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Identification of telomere maintenance gene variations related to lung adenocarcinoma risk by genome-wide association and whole genome sequencing analyses

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Cancer Communications 2024年第2期44卷 287-293页

作者： Kouya Shiraishi Atsushi Takahashi Yukihide Momozawa Yataro Daigo Syuzo Kaneko Takahisa Kawaguchi Hideo Kunitoh Shingo Matsumoto Hidehito Horinouchi Akiteru Goto Takayuki Honda Kimihiro Shimizu Masahiro Torasawa Daisuke Takayanagi Motonobu Saito Akira Saito Yuichiro Ohe Shun-ichi Watanabe Koichi Goto Masahiro Tsuboi Katsuya Tsuchihara Sadaaki Takata Tomomi Aoi Atsushi Takano Masashi Kobayashi Yohei Miyagi Kazumi Tanaka Hiroyuki Suzuki Daichi Maeda Takumi Yamaura Maiko Matsuda Yoko Shimada Takaaki Mizuno Hiromi Sakamoto Teruhiko Yoshida Yasushi Goto Tatsuya Yoshida Taiki Yamaji Makoto Sonobe Shinichi Toyooka Kazue Yoneda Katsuhiro Masago Fumihiro Tanaka Megumi Hara Nobuo Fuse Satoshi S.Nishizuka Noriko Motoi Norie Sawada Yuichiro Nishida Kazuki Kumada Kenji Takeuchi Kozo Tanno Yasushi Yatabe Kuniko Sunami Tomoyuki Hishida Yasunari miyazaki Hidemi Ito Mitsuhiro Amemiya Hirohiko Totsuka Haruhiko Nakayama Tomoyuki Yokose Kazuyoshi Ishigaki Toshiteru Nagashima Yoichi Ohtaki Kazuhiro Imai Ken Takasawa Yoshihiro Minamiya Kazuma Kobayashi Kenichi Okubo Kenji Wakai Atsushi Shimizu Masayuki Yamamoto Motoki Iwasaki Koichi Matsuda Johji Inazawa Yuichi Shiraishi Hiroyoshi Nishikawa Yoshinori Murakami Michiaki Kubo Fumihiko Matsuda Yoichiro Kamatani Ryuji Hamamoto Keitaro Matsuo Takashi Kohno Division of Genome Biology National Cancer Center Research InstituteTokyoJapan Department of Clinical Genomics National Cancer Center Research InstituteTokyoJapan Laboratory for Statistical Analysis Center for Integrative Medical SciencesRIKENYokohamaJapan Department of Genomic Medicine Research InstituteNational Cerebral and Cardiovascular CenterOsakaJapan Laboratory for Genotyping Development Center for Integrative Medical SciencesRIKENYokohamaJapan Center for Antibody and Vaccine Therapy Research HospitalInstitute of Medical ScienceThe University of TokyoTokyoJapan Department of Medical Oncology and Cancer Center and Center for Advanced Medicine against CancerShiga University of Medical ScienceOtsuJapan Division of Medical AI Research and Development National Cancer Center Research InstituteTokyoJapan Center for Genomic Medicine Graduate School of MedicineKyoto UniversityKyotoJapan Department of Medical Oncology Japanese Red Cross Medical CenterTokyoJapan Department of Thoracic Oncology National Cancer Center Hospital EastJapan Department of Thoracic Oncology National Cancer Center HospitalTokyoJapan Department of Cellular and Organ Pathology Graduate School of MedicineAkita UniversityAkitaJapan Department of Respiratory Medicine Tokyo Medical and Dental UniversityBunkyo-kuTokyoJapan Division of General Thoracic Surgery Department of SurgeryShinshu University School of MedicineMatsumotoNaganoJapan Department of General Surgical Science Division of General Thoracic SurgeryGunma University Graduate School of MedicineIntegrative Center of General SurgeryGunma University HospitalGunmaJapan Department of Gastrointestinal Tract Surgery Fukushima Medical University School of MedicineFukushimaJapan StaGen Co. LtdTokyoJapan Division of Thoracic Surgery National Cancer Center HospitalTokyoJapan Department of Thoracic Surgery National Cancer Center Hospital EastChibaJapan Division of Translational Informatics Exploratory Oncology Research and Clinical Trial Center(EPOC

Dear editor,Lung carcinoma is responsible for the highest fatal-ity rate among cancer-related deaths globally,with lung adenocarcinoma(LADC)emerging as the prevailing sub-type.

