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高校科研管理存在的问题与提升路径研究

长春教育学院学报 2024年第4期40卷 19-23页

作者：米睿东北师范大学社会科学处

科研管理在高校工作中占有重要地位,科研评价与高校科研质量直接相关。一套成熟且完善的科研管理体系是提高高校整体实力的关键。因此,高校要积极主动探索科研管理的新思路、新途径和新机制。分析科研管理现状,有助于高校明晰面临的问... 详细信息

科研管理在高校工作中占有重要地位,科研评价与高校科研质量直接相关。一套成熟且完善的科研管理体系是提高高校整体实力的关键。因此,高校要积极主动探索科研管理的新思路、新途径和新机制。分析科研管理现状,有助于高校明晰面临的问题与挑战,进而探究新时代科研管理质量提升的有效路径。

关键词：高校科研管理质量提升

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日本生育支持政策及其对我国的启示

延安大学学报（社会科学版） 2024年第2期46卷 66-73页

作者：米瑞华刘玉延安大学经济与管理学院陕西延安716000

日本生育支持政策对我国优化生育支持政策具有借鉴作用。日本生育支持政策可归纳为平衡工作生活、帮助家庭育儿、转变婚育观念三大类,这些政策在一定程度上缓解了女性的职业和育儿冲突,缓解了家庭的育儿困难,也有利于扭转不利的生育观... 详细信息

日本生育支持政策对我国优化生育支持政策具有借鉴作用。日本生育支持政策可归纳为平衡工作生活、帮助家庭育儿、转变婚育观念三大类,这些政策在一定程度上缓解了女性的职业和育儿冲突,缓解了家庭的育儿困难,也有利于扭转不利的生育观念。但截至2021年,日本生育支持政策并没有真正解决日本的低生育问题。研究认为,我国可在现有生育支持政策的基础上,进一步构建支持家庭生育的公共服务体系,提供普惠创新型社会化育儿服务,培育和倡导新时代生育文化,为家庭提高生育意愿并将其转化为生育行为创造良好条件。

关键词：日本生育支持政策低生育率

神经酰胺及残余胆固醇与老年脑卒中患者颅内动脉粥样硬化性狭窄的相关性研究

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中华老年心脑血管病杂志 2024年第1期26卷 59-62页

作者：米蕊刘文韬高萌杨荣礼徐州医科大学第一临床医学院 221004 徐州医科大学附属医院老年医学科

目的探讨老年缺血性脑卒中(IS)患者神经酰胺(Cer)、三酰甘油葡萄糖乘积(TyG)指数、残余胆固醇(RC)与颅内动脉粥样硬化性狭窄(ICAS)的相关性。方法回顾性分析2022年1月至12月徐州医科大学附属医院收治的老年IS患者209例,根据颅内动脉狭... 详细信息

目的探讨老年缺血性脑卒中(IS)患者神经酰胺(Cer)、三酰甘油葡萄糖乘积(TyG)指数、残余胆固醇(RC)与颅内动脉粥样硬化性狭窄(ICAS)的相关性。方法回顾性分析2022年1月至12月徐州医科大学附属医院收治的老年IS患者209例,根据颅内动脉狭窄情况分为狭窄组122例和非狭窄组87例,检测患者Cer,计算TyG指数和RC水平。用Spearman相关性分析和logistic回归分析。结果与非狭窄组比较,狭窄组脂蛋白(a)、糖化血红蛋白(HbAlc)、TyG指数、RC、Cer16:0、Cer18:0、Cer24:1、Cer16:0/Cer24:0、Cer24:1/24:0、Cer18:0/24:0升高,Cer24:0降低(P<0.05,P<0.01)。Cer16:0、Cer18:0、Cer24:1、Cer16:0/24:0、Cer18:0/24:0、Cer24:1/24:0、脂蛋白(a)、HbAlc、TyG指数、RC与ICAS呈正相关(r=0.290、r=0.343、r=0.383、r=0.436、r=0.434、r=0.481、r=0.166、r=0.248、r=0.140、r=0.204,P<0.05,P<0.01),Cer24:0与ICAS呈负相关(r=-0.247,P<0.01)。Cer18:0、Cer24:1、Cer16:0/Cer24:0、Cer18:0/Cer24:0、RC是ICAS的重要影响因素(P<0.05,P<0.01)。结论老年IS患者Cer、TyG指数、RC水平较高,可能是发生ICAS的危险因素。

