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A global synthesis of the effectiveness and ecological impacts of management interventions for Spartina species

Frontiers of Environmental Science & Engineering 2023年第11期17卷 263-272页

作者： Shengyu Wang Philip A.Martin Yan Hao William J.Sutherland Gorm E.Shackelford Jihua wu ruiting Ju Wenneng Zhou Bo Li Ministry of Education Key Laboratory for Biodiversity Science and Ecological Engineering National Observations and Research Station of Wetland Ecosystems of the Yangtze EstuaryInstitute of Biodiversity Science and Institute of Eco-ChongmingSchool of Life SciencesFudan UniversityShanghai 200438China Biosecurity Research Initiative at St Catharine’s(BioRISC) St Catharine’s CollegeUniversity of CambridgeCambridgeCB21RLUK Conservation Science Group Department of ZoologyUniversity of CambridgeCambridgeCB23QZUK State Key Laboratory of Grassland Agro-Ecosystems and College of Ecology Lanzhou UniversityLanzhou 730000China Guangdong Provincial Key Laboratory of Water Quality Improvement and Ecological Restoration for Watersheds School of EcologyEnvironment and ResourcesGuangdong University of TechnologyGuangzhou 510006China Ministry of Education Key Laboratory for Transboundary Ecosecurity of Southwest China Yunnan Key Laboratory of Plant Reproductive AdaptationEvolutionary Ecology and Centre for Invasion BiologyInstitute of BiodiversitySchool of Ecology and Environmental ScienceYunnan UniversityKunming 650504China

Invasions by Spartina species pose serious threats to global coastal *** many studies have examined the effectiveness and ecological impacts of invasive Spartina management,no comprehensive global synthesis has been conducted to assess the effects of management on Spartina per se and on wider ***,we conducted a global meta-analysis of 3,459 observations from 102 studies to quantify the effects of different management interventions(physical,chemical,biological,and integrated control)on Spartina per se and native biodiversity and *** found that physical measures quickly suppressed Spartina but that their effectiveness declined over *** contrast,chemical measures decreased the abundance and growth of Spartina to a lesser degree in the early stage,but the effectiveness increased over *** management measures did not significantly decrease the diversity of native biota on the whole,but native-plant diversity significantly decreased with time after physical *** management measures did not affect abiotic factors *** results support the use of chemical measures to control invasive Spartina,although their effectiveness would depend on the time since the management *** the problem of Spartina regrowth following physical control requires improved *** hold that initial states of invaders and subsequent environmental changes after management interventions should be weighed in evaluating control efficacy.

关键词： Plant invasion Biodiversity Meta-analysis Restoration Salt marshes Treatment timing

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The Infection and Pathogenicity of SARS-CoV-2 Variant B.1.351 in hACE2 Mice

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Virologica Sinica 2021年第5期36卷 1232-1235页

作者： Qi Chen Xing-Yao Huang Ying Tian Changfa Fan Mengxu Sun Chao Zhou ruiting Li Rong-Rong Zhang Guizhen wu Cheng-Feng Qin State Key Laboratory of Pathogen and Biosecurity Beijing Institute of Microbiology and EpidemiologyAMMSBeijing 100071China School of Basic Medical Sciences Anhui Medical UniversityHefei 230032China Division of Animal Model Research Institute for Laboratory Animal ResourcesNational Institutes for Food and Drug ControlBeijing 102629China National Institute for Viral Disease Control and Prevention Chinese Center for Disease Control and PreventionBeijing 102206China

Dear Editor,Since the outbreak of COVID-19 at the end of 2019,its causative agent SARS-Co V-2 has been spreading around the world for one and half a *** the long global circulation of SARS-Co V-2,mutations in the vira... 详细信息

关键词： emerged accumulated SARS

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Modulation of Antiviral Immunity and Therapeutic Efficacy by 25-Hydroxycholesterol in Chronically SIV-Infected, ART-Treated Rhesus Macaques

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Virologica Sinica 2021年第5期36卷 1197-1209页

