检索结果-南通市图书馆

Food Science and Human Wellness 2024年

作者： Shanshan Shui Juan Chen Yan Lin Jingjing Yuan Xin Wang xian Zhang Jian liu Lei Zheng Engineering Research Center of Bio-process， Ministry of Education， Hefei University of Technology Key Laboratory of Health Risk Factors for Seafood of Zhejiang Province， College of Food Science and Pharmacy， Zhejiang Ocean University School of Food and Biological Engineering， Hefei University of Technology

During the development of diet-induced obesity， the change of energy matebolism is closely related to the function of the circadian clock in mammals. Luteolin (LU)， one of the most common natural flavonoids riched in many edible plants， can ameliorate obesity by activating adipose tissue browning， but its effect on circadian clock in this process remains poorly understood. Here we found that dietary LU improved circadian misalignment of energy expenditure in high-fat diet (HFD)-fed wild-type (WT) mice. Moreover， dietary LU efficiently elevated UCP1 levels in adipose tissue during the dark period， which was similar to the LU-increased hepatic PER2 expressions. Hepatic PPARα/RXRα/FGF21 pathway was rhythmically elevated by dietary LU in HFD-fed WT mice， whereas the promotion was inhibited in Per2-/-mice. Meanwhile， Per2 deletion abolished the effects of dietary LU on adipose tissue browning in HFD-fed mice. Further， LU treatment directly activated PPARα/RXRα/FGF21 signaling in primary cultured hepatocytes from WT mice rather than Per2-/-mice. Taken together， the deletion of the core clock component Per2 impedes LU-induced adipose tissue browning through weakening PPARα/RXRα/FGF21 pathway in mice， providing a new insight into the interplay of energy metabolism and circadian clock for the anti-obesity activity of LU.

关键词：

Endoscopic-ultrasound-guided biliary drainage with placement of electrocautery-enhanced lumen-apposing metal stent for palliation of malignant biliary obstruction:Updated meta-analysis

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Surgery 2024年第3期16卷 907-920页

作者： Zu-xiang Peng Fang-Fang Chen Wen Tang Xu Zeng Hong-Juan Du Ru-xian Pi Hong-Ming liu Xiao-Xiao Lu Department of Hepatobiliary Surgery Daping HospitalArmy Medical UniversityChongqing 400042China Department of Oncology Chongqing General HospitalChongqing UniversityChongqing 401147China Department of Gastroenterology and Hepatobiliary Surgery People’s Hospital of Fenggang CountyGuizhou 564200Guizhou ProvinceChina Hepatobiliary and Pancreatic Tumor Center Chongqing University Cancer HospitalChongqing 400030China

BACKGROUND Endoscopic ultrasound-guided biliary drainage using electrocautery-enhanced(ECE)delivery of lumen-apposing metal stent(LAMS)is gradually being re-cognized as a viable palliative technique for malignant biliary obstruction after endoscopic retrograde cholangiopancreatography(ERCP)***,most of the studies that have assessed its efficacy and safety were small and *** meta-analyses of six or fewer studies that were published 2 years ago were therefore underpowered to yield convincing *** To update the efficacy and safety of ECE-LAMS for treatment of biliary ob-struction after ERCP *** We searched PubMed,EMBASE,and Scopus databases from the inception of the ECE technique to May 13,*** outcome measure was pooled technical success rate,and secondary outcomes were pooled rates of clinical success,re-intervention,and adverse ***-analysis was performed using a random-effects model following Freeman-Tukey double-arcsine transformation in R soft-ware(version 4.1.3).RESULTS Fourteen eligible studies involving 620 participants were ultimately *** pooled rate of technical success was 96.7%,and clinical success was 91.0%.Adverse events were reported in 17.5%of *** reinter-vention rate was 7.3%.Subgroup analyses showed results were generally *** ECE-LAMS has favorable success with acceptable adverse events in relieving biliary obstruction when ERCP is *** consistency of results across most subgroups suggested that this is a generalizable approach.

