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Deciphering the regulatory code of histone modifications in plants

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Journal of Genetics and Genomics 2022年第11期49卷 1064-1067页

作者： Zhaohong Li Dongwei Li Ye Li Xiaoping Guo ruolin yang State Key Laboratory of Crop Stress Biology for Arid Areas College of Life SciencesInstitute of Future AgricultureNorthwest Agriculture&Forestry UniversityYanglingShaanxi 712100China

Eukaryotic genomes are compacted into histone-wrapped chromatin,which provides an opportunity to fine-tune the gene expression by dynamically impeding or reinforcing the accessibility of the genome to the transcription factors(TFs)and *** modification of histones is one of the various mechanisms to regulate DNA exposure by altering the physical properties of nucleosomes(Klemm et al.,2019).In plants,histone modifications play a critical role in establishing the cell identity and responding to environmental cues,including responses to temperature,alterations of flowering time(Liu et al.,2010;He et al.,2021).

关键词： cues establishing nucleosome

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医用有机化学课程中的案例教学

大学化学 2024年第1期39卷 69-72页

作者：刘坚华林琦姚莉韵杨秀岩杨若林上海交通大学基础医学院上海200025

“医用有机化学”是医学院各专业一年级学生的必修课,该课程难度较高,核心内容与临床实践相关性较低,容易使学生产生畏难情绪。我们在教学中通过引入真实临床案例,使学生认识到有机化学知识与临床的相关性,进而激发医学生们对课程学习... 详细信息

“医用有机化学”是医学院各专业一年级学生的必修课,该课程难度较高,核心内容与临床实践相关性较低,容易使学生产生畏难情绪。我们在教学中通过引入真实临床案例,使学生认识到有机化学知识与临床的相关性,进而激发医学生们对课程学习的热情。

关键词：医用有机化学案例教学临床实践

Micro/nanoelectrode-based electrochemical methodology for single cell and organelle analysis

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Nano Research 2024年第1期17卷 196-206页

作者： Chuchu Xu De yang Yuchan Wang ruolin Liu Fan Wang Zhongqun Tian Keke Hu Department of Chemistry College of Chemistry&Chemical EngineeringXiamen UniversityXiamen 361005China

Cells are the basic unit of *** analysis of single cells/organelles is essential for uncovering the molecular mechanisms of physiological and pathological processes that are difficult to elucidate on a larger *** paper provides an overview of the commonly used fabrication methods for micro/nanoelectrodes applied in the investigations of single cells/organelles as well as the corresponding electrochemical measurements over the last four years including extracellular measurement,combination of extra and intracellular measurement,intracellular reactive oxygen species and reactive nitrogen species(ROS/RNS)measurement,and isolated organelles measurement.

关键词： single cell/organelle micro/nanoelectrode electrochemical measurement chemical transmitters

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比较教学法在仪器分析实验教学中的应用

大学化学 2024年第3期39卷 266-273页

作者：谢一凡姚莉韵杨若林蔡玉兴金玉杰李宁上海交通大学医学院基础医学实验教学中心上海200025 上海交通大学医学院药物化学与生物信息学中心上海200025

仪器分析实验是医学预防及医学检验等专业的重要实验课程之一。为提升本科生的创新实践能力,设计了分别利用高效液相色谱仪(HPLC)和超高效合相色谱仪(UPC2)测定复方阿司匹林片中乙酰水杨酸和咖啡因含量的实验,并将思政元素有机地融入其... 详细信息

仪器分析实验是医学预防及医学检验等专业的重要实验课程之一。为提升本科生的创新实践能力,设计了分别利用高效液相色谱仪(HPLC)和超高效合相色谱仪(UPC2)测定复方阿司匹林片中乙酰水杨酸和咖啡因含量的实验,并将思政元素有机地融入其中。教学实践表明,通过对不同仪器原理、功能特点的比较学习,可以激发学生的实验兴趣和探索精神,增强学生解决问题的能力,进而提升学生的科学素养。