作者： Chunxiu wu Jin Zhao ruiting Li Fengling Feng Yizi He Yanjun Li Runhan Huang Guangye Li Heng Yang Genhong Cheng Ling Chen Feng Ma Pingchao Li Caijun Sun State Key Laboratory of Respiratory Disease Guangzhou Institutes of Biomedicine and Health(GIBH)Chinese Academy of SciencesGuangzhou 510530China School of Public Health(Shenzhen) Sun Yat-Sen UniversityGuangdong 518107China Key Laboratory of Tropical Disease Control Sun Yat-Sen UniversityMinistry of EducationGuangzhou 514400China University of Chinese Academy of Sciences Beijing 100049China Center for Systems Medicine Institute of Basic Medical SciencesChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100005China Suzhou Institute of Systems Medicine Suzhou 215123China Department of Microbiology Immunology and Molecular GeneticsUniversity of CaliforniaLos Angeles 90095USA Guangdong Landau Biotechnology Co.Ltd Guangzhou 510700China

Cholesterol-25-hydroxylase(CH25 H)and its enzymatic product 25-hydroxy cholesterol(25 HC)exert broadly antiviral activity including inhibiting HIV-1 ***,their antiviral immunity and therapeutic efficacy in a nonhuman primate model are ***,we report that the regimen of 25 HC combined with antiretroviral therapy(ART),provides profound immunological modulation towards inhibiting viral replication in chronically SIVmac239-infected rhesus macaques(RMs).Compared to the ART alone,this regimen more effectively controlled SIV replication,enhanced SIVspecific cellular immune responses,restored the ratio of CD4/CD8 cells,reversed the hyperactivation state of CD4^(+)T cells,and inhibited the secretion of proinflammatory cytokines by CD4^(^(+))and CD8^(+)T lymphocytes in chronically SIVinfected ***,the in vivo safety and the preliminary pharmacokinetics of the 25 HC compound were assessed in this RM *** together,these assessments help explain the profound relationship between cholesterol metabolism,immune modulation,and antiviral activities by 25 *** results provide insight for developing novel therapeutic drug candidates against HIV-1 infection and other related diseases.

关键词： 25-hydroxycholesterol(25HC) HIV SIV Antiretroviral therapy(ART) Macaque

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Dynamic Changes of Antibodies to SARS-CoV-2 in COVID-19 Patients at Early Stage of Outbreak

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Virologica Sinica 2020年第6期35卷 744-751页

作者： Huaqing Shu Shuzhen Wang Shunan Ruan Yaxin Wang Jiancheng Zhang Yin Yuan Hong Liu Yongran wu ruiting Li Shangwen Pan Yaqi Ouyang Shiying Yuan Peng Zhou You Shang Department of Critical Care Medicine Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China Institute of Anesthesiology and Critical Care Medicine Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China Jin-Yin-Tan Hospital Wuhan 430023China CAS Key Laboratory of Special Pathogens Wuhan Institute of VirologyCenter for Biosafety Mega-ScienceChinese Academy of SciencesWuhan 430071China

The coronavirus disease 2019(COVID-19),caused by SARS-CoV-2,has spread around the world with high *** diagnose promptly and accurately is the vital step to effectively control its *** characteristics of SARSCoV-2-specific antibodies which are important for diagnosis of infection have not been fully *** this retrospective,single-center,observational study,we enrolled the initial 131 confirmed cases of COVID-19 at Jin-Yin-Tan Hospital who had at least one-time antibody tested during their *** dynamic changes of IgM and IgG antibodies to SARS-CoV-2 nucleocapsid protein in 226 serum samples were detected by *** sensitivities of IgM and IgG ELISA detection were *** showed that the sensitivity of the IgG ELISA detection(92.5%)was significantly higher than that of the IgM(70.8%)(P\0.001).The meantimes of seroconversion for IgM and IgG were6 days and 3 days,*** IgM and IgG antibody levels peaked at around 18 days and 23 days,and then IgM fell to below the baseline level at about day 36,whereas IgG maintained at a relatively high *** conclusion,antibodies should be detected to aid in diagnosis of COVID-19 *** could be a sensitive indicator for retrospective diagnosis and contact tracing,while IgM could be an indicator of early infection.

关键词： Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2) Coronavirus disease 2019(COVID-19) Coronavirus Antibody Serology

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Structure design and load test of the small prototype for the JUNO Central Detector

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Radiation Detection Technology and Methods 2022年第4期6卷 439-450页

作者： Xiaoyu Yang Yuekun Heng Wei He Xiaoyan Ma Lei Yang Jiajie Ling Zhi wu Kaixi Huang Caishen Wang ruiting Lei Yatian Pei Xiaohui Qian Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China State Key Laboratory of Particle Detection and Electronics Beijing 100049China University of Chinese Academy of Science Beijing 100049China Dongguan University of Technology Dongguan 523808China Sun Yat-Sen University Guangzhou 510275China

