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The In-Flight Realtime Trigger and Localization Software of GECAM

research in Astronomy and Astrophysics 2024年第10期24卷 11-24页

作者： Xiao-Yun Zhao Shao-lin Xiong Xiang-yang Wen xin-Qiao li Ce Cai Shuo Xiao Qi Luo Wen-Xi Peng dong-Ya Guo Zheng-Hua An Ke Gong Jin-Yuan liao yan-Qiu Zhang Yue Huang Lu li xing Wen Fei Zhang Jing Duan Chen-Wei Wang dong-li Shi Peng Zhang Qi-bin Yi Chao-yang li yan-bing Xu Xiao-Hua liang Ya-Qing liu Da-li Zhang Xi-lei Sun Fan Zhang Gang Chen Huan-Yu Wang Sheng yang Xiao-Jing liu Min Gao Mao-Shun li Jin-Zhou Wang xing Zhou Yi Zhao Wang-Chen Xue Chao Zheng Jia-Cong liu xing-Bo Han Jin-ling Qi Jia Huang Ke-Ke Zhang Can Chen Xiong-Tao yang dong-Jie Hou Yu-Sa Wang rui Qiao Xiang Ma Xiao-Bo li Ping Wang xin-Ying Song li-Ming Song Shi-Jie Zheng bing li Hong-Mei Zhang Yue Zhu Wei Chen jian-jian He Zhen Zhang Jin Hou Hong-Jun Wang yan-Chao Hao Xiang-Yu Wang Zong-Yuan yang Zhi-Long Wen Zhi Chang Yuan-Yuan Du rui Gao Xiao-Fei Lan yan-Guo li Gang li Xu-Fang li Fang-Jun Lu Hong Lu bin Meng Feng Shi Hui Wang Hui-Zhen Wang Yu-Peng Xu Jia-Wei yang Xue-Juan yang Shuang-Nan Zhang Chao-Yue Zhang Cheng-Mo Zhang Zhi-Cheng Tang Cheng Cheng Key Laboratory of Particle Astrophysics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences Chinese Academy of SciencesBeijing 100049China School of Information Science and Technology Southwest Jiaotong UniversityChengdu 611756China Key Laboratory of Stellar and Interstellar Physics and Department of Physics Xiangtan UniversityXiangtan 411105China Physics and Space Science College China West Normal UniversityNanchong 637002China Department of Astronomy Beijing Normal UniversityBeijing 100875China Innovation Academy for Microsatellites of CAS Shanghai 201203China Changchun University of Science and Technology Changchun 130022China Chinese Academy of Sciences South America center for Astronomy National Astronomical ObservatoriesCASBeijing 100101China

Realtime trigger and localization of bursts are the key functions of GECAM,an all-sky gamma-ray monitor launched on 2.2. December *** developed a multifunctional trigger and localization software operating in the CPU of the GECAM Electronic *** onboard software has the following features:high trigger efficiency for real celestial bursts with a suppression of false triggers caused by charged particle bursts and background fluctuation,dedicated localization algorithm optimized for both short and long bursts,and low time latency of the trigger information which is downlinked through the Global Short Message Communication service of the global BeiDou navigation *** paper provides a detailed description of the design and development of the trigger and localization software system for *** covers the general design,workflow,the main functions,and the algorithms used in the *** paper also includes on-ground trigger tests using simulated gamma-ray bursts generated by a dedicated X-ray tube,as well as an overview of the performance for real celestial bursts during its in-orbit operation.

关键词： telescopes instrumentation:detectors methods:observational

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Searching for^(76)Ge neutrinoless double beta decay with the CDEX-1B experiment

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Chinese Physics C 2024年第10期48卷 11-22页

作者： bing-Tao Zhang Jun-Zheng Wang li-Tao yang Qian Yue Ke-Jun Kang Yuan-Jing li Hai-Peng An C.Greeshma jian-Ping Chang Yun-Huan Chen jian-Ping Cheng Wen-Han dai Zhi Deng Chang-Hao Fang xin-Ping Geng Hui Gong Qiu-Ju Guo Xu-Yuan Guo li He Sheng-Ming He Jin-Wei Hu Han-Xiong Huang Tu-Chen Huang Hai-Tao Jia Xi jiang S.Karmakar Hao-bin li jian-Min li Jin li Qian-Yun li Ren-Ming-Jie li Xue-Qian li Yu-Lan li Yi-Fan liang bin liao Fong-Kay lin Shin-Ted lin Jia-Xuan liu Shu-Kui liu yan-dong liu Yu liu Yuan-Yuan liu Zhong-Zhi liu Hao Ma Yu-Cai Mao Qi-Yuan Nie Jin-Hua Ning Hui Pan Ning-chun Qi Jie Ren Xi-Chao Ruan Ze She Manoj Kumar Singh Tian-Xi Sun Chang-jian Tang Wei-You Tang yang Tian Guang-Fu Wang li Wang Qing Wang Yu-Feng Wang Yun-Xiang Wang Henry-Tsz-King Wong Shi-Yong Wu Yu-Cheng Wu Hao-yang xing rui Xu Yin Xu Tao Xue Yu-Lu yan Nan Yi chun-Xu Yu Hai-Jun Yu jian-Feng Yue Ming Zeng Zhi Zeng Feng-Shou Zhang lei Zhang Zhen-Hua Zhang Zhen-Yu Zhang Kang-Kang Zhao Ming-Gang Zhao Ji-Fang Zhou Zu-Ying Zhou Jing-Jun Zhou Key Laboratory of Particle and Radiation Imaging(Ministry of Education)and Department of engineering Physics Tsinghua UniversityBeijing 100084 Department of Physics Tsinghua UniversityBeijing 100084 Institute of Physics Academia SinicaTaipei 11529 NUCTECH Company Beijing 100084 YaLong River Hydropower Development Company Chengdu 610051 College of Nuclear Science and Technology Beijing Normal UniversityBeijing 100875 College of Physics Sichuan UniversityChengdu 610065 School of Physics Peking UniversityBeijing 100871 Department of Nuclear Physics China Institute of Atomic EnergyBeijing 102413 Sino-French Institute of Nuclear and Technology Sun Yat-sen UniversityZhuhai 519082 School of Physics Nankai UniversityTianjin 300071 Department of Physics Banaras Hindu UniversityVaranasi 221005 Department of Physics Beijing Normal UniversityBeijing 100875

