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无形资产创造有形价值(下)

新理财（公司理财） 2018年第11期 63-64页

作者： ryohei yanagi Nina Michels-Kim 卫材药业有限公司 IMA东京分会 IMA

在上期文章中,我们为大家介绍了区分非财务指标和财务价值的二分法,并通过实证研究来表明无形资产和价值之间的清晰链接,进一步强调了无形资产的重要性。同时,我们也详细阐述了ROEESG模型的基本原理,为了进一步了解在实践中如何应用此模... 详细信息

在上期文章中,我们为大家介绍了区分非财务指标和财务价值的二分法,并通过实证研究来表明无形资产和价值之间的清晰链接,进一步强调了无形资产的重要性。同时,我们也详细阐述了ROEESG模型的基本原理,为了进一步了解在实践中如何应用此模型,卫材药业的CFO-Ryo yanagi将以日本卫材药业为例,做进一步的分析,并由为广大财务专业人士分享其实践经验。

关键词：无形资产有形价值财务价值实践经验非财务指标实证研究专业人士二分法

Nicotiana benthamiana XYLEM CYSTEINE PROTEASE genes facilitate tracheary element formation in interfamily grafting

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Horticulture Research 2023年第6期10卷 70-81页

作者： Chaokun Huang Ken-ichi Kurotani Ryo Tabata Nobutaka Mitsuda ryohei Sugita Keitaro Tanoi Michitaka Notaguchi Graduate School of Bioagricultural Sciences Nagoya UniversityFuro-choChikusa-kuNagoya 464-8601Japan Bioscience and Biotechnology Center Nagoya UniversityFuro-choChikusa-kuNagoya 464-8601Japan Bioproduction Research Institute National Institute of Advanced Industrial Science and Technology(AIST)TsukubaIbaraki 305-8566Japan Isotope Facility for Agricultural Education and Research Graduate School of Agricultural and Life SciencesThe University of TokyoYayoiBunkyo-kuTokyo 113-8657Japan Radioisotope Research Center Nagoya UniversityFuro-choChikusa-kuNagoya 464-8602Japan Institute of Transformative Bio-Molecules Nagoya UniversityFuro-choChikusa-kuNagoya 464-8601Japan

Grafting is a plant propagation technique widely used in agriculture.A recent discovery of the capability of interfamily grafting in Nicotiana has expanded the potential combinations of *** this study,we showed that xylem connection is essential for the achievement of interfamily grafting and investigated the molecular basis of xylem formation at the graft *** and gene network analyses revealed gene modules for tracheary element(TE)formation during grafting that include genes associated with xylem cell differentiation and immune *** reliability of the drawn network was validated by examining the role of the Nicotiana benthamiana XYLEM CYSTEINE PROTEASE(NbXCP)genes in TE formation during interfamily *** activities of NbXCP1 and NbXCP2 genes were found in differentiating TE cells in the stem and callus tissues at the graft *** of a Nbxcp1;Nbxcp2 loss-of-function mutant indicated that NbXCPs control the timing of de novo TE formation at the graft ***,grafts of the NbXCP1 overexpressor increased the scion growth rate as well as the fruit ***,we identified gene modules for TE formation at the graft boundary and demonstrated potential ways to enhance Nicotiana interfamily grafting.

关键词： grafting element graft

Effect of rubrene:P3HT bilayer on photovoltaic performance of perovskite solar cells with electrodeposited ZnO nanorods

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Journal of Energy Chemistry 2018年第2期27卷 455-462页

作者： Christian Mark Pelicano Hisao yanagi Graduate School of Materials Science Nara Institute of Science and Technology

Improved photovoltaic performance of perovskite solar cells is demonstrated through the synergistic effect of electrodeposited ZnO nanorods and rubrene：P3HT bilayer as electron and hole-transporting layers,respectively. Highly crystalline ZnO nanorods were obtained by electrochemical deposition in a chloride medium. Additionally, rubrene interlayer was able to passivate or cover the grain boundaries of perovskite film effectively that led to reduced leakage current. A perovskite solar cell optimized with ZnO nanorods and rubrene：P3HT bilayer achieved a maximum efficiency of 4.9% showing reduced hysteresis behavior compared with the device having P3HT as the only hole-transporting layer. The application of longer nanorods led to better perovskite infiltration and shorter charge carrier path length. These results highlight the potential of electrodeposited ZnO nanorods and rubrene：P3HT bilayer as charge selective layers for efficient perovskite solar cells.

