Unusual Patterns of Neural Tube Defects in a High Risk Region of Northern China
Unusual Patterns of Neural Tube Defects in a High Risk Region of Northern China作者机构:Institute of Population Research Peking University Beijing 100871 China Institute of Nutrition and Food Safety Chinese Center for Disease Control and Prevention Beijing 100050 China Capital Institute of Pediatrics Beijing 100020 China
出 版 物:《Biomedical and Environmental Sciences》 (生物医学与环境科学(英文版))
年 卷 期:2009年第22卷第4期
页 面:340-344页
核心收录:
学科分类:1007[医学-药学(可授医学、理学学位)] 0830[工学-环境科学与工程(可授工学、理学、农学学位)] 100705[医学-微生物与生化药学] 1004[医学-公共卫生与预防医学(可授医学、理学学位)] 1001[医学-基础医学(可授医学、理学学位)] 100103[医学-病原生物学] 10[医学]
基 金:supported by the Major State Basic Research and Development Program of China "973 Program" (No.2007CB511901) special for National Postdoctoral fund (200801016) National Health Baby Promotion Program (No. FP2000NO13) Education Ministry Key Program (No. 02185) National Yangzi Scholar Program, 211 and 985 Projects of Peking University (No. 20020903)
主 题:Neural tube defects Epidemiology Geographic variation
摘 要:Objective To study the prevalence of different types of neural tube defects (NTDs) in Luliang Prefecture, Shanxi province, where the prevalence of NTDs is unusually high and the correlation between NTDs prevalence and patterns. Methods A surveillance population-based birth defects was performed in Luliang Prefecture, Shanxi province. Results The results of our study showed that the prevalence of NTDs was 2-fold higher in Luliang Prefecture than in other areas of Shanxi province. Unusual patterns of NTDs were found, however, multiple NTDs were relatively common in Luliang Prefecture, accounting for over 13% of all NTDs cases in China. Conclusion The prevalence of NTDs is associated with its patterns.