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一个新发现的患利德尔综合征家庭中,患者呈现似原发性高血压的临床表型

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中华高血压杂志 2012年第2期20卷 198-198页

作者： Ermanno Rossi Enrico Farnetti Davide Nicoli Marco Sazzini Franco Perazzoli Giuseppe Regolisti Chiara Grasselli rosaria santi Aurelio Negro Vincenzo Mazzeo Franco Mantero Donata Luiselli Bruno Casali 罗冬梅叶鹏

利德尔综合征（Liddle’s syndrome，LS）是一个拟似盐皮质激素过多的，由单基因异常造成的，表现为血压升高的综合征。目前在年轻低钾性高血压患者的鉴别诊断中考虑该疾病的存在。该研究的目的是：①评估一个新近发现的来自意大利西西... 详细信息

利德尔综合征（Liddle’s syndrome，LS）是一个拟似盐皮质激素过多的，由单基因异常造成的，表现为血压升高的综合征。目前在年轻低钾性高血压患者的鉴别诊断中考虑该疾病的存在。该研究的目的是：①评估一个新近发现的来自意大利西西里地区携带上皮钠通道P617L功能增强性13亚基的家族的临床表型。该研究组曾经报道在一个与新发现无关的西西里患者中存在这种基因突变并表现包括低血钾的典型LS症状。②确定新发现的家庭和先前发现家庭是否存在一种尚未明确的生物关系。

关键词：高血压患者临床表型综合征原发性高血压家庭盐皮质激素上皮钠通道基因异常

Potential application of the Kampo medicine goshajinkigan for prevention of chemotherapy-induced peripheral neuropathy

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Journal of Integrative Medicine 2017年第2期15卷 77-87页

作者： Marco Cascella Maria rosaria Muzio Division of Anesthesia Department of Anesthesia and Pain Medicine Istituto Nazionale Tumori "Fondazione G. Pascale"--IRCCS via Mariano Semmola Naples 80131 Italy Division of Infantile Neuropsychiatry UOMI-Maternal and Infant Health Asl NA 3 SUD Torre del Greco via Marconi Naples 80059 Italy

Chemotherapy-induced peripheral neuropathy （CIPN） is one of the most common and severe adverse effects related to cancer treatment. Unfortunately, although several agents and protocols have been proposed, no prophylactic strategies have yet to be proven useful. Therefore, new alternative therapies have been considered for CIPN prevention. Herbal medicine in Japan, called Kampo medicine, is derived from traditional Chinese medicine. Goshajinkigan （GJG） is a Kampo medicine, that is comprised of ten herbs. The aim of this work is to analyse the results of pre-clinical and clinical studies on the potential applications of GJG in CIPN prevention.

关键词： chemotherapy peripheral neuropathies herbal medicine alternative medicine natural products

Heterogeneous catalysis under flow for the 21st century fine chemical industry

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Green Energy & Environment 2021年第2期6卷 161-166页

作者： rosaria Ciriminna Mario Pagliaro Rafael Luque Istituto per Io Studio dei Mate riali Nanostnuturati CNRwia U.La Malfa 15390146PulemoItaly Deparamento de Quimica Orginica Univeridad de CordobaCampus de RabonalesEdificio Marie Curie(C-3)Cra Nnal IV-Akm 396Cordoba14014Spain Peoples Friendship University of Russia(RUDN Universiy) 6 Miklukho Maklaya St117198MoscowRussia

Due to metal leaching and poor catalyst stability, the chemical industry's fine chemical and pharmaceutical sectors have been historically reluctant to use supported transition metal catalysts to manufacture fine chemicals and active pharmaceutical ingredients. With the advent of new generation supported metal catalysts and flow chemistry, we argue in this study, this situation is poised to quickly change. Alongside heterogenized metal nanoparticles, both single-site molecular and single-atom catalyst will become ubiquitous. This study offers a critical outlook taking into account both technical and economic aspects.

