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An unsettling explanation for the failure of skatole-baited ovitraps to capture Culex mosquitoes

Insect Science 2019年第5期26卷 873-880页

作者： marcelo H.S.Paiva rosangela m.r.barbosa Suzane A.Santos Norma m.Silva marcia B.Paula Constancia F.J.Ayres Walter S.Leal Depariamento de Entomologia Instituto Aggeu MagalhaesFundagao Oswaldo CruzAv. Professor Moraes RegoRecifePEBrazil CentroAcademicodoAgreste Universidade Federalde Pernambuco CaruaruPEBrazil Departamentode Biologia Celular Embriologia e GeneticaCentro de Ciencias Biologicas Universidade Federal de Santa CatarinaFlorianopolisSC.Brazil Faculdade de Saude PCiblica Departamento de Epidemiologia Universidade de Sao PauloSao PauloSPBrazil Department of molecular and Cellular Biology University of California-DavisDavisCaliforniaUSA

Culex mosquitoes are primarily found in temperate and tropical regions worldwide where they play a crucial role as main vectors of filarial worms and arboviruses. In recife, a northeast city in Brazil, high densities of Culex quinquefasciatus are often found in association with human populated areas. In marked contrast to another part of the city, field tests conducted in the neighborhood of Sitio dos Pintos showed that trapping of mosquitoes in skatole-baited ovitraps did not differ significantly from captures in control (water) traps. Thus, classical and molecular taxonomic approaches were used to analyze the Culex species circulating in Sitio dos Pintos. results obtained from both approaches agreed on the cocirculation of Culex quinquefasciatus and Culex nigripalpus in three different areas of this neighborhood. What was initially considered as an unexpected failure of this lure turned out to be a more unsettling problem, that is, the first report in recife of Culex nigripalpus, a vector of Venezuelan equine encephalitis virus and West Nile virus. Unplanned urbanization processes close to remnants of the Atlantic forest, such as observed in Sitio dos Pintos, may have contributed to the introduction of Cx. nigripalpus in urban areas.

关键词： Culex quinquefasciatus Culex nigripalpus dengue oviposition attractant skatole West Nile virus Zika

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Concerns about the application of resistance exercise with blood-flow restriction and thrombosis risk in hemodialysis patients

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Journal of Sport and Health Science 2024年第4期13卷 548-558,F0003页

作者： Hugo de Luca Correa Lysleine Alves Deus Dahan da Cunha Nascimento Nicholas rolnick rodrigo Vanerson Passos Neves Andrea Lucena reis Thais Branquinho de Araujo Carmen Tzanno-martins Fernanda Silveira Tavares Luiz Sinesio Silva Neto Claudio Avelino rodrigues Santos Paolo Lucas rodrigues-Silva Fernando Honorato Souza Vitoria marra da motta Vilalva mestrinho rafael Lavarini dos Santos rosangela Vieira Andrade Jonato Prestes Thiago dos Santos rosa Post-graduate Program of Physical Education Catholic University of BrasıliaBrasılia 71966-700Brazil The Human Performance mechanic Lehman CollegeNew YorkNY 10011USA Clinical Group Home Dialysis Center and renalClass Sao Paulo 01239-040Brazil Department of medicine Catholic University of BrasıliaBrasılia 71966-700Brazil Faculty of medicine Federal University of TocantinsTocantins 77001-090Brazil Embrapa Genetic resources and Biotechnology Brasılia 70770-917Brazil Graduate Program of Genomic Sciences and Biotechnology Brasılia 71966-700Brazil