关键词：卒中神经酰胺类颅内动脉粥样硬化性狭窄甘油三酯葡萄糖乘积残余胆固醇

Nerve allograft regeneration and immunological tolerance of rats with sciatic nerve transplantation after intragastric pretreatment with ultraviolet B-irradiated donor splenocytes

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Neural Regeneration Research 2008年第5期3卷 517-520页

作者： rui mi Qiang Liu Dou Wu Orthopedic Department of the First Affiliated Hospital to Shanxi Medical University Taiyuan 030001 Shanxi Province China

BACKGROUND： Nerve allograft rejection is an unavoidable problem for nerve allografts. Traumatic peripheral nerve injuries are commonly reconstructed using autogenous nerve grafts. However, this form of reconstruction is limited by insufficient autologous nerves for large gap repairs and by morbidity at the nerve donor site. OBJECTIVE： To examine sciatic nerve regeneration and immune tolerance reaction after intragastric administration of ultraviolet B-irradiated （UVB） donor splenocytes. DESIGN, TIME AND SETTING： A complete randomized grouping design and controlled experiment. The experiments were conducted in the Department of Orthopedics, the First Affiliated Hospital to Shanxi Medical University, China, between March and October 2007. MATERIALS： Fourteen adult male SD rats and fourteen male Wistar rats, weighing 250-300 g, were randomly matched as donors and acceptors. A further seven male SD rats （weight 250-300 g, age 12-16 weeks） were used for nerve isografts. Immune preparations and the Epics XL flow cytometer were purchased from B-D Company, USA. A computer-assisted electromyograph machine was provided by Keypoint P, Dantel Company, Denmark. METHODS： Splenocytes from Wistar rats were isolated, purified, and cultured, and then irradiated with ultraviolet B. In the first control group （Group 1）, the SD rats received a syngeneic SD nerve isograft. In the second control group （Group 2）, the SD rats received a nerve allograft from Wistar rats without pretreatment. In the oral-tolerance treated group （Group 3）, the SD recipient rats were inoculated with 2.5×10^7 Lewis UVB-irradiated donor splenocyte cells by intestinal tract administration at seven days before transplantation. MAIN OUTCOME MEASURES：（1） The recent end and the middle and distal end of the transplanted nerve were cut at 8 and 12 weeks after operation. Recovery of nerve regeneration was measured with HE staining using the total number, density, and diameter of the nerve fibers. （2） The level of CD25＋T

关键词： sciatic nerve transplantation, homologous immune tolerance

老年糖尿病患者高敏C反应蛋白和系统性免疫炎症指数与冠状动脉狭窄程度的相关研究

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中华老年心脑血管病杂志 2024年第9期26卷 993-996页

作者：戴苏婕高萌米蕊郝敬波杨荣礼徐州医科大学研究生学院 221004 徐州医科大学附属医院老年医学科

目的探讨老年2型糖尿病患者高敏C反应蛋白(high sensitivity C-reactive protein, hs-CRP)和系统性免疫炎症指数(systemic immune-inflammation index, SII)与冠状动脉狭窄程度的相关性。方法回顾性选取2021年8月至2023年8月徐州医科... 详细信息

目的探讨老年2型糖尿病患者高敏C反应蛋白(high sensitivity C-reactive protein, hs-CRP)和系统性免疫炎症指数(systemic immune-inflammation index, SII)与冠状动脉狭窄程度的相关性。方法回顾性选取2021年8月至2023年8月徐州医科大学附属医院收治的老年2型糖尿病患者158例,根据冠状动脉血管造影结果进行Gensini评分,将患者分为轻度狭窄组(≤60分)79例、重度狭窄组(>60分)79例。用Spearman相关性分析和logistic回归分析。结果重度狭窄组hs-CRP、SII显著高于轻度狭窄组(P<0.01)。hs-CRP、SII、糖化血红蛋白、中性粒细胞、高敏肌钙蛋白T、中性粒细胞计数/淋巴细胞比值、血小板/淋巴细胞比值与Gensini评分呈正相关(r=0.424,P<0.01;r=0.367,P<0.01;r=0.207,P<0.01;r=0.259,P<0.01;r=0.187,P<0.05;r=0.317,P<0.01;r=0.256,P<0.01);糖尿病病程与Gensini评分呈负相关(r=-0.224,P<0.01)。多因素logistic回归分析显示,hs-CRP、SII为老年2型糖尿病患者冠状动脉狭窄程度的独立危险因素(OR=3.191,95%CI:1.847~5.513,P=0.000;OR=1.006,95%CI:1.004~1.009,P=0.000)。结论老年2型糖尿病患者hs-CRP、SII水平较高,可能是发生冠状动脉狭窄的独立危险因素。

