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耳穴三部曲联合腹部经穴推拿对结肠镜检查患者肠道清洁情况及腹痛腹胀程度的作用观察

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北京中医药 2024年第7期43卷 776-779页

作者：许冰胡海荣陈默岩石磊刘苗祁欢北京中医药大学东方医院脾胃肝胆科北京100078 北京中医药大学东方医院护理部北京100078

目的观察耳穴三部曲联合腹部经穴推拿对结肠镜检查患者肠道清洁情况及腹痛、腹胀程度的改善作用。方法选择2022年3月—2023年1月于北京中医药大学东方医院住院行结肠镜检查的患者60例,采用随机数字表法将患者分为耳穴组、推拿组、耳穴+... 详细信息

目的观察耳穴三部曲联合腹部经穴推拿对结肠镜检查患者肠道清洁情况及腹痛、腹胀程度的改善作用。方法选择2022年3月—2023年1月于北京中医药大学东方医院住院行结肠镜检查的患者60例,采用随机数字表法将患者分为耳穴组、推拿组、耳穴+推拿(观察)组3组,各20例。患者均口服聚乙二醇电解质散。耳穴组检查前1天晨起,患者取坐位,应用耳穴三部曲进行干预;推拿组分别于检查前1、2、3天进行腹部经穴推拿;观察组给予耳穴三部曲联合腹部经穴推拿进行干预。比较3组肠道准备情况[肠道准备量表(BBPS)评分、肠道准备清洁合格率、肠道气泡评分、肠道气泡易于观察率]及腹痛(VAS)评分、腹胀程度评分。结果观察组BBPS评分、肠道准备清洁合格率、肠道气泡易于观察率均高于耳穴组、推拿组(P<0.05),肠道气泡评分低于耳穴组、推拿组(P<0.05)。观察组腹痛VAS、腹胀程度评分均低于耳穴组、推拿组(P<0.05)。结论耳穴三部曲联合腹部经穴推拿能够提高结肠镜检查患者的肠道清洁程度,改善其肠镜检查后腹痛、腹胀。

关键词：耳穴贴压腹部经穴推拿结肠镜检查肠道准备腹痛腹胀

Is There Re-staging Surgery Necessity for Borderline Ovarian Tumors

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当代医学科学(英文) 2023年第4期43卷 822-830页

作者： Li-li GUO Xiao-yan KANG Yue SU Xiao-yu liu Xue WU Wan XIE Yu-huan liu Chang-yu WANG Department of Obstetrics and Gynecology Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China

Objective:This study assessed the necessity of surgical re-staging in women with borderline ovarian tumors(BOTs)and evaluated the impact of complete surgical staging,lymphadenectomy,and omentectomy on disease recurrence and ***:We retrospectively reviewed the medical records of patients with BOTs.A total of 901 patients were eligible for inclusion in the study,and we evaluated some of the variables and clinical/surgical characteristics of the *** effects of the type of surgical procedure,surgical staging,and complete or incomplete staging on recurrence were *** rates of disease-free survival,overall survival,and recurrence were compared according to complete surgical staging.A Cox regression analysis was performed to identify potential prognostic factors,and survival curves were constructed using the Kaplan-Meier ***:The overall recurrence rate was 13.9%,and recurrence was comparable between the complete surgical staging group and the incomplete groups(P>0.05).The performance of complete surgical staging did not show an effect on long-term survival,and complete surgical staging,omentectomy,and lymphadenectomy had no effect on *** multivariate analyses,only radical surgery and adjuvant chemotherapy were risk factors for the recurrence of ***,we found that omentectomy led to a relatively low recurrence rate in patients with International Federation of Gynecology and Obstetrics(FIGO)stage>Ⅰ(P=0.022).Conclusion:Our results suggest that complete surgical staging should be considered a standard treatment for patients with advanced stage BOTs but not for those at FIGO stageⅠ.It might be safe to reduce the scope of surgical procedures in patients with early-stage ***,it is not necessary to perform re-staging operations for BOTs with a macroscopically normal extra-ovarian appearance.