Background:Hemodialysis(HD) per se is a risk factor for *** the growing body of evidence on blood-flow restriction(BFr) exercise in HD patients,identification of possible risk factors related to the prothrombotic agent D-dimer is required for the safety and feasibility of this training *** aim of the present study was to identify risk factors associated with higher D-dimer levels and to determine the acute effect of resistance exercise(rE) with BFr on this ***:Two hundred and six HD patients volunteered for this study(all with a glomerular filtration rate of mL/min/1.73 m2).The rE+BFr session consisted of 50% arterial occlusion pressure during 50 min sessions of HD(intradialytic exercise).rE repetitions included concentric and eccentric lifting phases(each lasting 2 s) and were supervised by a strength and conditioning ***:Several variables were associated with elevated levels of D-dimer,including higher blood glucose,citrate use,recent cardiovascular events,recent intercurrents,higher inflammatory status,catheter as vascular access,older patients(>70 years old),and HD ***,rE+BFr significantly increases D-dimer after 4 *** with borderline baseline D-dimer levels(400-490 ng/mL) displayed increased risk of elevating D-dimer over the normal range(≥500 ng/mL).Conclusion:These results identified factors associated with a heightened prothrombotic state and may assist in the screening process for HD patients who wish to undergo rE+BFr.D-dimer and/or other fibrinolysis factors should be assessed at baseline and throughout the protocol as a precautionary measure to maximize safety during rE+BFr.

关键词： Blood-flow restriction Chronic kidney disease Coagulation Hemodialysis Vascular occlusion exercises

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Effect of music therapy on short-term psychological and physiological outcomes in mechanically ventilated patients: A randomized clinical pilot study

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Journal of Intensive medicine 2024年第04期04卷 515-525页

作者： Ettenberger m. Casanova-Libreros r. Chávez-Chávez J. Cordoba-Silva J.G. Betancourt-Zapata W. maya r. Fandiño-Vergara L.A. Valderrama m. Silva-Fajardo I. Hernández-Zambrano S.m. SONO - Centro de musicoterapia Bogotá Colombia Vice-rectorate for research Fundación Universitaria de Ciencias de la Salud Bogotá Colombia Department of Biomedical Engineering University of Los Andes Bogotá Colombia Department of rehabilitation Sociedad de Cirugía de Bogotá Hospital de San José Bogotá Colombia Faculty of Nursing Fundación Universitaria de Ciencias de la Salud Bogotá Colombia

Background: Elevated anxiety levels are common in patients on mechanical ventilation (mV) and may challenge recovery. research suggests music-based interventions may reduce anxiety during mV. However, studies investigating specific music therapy techniques, addressing psychological and physiological well-being in patients on mV, are scarce. methods: This three-arm randomized clinical pilot study was conducted with mV patients admitted to the intensive care unit (ICU) of Hospital San José in Bogotá, Colombia between march 7, 2022, and July 11, 2022. Patients were divided into three groups: intervention group 1 (IG1), music-assisted relaxation; intervention group 2 (IG2), patient-preferred therapeutic music listening; and control group (CG), standard care. The main outcome measure was the 6-item State-Anxiety Inventory. Secondary outcomes were: pain, measured with a visual analog scale; resilience, measured with the Brief resilience Scale; agitation/sedation, measured with the richmond Agitation–Sedation Scale; vital signs, including heart rate, blood pressure, oxygen saturation, and respiratory rate; days of mV; extubation success; and days in the ICU. Additionally, three patients underwent electroencephalography during the interventions. results: Data from 23 patients were analyzed in this study. The age range of the patients was 24–84 years, with a median age of 66 years (interquartile range: 57–74). Of the 23 patients, 19 were female (82.6%). No statistically significant differences between the groups were observed for anxiety (P=0.330), pain (P=0.624), resilience (P=0.916), agitation/sedation (P=0.273), length of ICU stay (P=0.785), or vital signs. A statistically significant difference between the groups was found for days of mV (P=0.019). Electroencephalography measurements showed a trend toward delta and theta band power decrease for two patients and a power increase on both beta frequencies (slow and fast) in the frontal areas of the brain for one patient. Co

关键词： Anxiety Intensive care unit mechanical ventilation music therapy Pain

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response to Commentary by Dr. matthew J. Clarkson on

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Journal of Sport and Health Science 2024年第5期13卷 670-671页

