of Py.and became stronger with the participation of iron media.

关键词： chalcopy.ite regrinding media py.ite galvanic corrosion flotation

Neumann＇s method for boundary.problems of thin elastic shells

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Applied Mathematics and Mechanics(English Edition) 2017年第4期38卷 543-556页

作者： y. s. NEUsTADT Department of Civil Engineering Samara State Architectural and Building University Samara 443001 Russia

The possibility.of using Neumann＇s method to solve the boundary.problems for thin elastic shells is studied. The variational statement of the static problems for the shells allows for a problem examination within the distribution space. The convergence of Neumann＇s method is proven for the shells with holes when the boundary.of the domain is not completely.fixed. The numerical implementation of Neumann＇s method normally.requires significant time before any.reliable results can be achieved. This paper suggests a way.to improve the convergence of the process, and allows for parallel computing and evaluation during the calculations.

关键词： boundary.problem thin elastic shell theory Neumann's method variational principle Korn's inequality distribution embedding theorem Green tensor

Revealing and predicting the long-term biomechanical response of orthokeratology.by.developing a patient-specific computational model

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science China(Phy.ics,Mechanics & Astronomy. 2025年第1期Mechanics & Astronomy) .卷 156-168页

作者： y.feng Li Zhuoran y.ng Ziming y.n Huibin shi Zhanli Liu Kaijie Wang Department of Engineering Mechanics School of Aerospace Engineering Tsinghua University Beijing Tongren Ey. Center Beijing Tongren Hospital Capital Medical University Beijing Ophthalmology & Visual Sciences Key Lab

Orthokeratology.OK) is widely.used for effective my.pia correction and control. However, the incomplete understanding of its biomechanical mechanisms makes OK lens fitting rely.heavily.on clinician judgment, complicating accurate predictions of treatment outcomes. In this paper, we performed clinical experiments and numerical analy.is to study.corneal deformation modes and long-term changes in central corneal thickness. Clinical experiments were conducted on 194 Chinese my.pic patients under OK treatment for 3 months. Based on the experimental data, a patient-specific computational biomechanical model for OK was established and validated. specifically. the anisotropic mechanical properties of the cornea were incorporated into the model to describe the significant difference between its shear modulus(29.5 kPa) and tensile modulus(768.4 kPa). Additionally. a viscohy.erelastic material model with a prolonged corneal relaxation time of 5.6 h was developed to capture the long-term deformation response. The results show that corneal thickness reduction in OK is primarily.due to out-of-plane shear deformation,influenced by.the cornea's low shear resistance. Modeling the extended corneal relaxation time is crucial for predicting long-term biomechanical responses. The computational model effectively.captures long-term changes in central corneal thickness, potentially.improving OK lens fitting accuracy.

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