We operated a p-type point contact high purity germanium(PPCGe)detector(CDEX-1B,1.008 kg)in the china Jinping Underground Laboratory(CJPL)for 500.3 days to search for neutrinoless double beta(0νββ)decay of^(76)Ge.A total of 504.3 kg⋅day effective exposure data was *** anti-coincidence and the multi/single-site event(MSE/SSE)discrimination methods were used to suppress the background in the energy region of interest(ROI,1989–2.89 keV for this work)with a factor of 2..A background level of 0.33 counts/(keV⋅kg⋅yr)was *** lower limit on the half life of^(76)Ge 0νββdecay was constrained as T_(1/2.^(0ν)>1.0×10^(2.)yr(90%C.L.),corresponding to the upper limits on the effective Majorana neutrino mass:2.7.5 eV.

关键词： neutrinoless double beta decay CDEX point-contact germanium detector ^(76)Ge

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research and realization of the parallel processing of Geant4 in Monte Carlo particle transport

Research and realization of the parallel processing of Geant...

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长城2.08国际医学物理大会暨第14届中国医学物理学术年会

作者： rui-kai dai jian-xin li lei li chun-li dong bin yan china national digital Switching system engineering and technological research center,zhengzhou

Purpose:To explore the parallelization of Geant4 Monte Carlo particle transport and to enlarge the magnitude of computation of Geant4. Materials and methods: The experiment is based on N01 which is one of the sample p...

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CEPC Technical Design Report

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Radiation Detection Technology and Methods 2024年第1期8卷 I0003-I0016,1-1091页