关键词： borderline ovarian tumor staging surgery management recurrence

Efficient delivery of clay-based nanovaccines to the mouse spleen promotes potent anti-tumor immunity for both prevention and treatment of lymphoma

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Nano Research 2021年第5期14卷 1326-1334页

作者： Ling-Xiao Zhang Ying-Bo Jia Ya-Ru huang Hui-Na liu Xia-Mei Sun Ting Cai rui-Tian liu Zhi Ping Xu Hwa Mei Hospital University of Chinese Academy of Sciences(Ningbo No.2 Hospital)Ningbo315010China Ningbo Institute of Life and Health Industry University of Chinese Academy of SciencesNingbo315010China Australian Institute for Bioengineering and Nanotechnology The University of QueenslandSt LuciaQLD4072Australia State Key Laboratory of Biochemical Engineering Institute of Process EngineeringChinese Academy of SciencesBeijing100190China School of Chemical Engineering University of Chinese Academy of SciencesBeijing100049China

Cancer therapeutic nanovaccines are ideal tools to inhibit tumor growth and provide the body with continuous protecting immune ***,the conventional subcutaneous(SC)vaccination normally induces limited anti-tumor immune responses with low therapeutic ***,we devised clay-based nanovaccines and directly delivered them to the spleen via intravenous(IV)injection to induce the stronger anti-tumor immunity with higher efficacy for tumor prevention and *** clay,i.e.,layered double hydroxide(LDH)was prepared as nanoadjuvant with the average size from 77 to 285 nm and co-loaded with the model antigen ovalbumin(OVA)and bioadjuvant CpG to form CpG/OVA-LDH(CO-LDH)*** found that CO-LDH-215(the size of LDH was 215 nm)promoted dendritic cells to present the most antigen,and moreover showed the highest spleen enrichment(~1.67%of CO-LDH-215 enriched in the spleen at 24 h post IV injection).The in vivo immunologic data showed that CO-LDH-215 induced the most potent anti-tumor immune responses and completely prevented the growth of E.G7-OVA tumor in the mouse ***,IV injected CO-LDH-215 nanovaccine more effectively delayed tumor growth than that SC injected,largely due to the direct and quick delivery of more nanovaccines to the *** study demonstrates that the therapeutic efficacy of nanovaccines can be greatly enhanced by targeted delivery of nanovaccines to the spleen via the proper vaccination route.

关键词： cancer immunotherapy nanovaccine layered double hydroxide targeted delivery to the spleen lymphoma

Emission Behaviors of Submicron Particles(PM_(1))Generated by the Combustion of Sesame Stalk after Combined Water Washing and Carbonization Pretreatment

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Energy Engineering 2021年第3期118卷 473-485页

作者： Tianyu liu Chang Wen Wenyu Wang Kai Yan Yongjun Xia rui Li Juan liu Yang Zhang State Key Laboratory of Coal Combustion School of Energy and Power EngineeringHuazhong University of Science and TechnologyWuhan430074China Department of New Energy Science and Engineering School of Energy and Power EngineeringHuazhong University of Science and TechnologyWuhan430074China China-EU Institute for Clean and Renewable Energy Huazhong University of Science and TechnologyWuhan430074China State Grid Jiangxi Electric Power Science Research Institute Nanchang330096China

Pretreatment before biomass combustion is significant for its efficient utilization and that combined water washing and carbonization can be *** agricultural processing residues sesame stalk was selected and carried out two pretreatments separately,i.e.,water washing-torrefaction(W-T)and torrefaction-water washing(T-W),to explore the effect on the fuel properties,combustion characteristics and particulate matter(PM)*** obtained biochar was also combusted under air and oxy50(CO_(2):O_(2)=50:50)conditions for the sake of investigating the effect of pretreatment and combustion *** results indicate that,W-T and T-W both not only have great effect on the improvement of fuel properties but also reduce the content of water-soluble elements like K,Cl,*** to the difference in hydrophobicity,the biochar obtained by W-T have the optimal fuel *** the same time,the pretreatment also hinder the combustion in a certain extent in which the comprehensive combustion characteristics(SN)show a downward ***,both two pretreatments have obvious benefit on the reduction of PM_(1)emission and W-T have the best effect related to the higher removal efficiency of inorganic elements(especially K+Na+Cl+S).Under oxy50 condition,the oxygen concentration and combustion temperature is higher,improving the sulfation of K and vaporization of Ca,P and Mg which result in weakening in the pretreatment reduction effect on PM_(1)emission.

