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SoySNP618K array:A high-resolution single nucleotide polymorphism platform as a valuable genomic resource for soybean genetics and breeding

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Journal of Integrative Plant Biology 2022年第3期64卷 632-648页

作者： Yan-Fei Li Ying-Hui Li Shan-Shan Su Jochen CReif Zhao-Ming Qi Xiao-Bo Wang Xing Wang Yu Tian De-Lin Li ru-jian sun Zhang-Xiong Liu Ze-Jun Xu Guang-Hui Fu Ya-Liang Ji Qing-Shan Chen Ji-Qiang Liu Li-Juan Qiu The National Key Facility for Crop Gene Resources and Genetic Improvement(NFCRI)/Key Laboratory of Crop Gene Resource andGermplasm Enhancement(MOA)/Key Laboratory of Soybean Biology(Beijing)(MOA) Institute of Crop SciencesChinese Academy ofAgricultural SciencesBeijing 100081China Beijing Compass Biotechnology Co.Ltd Beijing 102206China Department of Breeding Research Leibniz Institute of Plant Genetics and Crop Plant Research(IPK)Gatersleben 06466Germany Key Laboratory of Soybean Biology in Chinese Ministry of Education(Key Laboratory of Soybean Biology and Breeding/Genetics ofChinese Agriculture Ministry) Northeast Agricultural UniversityHarbin 150030China School of Agronomy Anhui Agricultural UniversityHefei 230036China Xuzhou Institute of Agricultural Sciences of Xu-huai Region of jiangsu Xuzhou 221131China Department of Plant Genetics and Breeding China Agricultural UniversityBeijing 100193China Hulun Buir Institution of Agricultural Sciences ZhalantunInner Mongolia 021000China Suzhou Academy of Agricultural Sciences Suzhou 234000China

Innovations in genomics have enabled the development of low-cost,high-resolution,single nucleotide polymorphism(SNP)genotyping arrays that accelerate breeding progress and support basic research in crop ***,we developed and validated the Soy SNP618 K array(618,888 SNPs)for the important crop *** SNPs were selected from whole-genome resequencing data containing 2,214 diverse soybean accessions;29.34%of the SNPs mapped to genic regions representing 86.85%of the 56,044annotated high-confidence ***-by-state analyses of 318 soybeans revealed 17 redundant accessions,highlighting the potential of the Soy SNP618 K array in supporting gene bank *** patterns of population stratification and genomic regions enriched through domestication were highly consistent with previous findings based on resequencing data,suggesting that the ascertainment bias in the Soy SNP618 K array was largely compensated ***-wide association mapping in combination with reported quantitative trait loci enabled fine-mapping of genes known to influence flowering time,E2 and Gm PRR3 b,and of a new candidate gene,Gm ***,genomic prediction of flowering and maturity time in 502 recombinant inbred lines was highly accurate(>0.65).Thus,the Soy SNP618 K array is a valuable genomic tool that can be used to address many questions in applied breeding,germplasm management,and basic crop research.

关键词： functional single nucleotide polymorphism array gene discovery genomic selection genome-wide association studies marker-assisted selection soybean

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Brain endothelial cyclic GMP-AMP synthase(cGAS)-stimulator of interferon genes(STING)signaling pathway in aging and neurodegeneration

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Neural Regeneration Research 2025年第7期20卷 2005-2007页

作者： Bryan sun Lulin Li jian Luo Palo Alto Veterans Institute for Research VA Palo Alto Health Care SystemPalo AltoCAUSA Polytrauma System of Care VA Palo Alto Health Care SystemPalo AltoCAUSA

The cyclic GMP-AMP synthase(cGAS)-stimulator of interferon genes(STING)signaling pathway has emerged as a key mediator of *** current studies primarily attribute its effects to neurons and glial cells,emerging research suggests that cGAS-STING signaling may play a critical role in cerebral vasculature,particularly in brain endothelial ***,studying the role 7of inflammation caused by the cGAS-STING pathway in brain endothelial cells could provide a more comprehensive understanding of neuroinflammatory disease and new avenues for therapeutic ***,we review the multifaceted role of global cGAS-STING signaling in various neurological and neuroinflammatory diseases and the potential contribution of cGAS-STING in brain endothelial cells.