作者： Waleed Abdallah Tiago Carlos Adorno de Freitas Konstantin Afanaciev Shakeel Ahmad Ijaz Ahmed Xiaocong Ai Abid Aleem Wolfgang Altmannshofer Fabio Alves Weiming An rui An Daniele Paolo Anderle Stefan Antusch Yasuo Arai Andrej Arbuzov Abdesslam Arhrib Mustafa Ashry Sha Bai Yu Bai yang Bai Vipul Bairathi Csaba Balazs Philip Bambade Yong Ban Tripamo Bandyopadhyay Shou-Shan Bao Desmond P.Barber Ayse Bat Varvara Batozskaya Subash Chandra Behera Alexander Belyaev Michele Bertucci Xiao-Jun Bi Yuanjie Bi Tianjian Bian Fabrizio Bianchi Thomas Biekotter Michela Biglietti Shalva Bilanishvili Deng binglin Denis Bodrov Anton Bogomyagkov Serge Bondarenko Stewart Boogert Maarten Boonekamp Marcello Borri Angelo Bosotti Vincent Boudry Mohammed Boukidi Igor Boyko Ivanka Bozovic Giuseppe Bozzi Jean-Claude Brient Anastasiia Budzinskaya Masroor Bukhari Vladimir Bytev Giacomo Cacciapaglia Hua Cai Wenyong Cai Wujun Cai Yijian Cai Yizhou Cai Yuchen Cai Haiying Cai Huacheng Cai Lorenzo Calibbi Junsong Cang Guofu Cao jianshe Cao Antoine Chance Xuejun Chang Yue Chang Zhe Chang xinyuan Chang Wei Chao Auttakit Chatrabhuti Yimin Che Yuzhi Che bin Chen Danping Chen Fuqing Chen Fusan Chen Gang Chen Guoming Chen Hua-xing Chen Huirun Chen Jinhui Chen Ji-Yuan Chen kai Chen Mali Chen Mingjun Chen Mingshui Chen Ning Chen Shanhong Chen Shanzhen Chen Shao-Long Chen Shaomin Chen Shiqiang Chen Tianlu Chen Wei Chen Xiang Chen Xiaoyu Chen xin Chen Xun Chen Xurong Chen Ye Chen Ying Chen Yukai Chen Zelin Chen Zilin Chen Gang Chen Boping Chen chunhui Chen Hok Chuen Cheng Huajie Cheng Shan Cheng Tongguang Cheng Yunlong Chi Pietro Chimenti Wen Han Chiu Guk Cho Ming-chung Chu Xiaotong Chu Ziliang Chu Guglielmo Coloretti Andreas Crivellin Hanhua Cui Xiaohao Cui Zhaoyuan Cui Brunella D'Anzi ling-Yun dai xinchen dai Xuwen dai Antonio De Maria Nicola De Filippis Christophe De La Taille Francesca De Mori Chiara De Sio Elisa Del Core Shuangxue Deng Wei-Tian Deng Zhi Deng Ziyan Deng Bhupal Dev Tang Dewen Biagio Di Micco Ran Ding Siqin Dingl Yadong Ding Haiyi dong jianin AGH University of Science and Technology Faculty of Physics and Applied Computer ScienceKrakow Anhui University HefeiAnhui Applied Physics Department Federal Urdu University of ArtsScience and TechnologyIslamabad Banaras Hindu University Institute of ScienceVaranasi Bandirma Onyedi Eylul University Bandirma Beihang University Beijing Beijing Computational Science research center Beijing Beijing Conveyi LTD Beijing Beijing Glass research Institute Co. LtdBeijing Beijing Institute of Technology Beijing Beijing Normal University Beijing Brown University ProvidenceRI Budker Institute of Nuclear Physics Novosibirsk Cadi Ayyad University Laboratory of Fundamental and Applied PhysicsPolydisciplinary FacultyMarrakech Cairo University Giza center for Theory and Computation National Tsing Hua UniversityHsinchu Central china Normal University WuhanHubei Central South University ChangshaHunan Centro de Fisica Teorica de Particulas Universidade Tecnica de LisboaLisboa Chengdu kaitengSifang digital Radio&TV Equipment Co. LtdChengduSichuan china academy of engineering physics MianyangSichuan china building materials academy Beijing china center of Advanced Science and Technology Beijing china Institute of Atomic Energy Beijing china Jiliang University HangzhouZhejiang china Nuclear Instrument CO. LTDBeijing china University of Geosciences Beijing china University of Geosciences WuhanHubei china University of Mining and Technology XuzhouJiangsu china West Normal University NanchongSichuan Chongqing University Department of PhysicsChongqing Chulalongkorn University Bangkok City University of Hong Kong Department of PhysicsHong Kong Cockcroft Institute Daresbury Cornell University IthacaNY CPPM(AMU/IPhU&CNRS/INP) Marseille Dalian Minzu University DalianLiaoning Dalian University of Technology Department of PhysicsDalian Deutsches Elektronen-Synchrotron DESY Hamburg Dzhelepov Laboratory of Nuclear Problems of Joint Institute for Nuclear research(DLNP JINR) Dubna East china University Of Science And Technol

The Circular Electron Positron Collider(CEPC)is a large scientific project initiated and hosted by china,fostered through extensive collaboration with inter{2. *** complex comprises four accelerators:a 30 GeV linac,a 1.1 GeV Damping Ring,a Booster capable of achieving energies up to 180 GeV,and a Collider operating at varying energy modes(Z,W,H,and tt).The linac and Damping Ring are situated on the surface,while the subterranean Booster and Collider are housed in a 100 km circumference underground tunnel,strategically accommodating future expansion with provisions for a potential Super Proton Proton Collider(SPPC).The CEPC primarily serves as a Higgs *** its baseline design with synchrotron radiation(SR)power of 30 MW per beam,it can achieve a luminosity of 5×10^(34)cm^(-2.s^(-1)per interaction point(IP),resulting in an integrated luminosity of 13 ab^(-1)for two IPs over a decade,producing 2.6 million Higgs *** the SR power to 50 MW per beam expands the CEPC's capability to generate 4.3 million Higgs bosons,facilitating precise measurements of Higgs coupling at sub-percent levels,exceeding the precision expected from the HL-LHC by an order of *** Technical Design Report(TDR)follows the Preliminary Conceptual Design Report(Pre-CDR,2.15)and the Conceptual Design Report(CDR,2.18),comprehensively detailing the machine's layout,performance metrics,physical design and analysis,technical systems design,R&D and prototyping efforts,and associated civil engineering ***,it includes a cost estimate and a preliminary construction timeline,establishing a framework for forthcoming engineering design phase and site selection *** is anticipated to begin around 2.2.-2.2.,pending government approval,with an estimated duration of 8 *** commencement of experiments and data collection could potentially be initiated in the mid-2.30s.