关键词： C反应蛋白质冠状动脉狭窄免疫炎症指数

Dielectric and ferroelectric characteristics of Ba(Ti_(0.25)Zr_(0.25)Hf_(0.25)Sn_(0.25))O_(3)high-entropy ceramics

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Journal of Materiomics 2023年第4期9卷 634-641页

作者： rui Hu mi Bu Hang Chen Xiao Li Zhu Xiang ming Chen School of Materials Science and Engineering Zhejiang UniversityHangzhou310027China

Ba(Ti_(0.25)Zr_(0.25)Hf_(0.25)Sn_(0.25))O_(3)high-entropy ceramics were prepared by a standard solid state reaction process,and the dielectric and ferroelectric characteristics were investigated together with the *** X-ray diffraction(XRD)and energy dispersive spectroscopy(EDS)analysis demonstrated a single-phase perovskite structure in the present ceramics.A broad dielectric peak with strong frequency dispersion feature was determined,which indicated the typical relaxor nature originating from the nanoscale ferroelectric domain *** resulted from the structural distortion and chemical disorder due to high-entropy,where the long-range order of ferroelectric domains was *** homogeneous microstructure led to the reduced leakage current density and significantly improved dielectric strength,which was desired for the practical *** with the similar systems of Ba(Ti_(1-x)Zr_(x))O_(3)&Ba(Ti_(1-x)Sn_(x))O_(3),the present high-entropy ceramics indicated better relaxor ferroelectric characteristics.

关键词： High-entropy ceramic microstructure Perovskite Relaxor ferroelectric

Curative effect observation on deformed auricle treated with EarWell Infant Ear Correction System with modular parents'nursing education

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Frontiers of Nursing 2020年第2期7卷 153-159页

作者： Wei Wei Ren-Zhong Luo Zhen-Yun Huang rui mi Department of Otolaryngology Guangzhou Children and Women's Medical CenterGuangdongGuangzhou 51000China Department of Physical Medicine and Rehabilitation Guangzhou CanAm International Medical CenterGuangdongGuangzhou 51000China

Objective:To investigate the efficacy and patient satisfaction of the EarWell Infant Ear Correction System combined with modular parents'nursing education's curative effect on deformed ***:A total of 42 patients(29 boys and 13 girls;73 ears;age≤3 months)with auricle deformities who had received EarWell Infant Ear Correction System's treatment and modular parents'nursing education in Guangzhou Children and Women's Medical Center between April and October *** modular parents'education program is standardized by EarWell *** and patients'parents compared the severity of auricle deformity separately before and after the treatment by using the auricle deformities visual analogue scales(VAS)rating *** satisfaction was evaluated by using global aesthetic improvement scale(GAIS).The data collected of auricle deformities VAS and GAIS satisfaction score were applied to measure the treatment's ***:All the 42 patients(73 external ears)completed the treatment with EarWell Infant Ear Correction System and modular parents'nursing *** mean age at initiation of treatment was 37.87±19.44 days and the therapeutic time span was 47.21±17.36 *** the end of treatment,the physician's and patients'guardians rating of the severity of auricle deformity were significantly improved separately compared to the initial rating(8.33±1.27 vs.6.51±0.84;Pminor like skin eczema and irrigation;there were no severe complications such as necrosis of the skin and *** patient tolerance for the treatment was acceptable with the adequate parents'nursing *** patients'guardians were satisfied with the treatment outcomes of EarWell Infant Ear Correction System with more engagement of nursing care,the GAIS's rating were increased from pretreatment stage's 26.19%to treatment completed stage's 90

