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Intrauterine Infections and Birth Defects

Biomedical and Environmental Sciences 2004年第4期17卷 476-491页

作者： XIAO-YING ZHENG TING ZHANG YI-FEI WANG CHEN XU GONG CHEN ruo-lei xin JIA-PENG CHEN XU-MEI HU QING YANG xin-MING SONG LI-HUA PANG YING JI HONG-MEI SUN lei ZHANG JU-FEN LIU YAN-LING GUO YAN ZHANG Institute of Population Research／WHO Collaborating Centeron Reproductive Health and Population Science Beijing 100871China Department of Infection and Immunity Capitallnstimte of PediatricsBeijing 100020China Medical School of Shanghai Jiatong University No.1954Huashan RoadShanghai 200030China Department of Embryology the Second Medical UniversityNo.280Chongqing NanluShanghai 200025China

Intrauterine infection is an important cause of some birth defects worldwide. The most common pathogens include rubella virus, cytomegaloviurs, ureaplasma urealyticum, toxoplasma, etc. General information about these pathogens in epidemiology, consequence of birth defects, and the possible mechanisms in the progress of birth defects, and the interventions to prevent or treat these pathogens?infections are described. The infections caused by rubella virus, cytomegaloviurs, ureaplasma urealyticum, toxoplasma, etc. are common, yet they are proved to be fatal during the pregnant period, especially during the first trimester. These infections may cause sterility, abortion, stillbirth, low birth weight, and affect multiple organs that may induce loss of hearing and vision, even fetal deformity and the long-term effects. These pathogens?infections may influence the microenvironment of placenta, including levels of enzymes and cytokines, and affect chondriosome that may induce the progress of birth defect. Early diagnosis of infections during pregnancy should be strengthened. There are still many things to be settled, such as the molecular mechanisms of birth defects, the effective vaccines to certain pathogens. Birth defect researches in terms of etiology and the development of applicable and sensitive pathogen detection technology and methods are imperative.

关键词： Pregnancy Complications Infectious Pregnancy Outcome Abnormalities Animals Female Humans Infant Newborn Placenta Diseases Pregnancy Pregnancy Trimester First Research Support Non-U.S. Gov't Rubella Toxoplasma Ureaplasma urealyticum

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中世纪的修道院藏书及其社会作用

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图书馆论坛 2009年第1期29卷 153-155,F0003页

作者：雷若欣四川大学历史文化学院四川成都610064

中世纪时期,修道院在图书的收藏、保存和管理方面作出了很大贡献。修道院藏书与中世纪的社会生活、文化教育和社会变革等密切相关,修道院藏书研究也为后人了解修道院文化和当时社会发展提供了一个新的视角。

关键词：中世纪修道院图书

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Unusual Patterns of Neural Tube Defects in a High Risk Region of Northern China

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Biomedical and Environmental Sciences 2009年第4期22卷 340-344页

作者： GONG CHEN LI-JUN PEI JIAN HUANG xin-MING SONG LIANG-MING LIN XUE GU JIAN-xin WU FANG WANG JI-lei WU JIA-PENG CHEN JU-FEN LIU ruo-lei xin TING ZHANG XIAO-YING ZHENG Institute of Population Research Peking University Beijing 100871 China Institute of Nutrition and Food Safety Chinese Center for Disease Control and Prevention Beijing 100050 China Capital Institute of Pediatrics Beijing 100020 China

Objective To study the prevalence of different types of neural tube defects （NTDs） in Luliang Prefecture, Shanxi province, where the prevalence of NTDs is unusually high and the correlation between NTDs prevalence and patterns. Methods A surveillance population-based birth defects was performed in Luliang Prefecture, Shanxi province. Results The results of our study showed that the prevalence of NTDs was 2-fold higher in Luliang Prefecture than in other areas of Shanxi province. Unusual patterns of NTDs were found, however, multiple NTDs were relatively common in Luliang Prefecture, accounting for over 13% of all NTDs cases in China. Conclusion The prevalence of NTDs is associated with its patterns.

关键词： Neural tube defects Epidemiology Geographic variation

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论公共历史学教育与高校历史专业人才培养的新趋向

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巢湖学院学报 2010年第4期12卷 122-126页

作者：雷若欣巢湖学院历史旅游文化系安徽巢湖238000

公共历史学教育是美国20世纪70年代兴起的一种新的历史教育形式。它以不同于传统历史教育的理念和方法,突出了历史教育的实用性和跨学科性。自此,公共历史学教育不仅培养了能满足客户需要和适应实际操作的公共历史学家,而且,这些公共历... 详细信息