关键词： initiated exceeding precise

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Incidence and prognosis of olfactory and gustatory dysfunctions related to SARS-CoV-2.Omicron strain infection in china:A national multi{2. survey of 35,566 individuals

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World Journal of Otorhinolaryngology-Head and Neck Surgery 2024年第2期10卷 113-120页

作者： Meng-Fan liu rui-Xia Ma Xian-Bao Cao Hua Zhang Shui-Hong Zhou Wei-Hong jiang yan jiang Jing-Wu Sun Qin-Tai yang Xue-Zhong li Ya-Nan Sun li Shi Min Wang Xi-Cheng Song Fu-Quan Chen Xiao-Shu Zhang Hong-Quan Wei Shao-Qing Yu dong-dong Zhu Luo Ba Zhi-Wei Cao Xu-Ping Xiao xin Wei Zhi-Hong lin Feng-Hong Chen chun-Guang Shan Guang-Ke Wang Jing Ye Shen-Hong Qu Chang-Qing Zhao Zhen-lin Wang Hua-bin li Feng liu Xiao-Bo Cui Sheng-Nan Ye Zheng liu Yu Xu Xiao Cai Wei Huang Ru-xin Zhang Yu-lin Zhao Guo-dong Yu Guang-Gang Shi Mei-Ping Lu yang Shen Yu-Tong Zhao Jia-Hong Pei Shao-bing Xie Long-Gang Yu Ye-Hai liu Shao-Wei Gu Yu-Cheng yang lei Cheng jian-Feng liu Graduate School of Beijing University of Chinese Medicine BeijingChina Department of Otorhinolaryngology Head and Neck Surgery China-Japan Friendship HospitalBeijingChina Department of Otorhinolaryngology Head and Neck Surgery The First People's Hospital of YinchuanYinchuanChina Department of Otorhinolaryngology The First People's Hospital of Yunnan ProvinceKunmingChina Department of Otorhinolaryngology The First Affiliated Hospital of Xinjiang Medical UniversityUrumqiChina Department of Otorhinolaryngology Head and Neck Surgery The First Affiliated Hospital of Zhejiang University School of MedicineHangzhouChina Department of Otorhinolaryngology Head and Neck Surgery Xiangya Hospital Central South UniversityChangshaChina Department of Otorhinolaryngology Head and Neck Surgery The Affiliated Hospital of Qingdao UniversityQingdaoChina Department of Otorhinolaryngology Head and Neck Surgery The First Affiliated Hospital of USTCHefeiChina Department of Otorhinolaryngology Head and Neck Surgery The Third Affiliated Hospital of Sun Yat-sen UniversityGuangzhouChina Department of Otorhinolaryngology Head and Neck Surgery Qilu Hospital of Shandong UniversityJinanChina Department of Otorhinolaryngology Head and Neck Surgery The Second Affiliated Hospital of Harbin Medical UniversityHarbinChina Department of Otolaryngology The Second Hospital of Shandong UniversityShandong UniversityJinanChina Department of Otorhinolaryngology Head and Neck Surgery Peking University People's HospitalBeijingChina Department of Otorhinolaryngology Head and Neck Surgery Yantai Yuhuangding HospitalQingdao UniversityYantaiChina Department of Otorhinolaryngology Head and Neck Surgery Xijing HospitalThe Fourth Military Medical UniversityXi'anChina Gansu Provincial center for Disease Control and Prevention LanzhouChina Department of Otorhinolaryngology Head and Neck Surgery The First Affiliated Hospital of China Medical UniversityShenyangChina Department of Otorhinolaryngology Head and Neck Surgery Tongji Hospit

Objective:This cross-sectional study aimed to determine the epidemiology of olfactory and gustatory dysfunctions related to COVID-19 in ***:This study was conducted by 45 tertiary Grade-A hospitals in *** and offline questionnaire data were obtained from patients infected with COVID-19 between December 2.,2.2.,and February 2.,*** collected information included basic demographics,medical history,smoking and drinking history,vaccination history,changes in olfactory and gustatory functions before and after infection,and other postinfection symptoms,as well as the duration and improvement status of olfactory and gustatory ***:Complete questionnaires were obtained from 35,566 *** overall incidence of olfactory and taste dysfunction was 67.75%.Being female or being a cigarette smoker increased the likelihood of developing olfactory and taste *** received four doses of the vaccine or having good oral health or being a alcohol drinker decreased the risk of such *** infection,the average olfactory and taste VAS scores were 8.41 and 8.51,respectively;after infection,they decreased to 3.69 and 4.2. and recovered to 5.83 and 6.55 by the time of the *** median duration of dysosmia and dysgeusia was 15 and 12.days,respectively,with 0.5%of patients having symptoms lasting for more than 2. *** overall self-reported improvement rate was 59.16%.Recovery was higher in males,never smokers,those who received two or three vaccine doses,and those that had never experienced dental health issues,or chronic accompanying ***:The incidence of dysosmia and dysgeusia following infection with the SARS-CoV-2.virus is high in *** and prognosis are influenced by several factors,including sex,SARS-CoV-2.vaccination,history of head-facial trauma,nasal and oral health status,smoking and drinking history,and the persistence of accompanying symptoms.