关键词： Fine chemical Heterogeneous catalysis Single atom catalysis Green chemistry Chemical industry

Groups with Cyclic Outer Automizers

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Algebra Colloquium 2014年第3期21卷 381-398页

作者： Maria rosaria Celentani Giovanni Cutolo Antonella Leone Dipartimento di Matematica e Applieazioni 'R .Caccioppoli' Universita degli Studi di Napoli 'Federico II' Via Cintia Monte S. Angelo 1-80126 Napoli Italy

We consider groups G such that NG（H）/HCG（H） is cyclic for all H ≤ G. More specifically, we characterise locally nilpotent and supersoluble groups with this property.

关键词： automizers locally nilpotent supersoluble soluble groups

Size contrast of Pt nanoparticles formed on neighboring domains within suspended and supported graphene

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Nano Research 2018年第3期11卷 1589-1598页

作者： Dario Roccella Matteo Amati Hikmet Sezen rosaria Brescia Luca Gregoratti Universita degli Studi di Genova - Facolta di Scienze Matematiche Fisiche e Naturali Viale Benedetto XV Genova 3-16132 Italy Elettra - Sincrotrone Trieste S.C.p.A. in Area Science Park SS 14-Km 163.5 Trieste 34149 Italy Electron Microscopy Facility Istituto Italiano di Tecnologia (liT) via Morego 30 Genova 16163 Italy

The relatively small size of thin （one or few layers） graphene flakes makes it extremely difficult to study the behavior of suspended graphene by characterization techniques other than the electron microscopies. Herein, we exploited the capability of spatially resolved photoemission in combination with high resolution transmission electron microscopy to investigate the interaction of thermally evaporated Pt atoms on suspended and supported graphene. Spectroscopic and microscopic analyses reveal that the nucleation of nanometer- sized Pt particles in these two regions exhibit different trends. While only small nanometer-sized islands are present on the supported graphene, relatively larger clusters of islands were also found on the suspended flakes. The X-ray photoemission C ls core levels acquired after the Pt deposition show an increase in the number of vacancies in the graphene sheets.

关键词： graphene X-ray photoemissionspectroscopy scanning photoelectron microscop nanoparticles platinum suspended films

Ferrofluid measurements of bottom velocities and shear stresses

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Journal of Hydrodynamics 2015年第1期27卷 150-158页

作者： MUSUMECI rosaria E. MARLETTA Vincenzo ANDò Bruno BAGLIO Salvatore FOTI Enrico Department of Civil Engineering and Architecture University of Catania Department of Electric Electronic and Computer Science Engineering University of Catania

A novel direct measurement strategy of bottom velocities and shear stresses based on the use of ferrofluids is presented. Such a strategy overcomes some of the limits of state-of-the-art instruments. A preliminary experimental campaign has been carried out in the presence of currents in steady flow conditions in order to test the effects of ferrofluid quantity and of the controlling permanent magnetic force. An alternating current （AC） circuit and a direct current （DC） conditioning circuit have been tested. For velocities larger than 0.05 m/s, the near-bottom velocity-output voltage calibration curve has a monotone parabolic shape. The sensitivity of the instrument is increased by a factor of 30 when the DC circuit is used.

关键词： magnetofluids Rosensweig effect flow resistances bed shear stresses bottom velocities

The Recent Uses of Sol-Gel Doped Catalysts in Fine Chemistry

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复旦学报（自然科学版） 2005年第5期44卷 760-761页

作者： Mario Pagliaro rosaria Ciriminna Istituto per lo Studio dei Materiali Nanostrutturati CNR via Ugo La Malfa 153 90146 Palermo ItalyIstituto per lo Studio dei Materiali Nanostrutturati CNR via Ugo La Malfa 153 90146 Palermo Italy

A variety of sol-gel entrapped catalysts is available on the chemical market due to the unique advantages offered by these highly porous oxides doped with transition metal catalyst, enzymes or even living cells[1].Catalytic sol-gel lipase immobilizates were rapidly commercialized by Fluka after their invention by Reetz and coworkers in 1995 and have now reached a 2nd generation level of performance[2]. Besides esterification reactions these materials are also excellent catalysts in the kinetic resolution of chiral alcohols and amines, and are recyclable without any substantial loss in enantioselectivity (residual activity of 70% even after 20 reaction cycles).

