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Real-time arrival picking of rock microfracture signals based on convolutional-recurrent neural network and its engineering application

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Journal of Rock Mechanics and Geotechnical Engineering 2024年第3期16卷 761-777页

作者： bing-rui chen Xu Wang Xinhao Zhu Qing Wang Houlin Xie State Key Laboratory of Geomechanics and Geotechnical Engineering Institute of Rock and Soil MechanicsChinese Academy of SciencesWuhan430071China University of Chinese Academy of Sciences Beijing100049China

Accurately picking P-and S-wave arrivals of microseismic(MS)signals in real-time directly influences the early warning of rock mass failure.A common contradiction between accuracy and computation exists in the current arrival picking ***,a real-time arrival picking method of MS signals is constructed based on a convolutional-recurrent neural network(CRNN).This method fully utilizes the advantages of convolutional layers and gated recurrent units(GRU)in extracting short-and long-term features,in order to create a precise and lightweight arrival picking ***,the synthetic signals with field noises are used to evaluate the hyperparameters of the CRNN model and obtain an optimal CRNN *** actual operation on various devices indicates that compared with the U-Net method,the CRNN method achieves faster arrival picking with less performance *** application of large underground caverns in the Yebatan hydropower station(YBT)project shows that compared with the short-term average/long-term average(STA/LTA),Akaike information criterion(AIC)and U-Net methods,the CRNN method has the highest accuracy within four sampling points,which is 87.44%for P-wave and 91.29%for S-wave,*** sum of mean absolute errors(MAESUM)of the CRNN method is 4.22 sampling points,which is lower than that of the other *** the four methods,the MS sources location calculated based on the CRNN method shows the best consistency with the actual failure,which occurs at the junction of the shaft and the second ***,the proposed method can pick up P-and S-arrival accurately and rapidly,providing a reference for rock failure analysis and evaluation in engineering applications.

关键词： Rock mass failure Microseismic event P-wave arrival S-wave arrival Deep learning

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Genome-wide analysis of AP2/ERF superfamily in Isatis indigotica

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Journal of Integrative Medicine 2023年第1期21卷 77-88页

作者： Liang Xiao Jun-ze Ren Qing Li Bin Yang Zhen-jiang Liu rui-bing chen Lei Zhang Department of Pharmaceutical Botany School of PharmacyNaval Medical UniversityShanghai 200433China Medical School of Nantong University Nantong 226001Jiangsu ProvinceChina Department of Pharmacy Changzheng HospitalNaval Medical UniversityShanghai 200433China School of Chemical and Environmental Engineering Shanghai Institute of TechnologyShanghai 201418China

Objective AP2/ERF(APETALA2/ethylene-responsive factor)superfamily is one of the largest gene families in plants and has been reported to participate in various biological processes,such as the regulation of biosynthesis of active ***,few studies have investigated the genome-wide role of the AP2/ERF superfamily in Isatis *** study establishes a complete picture of the AP2/ERF superfamily in *** and contributes valuable information for further functional characterization of IiAP2/ERF genes and supports further metabolic *** To identify the IiAP2/ERF superfamily genes,the AP2/ERF sequences from Arabidopsis thaliana and Brassica rapa were used as query sequences in the basic local alignment search *** analyses were conducted to investigate the protein structure,motif composition,chromosome location,phylogenetic relationship,and interaction network of the IiAP2/ERF superfamily *** accuracy of omics data was verified by quantitative polymerase chain reaction and heatmap *** One hundred and twenty-six putative IiAP2/ERF genes in total were identified from the *** genome database in this *** sequence alignment and phylogenetic analysis,the IiAP2/ERF genes were classified into 5 groups including AP2,ERF,DREB(dehydration-responsive element-binding factor),Soloist and RAV(related to abscisic acid insensitive 3/viviparous 1)*** which,122 members were unevenly distributed across seven *** alignment showed that *** and *** had 30 pairs of orthologous genes,and we constructed their interaction *** comprehensive analysis of gene expression pattern in different tissues suggested that these genes may play a significant role in organ growth and development of *** that may regulate lignan biosynthesis in roots were also preliminarily *** acid sequencing analysis revealed that the expression of 76 IiAP2

关键词： Isatis indigotica AP2/ERF Genomean alysis Expression pattern Lignan biosynthesis

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Quantitative proteomic analysis for high-throughput screening of differential glycoproteins in hepatocellular carcinoma serum

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Cancer Biology & Medicine 2015年第3期12卷 246-254页

作者： Hua-Jun Gao Ya-Jing chen Duo Zuo Ming-Ming Xiao Ying Li Hua Guo Ning Zhang rui-bing chen Research Center of Basic Medical Sciences & School of Medical Laboratory Tianjin Medical University Laboratory of Cancer Cell Biology Tianjin Medical University Cancer Institute and Hospital National Clinical Research Center for Cancer Tianjin Key Laboratory of Cancer Prevention and Therapy