关键词： Biomass torrefaction water washing oxy-fuel PM_(1)

超声生物显微镜在术前评估先天性上睑下垂眼睑解剖结构中的应用

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临床眼科杂志 2024年第4期32卷 343-349页

作者：余瑜李睿刘嫣祁俏然林明李瑾上海交通大学医学院附属第九人民医院眼科 200041

目的初步探究超声生物显微镜(UBM)作为先天性上睑下垂(CP)术前眼睑解剖结构评估工具的可行性,并分析患侧眼提上睑肌及腱膜的病理改变。方法前瞻性病例研究。选取10例单眼先天性上睑下垂的初诊患者入组,根据病情的严重程度分为中度组(5例... 详细信息

目的初步探究超声生物显微镜(UBM)作为先天性上睑下垂(CP)术前眼睑解剖结构评估工具的可行性,并分析患侧眼提上睑肌及腱膜的病理改变。方法前瞻性病例研究。选取10例单眼先天性上睑下垂的初诊患者入组,根据病情的严重程度分为中度组(5例)和重度组(5例)。利用UBM(SW-3200L,35MHz)对患者双侧上眼睑进行观察并成像。将患侧眼的UBM图像与其术中所见及术后病理相对照,进一步比较患侧眼提上睑肌(提肌)及腱膜的免疫组化结果并作初步定量分析。结果UBM能对包括眼轮匝肌、腱膜、睑板和提上睑肌-Müller肌复合体在内的眼睑结构清晰成像。术前UBM成像发现的腱膜变薄、腱膜后退及腱膜劈裂在术中观察得以印证;术前UBM成像发现的脂肪浸润在术中观察和术后病理中均得以证实。关于脂肪的浸润,中度组中,脂肪组织在腱膜中的浸润密度高于在提肌中(P0.05);重度组中,胶原纤维在腱膜中的增生相比于提肌显著增高(P<0.01);此外,重度组提肌中胶原纤维的增生程度稍高于中度组提肌(P<0.05),而重度组腱膜中胶原纤维的增生程度显著高于中度组腱膜(P<0.01)。结论UBM可作为先天性上睑下垂患者术前眼睑解剖结构评估的有效无创检查,重度患者腱膜的组织结构比提肌更为紊乱。

关键词：超声生物显微镜提上睑肌提上睑肌腱膜先天性上睑下垂

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高校口腔实验室建设管理的探讨

继续医学教育 2024年第2期38卷 149-152页

作者：任群利李小兰王苗胡欢王倩刘建国遵义医科大学贵州省高校特色微生物资源开发重点实验室贵州遵义563003 遵义医科大学口腔医学院贵州遵义563003

口腔实验室是培养医学生以及为临床医生和教学人员开展科研和教学工作的重要场所。口腔实验室建设规范管理涉及学生、师资、仪器、环境、安全等问题。实验室需要构建丰富的学术型教师和临床型教师双师型师资力量;通过整理(seiri)、整顿(... 详细信息

口腔实验室是培养医学生以及为临床医生和教学人员开展科研和教学工作的重要场所。口腔实验室建设规范管理涉及学生、师资、仪器、环境、安全等问题。实验室需要构建丰富的学术型教师和临床型教师双师型师资力量;通过整理(seiri)、整顿(seiton)、清扫(seiso)、清洁(seiketsu),素养(shitsuke)营造清洁的环境,建立健全实验室制度;通过“专检”与“群查”、“人检”与“机查”、“飞检”与“例查”、“点检”与“面查”、“闭检”与“必查”的结合对实验室安全进行检查,建立完备的安全制度。此外,管理人员实行网上预约构建仪器设备的动态监测管理机制,营造良好的环境,继而对学生进行本硕生混合管理培养,端正学生学术态度和提升临床技能。最后,采用以问题为基础的教学法(problem-based learning,PBL),有利于对学生的高效培养,有利于产出高质量的产品和成果,从而充分发挥实验室科研水平和创新能力,培养复合型医学人才和卓越拔尖人才。

关键词：口腔实验室学生师资环境安全管理

德州市非物质文化遗产空间分布特征与影响因素研究

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北京建筑大学学报 2024年第2期40卷 15-23页

作者：李春青朱禹瀚刘山石陈睿张曼北京建筑大学建筑与城市规划学院北京100044

研究非物质文化遗产空间分布特征和影响因素,对城市更新中的非遗项目保护、地域文化传承、城市特色塑造具有支撑与促进作用。德州市作为世界文化遗产京杭大运河沿岸历史城市,非物质文化遗产资源丰富且影响广泛,但学界对德州市市域范围... 详细信息