关键词： adenocarcinoma lung Lung

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Characteristics of shape memory and superelasticity for TiNi thin films

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中国有色金属学会会刊：英文版 2000年第3期10卷 375-377页

作者： HE Zhi rong(贺志荣) 1, S.miyazaki 2 1. Department of Mechanical Engineering, Shaanxi Institute of Technology, Hanzhong 723003, P.R.China 2. University of Tsukuba, Japan 陕西工学院陕西汉中 University of Tsukuba 日本

TiNi shape memory alloy thin films were deposited by using a RF magnetron sputtering apparatus. The transformation and shape memory characteristics of the thin films have been investigated by using DSC and tensile tes... 详细信息

关键词： TiNi alloy shape memory effect superelasticity thin film

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Comparison of self-report and objective measures of male sexual dysfunction in a Japanese primary care setting:a cross-sectional,self-administered mixed methods survey

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Family Medicine and Community Health 2021年第1期9卷 18-27页

作者： Yuki Takeuchi ryohei Otsuka Hajime Kojima Michael D Fetters Teine Family Medicine Clinic Teine Keijinkai HospitalSapporoHokkaidoJapan Mixed Methods Program Department of Family MedicineUniversity of MichiganAnn ArborMichiganUSA

Objectives Erectile dysfunction(ED)is a common problem among middle-aged males and men often do not talk about sexual problems with their primary care physicians(PCPs).We hypothesised that many Japanese men who meet the criteria for ED would not recognise their condition based on responses to an internationally validated *** secondary aims were to examine potential barriers to seeking treatment for ED by their *** sought to elucidate their perspectives about male sexual dysfunction *** merging of the quantitative and qualitative findings,we sought an enhanced understanding of the factors affecting sexual dysfunction *** A cross-sectional,self-administered mixed methods survey was distributed at a suburban family medicine clinic in Sapporo,*** participants were 40 to 69-year old men who came for routine scheduled visits from 5 November to 21 December *** the office visit,participants completed a confidential 11-item survey addressing sexual dysfunction including the 5-item version of the International Index of Erectile Function scale and open-ended *** Teine Family Medicine Clinic,a suburban family medicine clinic in Sapporo,*** We enroled 66 male patients aged 40-69 years who presented for routine outpatient care in the Teine Family Medicine *** Of surveyed participants,39%(26/66)reported having sexual dysfunction,but 92%(61/66)met ED *** respondents,48%(16/33)had desire for treatment,but only one man had discussed sexual dysfunction with his *** the 12 desiring treatment from PCPs,the main barriers to discussing were shame(n=7)and lack of awareness that PCPs can treat ED(n=5).These men’s perspectives about sexual dysfunction included viewing sexual dysfunction as normal ageing,attributing sexual dysfunction to decreased libido,considering sexual activity for a healthy life,having good rapport with PCPs,having incomplete knowledge about treatment and l

关键词： routine sectional measures

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Hydrogenation and Anisotropic Expansions in R_3Fe_(29-x)T_x (R=Y, Ce, Nd, Sm, Gd, Tb and Dy; T=V and Cr)

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Journal of Materials Science & Technology 1999年第1期15卷 5-9页

作者： Xiufeng HAM and Lanyng LIN(Materials Science Center, Institute of Semiconductors, Chinese Academy of Sciences, Beijing 100083, China)T.miyazaki(Dept. of Applied Physics, Faculty of Engineering, Tohoku University, Sendai 980-77, Japan)Fuming YANG(Institute Materials Science Center Institute of Semiconductors Chinese Academy of Sciences Beijing 100083 China Dept. of Applied Physics Faculty of Engineering Tohoku University Sendai 980-77 Japan Institute of Physics Chinese Academy of Sciences Beijing 100080 China Materials Department Zhejiang University Hangzhou 310027 China

A systematic study of the phase formation, structure and magnetic properties of the R3Fe29-xTxcompounds (R=Y, Ce, Nd, Sm, Gd, Tb, and Dy; T=V and Cr) has been performed uponhydrogenation. The lattice constants and the unit cell volume of R3Fe29-xTxHy decrease withincreasing R atomic number from Nd to Dy, except for Ce, reflecting the lanthanide *** anisotropic expansions mainly along the a- and b-axis rather than along the c-axis areobserved for all of the compounds upon hydrogenation. Hydrogenation leads to an increase inthe Curie temperature and a corresponding increase in the saturation magnetization at roomtemperature for each compound. First order magnetization processes (FOMP) occur in theexternal magnetic fields for Nd3Fe24.5Cr4.5H5.0, Tb3Fe27.0Cr2.0H2.8, and Gd3Fe28.0Cr1.0H4.2compounds

关键词： Hydrogenation and Anisotropic Expansions in R3Fe x)T_x R=Y Ce Sm Gd Nd

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A Variable Magnetic Flux Motor Suitable for Vehicle Applications

A Variable Magnetic Flux Motor Suitable for Vehicle Applicat...

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The 8th International PCIM China Conference

作者： Taizo miyazaki Shoichi Kawamata Noriaki Hino Houngjoong Kim Hitachi Ltd.

Permanent magnet motors are widely used in hybrid electric vehicles（HEVs） and electric vehicles（EVs） because they have high efficiency and small ***,the electric current for weakening the magnetic field control has to be increased because the induced electromotive force is increased in proportion to the revolution ***,the motor efficiency decreases at highrevolution *** this study,we developed a variable magnetic flux motor（VFM）,which has a control method for mechanically weakening a magnetic field to improve the motor efficiency at highrevolution *** to a conventional motor,the variable magnetic flux motor has a wider driving ***,its high-efficiency region expands to the high-revolution speed region.