关键词：仪器分析实验乙酰水杨酸咖啡因比较教学法

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经皮耳甲迷走神经刺激治疗慢性意识障碍临床观察

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中国实用神经疾病杂志 2024年第5期27卷 552-556页

作者：雷彪王晓峰杨若琳于蓬勃李加龙邵威乔育陕西中医药大学陕西咸阳712046 宝鸡市中医医院陕西宝鸡721001 宝鸡第三医院陕西宝鸡721004

目的观察经皮耳甲迷走神经刺激(taVNS)治疗慢性意识障碍(pDoC)的临床效果。方法选取宝鸡第三医院2020-06—2022-12收治的68例pDoC患者,随机分成对照组与治疗组各34例。对照组接受常规促醒治疗,治疗组在对照组的基础上接受taVNS治疗,2... 详细信息

目的观察经皮耳甲迷走神经刺激(taVNS)治疗慢性意识障碍(pDoC)的临床效果。方法选取宝鸡第三医院2020-06—2022-12收治的68例pDoC患者,随机分成对照组与治疗组各34例。对照组接受常规促醒治疗,治疗组在对照组的基础上接受taVNS治疗,2组患者均治疗4周。对比2组患者格拉斯哥昏迷量表(GCS)评分、昏迷恢复量表(CRS-R)评分、全身无反应性量表(FOUR)评分、安全性及临床疗效。结果治疗后,2组患者的GCS单项评分(睁眼、言语和运动)及总分、CRS-R单项评分(听觉、视觉、运动、言语、交流和唤醒)及总分和FOUR单项评分(眼部、运动、脑干和呼吸)及总分均升高(均P0.05)。2组患者均未发生不良事件。治疗组总有效率(79.41%)显著高于对照组(61.76%)(P<0.05)。结论 taVNS治疗pDoC有一定的疗效,可改善患者意识障碍程度,且安全可靠。

关键词：经皮耳甲迷走神经刺激慢性意识障碍重型颅脑损伤

The First Verification Test of Space-Ground Collaborative Intelligence via Cloud-Native Satellites

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China Communications 2024年第4期21卷 208-217页

作者： Wang Shangguang Zhang Qiyang Xing ruolin Qi Fei Xu Mengwei State Key Laboratory of Networking and Switching Beijing University of Posts and TelecommunicationsBeijing 100876China Star Network and Intelligent Computing Laboratory Beiyou Shenzhen InstituteShenzhen 518000China Huawei Technologies Co. LtdShenzhen 518129China

Recent advancements in satellite technologies and the declining cost of access to space have led to the emergence of large satellite constellations in Low Earth Orbit(LEO).However,these constellations often rely on bent-pipe architecture,resulting in high communication *** onboard inference architectures suffer from limitations in terms of low accuracy and inflexibility in the deployment and management of in-orbit *** address these challenges,we propose a cloud-native-based satellite design specifically tailored for Earth Observation tasks,enabling diverse computing *** this work,we present a case study of a satellite-ground collaborative inference system deployed in the Tiansuan constellation,demonstrating a remarkable 50%accuracy improvement and a substantial 90%data *** work sheds light on in-orbit energy,where in-orbit computing accounts for 17%of the total onboard energy *** approach represents a significant advancement of cloud-native satellite,aiming to enhance the accuracy of in-orbit computing while simultaneously reducing communication cost.

关键词： cloud-native satellite orbital edge computing satellite inference verification test

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技术工人创新素质:一个量表的开发

科研管理 2019年第6期40卷 243-253页

作者：杨若邻姚先国郭丹中南财经政法大学公共管理学院湖北武汉430070 浙江大学公共管理学院浙江杭州310058 怀化学院经济学院湖南怀化418008

技术工人在一线生产实践中不断地摸索和总结,通过改良已有生产技术、发明新兴工艺、创造出新产品的方式来促进技术创新和科技成果的转化。人内在的创新素质是开展创新活动的源泉。本文通过国内外文献采集和行为事件访谈定性地采用扎根... 详细信息