关键词： epidemiologic studies incidence olfactory disorders prognosis SARS-CoV-2 taste disorders

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Transarterial chemoembolization with PD-(L)1 inhibitors plus molecular targeted therapies for hepatocellular carcinoma(CHANCE001)

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Signal Transduction and Targeted Therapy 2023年第3期8卷 1198-1207页

作者： Hai-dong Zhu Hai-liang li Ming-Sheng Huang Wei-Zhu yang Guo-Wen Yin bin-yan Zhong Jun-Hui Sun Zhi-Cheng Jin jian-jian Chen Nai-jian Ge Wen-bin Ding Wen-Hui li Jin-Hua Huang Wei Mu Shan-Zhi Gu Jia-Ping li Hui Zhao Shu-Wei Wen yan-Ming lei Yu-Sheng Song chun-Wang Yuan Wei-dong Wang Ming Huang Wei Zhao jian-bing Wu Song Wang Xu Zhu jian-Jun Han Wei-xin Ren Zai-Ming Lu Wen-Ge xing Yong Fan Hai-Lan lin Zi-Shu Zhang Guo-Hui Xu Wen-Hao Hu Qiang Tu Hong-Ying Su Chuan-Sheng Zheng Yong Chen Xu-Ya Zhao Zhu-Ting Fang Qi Wang Jin-Wei Zhao Ai-bing Xu jian Xu Qing-Hua Wu Huan-Zhang Niu jian Wang Feng dai Dui-Ping Feng Qing-dong li Rong-Shu Shi Jia-rui li Guang yang Hai-bin Shi jian-Song Ji Yu-E liu Zheng Cai Po yang yang Zhao Xiao-li Zhu li-Gong Lu Gao-Jun Teng center of Interventional Radiology&Vascular Surgery Department of RadiologyZhongda HospitalMedical SchoolSoutheast UniversityNanjing 210009China Department of Minimally invasive Intervention The Affiliated Cancer Hospital of Zhengzhou UniversityZhengzhou 450008China Department of Interventional Radiology the Third Affiliated HospitalSun Yat-Sen UniversityGuangzhou 510630China Department of Interventional Radiology Union Hospital of Fujian Medical UniversityFuzhou 350001China Department of Interventional Radiology Jiangsu Cancer Hospital&Jiangsu Institute of Cancer Research&The Affiliated Cancer Hospital of Nanjing Medical UniversityNanjing 210009China Department of Interventional Radiology The First Affiliated Hospital of Soochow UniversitySoochow UniversitySuzhou 215006China Hepatobiliary and Pancreatic Interventional Treatment center Division of Hepatobiliary and Pancreatic SurgeryThe First Affiliated HospitalZhejiang University School of MedicineHangzhou 310003China Department of Interventional Radiology Eastern Hospital of Hepatobiliary SurgeryNavy Medical University(Second Military Medical University)Shanghai 200438China Department of Interventional Radiology Nantong First People’s HospitalNantong 226001China Department of Interventional Radiology Yancheng Third People’s HospitalYancheng 224008China Department of Minimally Invasive Interventional Therapy Sun YatSen University Cancer CenterGuangzhou 510060China Department of Vascular Surgery Southwest HospitalThird Military Medical University(Army Medical University)Chongqing 400038China. Department of Interventional Radiology Hunan Cancer HospitalChangsha 410031China Department of Interventional Oncology The First Affiliated Hospital of Sun Yat-sen UniversityGuangzhou 510080China Department of Interventional Radiology The Hospital of Nantong UniversityNantong 226001China Department of Interventional Therapy Shanxi Tumor HospitalTaiyuan 030001China Department of Interventional Radiology Tibet Autonomous Region People’s

There is considerable potential for integrating transarterial chemoembolization(TACE),programmed death-(ligand)1(PD-[L]1)inhibitors,and molecular targeted treatments(MTT)in hepatocellular carcinoma(HCC).It is necessary to investigate the therapeutic efficacy and safety of TACE com{2.ed with PD-(L)1 inhibitors and MTT in real-world *** this nationwide,retrospective,cohort study,82. HCC patients receiving either TACE plus PD-(L)1 blockades and MTT(com{2.ation group,n=376)or TACE monotherapy(monotherapy group,n=450)were included from January 2.18 to May *** primary endpoint was progression-free survival(PFS)according to modified *** secondary outcomes included overall survival(OS),objective response rate(ORR),and *** performed propensity score matching approaches to reduce bias between two *** matching,2.8 pairs were included with a predominantly advanced disease *** PFS in com{2.ation group was 9.5 months(95%confidence interval[CI],8.4-11.0)versus 8.0 months(95%CI,6.6-9.5)(adjusted hazard ratio[HR],0.70,P=0.002..OS and ORR were also significantly higher in com{2.ation group(median OS,19.2.16.1-2..3]vs.15.7 months[13.0-2..2.;adjusted HR,0.63,P=0.001;ORR,60.1%vs.32.0%;P2.ation and monotherapy groups,*** results suggest that TACE plus PD-(L)1 blockades and MTT could significantly improve PFS,OS,and ORR versus TACE monotherapy for Chinese patients with predominantly advanced HCC in real-world practice,with an acceptable safety profile.