关键词： Biliary obstruction Biliary drainage Electrocautery-enhanced lumen-apposing metal stents Endoscopic ultrasound Endoscopic retrograde cholangiopancreatography failure

A widely used nonionic surfactant with desired functional groups as aqueous electrolyte additives for stabilizing Zn anode

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Rare Metals 2024年第8期43卷 3692-3701页

作者： Yue-xian Song Xiao-Feng Wang Cai-Bin liu Kai-Xuan Guo Xu-Huan Guo Xiao-Bin Zhong Yao-Hui Zhang Kai Wang Hui-Juan Guo Li-Xin Zhang Jun-Fei Liang School of Energy and Power Engineering North University of ChinaTaiyuan 030051China Key Laboratory of Green Chemical Process of Ministry of Education Hubei Key Laboratory of Novel Chemical Reactor and Green Chemical TechnologySchool of Chemical Engineering and PharmacyWuhan Institute of TechnologyWuhan 430073China Shanxi Provincial Key Laboratory for High Performance Battery Materials and Devices Taiyuan 030051China

Aqueous Zn-ion batteries(AZIBs) have emerged as potential candidates for Li-ion batteries due to their intrinsic safety and high ***,metallic Zn anodes encounter dendrite growth and water-induced corrosion,rendering poor stability and severe irreversibility at the electrode/electrolyte interface during *** stabilize the Zn anode,we report a low-cost and effective nonionic surfactant,Tween-20 polymer,as an electrolyte additive for *** Tween-20,sequential oxyethylene groups tended to be preferentially adsorbed on the Zn electrode to form a shielding layer for regulating uniform Zn ***,the hydrophobic hendecyl chains prevented H_(2)O-induced corrosion on the Zn anode *** from the desired functional groups,when only trace amounts of Tween-20(0.050 g·L^(-1)) were used,the Zn anode displayed good cycling stability over 2170 h at10 mA·cm^(-2) and a high average Coulombic efficiency of98.94% over 1000 *** Tween-20 polymer can also be effectively employed in MnO_(2)/Zn full *** their toxicity,price and amount of usage,these surfactant additives provide a promising strategy for realizing the stability and reversibility of high-performance Zn anodes.

关键词： Zn anode Dendrite growth Tween-20 polymer Surfactant additive Aqueous electrolyte

Enhanced photothermal dehydration of methanol over W_(18)O_(49)/Au/SAPO-34 catalysts with broadened light absorption

在线全文

学校读者我要写书评

暂无评论

Rare Metals 2024年第3期43卷 1139-1152页

作者： Ya-Qin Tang Meng-Xia Yan Chang-Qian Lu Shao-Yuan Li Kui-xian Wei Tao Qu Wen-HuiMa Yong-Nian Dai Kong-Zhai Li Da-Jun Luo Xue-Liang Zhang Yi-Ke liu Faculty of Metallurgical and Energy Engineering Kunming University of Science and TechnologyKunming650093China School of Materials and Energy Engineering Guizhou Institute of TechnologyGuiyang550003China

Methanol-to-olefins(MTO)process is one of the most critical pathways to produce low carbon ***,the reaction is driven by thermal catalysis,which inevitably needs to consume large amounts of fossil *** a new technique to substitute for the fuel burning is urgent for MTO process to improve the industry prospects and ***,we report a novel W_(18)O_(49)/Au/SAPO-34(W/Au/S),a multifunctional photothermal catalyst for the MTO reaction.A high methanol conversion was achieved under xenonum(Xe)lamp irradiation,yielding methyl ether(ME)and ethylene as the main *** optimized W/Au/S catalysts showed ethylene yield as high as 250μmol in 60 min,which was 2.5 times higher than that of Au/*** physiochemical characterization revealed that the SAPO-34 molecular sieves were surrounded by Au and W_(18)O_(49)nanoparticles,which exhibited a strong localized surface plasmon resonance excitation around 540 nm and light absorption beyond 500 *** multifunctional catalysts showed a strong photothermal effect,arising from the broadened light absorption of Au and W_(18)O_(49)nanoparticles,leading to a temperature as high as 250℃on the surface of the *** study showed that the superior ethylene selectivity of W/Au/S catalysts was attributed to the moderating acidic sites of W_(18)O_(49)for methanol dehydration to *** research may provide new insight for designing heterostructures to improve photo-to-chemical conversion performance and is expected to accelerate progress toward the excellent multifunctional photothermal catalysts with broad light absorption for methanol activation and C-C bond formation.