Objective： Hepatocellular carcinoma （HCC） is a leading cause of cancer-related deaths. Novel serum biomarkers are required to increase the sensitivity and specificity of serum screening for early HCC diagnosis. This study employed a quantitative proteomic strategy to analyze the differential expression of serum glycoproteins between HCC and normal control serum samples. Methods： Lectin affinity chromatography （LAC） was used to enrich glycoproteins from the serum samples. Quantitative mass spectrometric analysis combined with stable isotope dimethyl labeling and 2D liquid chromatography （LC） separations were performed to examine the differential levels of the detected proteins between HCC and control serum samples. Western blot was used to analyze the differential expression levels of the three serum proteins. Results： A total of 2,280 protein groups were identified in the serum samples from HCC patients by using the 2D LC-MS/MS method. Up to 36 proteins were up-regulated in the HCC serum, whereas 19 proteins were down-regulated. Three differential glycoproteins, namely, fibrinogen gamma chain （FGG）, FOS-like antigen 2 （FOSL2）, and a-l, 6-mannosylglycoprotein 6-^-N-acetylglucosaminyltransferase B （MGATSB） were validated by Western blot. All these three proteins were up-regulated in the HCC serum samples. Conclusion： A quantitative glycoproteomic method was established and proven useful to determine potential novel biomarkers for HCC.

关键词： Glycoprotein hepatocellular carcinoma (HCC) mass spectrometry proteomics serum

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Beating the Fault-Tolerance Bound and Security Loopholes for Byzantine Agreement with a Quantum Solution

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Research 2024年第3期2023卷 445-455页

作者： chen-Xun Weng rui-Qi Gao Yu Bao bing-Hong Li Wen-Bo Liu Yuan-Mei Xie Yu-Shuo Lu Hua-Lei Yin Zeng-bing chen National Laboratory of Solid State Microstructures and School of Physics Collaborative Innovation Center of Advanced MicrostructuresNanjing UniversityNanjing 210093China Department of Physics and Beijing Key Laboratory of Opto-electronic Functional Materials and Micro-nano Devices Key Laboratory of Quantum State Construction and Manipulation(Ministry of Education)Renmin University of ChinaBeijing 100872China.

Byzantine agreement,the underlying core of blockchain,aims to make every node in a decentralized network reach *** Byzantine agreements unavoidably face two major *** is 1/3 fault-tolerance bound,which means that the system to tolerate f malicious players requires at least 3f+1 *** other is the security loopholes from its classical cryptography ***,we propose a Byzantine agreement framework with unconditional security to break this bound with nearly 1/2 fault tolerance due to multiparty correlation provided by quantum digital *** is intriguing that quantum entanglement is not necessary to break the 1/3 fault-tolerance bound,and we show that weaker correlation,such as asymmetric relationship of quantum digital signature,can also *** work strictly obeys two Byzantine conditions and can be extended to any number of players without requirements for multiparticle *** experimentally demonstrate three-party and five-party consensus for a digital *** work indicates the quantum advantage in terms of consensus problems and suggests an important avenue for quantum blockchain and quantum consensus networks.

关键词： methods. quantum signature

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Toward Artificial Peptide Nanocapsules

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Nano-Micro Letters 2024年第10期16卷 240-243页

作者： Yuan Wang bing chen Laboratory for Biomaterials and Drug Delivery Department of AnesthesiologyDivision of Critical Care MedicineBoston Children's HospitalHarvard Medical SchoolBostonMA 02115USA College of Electronic and Optical Engineering and College of Flexible Electronics(Future Technology) Nanjing University of Posts and TelecommunicationsNanjing 210023People's Republic of China

HIGHLIGHTS The formation of peptide nanocapsules is facilitated by a gradient interface,where the differential solvent concentration drives the peptides to preferentially localize and *** peptide nanocapsules,characterized by their hollow structures,demonstrated potential as carriers for targeted drug delivery.1 Introduction Peptide nanocapsules are a type of nanoscale delivery system that encapsulates active substances within a shell composed of peptides,leveraging the unique properties of peptides such as biocompatibility and biodegradability[1].Historically,the development of peptide nanocapsules was inspired primordially by the natural biological processes.

关键词： Peptide nanocapsules Self-assembly Drug delivery Nanomedicine

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2D all-organic perovskites refine flexible electronics

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Science China Materials 2024年第7期67卷 2365-2366页

作者： Wei Zhou bing chen College of Electronic and Optical Engineering and College of Flexible Electronics(Future Technology) Nanjing University of Posts and TelecommunicationsNanjing 210023China

Recent years have witnessed a paradigm shift with the advent of perovskites,a class of materials with a distinct CaTiO_(3)-type crystalline structure that show remarkable promise across a wide array of applications,including photovoltaics,photodetectors,lighting,lasers,and so *** them,the development of two-dimensional(2D)perovskites has garnered significant attention due to their tunable structures(mainly Dion-Jacobson and Ruddlesden-Popper structures)and enhanced stability in comparison with their 3D counterparts[1].Amidst the burgeoning research on perovskites,on the other side,all-organic perovskites stand out as a particularly intriguing subset[2].Unlike traditional perovskites that typically comprise all-inorganic(e.g.,CsPbBr_(3))or organic-inorganic hybrid components(e.g.,(PEA)_(2)PbI_(4)),all-organic perovskites are composed entirely of carbon-or nitrogen-based molecules.