公共历史学教育是美国20世纪70年代兴起的一种新的历史教育形式。它以不同于传统历史教育的理念和方法,突出了历史教育的实用性和跨学科性。自此,公共历史学教育不仅培养了能满足客户需要和适应实际操作的公共历史学家,而且,这些公共历史学家更多地以自己的工作在学院和课堂外对社会公众进行潜移默化的历史教育。公共历史学教育为新时代的历史教育开辟了广阔的发展空间。

关键词：高校公共历史学教育传统历史学教育

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中国古代尼姑世俗心态分析

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南都学坛（南阳师范学院人文社会科学学报） 2006年第1期26卷 32-36页

作者：雷若欣巢湖学院历史系安徽巢湖238000

中国古代的尼姑,是一个带有强烈宗教韵味的特殊群体。但因置身世俗社会,她们的活动又被赋予了世俗特性。尼姑世俗心态表现为:把握参政时机,拓宽生财之道,创造灿烂文化,品味世俗情感等。

关键词：中国古代尼姑社会活动世俗性

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Correlation Between Birth Defects and Dietary Nutrition Status in a High Incidence Area of China

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Biomedical and Environmental Sciences 2008年第1期21卷 37-44页

作者： BAO-YUAN ZHANG TING ZHANG LIANG-MING LIN FANG WANG ruo-lei xin XUE GU YU-NA HE DONG-MEI YU PEI-ZHEN LI QING-SHAN ZHANG JIN ZHAO Yu-Fu QIN XIU-FENG YANG GONG CHEN JU-FEN LIU xin-MING SONG XIAO-YING ZHENG Capital Institute of Pediatrics Beijing 100020 China Chinese Center for Disease Control and Prevention Beijing 100050 China Department of Epidemiology Shanxi Medical University Taiyuan 030001 Shanxi China Center for Disease Control and Prevention of Shanxi Province Taiyuan 030012 Shanxi China xinzhou Center for Disease Control and Prevention Xinzhou 034000 Shanxi China WHO Collaborating Center for Research in Reproductive Health and Population Science Institute of Population Research Peking University Beijing 100871 China

Objective To investigate the association between birth defects and dietary nutrient intake in a high risk area of China. Methods A dietary survey was performed and serum folic acid was measured in women whose pregnancy was affected by neural tube defects （NTDs） or unaffected by any birth defects （BDs） in Zhongyang and Jiaokou Counties in Shanxi Province of China. ResuIts The local average consumption of foods including dark green vegetables, fruits, fat and meat, and nutrient intake （e.g. energy, protein, retinol, riboflavin, vitamin E, and selenium） were lower than the national average level. In women of childbearing age, these regions, the intake of nutrients was much lower than the recommended nutrient intake （9%-77%）. The case-control dietary nutrition study of women whose pregnancy was affected by BDs （including NTDs and congenital heart defects） demonstrated that, in early pregnancy, adequate nutrition （i.e. eating meat, fresh vegetables, fruit more than once a week） was a protective factor, while eating germinated potatoes was a risk factor. The geometrical mean （pS- p95） of serum folic acid in women with NTD birth defects was 9.6 nmol/L （3.6, 23.03）, which was significantly lower than that in normal women （14.03 nmol/L）. Conclusion Women of childbearing age in the two counties of Shanxi Province, China, have a marked insufficient intake of some nutrients, especially folic acid, zinc, vitamins A and B12. This nutrient deficiency may be an important risk factor for the high prevalence of birth defects in these regions. Therefore, adequate dietary nutrition in early pregnancy can prevent BDs.

关键词： Birth defects Dietary survey Folic acid Nutrition status

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浅析现代文化墙的由来、分类及功能

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张家口职业技术学院学报 2014年第4期27卷 60-63页

作者：雷若欣巢湖学院历史旅游文化系安徽巢湖238000

近年来,墙壁已成了城乡展示自身的重要窗口之一。在简单追溯文化墙历史由来的基础上,对文化墙的不同类型进行梳理,考察文化墙在美化城乡景观、加快信息传播和促进文化产业发展等方面的功能,以期为城乡文化墙的进一步发展和管理提供一些... 详细信息

近年来,墙壁已成了城乡展示自身的重要窗口之一。在简单追溯文化墙历史由来的基础上,对文化墙的不同类型进行梳理,考察文化墙在美化城乡景观、加快信息传播和促进文化产业发展等方面的功能,以期为城乡文化墙的进一步发展和管理提供一些理论依据。

关键词：文化墙由来类型功能

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“互联网+”背景下酒店专业英语能力培养——“多模态-多媒体-多环境”教学模式构建

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巢湖学院学报 2019年第2期21卷 139-144页

作者：吴萍雷若欣巢湖学院旅游管理学院

在互联网与信息技术迅速发展的背景下,“多模态-多媒体-多环境”教育环境已逐渐形成。将多模态、多媒体、多环境教学模式运用于酒店专业英语教学,利用互联网,通过多模态、多媒体、多环境教学输入——线上微课导学、线下翻转课堂、校内... 详细信息