关键词： Methanol conversion Ethylene Photothermal catalysis W_(18)O_(49) BrΦnsted-acid

在线全文

学校读者我要写书评

暂无评论

基于壳聚糖的复合抑菌空气滤料制备与评估

东北大学学报（自然科学版） 2024年第2期45卷 270-275页

作者：柳静献赵琪东北大学资源与土木工程学院辽宁沈阳110819

由于新冠疫情的暴发,人们对于室内空气质量有了更高的要求.探索既能过滤细微颗粒物,还能抑制和消杀微生物细菌、防止二次污染的过滤材料具有重要意义.以质量分数为1%的聚四氟乙烯(PTFE)乳液配制出不同壳聚糖质量浓度的浸渍液,利用直接... 详细信息

由于新冠疫情的暴发,人们对于室内空气质量有了更高的要求.探索既能过滤细微颗粒物,还能抑制和消杀微生物细菌、防止二次污染的过滤材料具有重要意义.以质量分数为1%的聚四氟乙烯(PTFE)乳液配制出不同壳聚糖质量浓度的浸渍液,利用直接浸渍后处理工艺制备出壳聚糖/涤纶/聚四氟乙烯复合抑菌空气滤料.利用大肠杆菌为实验菌落验证其抑菌性能,并对其织物特性、捕集效率及压差特性进行了研究.结果表明,壳聚糖质量浓度为12.5 mg/mL时复合滤料初始阻力最小,对PM_(2.5)粒子捕集效率达到93.88%,品质因子为0.02013,分别比原始滤料提高19.56%,0.0044,且对大肠杆菌的抑菌率为84.12%.综上所述,壳聚糖质量浓度为12.5 mg/mL,PTFE乳液质量分数为1%的浸渍液制备的壳聚糖/涤纶/聚四氟乙烯复合抑菌空气滤料兼具良好的过滤能力与抑菌效果.

关键词：壳聚糖复合抑菌空气滤料抑菌捕集效率过滤性能

维普期刊数据库博看期刊

PVDF纳米纤维膜对工业除尘滤料的性能强化

在线全文

学校读者我要写书评

暂无评论

东北大学学报（自然科学版） 2024年第3期45卷 422-429页

作者：柳静献杜月东北大学资源与土木工程学院辽宁沈阳110819

为了利用聚偏氟乙烯(PVDF)纤维膜的细直径和热/压电性提升过滤效率,用静电纺丝方法制备了PVDF纤维膜,通过SEM和XRD表征了PVDF纤维膜形貌和β晶相转化,并将PVDF纤维膜附着在PPS滤料上制备成PPS/PVDF复合滤料,对其过滤效率及压差特性进行... 详细信息

为了利用聚偏氟乙烯(PVDF)纤维膜的细直径和热/压电性提升过滤效率,用静电纺丝方法制备了PVDF纤维膜,通过SEM和XRD表征了PVDF纤维膜形貌和β晶相转化,并将PVDF纤维膜附着在PPS滤料上制备成PPS/PVDF复合滤料,对其过滤效率及压差特性进行了评估.结果表明:PVDF纤维膜无串珠结构,纤维直径分布在270~780 nm,中值427.3 nm,晶型结构以β晶相为主.随着风速升高,PPS/PVDF纤维膜复合滤料过滤效率下降更小,证明PVDF纤维膜的压电效应对微细粒子过滤效率有改善作用.随着温度的提高,PVDF纤维膜呈现热电性,复合滤料的过滤效率上升,当温度升高到70℃,其对小粒径0.3μm粒子过滤效率提升幅度最大为28.37%.

关键词：过滤效率压差特性聚偏氟乙烯压电性热电性

维普期刊数据库博看期刊

在线全文

学校读者我要写书评

暂无评论

《中华道藏》所录敦煌道经订补

海南大学学报(人文社会科学版) 2024年第1期42卷 189-195页

作者：刘显嘉应学院文学院广东梅州514015

《中华道藏》所录敦煌道经或可弥补文献记载之不足,反映河西道教发展的状况;或可存佚补缺、纠谬辨伪,解决道教研究中一些悬而难决的问题,具有极高的研究价值。但由于敦煌文献整理工作专业性很强《,中华道藏》又成于众手,其所录敦煌道经... 详细信息

《中华道藏》所录敦煌道经或可弥补文献记载之不足,反映河西道教发展的状况;或可存佚补缺、纠谬辨伪,解决道教研究中一些悬而难决的问题,具有极高的研究价值。但由于敦煌文献整理工作专业性很强《,中华道藏》又成于众手,其所录敦煌道经中难免会存在一些文字和标点问题,影响读者的阅读使用。兹通过覆核敦煌写本真迹,对其中25则录文试作订补,为一家之见,供《中华道藏》异日修订时参考。

关键词：中华道藏敦煌道经录文订补

维普期刊数据库博看期刊

The Fusion of Temporal Sequence with Scene Priori Information in Deep Learning Object Recognition

在线全文

学校读者我要写书评

暂无评论

Open Journal of Applied Sciences 2024年第9期14卷 2610-2627页

作者： Yongkang Cao Fengjun liu xian Wang Wenyun Wang Zhaoxin Peng School of Mechanical Engineering Hunan University of Science and Technology Xiangtan China