关键词： stimulator interferon inflammation

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Construction of Ni single-atom coordinated with doped N and S elements for mild hydrogenation of methyl acrylate to methyl propionate

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Nano Research 2025年第1期18卷 217-224页

作者： Taolue sun Chen jian Gang Wang Hui Zhao Guoliang Zhang Zengxi Li Chunshan Li State Key Laboratory of Mesoscience and Engineering CAS Key Laboratory of Green Process and EngineeringBeijing Key Laboratory of Ionic Liquids Clean ProcessInstitute of Process EngineeringChinese Academy of SciencesBeijing 100190China School of Chemical Engineering University of Chinese Academy of SciencesBeijing 100049China Huizhou Institute of Green Energy and Advanced Materials Huizhou 516081China Advanced Energy Science and Technology Guangdong Laboratory Huizhou 516081China

Although the nickel-based catalyst is able toexhibit comparative catalytic activity to noble metal formethyl acrylate hydrogenation,it requires strict reactioncondition,which can be improved by regulation ofcoordination *** this study,we constructed akind of Ni single-atom coordinated with N and S(Ni-NSC)through the pyrolysis of organic Ni-based precursors at600℃.The existence and fine structure of Ni single-atom were confirmed by the spherical electron microscopicobservation in combination with the X-ray absorption spectroscopy(XAS)*** addition,the catalytichydrogenation assessment suggested that the as-prepared Ni-NSC catalyst exhibited higher activity and stability than theNi/NSC supported catalyst prepared by incipient wetness impregnation *** remarkable catalytic activity was dueto the high dispersion and density of Ni single-atom and weak adsorption energy of intermediates on these Ni sites.

关键词： methyl acrylate mild hydrogenation Ni single-atom coordination environment adsorption energy

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新质生产力的运行机理、生成逻辑与模式建构——基于生产力与生产关系辩证统一的视角

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新疆师范大学学报（哲学社会科学版） 2025年第1期46卷 89-97页

作者：李勇坚张海汝中国社会科学院财经战略研究院北京100005 浙江财经大学浙江杭州310018 江苏省社会科学院经济研究所江苏南京210004

新质生产力是创新发挥主导作用,摆脱传统经济增长方式、生产力发展路径,具有高科技、高效能、高质量特征,符合新发展理念的先进生产力质态。纵观三次科技革命变革生产力的历程,新质生产力的产生和发展是生产力与生产关系相互作用的结果... 详细信息

新质生产力是创新发挥主导作用,摆脱传统经济增长方式、生产力发展路径,具有高科技、高效能、高质量特征,符合新发展理念的先进生产力质态。纵观三次科技革命变革生产力的历程,新质生产力的产生和发展是生产力与生产关系相互作用的结果,具有生产力与生产关系的双重内涵和发展要求。新质生产力以新型劳动者、新型劳动资料、新型劳动对象及其组合模式和新型生产关系为架构要素与发展基础,其生成逻辑与运行机理是由技术革命性突破引发,在催生新型生产力要素、新型要素组合模式的基础上促使与新质生产力相适应的新型生产关系变革形成,新型生产关系的反作用促进新质生产力进一步生成的过程。发展新质生产力要以实施创新驱动战略、加快产业深度转型、构建要素生态系统和全面深化改革为基本模式和关键路径。亟须加快实现高水平科技自立自强,加快技术革命性创新;促进产业深度转型,构建现代化产业体系;促进生产要素创新配置,构建新质生产要素系统;全面深化改革,加快建立健全与新质生产力相适应的新型生产关系,促进新质生产力加快形成发展。

关键词：新质生产力新型生产关系技术革命性突破全面深化改革

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Recent Advances in Fibrous Materials for Hydroelectricity Generation

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Nano-Micro Letters 2025年第2期17卷 109-133页

作者： Can Ge Duo Xu Xiao Feng Xing Yang Zheheng Song Yuhang Song Jingyu Chen Yingcun Liu Chong Gao Yong Du Zhe sun Weilin Xu jian Fang College of Textile and Clothing Engineering Soochow UniversitySuzhou 215123People’s Republic of China National Engineering Laboratory for Modern Silk Soochow UniversitySuzhou 215123People’s Republic of China State Key Laboratory of New Textile Materials and Advanced Processing Technologies Wuhan Textile UniversityWuhan 430200People’s Republic of China Institute of Functional Nano&Soft Materials(FUNSOM) Soochow UniversitySuzhou 215123People’s Republic of China Department of Electrical and Computer Engineering University of MassachusettsAmherstMA 01003USA Department of Materials Imperial College LondonSouth Kensington CampusLondon SW72AZUK College of Textile Science and Engineering Zhejiang Sci-Tech UniversityHangzhou 310018People’s Republic of China School of Materials Science and Engineering Shanghai Institute of Technology100 Haiquan RoadShanghai 201418People’s Republic of China

Depleting fossil energy sources and conventional polluting power generation pose a threat to sustainable *** generation from ubiquitous and spontaneous phase transitions between liquid and gaseous water has been considered a promising strategy for mitigating the energy *** materials with unique flexibility,processability,multifunctionality,and practicability have been widely applied for fibrous materials-based hydroelectricity generation(FHG).In this review,the power generation mechanisms,design principles,and electricity enhancement factors of FHG are first ***,the fabrication strategies and characteristics of varied constructions including 1D fiber,1D yarn,2D fabric,2D membrane,3D fibrous framework,and 3D fibrous gel are ***,the advanced functions of FHG during water harvesting,proton dissociation,ion separation,and charge accumulation processes are analyzed in ***,the potential applications including power supply,energy storage,electrical sensor,and information expression are also ***,some existing challenges are considered and prospects for future development are sincerely proposed.