Introduction The structure of the Jiangmen Underground Neutrino Observatory(JUNO)CentralDetector(CD)was designed using finite element methods(FEM).The structure of the small JUNOCDprototypewas also designed using the same structural scheme and method as those of the CD,and the load test was carried out after the accomplishment of structure design and *** The load test can help verify the performance and reliability of the mechanical monitoring system and liquid filling system of the CD,verify the consistency of FEM calculations and axial force measurement results of the sensors,and accumulate experience for the installation of the connecting *** The measurement scheme was considered and determined,and the connecting bars’axial forces under different liquid filling conditions were measured and compared with the FEM results,the consistencies of which were *** mechanical monitoring system and liquid filling system of theCDwere verified during the load test,which met the requirements of design and experiment.

关键词： Structure design Load test Numerical analysis Small prototype Central Detector JUNO

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Post-mortem tissue proteomics reveals the pathogenesis of multi-organ injuries of COVID-19

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National Science Review 2021年第11期8卷 88-91页

作者： Yang Qiu Di wu Wanshan Ning Jiqian Xu Ting Shu Muhan Huang Rong Chen Jiancheng Zhang Yang Han Qingyu Yang ruiting Li Xiaobo Yang Yaxin Wang Xiaojing Zou Shangwen Pan Chaolin Huang Yu Xue You Shang Xi Zhou State Key Laboratory of Virology Wuhan Institute of Virology Chinese Academy of Sciences Joint Laboratory of Infectious Diseases and Health Wuhan Institute of Virology and Wuhan Jinyintan Hospital Wuhan Institute of Virology Chinese Academy of Sciences Center for Translational Medicine Wuhan Jinyintan Hospital MOE Key Laboratory of Molecular Biophysics Hubei Bioinformatics and Molecular Imaging Key Laboratory Center for Artificial Intelligence Biology College of Life Science and Technology Huazhong University of Science and Technology Department of Clinical Laboratory Union Hospital Tongji Medical CollegeHuazhong University of Science and Technology Department of Critical Care Medicine Union Hospital Tongji Medical College Huazhong University of Science and Technology Joint Laboratory of Infectious Diseases and Health Wuhan Institute of Virology and Wuhan Jinyintan Hospital Wuhan Jinyintan Hospital Institute of Anesthesiology and Critical Care Medicine Union Hospital Tongji Medical CollegeHuazhong University of Science and Technology

Multi-organ injuries are a major complication of severe Coronavirus Disease2019 (COVID-19).However,its pathogenesis is barely ***,we profile host responses to fatal SARSCoV-2 infection by performing quantitative proteomics of 19 post-mortem samples of 8 different organs or tissues,including lungs,liver,intestine,kidney,

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The Effect of Ion Pairing on the Dynamics and Spectroscopy of the Strong Electrolyte Solutions

The Effect of Ion Pairing on the Dynamics and Spectroscopy o...

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第十三届全国化学动力学会议

作者： Qiang Zhang ruiting Zhang TianMin wu Wei Zhuang State Key Lab of Molecular Reaction Dynamics Dalian Institute of Chemical Physics

＜正＞We carried out series of spectral modeling based on the molecular dynamics simulation to help understanding the dynamic events in the ionic solution systems. By calculating different ionic solution spectra based on the same simulation trajectory ensemble, they achieved a better understanding of the underlying physics. Simulation suggests that ion pairing is the reason of various spectroscopic features.

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Extracorporeal membrane oxygenation in adult patients with sepsis and septic shock: Why, how, when, and for whom

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Journal of Intensive Medicine 2024年第1期4卷 62-72页

作者： Hongling Zhang Youdong Xu Xin Huang Shunyin Yang ruiting Li Yongran wu Xiaojing Zou Yuan Yu You Shang Department of Critical Care Medicine Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei430022China Department of Intensive Care Unit Affiliated Lu’an HospitalAnhui Medical UniversityLu’anAnhui237000China

Sepsis and septic shock remain the leading causes of death in intensive care *** patients with sepsis fail to respond to routine treatment and rapidly progress to refractory respiratory and circulatory failure,necessitating extracorporeal membrane oxygenation(ECMO).However,the role of ECMO in adult patients with sepsis has not been fully *** to existing studies,ECMO may be a viable salvage therapy in carefully selected adult patients with *** choice of venovenous,venoarterial,or hybrid ECMO modes is primarily determined by the patient’s oxygenation and hemodynamics(distributive shock with preserved cardiac output,septic cardiomyopathy(left,right,or biventricular heart failure),or right ventricular failure caused by acute respiratory distress syndrome).Veno-venous ECMO can be used in patients with sepsis and severe acute respiratory distress syndrome when conventional mechanical ventilation fails,and early application of veno-arterial ECMO in patients with sepsis-induced refractory cardiogenic shock may be critical in improving their chances of *** ECMO is indicated,the choice of an appropriate mode and determination of the optimal timing of initiation and weaning are critical,particularly in an experienced ECMO ***,some special issues,such as ECMO flow,anticoagulation,and antibiotic therapy,should be noted during the management of ECMO support.