For some important object recognition applications such as intelligent robots and unmanned driving, images are collected on a consecutive basis and associated among themselves, besides, the scenes have steady prior features. Yet existing technologies do not take full advantage of this information. In order to take object recognition further than existing algorithms in the above application, an object recognition method that fuses temporal sequence with scene priori information is proposed. This method first employs YOLOv3 as the basic algorithm to recognize objects in single-frame images, then the DeepSort algorithm to establish association among potential objects recognized in images of different moments, and finally the confidence fusion method and temporal boundary processing method designed herein to fuse, at the decision level, temporal sequence information with scene priori information. Experiments using public datasets and self-built industrial scene datasets show that due to the expansion of information sources, the quality of single-frame images has less impact on the recognition results, whereby the object recognition is greatly improved. It is presented herein as a widely applicable framework for the fusion of information under multiple classes. All the object recognition algorithms that output object class, location information and recognition confidence at the same time can be integrated into this information fusion framework to improve performance.

关键词： Computer Vison Object Recognition Deep Learning Consecutive Scene Information Fusion

靶向泛素特异性蛋白酶1小分子抑制剂的研究进展

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

药学学报 2024年第4期59卷 866-885页

作者：徐嘉浩李宏瑞把睿先刘同超熊兵江西中医药大学药学院江西南昌330004 沈阳药科大学辽宁沈阳110016 中国科学院上海药物研究所上海201203 长三角药物高等研究院江苏南通226133

泛素特异性蛋白酶1(ubiquitin-specific protease 1,USP1)是在癌症研究中越发受关注的去泛素化酶之一。USP1在许多肿瘤中过度表达,现已发现USP1能通过调控与肿瘤相关的多种蛋白质的表达来控制肿瘤的发生和进展,如SIK2、GSK-3β和Bcl-2... 详细信息

泛素特异性蛋白酶1(ubiquitin-specific protease 1,USP1)是在癌症研究中越发受关注的去泛素化酶之一。USP1在许多肿瘤中过度表达,现已发现USP1能通过调控与肿瘤相关的多种蛋白质的表达来控制肿瘤的发生和进展,如SIK2、GSK-3β和Bcl-2等。基因敲除或药物抑制USP1能有效抑制肿瘤,同时还有望解决顺铂以及聚腺苷二磷酸核糖聚合酶(poly ADP-ribose polymerase,PARP)抑制剂耐药性问题。本综述介绍了USP1的结构、功能以及USP1靶点与肿瘤的关系,并系统地总结2013年至2023年公开的USP1小分子抑制剂的结构、活性以及构效关系。最后,本综述讨论了开发USP1小分子抑制剂的挑战和机遇。

关键词：泛素特异性蛋白酶1 小分子抑制剂合成致死耐药性构效关系

ANN-FLUS模型在历史耕地分布变化重建上的应用——以1885—2000年的越南为例

在线全文

学校读者我要写书评

暂无评论

自然资源学报 2024年第6期39卷 1473-1492页

作者：刘娴刘浩龙中国科学院地理科学与资源研究所陆地表层格局与模拟重点实验室北京100101 中国科学院大学北京100049

历史土地利用及其覆被的变化对于理解不同时期的人地关系具有重要指导意义。传统的耕地开垦优先度模型未考虑土地利用转换规则及邻域效应,重建精度不高。基于多源史料提取越南1885—2000年5个关键年份耕地总量及其9个驱动因素,并应用有... 详细信息

历史土地利用及其覆被的变化对于理解不同时期的人地关系具有重要指导意义。传统的耕地开垦优先度模型未考虑土地利用转换规则及邻域效应,重建精度不高。基于多源史料提取越南1885—2000年5个关键年份耕地总量及其9个驱动因素,并应用有大数据处理和土地转换规律挖掘优势的ANN-FLUS模型探讨耕地分布变化。结果表明:(1)耕地总量由1532千hm^(2)增至6200千hm^(2),其变化以1940年代为转折阶段而表现出前快、后慢的差异;(2)耕地历来集中在红河、湄公河三角洲以及中部沿海平原,其在全国尺度上开发模式由“聚点式”缓慢延伸逐渐转变为“散点”式迅速扩张;(3)ANN-FLUS模型在越南1950年耕地分布格局上的重建精度为Kappa系数0.65,显著优于开垦优先度模型(0.54)及HYDE 3.2数据集模型(0.50)。

关键词：历史耕地分布变化机器学习 ANN-FLUS模型重建越南