Severe Ectopic Cushing’s Syndrome Due to ACTH-Secreting Pheochromocytoma
Severe Ectopic Cushing’s Syndrome Due to ACTH-Secreting Pheochromocytoma作者机构：Diabetologic Unit Arcispedale Santa Maria Nuova Reggio Emilia Italy Pathology Unit Arcispedale Santa Maria Nuova Reggio Emilia Italy Radiology Unit Arcispedale Santa Maria Nuova Reggio Emilia Italy Second Division of Internal Medicine and Hypertension Unit Arcispedale Santa Maria Nuova Reggio Emilia Italy
出 版 物：《International Journal of Clinical Medicine》 (临床医学国际期刊（英文）)
年 卷 期：2013年第4卷第4期
页 面：228-231页
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
主 题：Cushing’s Syndrome Pheochromocytoma Apparent Excess of Mineralocorticoid Syndrome
摘 要：We report a new case of ectopic Cushing’s syndrome caused by an ACTH-producing pheochromocytoma. A 55-year-old woman presented with a history of severe proximal muscle weakness, polyuria, progressive virilization, anxiety, dyspnea on exercise, difficult to treat hypertension, and type 2 diabetes mellitus since 4 months. The laboratory data demonstrated ACTH-dependent hypercortisolism. The abdominal computed tomography scan showed a 30 mm well-defined mass in the left adrenal gland suggestive for pheochromocytoma. The adrenal veins were sampled, with intraprocedural cortisol measurement, to dosing selective ACTH and cathecolamines. The results established clearly the left adrenal gland as the source of ACTH overproduction. A left sided adrenalectomy was performed with subsequent resolution of Cushing’s syndrome. The patient was discharged in good clinical condition.
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