关键词： Rubrene:P3HT bilayer Electrodeposited ZnO nanorods Perovskite solar cells

Risk factors for small intestinal adenocarcinomas that are common in the proximal small intestine

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World Journal of Gastroenterology 2022年第39期28卷 5658-5665页

作者： Shunji Fujimori ryohei Hamakubo Aitoshi Hoshimoto Takayoshi Nishimoto Jun Omori Naohiko Akimoto Shu Tanaka Atsushi Tatsuguchi Katsuhiko Iwakiri Department of Gastroenterology Chiba Hokusoh HospitalNippon Medical SchoolChiba 270-1694Japan Department of Gastroenterology Nippon Medical SchoolGraduate School of MedicineTokyo 113-8603Japan Department of Gastroenterology Tama-Nagayama HospitalNippon Medical SchoolTokyo 206-0025Japan

The frequency of primary small intestinal adenocarcinoma is increasing but is still *** frequency is approximately 3%of that of colorectal *** that the small intestine occupies 90%of the surface area of the gastrointestinal tract,small intestinal adenocarcinoma is very *** main site of small intestinal adenocarcinoma is the proximal small *** on this characteristic,dietary animal proteins/lipids and bile concentrations are implicated and reported to be involved in *** most nutrients are absorbed in the proximal small intestine,the effect of absorbable intestinal content is a suitable explanation for why small intestinal adenocarcinoma is more common in the proximal small *** proportion of aerobic bacteria is high in the proximal small intestine,but the absolute number of bacteria is *** addition,the length and density of villi are greater in the proximal small ***,the involvement of villi is considered to be low because the number of small intestinal adenocarcinomas is much smaller than that of colorectal *** the other hand,the reason for the low incidence of small intestinal adenocarcinoma in the distal small intestine may be that immune organs reside *** and disease factors increase the likelihood of small intestinal *** carcinogenesis experiments in which the positions of the small and large intestines were exchanged,tumors still occurred in the large intestinal mucosa more *** other words,the influence of the intestinal contents is small,and there is a large difference in epithelial properties between the small intestine and the large *** conclusion,small intestinal adenocarcinoma is rare compared to large intestinal adenocarcinoma due to the nature of the *** is reasonable to assume that diet is a trigger for small intestinal adenocarcinoma.

关键词： Small intestine Large intestine Adenocarcinoma Risk factor Carcinogenesis

Datacenter optics:requirements,technologies,and trends(Invited Paper)

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Chinese Optics Letters 2017年第5期15卷 87-90页

作者： Xiang Zhou Hong Liu ryohei Urata Platforms Google Inc. Mountain View CA 94043 USA

We review over a decade of technology evolution and advancement of intra-datacenter optical interconnect, mainly driven by the explosive bandwidth growth of web and cloud-based services. Emerging trends and tech-nolog... 详细信息

关键词： over will VCSEL Invited Paper Datacenter optics:requirements,technologies,and trends link BW

A novel use of TiO_2 fiber for photocatalytic ozonation of 2,4-dichlorophenoxyacetic acid in aqueous solution

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Journal of Environmental Sciences 2008年第9期20卷 1138-1145页

作者： GIRI Rabindra Raj OZAKI Hiroaki TAKANAMI ryohei TANIGUCHI Shogo New Industrial R & D Center Osaka Sangyo University Department of Civil Engineering Osaka Sangyo University

More efficient oxidation methods are needed to degrade especially newly emerging recalcitrant organic contaminants at low concentrations in the water environment. Reduced photonic efficiency of immobilized TiO2 is a major challenge in TiO2-assisted advanced oxidation processes (AOP). Mineralization of 2,4-dichllorophenoxyacetic acid (2,4-D) in low aqueous solution by O3/UV/TiO2 using the world’s first high-strength TiO2 fiber was investigated and compared with O3, UV/TiO2, and O3/TiO2 in laboratory batch ex...

关键词： dechlorination degradation intermediates radicals TiO2 total organic carbon (TOC)

Clinical significance of programmed cell death-ligand expression in small bowel adenocarcinoma is determined by the tumor microenvironment

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World Journal of Gastroenterology 2023年第40期29卷 5566-5581页

作者： Aitoshi Hoshimoto Atsushi Tatsuguchi ryohei Hamakubo Takayoshi Nishimoto Jun Omori Naohiko Akimoto Shu Tanaka Shunji Fujimori Tsutomu Hatori Akira Shimizu Katsuhiko Iwakiri Department of Gastroenterology Nippon Medical SchoolTokyo 113-8603Japan Department of Analytic Human Pathology Nippon Medical SchoolTokyo 113-8603Japan Department of Pathology Nippon Medical SchoolChiba Hokusoh HospitalChiba 270-1694Japan

