Micro/nanoelectrode-based electrochemical methodology for single cell and organelle analysis

作     者：Chuchu Xu De Yang Yuchan Wang Ruolin Liu Fan Wang Zhongqun Tian Keke Hu Chuchu Xu;De Yang;Yuchan Wang;Ruolin Liu;Fan Wang;Zhongqun Tian;Keke Hu

作者机构：Department of ChemistryCollege of Chemistry&Chemical EngineeringXiamen UniversityXiamen 361005China 

出 版 物：《Nano Research》 (纳米研究（英文版）)

年 卷 期：2024年第17卷第1期

页      面：196-206页

核心收录：

学科分类：081704[工学-应用化学] 08[工学] 0817[工学-化学工程与技术] 0805[工学-材料科学与工程（可授工学、理学学位）] 0703[理学-化学] 0702[理学-物理学] 

基　　金：funding from Fundamental Research Funds for the Central Universities(No.20720220014) the National Natural Science Foundation of China(No.22204134). 

主　　题：single cell/organelle micro/nanoelectrode electrochemical measurement chemical transmitters 

摘      要：Cells are the basic unit of life.Electrochemical analysis of single cells/organelles is essential for uncovering the molecular mechanisms of physiological and pathological processes that are difficult to elucidate on a larger scale.This paper provides an overview of the commonly used fabrication methods for micro/nanoelectrodes applied in the investigations of single cells/organelles as well as the corresponding electrochemical measurements over the last four years including extracellular measurement,combination of extra and intracellular measurement,intracellular reactive oxygen species and reactive nitrogen species(ROS/RNS)measurement,and isolated organelles measurement.