关键词： EarWell Infant Ear Correction System modular parents'nursing care education auricle deformities VAS rating system GAIS rating system

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常见无机絮凝剂除磷效果及强化絮凝研究

广州化工 2024年第6期52卷 162-164,210页

作者：沈晓腾张海涛崔红玉米瑞雪马天宇冷瑞利山东石油化工学院化学工程学院山东东营257000

研究了常见的无机絮凝剂聚合氯化铝(PAC)、硫酸铝、硫酸亚铁、聚合硫酸铁(PFS)、氯化铁在相同条件下除磷效果,结果表明:PAC>硫酸亚铁>硫酸铝>PFS>氯化铁。探究了不同pH、投加量、搅拌强度、搅拌时间、沉淀时间下PAC、硫酸亚铁与硫酸铝... 详细信息

研究了常见的无机絮凝剂聚合氯化铝(PAC)、硫酸铝、硫酸亚铁、聚合硫酸铁(PFS)、氯化铁在相同条件下除磷效果,结果表明:PAC>硫酸亚铁>硫酸铝>PFS>氯化铁。探究了不同pH、投加量、搅拌强度、搅拌时间、沉淀时间下PAC、硫酸亚铁与硫酸铝的除磷效果,对比显示PAC的除磷效果不同条件下均好于硫酸亚铁和硫酸铝。复配助凝剂(聚丙烯酰胺、草酸钠、硅藻土)强化絮凝的除磷效果研究表明,添加聚丙烯酰胺强化絮凝效果最好,最优工作条件下PAC和硫酸铝除磷率分别达到93.11%和73.89%。

关键词：絮凝除磷助凝剂

神经酰胺与老年缺血性脑卒中患者颅内外动脉粥样硬化性狭窄的相关性分析

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医学研究杂志 2024年第8期53卷 155-160页

作者：米蕊刘文韬高萌戴苏婕孙跃杨荣礼卢海龙徐州医科大学研究生学院 221004 徐州医科大学附属医院老年医学科 221002

目的探讨老年缺血性脑卒中(ischemic stroke,IS)患者神经酰胺(ceramide,Cer)、甘油三酯-葡萄糖指数(triglyceride-glucose index,TyG指数)、残余胆固醇(residual cholesterol,RC)水平对颅内外动脉粥样硬化性狭窄的评估价值。方法选取2022年1月~2023年6月于徐州医科大学附属医院住院治疗的老年IS患者447例,根据头颈部数字减影血管造影(digital subtraction angiography,DSA)所示动脉管腔情况将患者分为非狭窄组(n=144)和狭窄组(n=303),其中狭窄组进一步分为中度狭窄组(n=121)和重度狭窄+闭塞组(n=182)。收集所有患者的一般资料及基线生化资料,采用高效液相色谱串联质谱法检测患者血清Cer,计算TyG指数和RC水平。采用Spearman法分析Cer、TyG指数、RC与颅内外动脉粥样硬化性狭窄的相关性,多因素Logistic回归分析确定颅内外动脉粥样硬化性狭窄的危险因素。结果与非狭窄组比较,狭窄组Cer、TyG指数、RC、Lp(a)、糖化血红蛋白等指标明显增高(P<0.05)。多因素Logistic回归分析结果显示,Cer16:0、Cer18:0、Cer24:1、Cer24:1/Cer24:0、Cer18:0/Cer24:0、Cer16:0/Cer24:0是老年IS患者患者颅内外动脉粥样硬化性狭窄的独立危险因素。Spearman相关性分析结果显示,Cer24:0与颅内外动脉粥样硬化性狭窄呈负相关(r=-0.122,P<0.05)。受试者工作特征曲线分析结果显示,Cer24:1、Cer24:1/Cer24:0、Cer18:0/Cer24:0、Cer16:0/Cer24:0,RC、TyG指数诊断老年IS患者颅内外动脉粥样硬化性狭窄的曲线下面积分别为0.832、0.846、0.826、0.829、0.578、0.586(P<0.05)。结论老年IS患者的血清Cer、TyG指数、RC水平较高,可能是老年IS患者颅内外动脉粥样硬化性狭窄的危险因素。

关键词：神经酰胺缺血性脑卒中甘油三酯-葡萄糖指数残余胆固醇颅内外动脉粥样硬化性狭窄