关键词： hepatocellular targeted matching

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Fast parallel algorithm for three-dimensional distance-driven model in iterative computed tomography reconstruction

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Chinese Physics B 2015年第2期24卷 513-520页

作者：陈建林李磊王林元蔡爱龙席晓琦张瀚铭李建新闫镔 national digital Switching {2. engineering & technological R&D center

The projection matrix model is used to describe the physical relationship between reconstructed object and *** a model has a strong influence on projection and backprojection,two vital operations in iterative computed tomographic *** distance-driven model（DDM） is a state-of-the-art technology that simulates forward and back *** model has a low computational complexity and a relatively high spatial resolution;however,it includes only a few methods in a parallel operation with a matched model *** study introduces a fast and parallelizable algorithm to improve the traditional DDM for computing the parallel projection and backprojection *** proposed model has been implemented on a GPU（graphic processing unit） platform and has achieved satisfactory computational efficiency with no *** runtime for the projection and backprojection operations with our model is approximately 4.5 s and 10.5 s per loop,respectively,with an image size of 2.6×2.6×2.6 and 360 projections with a size of 512.*** compare several general algorithms that have been proposed for maximizing GPU efficiency by using the unmatched projection/backprojection models in a parallel *** imaging resolution is not sacrificed and remains accurate during computed tomographic reconstruction.

关键词： computed tomography iterative reconstruction parallelizable algorithm distance-driven model

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A draft sequence of the rice (Oryza sativa ssp. indica) genome

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Chinese Science Bulletin 2001年第23期46卷 1937-1942页

作者： YU Jun, HU Songnian, WANG Jun,li Songgang WONG Ka-Shu Gane, liU {2.,DENG Yajun, dai li, ZHOU yan,ZHANG Xiuqing, CAO Mengliang, liU Jing,SUN jiandong , TANG Jia{2., CHEN yanjiong,HUANG Xiao{2.g, liN Wei, YE Chen, TONG Wei,CONG lijuan, GENG jianing, HAN Yujun, li lin,li Wei, HU Guangqiang, HUANG Xiangang,li Wenjie, li jian, liU Zhanwei, li Long,liU jianping, Ql Qiuhui, liU Jinsong, li li,WANG Xuegang, LU Hong, WU Tingling,ZHU Miao, Nl Peixiang, HAN Hua, dong Wei,REN Xiaoyu, FENG Xiaoli, GUI Peng,li Xianran, WANG Hao, XU xin, ZHAI Wenxue,XU Zhao, ZHANG Jinsong, HE Sijie,ZHANG jianguo, XU Jichen, ZHANG Kunlin,ZHENG Xianwu, dong jianhai, ZENG Wanyong,TAO lin, CHEN Xuewei, HE Jun, liU Daofeng,TIAN Wei, TIAN Chaoguang, XIA Hongai,li Gang, GAO Hui, li Ping, CHEN Wei ,WANG Xudong, ZHANG Yong, HU jianfei,WANG Jing, liU Song, yanG jian,ZHANG Guangyu, XIONG Yuqing, li Zhijie,MAO Long, ZHOU Chengshu, ZHU Zhen,CHEN Runsheng, HAO Bailin,ZHENG Weimou, CHEN Shouyi, QUO Wei,li Guojie, liU Siqi, HUANG Guyang,TAO Ming, WANG jian, ZHU lihuang,YUAN Longping& yanG HuanmingBeijing Genomics Institute/center of Genomics & Bioinformatics, Chinese Academy of Sciences, Beijing 101300, china Hangzhou Genomics Institute/Institute of Bioinformatics of Zhejiang University/Key Laboratory of Bioinformatics of Zhejiang Province, Hangzhou 310007, china Institute of Genetics, Chinese Academy of Sciences, Beijing 100101, china national Hybrid Rice R & D center, Changsha 41012., china Laboratory of Bioinformatics, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, china College of life Sciences, Peking University, Beijing 100871, china Institute of Theoretical Physics, Chinese Academy of Sciences, Beijing 1Q0080, china digital china Ltd., Beijing 100080, china Institute of Computing Technology, Chinese Academy of Sciences, Beijing 100080, china Medical College, Xi’an Jiaotong University, Xi’an 710061, chinaThese authors contributed equally to this work.Corresponding author.Corresponden Beijing Genomics Institute/center of Genomics & Bioinformatics Chinese Academy of Sciences Beijing China Hangzhou Genomics Institute/Institute of Bioinformatics of Zhejiang University/Key Laboratory of Bioinformatics of Zhejiang Province Hangzhou China College of life Sciences Peking University Beijing China Medical College Xi’an Jiaotong University Xi’an China Institute of Genetics Chinese Academy of Sciences Beijing China Laboratory of Bioinformatics Institute of Biophysics Chinese Academy of Sciences Beijing China national Hybrid Rice R & D center Changsha China Institute of Theoretical Physics Chinese Academy of Sciences Beijing China digital china Ltd. Beijing China Institute of Computing Technology Chinese Academy of Sciences Beijing China

The sequence of the rice genome holds fundamental information for its biology, including physiology, genetics, development, and evolution, as well as information on many beneficial phenotypes of economic significance. Using a "whole genome shotgun" approach, we have pro-duced a draft rice genome sequence of Oryza sativa ssp. in-dica, the major crop rice subspecies in china and many other regions of Asia. The draft genome sequence is constructed from over 4.3 million successful sequencing traces with an accumulative total length of 2.14.9 Mb. The initial assembly of the non-redundant sequences reached 409.76 Mb in length, based on 3.30 million successful sequencing traces with a total length of 1797.4 Mb from an indica variant cultivar 93-11, giving an estimated coverage of 95.2.% of the rice genome with an average base accuracy of higher than 99%. The coverage of the draft sequence, the randomness of the sequence distribution, and the consistency of BIG-ASSEM-BLER, a custom-designed software package

关键词： rice genome draft sequences.