BACKGROUND Comprehensive genomic analysis has shown that small bowel adenocarcinoma(SBA)has different genomic profiles from gastric and colorectal ***,it is essential to establish chemotherapeutic regimens based on SBA *** expression of programmed cell death-ligand 1(PD-L1)and programmed cell death-ligand 2(PD-L2)in SBA is not fully ***-PD-L1/PD-1 therapy uses tumor-infiltrating lymphocytes(TILs);therefore,the status of TILs in the tumor microenvironment(TME)may influence their *** ratio of FoxP3+to CD8+T cells has been reported to be useful in predicting the prognosis of digestive system *** To investigate the clinicopathological significance of PD-L1/2 expression according to the status of TILs in SBA *** We performed immunohistochemical analysis for PD-L1,PD-L2,CD8,FoxP3,and DNA mismatch repair(MMR)proteins using formalin-fixed,paraffin-embedded tissues from 50 patients diagnosed with primary *** immunoreactivities of PD-L1 and PD-L2 were determined separately in tumor cells and tumor-infiltrating immune cells throughout the tumor center and invasive margins,and finally evaluated using the combined positive score(CPS).We assessed CD8+and FoxP3+T cells in the intratumoral and tumor-surrounding ***,we calculated and summed the ratio of FoxP3 to CD8+T cell ***-related cell densities were graded as low or *** results were compared with clinicopathological factors and patient *** distribution of cancer-specific survival(CSS)was estimated using the Kaplan–Meier method,and the log-rank test was used to test for significant differences in CSS.A Cox proportional hazard model was also used to assess the effect of tumor variables on *** PD-L1 expression was positive in 34%in tumor cells(T-PD-L1)and 54%in tumor-infiltrating immune cells(I-PDL1)of the cases examined.T-PD-L2 was positive in 34%and I-PD-L2 was positive in 42%of the ***-L1

关键词： Small bowel adenocarcinoma Programmed cell death-ligand 1 Programmed cell death-ligand 2 Tumor microenvironment Tumor-infiltrating lymphocytes Regulatory T-cells

Thoracic surgery in dogs and cats

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畜牧与兽医 2012年第S2期44卷 20-24页

作者： ryohei Nishimura Veterinary Medical Center The University of Tokyo

1 Surgical Anatomy The ribs,sternum,and vertebral column form the thoracic *** intercostal space generally is two to three times as wide as the adjacent *** supply to the thoracic wall is provided by the intercostal arteries,which lie caudal to the adjacent rib in conjunction with a satellite vein and *** muscles of the thorax not only serve a structural function but also are important in respiration.

关键词： thoracic vertebral caudal respiration thorax arteries lymphatic skeleton incision conjunction

Sufficiently Elevated Core Body Temperature May Be Necessary to Maintain Cerebral Blood Flow Response throughout the Morning

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Neuroscience & Medicine 2022年第2期13卷 70-90页

作者： ryohei Tanaka-Kanegae*# Shingo Miyamoto Masao Sakurai Koichiro Hamada Saga Nutraceuticals Research Institute Otsuka Pharmaceutical Co. Ltd. Kanzaki Japan

In comparison to a carbohydrate-rich breakfast, a nutritionally balanced breakfast reportedly leads to a higher core body temperature because of diet-induced thermogenesis (DIT) and also results in higher task performance. This study aimed to examine the relationships among the core body temperature, blood glucose level, cerebral blood flow, and cognitive performance when the core body temperature is raised to a similar extent as in DIT in the morning. This crossover study included 18 male participants who performed four sets of cognitive tests in the morning with four different foot baths and glucose intake conditions. In elevated body temperature (EBT) conditions, the core body temperature was increased by a foot bath at 42˚C or 39˚C, while in low body temperature (LBT) conditions, it was maintained at 35˚C by a foot bath;the participants received no glucose or two intakes of 20-g glucose for each thermal condition. In addition to the core body temperature measurement, the cerebral blood flow in the dorsolateral prefrontal cortex (DLPFC) was measured using near-infrared spectroscopy. Three blood collections were performed to measure the changes in blood glucose levels. The results revealed that in the EBT conditions, the core body temperature remained 0.3˚C - 0.5˚C higher than that at wake-up time, while the glucose intake conditions increased blood glucose levels which remained higher than those during fasting. No significant between-treatment difference was observed in the results of cognitive tests. However, the blood flow in the DLPFC increased during the second test period in the EBT/glucose and LBT/glucose conditions, whereas during the fourth test period, it increased solely in the EBT/glucose condition. Thus, in addition to the blood glucose level, an elevated core body temperature within the physiological range may be needed for long-term maintenance of the cerebral blood flow response.

关键词： Elevated Core Body Temperature Cerebral Blood Flow Dorsolateral Prefrontal Cortex Near-Infrared Spectroscopy Cognitive Function Morning Breakfast Foot Bath