在互联网与信息技术迅速发展的背景下,“多模态-多媒体-多环境”教育环境已逐渐形成。将多模态、多媒体、多环境教学模式运用于酒店专业英语教学,利用互联网,通过多模态、多媒体、多环境教学输入——线上微课导学、线下翻转课堂、校内实验室情景模拟实训、校外实习基地实景实训,以及多模态、多媒体、多环境教学输出——角色扮演、实训视频制作、课堂 PPT 展示、团队情景剧竞演,将学习模式从单一的课堂教学扩展开来,以多模态形式在多环境下引导学生构建知识体系,极大提升学生的职业英语水平与跨文化交际能力,满足酒店企业对专业人才的需求。

关键词：多模态教学多媒体教学多环境教学酒店专业英语能力

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Effectiveness of onsite and online education in enhancing knowledge and use of human immunodeficiency virus pre-and postexposure prophylaxis

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World Journal of Clinical Cases 2024年第22期12卷 5042-5050页

作者： Ying Shao Mei Zhang Li-Jun Sun Hong-Wei Zhang An Liu Xi Wang ruo-lei xin Jian-Wei Li Jiang-Zhu Ye Yue Gao Zhang-Li Wang Zai-Cun Li Tong Zhang Clinic of Center for Infection Beijing Youan HospitalCapital Medical UniversityBeijing 100069China Department of Infectious Diseases and Medical Immunology Beijing Youan HospitalCapital Medical UniversityBeijing 100069China Chinese Association of STD and AIDS Prevention and Control Beijing 100050China Institute of STD/AIDS Prevention and Control Beijing Center for Disease Prevention and ControlBeijing 100013China

BACKGROUND Enhancing awareness and use of pre-exposure prophylaxis(PrEP)and postexposure prophylaxis(PEP)is vital to curb human immunodeficiency virus(HIV)***-risk behaviors prevalent among sexually transmitted infection clinic outpatients underscore the need for increased PrEP/PEP education in this *** To investigate the effects of both onsite and online health education on the knowledge of,and willingness to use,PrEP and PEP among individuals receiving PEP *** Participants were drawn from a cohort study on PEP service intervention at an STD/AIDS outpatient clinic in designated HIV/AIDS hospitals in Beijing,conducted from January 1 to June 30,*** education was provided both onsite and online during *** assessing knowledge of,and willingness to use,PrEP/PEP were administered at baseline and again at 24 wk *** A total of 112 participants were enrolled in the study;105 completed the follow-up at week *** percentage of participants with adequate knowledge of,and willingness to use,PrEP significantly increased from 65.2%and 69.6%at baseline to 83.8%and 82.9%at the end of the intervention(both P<0.05).Similarly,those with adequate knowledge of,and willingness to use,PEP increased from 74.1%and 77.7%at baseline to 92.4%and 89.5%at week 24(P<0.05).Being between 31 years and 40 years of age,having a postgraduate degree or higher,and reporting a monthly expenditure of RMB 5000 or more were found to be significantly associated with knowledge of PrEP and PEP(both P<0.05).CONCLUSION The findings show that both onsite and online health education significantly improved the knowledge of,and increased willingness to use,PrEP and PEP in individuals utilizing PEP services.

关键词： Human immunodeficiency virus Pre-exposure prophylaxis Post-exposure prophylaxis Health education Intervention

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酒店管理专业中外合作办学教学模式对接

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渭南师范学院学报 2016年第22期31卷 25-32页

作者：吴萍曾静雷若欣巢湖学院旅游管理学院安徽巢湖238000

酒店管理专业中外合作办学以"3+1"嫁接型为主流,国内合作方院校目前均为地方应用型高校。国外酒店专业人才培养模式以"瑞士洛桑"与"美国康奈尔"模式为典型,我国则采用"平台+模块"模式。为了实现中外教学模式的对接,应兼顾中外双方,优化... 详细信息

酒店管理专业中外合作办学以"3+1"嫁接型为主流,国内合作方院校目前均为地方应用型高校。国外酒店专业人才培养模式以"瑞士洛桑"与"美国康奈尔"模式为典型,我国则采用"平台+模块"模式。为了实现中外教学模式的对接,应兼顾中外双方,优化课程设置,语言类课程与专业课程并重,开展渐进式双语教学,并将微课引入双语教学,以行业英语运用能力为准绳,建立中外融合型与连贯性强的课程体系结构;以就业能力培养为导向,构建层级递进式实践教学体系,将教学与考核融为一体,组织项目教学,实现课程模块间的联动;以"外语能力与实践能力"培养为主线,突出酒店管理专业人才培养模式的"国际型、应用型、创新型"。

关键词：中外合作办学酒店管理课程体系双语教学微课

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