关键词： perovskite inorganic entirely

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On the half-quantized Hall conductance of massive surface electrons in magnetic topological insulator films

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Science China(Physics,Mechanics & Astronomy) 2024年第6期67卷 127-136页

作者： rui chen Shun-Qing Shen Department of Physics The University of Hong KongHong Kong 999077China Department of Physics Hubei UniversityWuhan 430062China

In topological insulators,massive surface states resulting from local symmetry breaking were thought to exhibit a half-quantized Hall conductance,obtained from the low-energy effective model in an infinite Brillouin *** a lattice model,the surface band is composed of a combination of surface states and bulk *** massive surface states alone may not be enough to support an exact one-half quantized surface Hall conductance in a finite Brillouin zone and the whole surface band always gives an integer quantized Hall conductance as enforced by the TKNN *** explore this,we investigate the band structures of a lattice model describing the magnetic topological insulator film that supports the axion insulator,Chern insulator,and semi-magnetic topological insulator *** reveal that the gapped and gapless surface bands in the three phases are characterized by an integer-quantized Hall conductance and a half-quantized Hall conductance,*** propose an effective model to describe the three phases and show that the low-energy dispersion of the surface bands inherits from the surface Dirac *** gapped surface band manifests a nearly half-quantized Hall conductance at low energy near the center of Brillouin zone,but is compensated by another nearly half-quantized Hall conductance at high energy near the boundary of Brillouin zone because a single band can only have an integer-quantized Hall *** gapless band hosts a zero Hall conductance at low energy but is compensated by another half-quantized Hall conductance at high energy,and thus the half-quantized Hall conductance can only originate from the gapless ***,we calculate the layer-resolved Hall conductance of the *** conclusion suggests that the individual gapped surface band alone does not support the half-quantized surface Hall effect in a lattice model.

关键词： magnetic topological insulator Dirac equation half-quantized Hall conductance

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Big Theta Equals Small Theta Generically

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Acta Mathematica Sinica,English Series 2024年第3期40卷 717-730页

作者： rui chen Jia Liang ZOU Institute for Advanced Study in Mathmatics Zhejiang UniversityHangzhou 310058P.R.China Department of Mathematics University of Michigan530 Church StAnn ArborMI 48109USA

In this paper we consider the theta correspondence over a non-Archimedean local *** the homological method and the theory of derivatives,we show that under a mild condition the bigtheta lift is irreducible.

关键词： Theta correspondence derivatives

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Development of a high-repetition-rate lumped-inductance kicker magnet prototype for the beam switchyard of SHINE

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Nuclear Science and Techniques 2024年第2期35卷 20-31页

作者： Yong-Fang Liu rui-Ping Wang Jin Tong Bo Zhang Si chen Qi-bing Yuan Hai-Xiao Deng Ming Gu Bo Liu Shanghai Advanced Research Institute Chinese Academy of SciencesShanghai 201412People’s Republic of China

The Shanghai high-repetition-rate X-ray free-electron laser and extreme light facility(SHINE)operates at a maximum repetition rate of 1 *** magnets are key components that distribute electron bunches into three different undulator lines in a bunch-by-bunch *** kicker field width must be less than the time interval between bunches.A lumpedinductance kicker prototype was developed using a vacuum chamber with a single-turn *** full magnetic field strength was 0.005 *** paper presents the requirements,design considerations,design parameters,magnetic field calculations,and measurements of the kicker *** relevant experimental results are also *** pulse width of the magnetic field was approximately 600 ns,and the maximum operation repetition rate was 1 *** developed kicker satisfies the requirements for the SHINE ***,numerous recommendations for the future optimization of kicker magnets are provided.

关键词： X-ray free-electron laser Kicker magnet Beam switchyard High repetition rate Ni-Zn ferrites

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Double Moving Extremes Ranked Set Sampling Design

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Acta Mathematicae Applicatae Sinica 2024年第1期40卷 75-90页

作者： Meng chen Wang-xue chen rui Yang Department of Mathematics and Statistics Jishou UniversityJishou416000China

The traditional simple random sampling(SRS)design method is inefficient in many *** proposed some new designs to increase *** this paper,as a variation of moving extremes ranked set sampling(MERSS),double MERSS(DMERSS)is proposed and its properties for estimating the population mean are *** turns out that,when the underlying distribution is symmetric,DMERSS gives unbiased estimators of the population ***,it is found that DMERSS is more efficient than the SRS and MERSS methods for usual symmetric distributions(normal and uniform).For asymmetric distributions considered in this study,the DMERSS has a small bias and it is more efficient than SRS for usual asymmetric distribution(exponential)for small sample sizes.

关键词： double moving extremes ranked set sampling symmetric distribution efficiency

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