研究非物质文化遗产空间分布特征和影响因素,对城市更新中的非遗项目保护、地域文化传承、城市特色塑造具有支撑与促进作用。德州市作为世界文化遗产京杭大运河沿岸历史城市,非物质文化遗产资源丰富且影响广泛,但学界对德州市市域范围内的非遗资源及其空间分布特征和内在影响因素研究较薄弱,这不利于我们在城市建设中保护、传承和利用非遗。因此,以整理的德州市118项非遗项目为研究对象,通过ArcGIS的平均最近邻、核密度分析、多环缓冲区分析等工具,实现德州市非遗空间分布的可视化表达,并总结非遗空间分布特征及其影响因素,以期能为非遗的科学保护、合理利用和城市更新设计提供支撑。

关键词：非物质文化遗产空间分布城市更新德州市 ArcGIS

Rice cultivation changes and its relationships with geographical factors in Heilongjiang Province,China

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Journal of Integrative Agriculture 2017年第10期16卷 2274-2282页

作者： LU Zhong-jun SONG Qian liu Ke-bao WU Wen-bin liu Yan-xia XIN rui ZHANG Dong-mei Remote Sensing Technology Center Heilongjiang Academy of Agricultural Sciences Key Laboratory of Agricultural Remote Sensing Ministry of Agriculture/Institute of Agricultural Resources and Regional PlanningChinese Academy of Agricultural Sciences

Rice planting patterns have changed dramatically over the past several decades in northeast China （NEC） due to the combined influence of global change and agricultural policy. Except for its great implications for environmental protection and climate change adaption, the spatio-temporal changes of rice cultivation in NEC are not clear. In this study, we conducted spatio-temporal analyses of NEC＇s major rice production region, Heilongjiang Province, by using satellite-derived rice cultivation maps. We found that the total cultivated area of rice in Heilongjiang Province increased largely from 1993 to 2011 and it expanded spatially to the northern and eastern part of the Sanjiang Plain. The results also showed that rice cultivation areas experienced a larger increase in the region managed by the Reclamation Management Bureau （RMB） than that managed by the local provincial government. Rice cultivation changes were closely related with those geographic factors over the investigated periods, represented by the geomorphic （slope）, climatic （accumulated temperature）, and hydrological （watershed） variables. These findings provide clear evidence that crop cultivation in NEC has been modified to better cope with the global change.

关键词： paddy rice spatio-temporal change cultivation area geographical factors

晚中更新世以来武威盆地沉积特征——基于wv3钻孔的释光年代学研究

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地质论评 2024年第5期70卷 1689-1708页

作者：郭力菲潘宝林王均平程馨琳杨勇周锐刘秀英蔡卓昀首都师范大学资源环境与旅游学院释光断代实验室北京100048 中国地质科学院地质力学研究所北京100081 中国地震局地震预测研究所北京100036 泰山学院山东泰安271000

青藏高原东北缘河西走廊形成了一系列新生代盆地,是研究盆地沉积演化的重要区域。武威盆地位于河西走廊东部,盆地内沉积了较厚的新生代冲洪积地层。为了厘清武威盆地晚中更新世以来的沉积演化历史,笔者等在武威盆地石羊河中—上游处钻... 详细信息

青藏高原东北缘河西走廊形成了一系列新生代盆地,是研究盆地沉积演化的重要区域。武威盆地位于河西走廊东部,盆地内沉积了较厚的新生代冲洪积地层。为了厘清武威盆地晚中更新世以来的沉积演化历史,笔者等在武威盆地石羊河中—上游处钻取了长207 m的wv3钻孔岩芯,获得了上部17 m岩芯的19个钾长石两步法pIR200 IR290年龄和2个多步法MET-pIRIR年龄,结合粒度资料,重建了武威盆地石羊河流域中—下游晚中更新世以来的光释光年代学框架和沉积历史。结果表明:两步法pIR200 IR290和多步法MET-pIRIR年龄在误差范围内一致。220~128 ka时期,沉积速率最小,为0.35 mm/ka,水动力条件较强,以侵蚀为主;128~108 ka(MIS 5d、MIS 5e)时期沉积速率为1.94 mm/ka,沉积物粒径由粗变细,表明此时水动力条件由强变弱;末次冰盛期到全新世早期(19~9 ka)沉积速率为2.78 mm/ka,沉积物粒径较细,表明此时水动力条件较弱,沉积速率最大,沉积为主。该地区新构造运动比较活跃,在末次间冰期至末次冰盛期期间存在逆冲活动。该研究对于揭示晚中更新世以来祁连山东北部石羊河流域沉积演化特征具有重要意义。

关键词：晚中更新世武威盆地石羊河光释光测年沉积演化