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Obesity and bariatric surgery in kidney transplantation:A clinical review

World Journal of Diabetes 2021年第9期12卷 1563-1575页

作者： Massimiliano Veroux Edoardo Mattone Matteo Cavallo rossella gioco Daniela Corona Alessio Volpicelli Pierfrancesco Veroux Department of Medical and Surgical Sciences and Advanced Technologies GF Ingrassia University of CataniaCatania 95123Italy Vascular Surgery and Organ Transplant Unit University Hospital of CataniaCatania 95123Italy General Surgery Unit University Hospital of CataniaCatania 95123Italy Department of General Surgery and Medical Specialities University of CataniaCatania 95123Italy

Obesity is increasing worldwide,and this has major implications in the setting of kidney *** with obesity may have limited access to transplantation and increased posttransplant morbidity and *** transplant centers incorporate interventions aiming to target obesity in kidney transplant candidates,including dietary education and lifestyle *** those failing nutritional restriction and medical therapy,the use of bariatric surgery may increase the transplant candidacy of patients with obesity and endstage renal disease(ESRD)and may potentially improve the immediate and late *** surgery in ESRD patients is associated with weight loss ranging from 29.8% to 72.8% excess weight loss,with reported mortality and morbidity rates of 2% and 7%,*** most commonly performed bariatric surgical procedures in patients with ESRD and in transplant patients are laparoscopic sleeve gastrectomy(LSG)and laparoscopic Roux-en-Y gastric ***,the correct timing of bariatric surgery and the ideal type of surgery have yet to be determined,although pretransplant LSG seems to be associated with an acceptable risk-benefit *** review the impact of obesity on kidney transplant candidates and recipients and in potential living kidney donors,exploring the potential impact of bariatric surgery in addressing obesity in these populations,thereby potentially improving posttransplant outcomes.

关键词： End-stage renal disease Living donor Gastric bypass Sleeve gastrectomy Waiting list Deceased donor

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Gastrointestinal complications after kidney transplantation

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World Journal of Gastroenterology 2020年第38期26卷 5797-5811页

作者： rossella gioco Daniela Corona Burcin Ekser Lidia Puzzo Gaetano Inserra Flavia Pinto Chiara Schipa Francesca Privitera Pierfrancesco Veroux Massimiliano Veroux General Surgery Unit University Hospital of CataniaCatania 95123Italy Department of Biomedical and Biotechnological Sciences University of CataniaCatania 95123Italy Department of Surgery Indiana University School of MedicineIndianapolisIN 46202United States Pathology Unit Department of Medical and Surgical Sciences and Advanced TechnologiesUniversity of CataniaCatania 95123Italy Gastroenterology Unit Department of Clinical and Experimental MedicineUniversity of CataniaCatania 95100Italy Organ Transplant Unit University Hospital of CataniaCatania 95123Italy General Surgery Unit Organ Transplant UnitUniversity Hospital of CataniaCatania 95123Italy Department of Medical and Surgical Sciences and Advanced Technologies University Hospital of CataniaCatania 95123Italy

Gastrointestinal complications are common after renal transplantation,and they have a wide clinical spectrum,varying from diarrhoea to post-transplant inflammatory bowel disease(IBD).Chronic immunosuppression may increase the risk of post-transplant infection and medication-related injury and may also be responsible for IBD in kidney transplant re-cipients despite *** the various forms of post-transplant colitis is challenging,since most have similar clinical and histological ***-related colitis are the most frequently encountered colitis after kidney transplantation,particularly those related to the chronic use of mycophenolate mofetil,while de novo IBDs are quite *** review will explore colitis after kidney transplantation,with a particular focus on different clinical and histological features,attempting to clearly identify the right treatment,thereby improving the final outcome of patients.

关键词： Inflammatory bowel disease Kidney transplantation Solid organ transplantation Crohn disease Ulcerative colitis Mycophenolate mofetil colitis Mycophenolate mofetil Colitis Cytomegalovirus

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