关键词：溶胶凝胶体生物催化处理 CACHy 催化剂脂肪酶

Neurological diseases associated with autoantibodies targeting the voltage-gated potassium channel complex:immunobiology and clinical characteristics

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Neuroimmunology and Neuroinflammation 2016年第1期3卷 69-78页

作者： Domenico Plantone rosaria Renna Tatiana Koudriavtseva Multiple Sclerosis Center Unit of NeurologyRegina Elena National Cancer Institute00144 RomeItaly

Voltage-gated potassium channels(VGKCs)represent a group of tetrameric signaling proteins with several functions,including modulation of neuronal excitability and neurotransmitter ***,VGKCs give a key contribution to the generation of the action *** are complexed with other neuronal proteins,and it is now widely known that serum autoantibodies directed against VGKCs are actually directed against the potassium channel subunits only in a minority of *** contrast,these autoantibodies more commonly target three proteins that are complexed with alpha-dendrotoxin-labeled potassium channels in brain *** three proteins are contactin-associated protein-2(Caspr-2),leucine-rich,glioma inactivated 1(LGI-1)protein and the protein Tag-1/*** are detected only in a minority of seropositive patients for VGKC complex-IgG and do not significantly associate with Caspr-2 or *** all the cancers described in association with VGKC complex-IgG,lung carcinoma,thymoma,and hematologic malignancies are the most commonly *** will review all the major neurological conditions associated with VGKC *** include Isaacs’syndrome,Morvan syndrome,limbic encephalitis,facio-brachial dystonic seizures,chorea and other movement disorders,epilepsy,psychosis,gastrointestinal neuromuscular diseases,a subacute encephalopathy that mimics Creutzfeldt-Jakob prion disease both clinically and radiologically and autoimmune chronic *** vast majority of these conditions are reversible by immunotherapy,and it is becoming increasingly recognized that early diagnosis and detection of VGKC complex-IgG is critical in order to rapidly start the *** a result,VGKC complex-IgG are now part of the investigation of patients with unexplained subacute onset of epilepsy,memory or cognitive problems,or peripheral nerve hyperexcitability syndromes.

关键词： Chronic pain,epilepsy facio-brachial dystonic seizures leucine-rich glioma inactivated 1 protein limbic encephalitis movement disorders neuromyotonia voltage-gated potassium channels

Chestnut tannin:New use,research and bioeconomy

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Journal of Bioresources and Bioproducts 2024年第3期9卷 246-252页

作者： rosaria Ciriminna Francesco Meneguzzo Giovanna Li Petri Cosimo Meneguzzo Giuseppe Angellotti Mario Pagliaro Istituto per lo Studio dei Materiali Nanostrutturati CNRvia U.La Malfa 15390146 PalermoItaly Istituto per la Bioeconomia CNRvia Madonna del Piano 1050019 Sesto Fiorentino(FI)Italy HyRes Srl via Salvator Rosa 1882100 BeneventoItaly

Chestnut tannin,extracted from the bark or wood of chestnut trees,possesses unique properties that make it valuable in various *** serves as a natural source of tannins,which are widely used in the production of leather,textiles,and wood *** research continues to explore its potential applications,chestnut tannin remains a promising resource with diverse industrial *** new use,research and bioeconomy aspects,this study provides a unified perspective on chestnut *** advanced applications will likely emerge shortly.

关键词： Tannin Chestnut Bioeconomy Tannin market Hydrolysable tannin