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Detection of an anti-angina therapeutic module in the effective population treated by a multi-target drug Danhong injection:a randomized trial

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Signal Transduction and Targeted Therapy 2021年第10期6卷 3009-3018页

作者： Jun liu Dan-Dan li Wei dong Yu-Qi liu yang Wu Da-Xuan Tang Fu-chun Zhang Meng Qiu Qi Hua Jing-Yu He Jun li Bai Du Ting-Hai Du lin-lin Niu Xue-Jun jiang Bo Cui jiang-bin Chen yang-Gan Wang Hai-Rong Wang Qin Yu Jing He Yi-lin Mao Xiao-Fang bin Yue Deng Yu-Dan Tian Qing-Hua Han Da-Jin liu li-Qin Duan Ming-Jun Zhao Cui-Ying Zhang Hai-Ying dai Ze-Hua li Ying Xiao You-Zhi Hu Xiao-Yu Huang Kun xing xin jiang Chao-Feng liu Jing An Feng-chun li Tao Tao Jin-Fa jiang Ying yang Yao-Rong dong lei Zhang Guang Fu Ying li Shu-Wei Huang li-Ping Dou Lan-Jun Sun Ying-Qiang Zhao Jie li Yun Xia Jun liu Fan liu Wen-Jin He Ying li jian-Cong Tan yang lin Ya-bin Zhou jian-Fei yang Guo-Qing Ma Hui-Jun Chen He-Ping liu Zong-Wu liu jian-Xiong liu Xiao-Jia Luo Xiao-Hong bin Ya-Nan Yu Hai-Xia Dang bing li Fei Teng Wang-Min Qiao Xiao-Long Zhu bing-Wei Chen Qi-Guang Chen chun-Ti Shen Yong-yan Wang Yun-dai Chen Zhong Wang Institute of Basic research in Clinical Medicine China Academy of Chinese Medical SciencesBeijingChina Department of Cardiology Chinese PLA General HospitalBeijingChina Department of Cardiology Dongfang Hospital Affiliated to Beijing University of Chinese MedicineBeijingChina Department of Geratology Peking University Third HospitalBeijingChina Department of Cardiology Xuan Wu HospitalCapital Medical UniversityBeijingChina Department of Cardiology Guang'anmen HospitalChina Academy of Chinese Medical SciencesBeijingChina Department of Cardiology First Affiliated Hospital of Henan University of Chinese MedicineZhengzhouHenanChina Department of Cardiology Wuhan University Renmin HospitalWuhanHubeiChina Department of Cardiology Wuhan University Zhongnan HospitalWuhanHubeiChina Affiliated Zhongshan Hospital of Dalian University DalianLiaoningChina Department of Cardiology Second Affiliated Hospital to Hunan University of Chinese MedicineChangshaHunanChina Department of Cardiology First Affiliated Hospital to Changchun University of Chinese MedicineChangchunJilinChina Department of Cardiology First Affiliated Hospital to Shanxi Medical UniversityTaiyuanShanxiChina Department of Cardiology Affiliated Hospital of Shanxi University of Chinese MedicineXianyangShanxiChina Department of Cardiology Changsha Central HospitalChangshaHunanChina Department of Cardiology Hubei Provincial Hospital of Traditional Chinese MedicineWuhanHubeiChina Department of Cardiology Shanxi Provincial People's HospitalXi'anShanxiChina Department of Cardiology Shanxi Province Hospital of Traditional Chinese MedicineXi'anShanxiChina Department of Cardiology Xi'an City Hospital of Traditional Chinese MedicineXi'anShanxiChina Department of Cardiology Shanghai Tongji HospitalShanghaiChina Department of Cardiology Shanghai Municipal Hospital of Traditional Chinese MedicineShanghaiChina Department of Cardiology The First Hospital of ChangshaChangshaHunanChina Department of Cardiology Xinhua Hospi