关键词： Hydroelectricity Fibrous material Streaming potential Ion diffusion

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miRNA-21-5p is an important contributor to the promotion of injured peripheral nerve regeneration using hypoxia-pretreated bone marrow-derived neural crest cells

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Neural Regeneration Research 2025年第1期20卷 277-290页

作者： Meng Cong Jing-Jing Hu Yan Yu Xiao-Li Li Xiao-Ting sun Li-Ting Wang Xia Wu Ling-Jie Zhu Xiao-Jia Yang Qian-ru He Fei Ding Hai-Yan Shi School of Medicine Nantong UniversityNantongJiangsu ProvinceChina Key Laboratory of Neuroregeneration of jiangsu and Ministry of Education and Coinnovation Center of Neuroregeneration Nantong UniversityNantongJiangsu ProvinceChina Department of Physiology Jiangsu Health Vocational CollegeNanjingJiangsu ProvinceChina Department of Pathology Affiliated Hospital of Nantong UniversityNantongJiangsu ProvinceChina jiangsu Clinical Medicine Center of Tissue Engineering and Nerve Injury Repair Affiliated Hospital of Nantong UniversityNantongJiangsu ProvinceChina

Our previous study found that rat bone marrow–derived neural crest cells(acting as Schwann cell progenitors)have the potential to promote long-distance nerve ***-based therapy can enhance peripheral nerve repair and regeneration through paracrine bioactive factors and intercellular ***,the complex contributions of various types of soluble cytokines and extracellular vesicle cargos to the secretome remain *** investigate the role of the secretome and extracellular vesicles in repairing damaged peripheral nerves,we collected conditioned culture medium from hypoxia-pretreated neural crest cells,and found that it significantly promoted the repair of sensory neurons damaged by oxygen-glucose *** mRNA expression of trophic factors was highly expressed in hypoxia-pretreated neural crest *** performed RNA sequencing and bioinformatics analysis and found that miR-21-5p was enriched in hypoxia-pretreated extracellular vesicles of neural crest ***,to further clarify the role of hypoxia-pretreated neural crest cell extracellular vesicles rich in miR-21-5p in axonal growth and regeneration of sensory neurons,we used a microfluidic axonal dissociation model of sensory neurons in vitro,and found that hypoxia-pretreated neural crest cell extracellular vesicles promoted axonal growth and regeneration of sensory neurons,which was greatly dependent on loaded ***,we constructed a miR-21-5p-loaded neural conduit to repair the sciatic nerve defect in rats and found that the motor and sensory functions of injured rat hind limb,as well as muscle tissue morphology of the hind limbs,were obviously *** findings suggest that hypoxia-pretreated neural crest extracellular vesicles are natural nanoparticles rich in ***-21-5p is one of the main contributors to promoting nerve regeneration by the neural crest cell *** helps to explain the mechanism of action of the secretome and e

关键词： axotomy cell-free therapy conditioned medium extracellular vesicles hypoxic preconditioning microRNA oxygen-glucose deprivation peripheral nerve injury Schwann cell precursors

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A Review on Crystalline Porous MOFs Materials in Photocatalytic Transformations of Organic Compounds in Recent Three Years

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Chinese Journal of Structural Chemistry 2022年第11期41卷 71-83页

作者： Hao Zhang ru sun Da-Cheng Li jian-Min Dou Shandong Provincial Key Laboratory of Chemical Energy Storage and Novel Cell Technology School of Chemistry and Chemical EngineeringLiaocheng UniversityShandong 252059China

Metal-organic frameworks(MOFs)have always been the focus of chemists due to their diverse structures,adjustable pore size and high stability since they came into *** recent years,as one of the most significant applications of MOFs porous materials,photocatalytic organic compounds transformation has made full-grown progress both in the preparation of the catalysts themselves and in the scope of specific ***,we summarize the research progress of MOFs catalysts for photocatalytic transformations of organic compounds in recent three *** outstanding works on the preparation and synthesis strategies of photocatalysts are introduced firstly,including internal optimization and modification of MOFs,POM@MOF composite and core-shell MOF@COF *** second part is about the application of diverse types of organic reactions,including dual-function organic reactions,catalytic oxidation reactions,comprehensive utilization of CO_(2) and degradation of organic ***,the development opportunities and some problems to be solved in this field are proposed.