技术工人在一线生产实践中不断地摸索和总结,通过改良已有生产技术、发明新兴工艺、创造出新产品的方式来促进技术创新和科技成果的转化。人内在的创新素质是开展创新活动的源泉。本文通过国内外文献采集和行为事件访谈定性地采用扎根研究方法和编码技术提炼技术工人创新素质,设计技术工人创新素质初始量表。然后,运用项目分析和高阶因子分析等定量研究方法分析量表构成和结构并检验量表信效度,最终确定技术工人创新素质正式量表。并以此为基础,形成技术工人创新素质测量模型。

关键词：技术工人创新素质量表开发测量模型

The impact of water quality on the formation of halogenated benzoquinones and the adsorption efficiency by activated carbon

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Journal of Environmental Sciences 2024年第1期135卷 693-702页

作者： Yongjing Wang Song Gao Xinyu Yan Songtao Wang ruolin Zhang Yan Zhou Lianhai Ren Cheng Li State Environmental Protection Key Laboratory of Food Chain Pollution Control Beijing Technology and Business UniversityBeijing 100048China Institute of Scientific and Technical Information of China Beijing 100038China Institute of Quality Standard and Testing Technology Beijing Academy of Agriculture and Forestry SciencesBeijing 100097China Key Laboratory of Cleaner Production and Integrated Resource Utilization of China National Light Industry Beijing Technology and Business UniversityBeijing 100048China

Halogenated benzoquinones(HBQs)could cause bladder cancer,but there were few related studies on the generation and *** this study,the impact of different precursors,pH,bromide concentration,and algae-derived organic matters on the formation of HBQs and the removal efficiency by activated carbon were *** was found that the chlorination of bisphenol A produced the most 2,6-dichloro-1,4-benzoquinone(2,6-DCBQ),reaching 14.86μg/L at 1 hr,followed by tyrosine,2-chlorophenol,P-hydroxybenzoic acid,trichlorophenol,and *** production of 2,6-DCBQ increased first and then decreased from 0 to 36 hr(chlorination doses 0-20 mg/L),indicating that HBQs were unstable in ***(THMs)were detected during chlorination,and the concentration increased with prolongation of reaction time.2,6-DCBQ production decreased and 2,6-dibromo-1,4-benzoquinone(2,6-DBBQ)production increased with increment bromide concentration and the bromide promoted the formation of *** production of 2,6-DCBQ decreased with increase of pH,and the maximum production was 141.38μg/L at pH of *** aeruginosa,Chlorella algae cells,and intracellular organic matters(IOM)could be chlorinated as potential precursors for *** most amount of 2,6-DCBQ was generated from algae cells of Microcystis aeruginosa,followed by Chlorella algae cells,Microcystis aeruginosa IOM,and Chlorella *** study compared the removal efficiency of HBQs by granular activated carbon(GAC)and columnar activated carbon(CAC)under different carbon doses and initial concentrations of *** was found that the removal efficiency by GAC(80.1%)was higher than that by CAC(51.8%),indicating that GAC has better control for HBQs.

关键词： HBQS DBPS Drinking water Algae derived organic matters Activated carbon

Integrated Sensing and Communication: Who Benefits More?

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ZTE Communications 2024年

作者： DU ruolin WEI Zhiqiang yang Zai Xi'an Jiaotong University

This paper compares the benefits of communication-assisted sensing and sensing-assisted communication in the context of integrated sensing and communication (ISAC). Communication-assisted sensing leverages the extensive cellular infrastructure to create a vast and cooperative sensor network， enhancing environmental perception accuracy and coverage. On the other hand， sensing-assisted communication utilizes advanced sensing technologies to improve predictive beamforming and channel estimation performance in high-frequency and high-mobility scenarios， thereby increasing communication efficiency and reliability. To validate our analysis， we present an example of channel knowledge map (CKM)-assisted beam tracking. This example demonstrates the practical advantages of incorporating CKM in enhancing beam tracking accuracy. Our analysis confirms that communication-assisted sensing may offer greater development potential due to its wide coverage and cost-effectiveness in large-scale applications.

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