关键词： Extracorporeal membrane oxygenation Sepsis Shock Acute respiratory distress syndrome(ARDS) Septic cardiomyopathy Mod

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嗜热古菌超高温α-淀粉酶在枯草芽孢杆菌中的分泌表达

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基因组学与应用生物学 2021年第5期40卷 2109-2117页

作者：檀瑞婷张康吴敬江南大学食品科学与技术国家重点实验室无锡214122 江南大学生物工程学院工业生物技术教育部重点实验室无锡214122 江南大学教育部食品安全国际合作联合实验室无锡214122

本研究将来源于嗜热古菌Pyrococcus furiosus的超高温α-淀粉酶基因在枯草芽孢杆菌中成功表达,通过信号肽筛选和伴侣蛋白基因共表达提高超高温α-淀粉酶在枯草芽孢杆菌中的分泌表达,并对重组超高温α-淀粉酶的酶学性质进行初步研究。首... 详细信息

本研究将来源于嗜热古菌Pyrococcus furiosus的超高温α-淀粉酶基因在枯草芽孢杆菌中成功表达,通过信号肽筛选和伴侣蛋白基因共表达提高超高温α-淀粉酶在枯草芽孢杆菌中的分泌表达,并对重组超高温α-淀粉酶的酶学性质进行初步研究。首先构建信号肽筛选文库,结合高通量筛选方法对枯草来源的173种信号肽进行筛选,最终筛选出一种新的信号肽AspB’,引导PFA胞外分泌表达,摇瓶发酵60 h后其酶活达到119.01 U/mL。在此基础上,共表达伴侣蛋白PrsA,使酶活进一步提高,发酵培养60 h后其酶活进一步提高12.72%,达134.15 U/mL。该菌株发酵潜力较好,摇瓶培养310 h后其酶活可达938.35 U/m L。对枯草芽孢杆菌中重组PFA的酶学性质进行测定,最适反应温度为100℃,最适反应pH值为4.5,在100℃条件下处理4 h仍有50%以上的酶活,在pH值4.5~7.0的条件下其稳定性良好。这在淀粉制糖工艺中具有重要的工业价值。

关键词：超高温α-淀粉酶枯草芽孢杆菌信号肽伴侣蛋白酶学性质

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K0.48Li0.02Na0.5(Nb1–xSbx)O3压电陶瓷的制备与性能

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硅酸盐学报 2020年第4期48卷 520-524页

作者：杨绳岩魏瑞亭吴圣扬张杨李宏林巢湖学院化学与材料工程学院安徽巢湖238000

采用微波烧结法制备了锑掺杂改性K0.48Li0.02Na0.5NbO3(KLNN)压电陶瓷,研究了锑掺杂量(x=0,0.02,0.04,0.06,0.08)对陶瓷的微观结构、表面形貌、介电性能、压电性能和铁电性能的影响。结果表明:在掺杂范围内,各组分的陶瓷样品均形成了单... 详细信息

采用微波烧结法制备了锑掺杂改性K0.48Li0.02Na0.5NbO3(KLNN)压电陶瓷,研究了锑掺杂量(x=0,0.02,0.04,0.06,0.08)对陶瓷的微观结构、表面形貌、介电性能、压电性能和铁电性能的影响。结果表明:在掺杂范围内,各组分的陶瓷样品均形成了单一的钙钛矿结构,结晶良好,晶粒均匀,说明金属锑在KLNN晶格中可以形成均匀固溶体,改善了KLNN基无铅压电陶瓷的微观结构,提高了其压电性能和铁电性能。在x=0.06时,K0.48Li0.02Na0.5(Nb0.94Sb0.06)O3陶瓷样品的Curie温度介电常数峰(εr)、单向电致应变(ε)、压电系数(d33)均达到最大值,分别为εr=5557,ε=0.08%,d33=208 pC/N。

关键词：钙钛矿五氧化二锑掺杂改性无铅压电陶瓷

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