关键词： metal-organic frameworks porous materials photocatalytic reaction organic transformations

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MECHANICAL PROPERTIES AND CURING KINETICS OF EPOXY RESINS CURED BY VARIOUS AMINO-TERMINATED POLYETHERS

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Chinese Journal of Polymer Science 2010年第6期28卷 961-969页

作者： Li-ying Zhao jian-guo Guan Hui-ru Ma Zhi-gang sun State Key Laboratory of Advanced Technology for Materials Synthesis and Processing Wuhan University of TechnologyWuhan 430070China

A high performance thermosetting epoxy resin crosslinkable at room temperature was obtained via directly moulding diglycidyl ether of bisphenol A（DGEBA） and flexibleα,ω-bisamino（n-alkylene）phenyl terminated poly（ethylene glycol）.The influences of the n-alkylene inserted in aminophenyl of flexible amino-terminated polythers（ATPE） on the mechanical properties,fractographs and curing kinetics of the ATPE-DGEBA cured products were *** results show that the insertion of n-alkylene group into the aminophenyl group of the ATPE,on one hand,can significantly increase the strain relaxation rate and decrease glass transition temperature of the ATPE-DGEBA cured products,resulting in slight decrease of the Young’s modulus and tensile strength,and significant increase of the toughness and elongation of the ATPE-DGEBA cured *** the other hand,it can remarkably enhance the reactivity of amine with epoxy,much accelerating the curing rate of the ATPE-DGEBA *** activation energy of DGEBA cured by BAPTPE,BAMPTPE and BAEPTPE was 53.1,28.5 and 25.4 kJ·mol;,*** as-obtained ATPE-DGEBA cured products are homogeneous, transparent,and show excellent mechanical properties including tensile strength and *** they are promising to have important applications in structure adhesives,casting bulk materials,functional coatings,cryogenic engineering, damping and sound absorbing materials.

关键词： Epoxy resin Amine-terminated polyether Fractography Curing kinetics Mechanical properties

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Novel congestion control approach in wireless multimedia sensor networks

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The Journal of China Universities of Posts and Telecommunications 2011年第2期18卷 1-8页

作者： LIN Qiao-min WANG ru-chuan GUO jian sun Li-juan College of Computer Nanjing University of Posts and Telecommunications Nanjing 210003 China State Key-lab for Novel Software Technology Nanjing University Nanjing 210093 China

Data generated in wireless multimedia sensor networks （WMSNs） may have different importance and it has been claimed that the network exert more efforts in servicing applications carrying more important information. Nevertheless, importance of packets cannot generally be accurately represented by a static priority value. This article presents a dynamic priority based congestion control （DPCC） approach that makes two major innovations in WMSNs. First, DPCC employs dynamic priority to represent packet importance. Second, it prioritizes the local traffic of motes near the base station when WMSN is highly congested. Simulation results confirm the superior performance of the proposed approach with respect to energy efficiency, loss probability and latency as well.

关键词： wireless multimedia sensor network congestion control quality of service (QoS) dynamic priority

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Synthesis, Crystal Structure and Theoretical Calculations of a New Co(Ⅱ) Coordination Polymer Based on 5-Nitroisophthalic Acid and Bis(imidazol) Ligands

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Chinese Journal of Structural Chemistry 2016年第2期35卷 298-306页

作者： LI Xiu-Mei sun Ming PAN Ya-ru JI jian-Ye Faculty of Chemistry Tonghua Normal University College of Plant Science Jilin Agriculture Science and Technology College

A new complex[Co（NIPH）（mbix）]n（1,H2NIPH = 5-nitroisophthalic acid,mbix =l,3-bis（imidazol-l-ylmethyl）benzene） has been hydrothermally synthesized and structurally characterized by elemental analysis,IR spectrum,UV spectrum,TG and single-crystal X-ray *** crystals crystallize in the triclinic system,space group P1 with a = 8.3797（8）,b= 10.2522（10）,c= 13.4244（13） A,α=94.820（2）,β=108.105（2）,γ=104.816（2）°,V=1042.84（17） A^3,C（22）H（17）CoN5O6,Mr = 506.34,Dc = 1.613 g/cm^3,F（000） = 518,Z = 2,μ（MoKα） =0.876 mm^（-1）,the final R = 0.0505 and wR = 0.1254 for 3267 observed reflections（I〉2σ（I））.The structure of 1 exhibits a two-dimensional network structure and is extended into a three-dimensional supramolecule through hydrogen bonds and n-n *** addition,Natural Bond Orbital（NBO） analysis was performed by using the PBE0/LANL2 DZ method built in Gaussian 09 *** calculation results showed obvious covalent interactions between the coordinated atoms and Co（Ⅱ） ion.

关键词： hydrothermal synthesis crystal structure cobalt complex natural bond orbital

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