It's a challenge for detecting the therapeutic targets of a polypharmacological drug from variations in the responsed networks in thedfferentiated populations with complex diseases,as stable coronary heart ***,in an adaptive,31-center,randomized,double-blind trial invoving 92. patients with moderate symptomatic stable angina treated by 14-day Danhong injection(DHI),a kind of polyphamacological drug with high quality control,or placebo(0.9%saline),with 76-day following-up,we firstly confrmed that DHl couldincrease the proportion of patients with clinically significant changes on angina-frequency assessed by Seattle Angina Questionnaire(ASAQ-AF2.0)(12.78%at Day 30,95%confidence interval[C]5.86-19.71%,P=0.0003,13.82.at Day 6C0,95%CI 6.82.2..82.,P=0.0001and 8.95%at Day 90,95%CI 2.06-15.85%,P=0.01).We also found that there were no significant differences in new-onset major vascularevents(P=0.8502.and serious adverse events(P=0.9105)between DHl and *** performing the RNA sequencing in 62.selectedpatients,we developed a systemic modular approach tp identfy differentilly expressed modules(DEMs)of DHI with the Z_(summay)valueless than 0 compared with the control group,calculated by weighted gene co-expression network analysis(WGCNA),and sketched out thebasic framework on a modular map with 2. functional modules targeted by ***,the effective therapeutic module(ETM),defined as the highest corelation value with the phenotype alteration(SAQ-AF,the change in SAQ-AF at Day 30 from baseline)calculatedby WGCNA,was identifed in the population with the best effect(ASAQ-AF2.0),which is related to anticoagulation and regulation ofcholesterol *** assessed the modular flexbility of this ETM using the global topological D value based on Euclidean distance,which is corelated with phenotype alteration(r^(2.:0.82.4,P=0.019)by linear *** study identified the ant-angina therapeuticmodule in the effective population treated by the multi-target

关键词： angina injection sketch

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Paired quasi-periodic pulsations of hard X-ray emission in a solar flare

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Science china(Physics,Mechanics & Astronomy) 2023年第5期66卷 195-206页

作者： Hai-Sheng Zhao dong li Shao-lin Xiong yan-Qiu Zhang yang Su Wei Chen Yi Zhao Xiao-Bo li Jia-Cong liu Wen-Xi Peng rui Qiao xin-Qiao li Xiang-yang Wen li-Ming Song Shi-Jie Zheng xin-Ying Song Xiao-Yun Zhao Yue Huang Shuang-Nan Zhang Shuo Xiao Ce Cai Zheng-Hua An Can Chen Gang Chen Wei Chen yan-Qi Du Min Gao Ke Gong dong-Ya Guo Zhi-Wei Guo jian-jian He bin li Chao li Chao-yang li Gang li jian-Hui li Lu li Qing-xin li yan-Guo li Jing liang Xiao-Hua liang Jin-Yuan liao Xiao-Jing liu Ya-Qing liu Qi Luo Xiang Ma bin Meng Ge Ou dong-li Shi Jing-yan Shi Gong-xing Sun Xi-lei Sun You-li Tuo Chen-Wei Wang Hui Wang Jin Wang Jin-Zhou Wang Ping Wang Wen-Shuai Wang Hong Wu Sheng-Lun Xie yan-bing Xu Yu-Peng Xu Wang-Chen Xue Sheng yang Min Yao jian-Ying Ye Qi-bin Yi Chao-Yue Zhang Da-li Zhang Fan Zhang Fei Zhang Hong-Mei Zhang kai Zhang Peng Zhang Xiao-Lu Zhang Zhen Zhang Guo-Ying Zhao Shi-Yi Zhao Chao Zheng xing Zhou Yue Zhu Key Laboratory for Particle Astrophysics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China Purple Mountain Observatory Chinese Academy of SciencesNanjing 210023China University of Chinese Academy of Sciences Beijing 100049China Department of Astronomy Beijing Normal UniversityBeijing 100875China School of Computing and Artificial Intelligence Southwest Jiaotong UniversityChengdu 611756China Physics and Space Science College China West Normal UniversityNanchong 637002China Key Laboratory of Stellar and Interstellar Physics and Department of Physics Xiangtan UniversityXiangtan 411105China Institute of Astrophysics Central China Normal UniversityWuhan 430079China School of Physics Changchun University of Science and TechnologyChangchun 130022China College of Physics and engineering Qufu Normal UniversityQufu 273165China College of Physics Sciences&Technology Hebei UniversityBaoding 071002China

We investigate high time resolution data obtained by the Gravitational wave high-energy Electromagnetic Counterpart All-sky Monitor(GECAM)during the flare event on 2.2. April 2. at 01:52.*** subpeaks with durations of 4-6 s have been detected in the hard X-ray precursor phase,and the key feature is that they appear in pairs and seem like double-peak *** subpeaks are rarely observed in hard X-ray band and confirmed by the microwave obtained by Nobeyama Radio Polarimeters(NoRP)and Radio Solar Telescope Network(RSTN).While an exponential function can describe the continuum component of the time profile from the precursor to part of the impulsive *** periods of quasi-periodic pulsations(QPPs)are detected to be about 7.3 and 12.8 s for the precursor and impulsive phase,respectively,with at least 95%confidence *** paired QPPs are assumed to be double-peak QPPs and then the scenario of current loop coalescence model is found to be in good agreement with our *** precursor phase can be interpreted as the oscillating coalescence of two islands,while the impulsive phase can be interpreted as more islands to coalesce one by one to form larger islands.

关键词： solar flare QPPs loop coalescence circular-ribbon flare

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