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Mechanism of Pb Removal from Brass Scrap by Compound Separation Using Ca and NaF

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International Journal of Nonferrous Metallurgy 2018年第1期7卷 1-7页

作者： Hidekazu Sueyoshi Kousaku Yamada Masashi miyazaki Takuya Okada Nobuyuki Ashie Yoshiharu Kousaka Graduate School of Science and Engineering Kagoshima University Kagoshima Japan Kyushu Tabuchi Co. Ltd. Kirishima Japan San-Etsu Metals Co. Ltd. Tonami Japan

The Mechanism of Pb removal from brass scrap by compound separation using Ca and NaF addition was investigated. Because large Ca-Pb compound particles formed by Ca addition rise to the surface of the molten brass, they can be skimmed off from the molten brass. However, fine Ca-Pb compound particles remain in the molten brass because of low buoyancy. By subsequent NaF addition, the reaction between Ca-Pb compound and NaF takes place at their contact regions, resulting in the formation of solid CaF2, liquid Pb and Na gas. Pb is mainly present at the Ca-Pb compound-CaF2 interface. CaF2 acts as a binder for aggregation of fine Ca-Pb compound particles, resulting in the formation of light and large composite compounds, which rise to the surface of the molten brass. A high Pb removal rate is achieved by skimming off.

关键词： Lead Removal Brass Scrap Calcium Sodium Fluoride Compound Separation

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中国城市及城市群技术效率差异研究

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经济经纬 2013年第3期30卷 14-19页

作者：宣超中村良平中国人民大学国际学院江苏苏州215123 日本冈山大学

笔者通过随机前沿分析方法,测算中国不同地理范围的城市技术效率值并对其影响因素做出分析。研究发现,大规模生产资料的投入仍然是我国城市经济增长的主要决定因素;中国城市的生产效率并未出现逐年改进;东部城市群的技术效率一定程度上... 详细信息

笔者通过随机前沿分析方法,测算中国不同地理范围的城市技术效率值并对其影响因素做出分析。研究发现,大规模生产资料的投入仍然是我国城市经济增长的主要决定因素;中国城市的生产效率并未出现逐年改进;东部城市群的技术效率一定程度上优于中西部,单个城市的技术效率差异更加明显,现阶段的资源型小城市技术效率优于大中型城市;外资能够与城市技术效率改进形成良性互动,国内资本则反之。

关键词：城市技术效率随机前沿分析地区产出

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无形资产创造有形价值(上)

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新理财（公司理财） 2018年第10期 66-67页

作者： ryohei Yanagi Nina Michels-Kim 卫材药业有限公司 IMA东京分会的董事会 IMA

通过区分非财务指标和财务价值的所谓二分法，以及实证研究来表明无形资产和价值之间的清晰链接，进一步强调无形资产的重要性。Gary Cokins和Nick Shepherd在美国管理会计师协会（IMA）出版的《战略财务》杂志上曾发表“无形资产的力... 详细信息

通过区分非财务指标和财务价值的所谓二分法，以及实证研究来表明无形资产和价值之间的清晰链接，进一步强调无形资产的重要性。Gary Cokins和Nick Shepherd在美国管理会计师协会（IMA）出版的《战略财务》杂志上曾发表“无形资产的力量”，呼吁管理会计师们理解无形资产及其与价值创造的关系。

关键词：无形资产有形价值管理会计师协会财务价值非财务指标实证研究 Gary 二分法

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IC models for the simulation of the emission radiated from PCB

IC models for the simulation of the emission radiated from P...

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1997 International Symposium on Electromagnetic Compatibility

作者： Chiharu miyazaki Naoto Oka Takeshi Uchida Shuichi Nitta Information Technology R&D Center Mitsubishi Electric Corporation 5-1-1 OfunaKamakura.Kanagawa 247 Japan Faculty of Technology Tokyo University of Agriculture and Technology 2-24-16 Naka-cho.Koganei.Tokyo 184 Japan

＜正＞The authors are developing the technology that can simulate normal-mode emission radiated from printed circuit *** describe the driver and the receiver IC models which are needed to simulate radiated *** have derived the driver and the receiver IC *** validity of these models was confirmed by comparing measured data with the results of the simulation.

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超导磁悬浮列车推进线圈局部放电的绝缘诊断

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国外铁道机车与动车 2021年第6期 27-32页

作者： [日]ryohei IKEDA 刘志荣(译) 于伟业(校) 不详

磁悬浮列车需要大量的地面线圈,这些地面线圈安装在长期暴露的野外。因此,要对运用中的地面线圈进行维护,效能是至关重要的。磁悬浮列车运行时,将高电压施加到推进线圈。为检测预报推进线圈绝缘故障的局部放电,而设计了绝缘诊断方法[1-2... 详细信息

磁悬浮列车需要大量的地面线圈,这些地面线圈安装在长期暴露的野外。因此,要对运用中的地面线圈进行维护,效能是至关重要的。磁悬浮列车运行时,将高电压施加到推进线圈。为检测预报推进线圈绝缘故障的局部放电,而设计了绝缘诊断方法[1-2]。文章介绍了评定绝缘性能用的局部放电试样及对局部放电中电磁波传播的检查。

关键词：超导磁悬浮推进线圈绝缘诊断局部放电

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