作者： Hugo de Luca Corrêa Lysleine Alves Deus Dahan da Cunha Nascimento Nicholas rolnick rodrigo Vanerson Passos Neves Andrea Lucena reis Thais Branquinho de Araújo Carmen Tzanno-martins Fernanda Silveira Tavares Luiz Sinésio Silva Neto Cláudio Avelino rodrigues Santos Paolo Lucas rodrigues-Silva Fernando Honorato Souza Vitória marra da motta Vilalva mestrinho rafael Lavarini dos Santos rosangela Vieira Andrade Jonato Prestes Thiago dos Santos rosa Post-graduate Program of Physical Education Catholic University of BrasıliaBrasılia 71966-700Brazil The Human Performance mechanic Lehman CollegeNew YorkNY 10011USA Clinical Group Home Dialysis Center and renalClass Sao Paulo 01239-040Brazil Department of medicine Catholic University of BrasıliaBrasılia 71966-700Brazil Faculty of medicine Federal University of TocantinsTocantins 77001-090Brazil Embrapa Genetic resources and Biotechnology Brasılia 70770-917Brazil g Graduate Program of Genomic Sciences and Biotechnology Brasılia 71966-700Brazil

Dear editor:We sincerely thank matthew *** for his insightful commentary1 on our recent publication in the Journal of Sport and Health Science.2 Clarkson's pioneering work in the development and application of blood flow restriction (BFr) exercise protocols has undeniably laid the groundwork for subsequent investigations in this field,including our own.(3-6)His commentary not only highlights the relevance and timeliness of our study but also offers valuable perspectives on refining safety considerations for intradialytic BFr exercise among hemodialysis patients.

关键词： patients application flow

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A comparative analysis of three different methods for the estimation of the basic reproduction number of dengue

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Infectious Disease modelling 2016年第1期1卷 88-100页

作者： rosangela Peregrina Sanches Eduardo massad School of medicine University of Sao PauloSao PauloSPBrazil London School of Hygiene and Tropical Diseases UK

The basic reproduction number,r0,is defined as the expected number of secondary cases of a disease produced by a single infection in a completely susceptible population,and can be estimated in several *** example,from the stability analysis of a compartmental model;through the use of the matrix of next generation,or from the final size of an epidemic,*** this paper we applied the method for estimating r0 of dengue fever from the initial growth phase of an outbreak,without assuming exponential growth of cases,a common assumption in many *** used three different methods of calculating r0 to compare the techniques'details and to evaluate how these techniques estimate the value of r0 of dengue using data from the city of ribeir^ao Preto(SE of Brazil)in two *** results of the three methods are numerically different but,when we compare them using a system of differential equations developed for modeling only the first generation time,we can observe that the methods differ little in the initial growth *** conclude that the methods predict that dengue will spread in the city studied and the analysis of the data shows that the estimated values of r0 have an equal pattern overtime.

关键词： Basic reproduction number Dengue mathematical models Likelihood-based model

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Optimizing the solar energy capture of residential roof design in the southern hemisphere through Evolutionary Algorithm

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能源与人工环境(英文) 2021年第4期2卷 406-424页

作者： Saleh Kaji Esfahani Ali Karrech robert Cameron mohamed Elchalakani rosangela Tenorio Fernando Jerez The Faculty of Arts BusinessLaw and EducationSchool of DesignUniversity of Western Australia6009 PerthWestern AustraliaAustralia Faculty of Engineering and mathematical Sciences School of EngineeringUniversity of Western Australia6009 PerthWestern AustraliaAustralia The Australian Urban Design research Centre University of Western Australia6000 PerthWestern AustraliaAustralia

Australia’s national energy system is heavily reliant on coal-fired power plants and requires quick action to de-crease CO_(2)emissions in order to meet the Paris climate change agreement by *** a good alternative to coal power,renewable resources can produce the required energy for Australia while keeping the environment *** annual amount of falling solar irradiation in Australia is a few thousand times higher than its energy consumption,but the amount of the collected solar energy is *** Perth,the sunniest city in Aus-tralia,one-third of the residential dwellings have roof-mounted solar collector ***,there have been limited studies into the integration of these systems in building design and it is still unknown which roof design can deliver maximum efficiency based on the local environmental ***,the aims of this study are to determine the optimum residential roof design in Perth,Western Australia and to maximise extracted solar power throughout a *** reach this aim,a combination of analytical modelling,numerical simulation,and evolutionary algorithm methods have been *** first,a series of detailed mathematical calculations were performed in Excel to find the optimum solar collector mounting *** the numerical simulation,the exam-ination was repeated in the rhino-Grasshopper interface to verify the earlier findings and calibrate the chosen simulation package with the help of parametric *** the last step,a wide range of housing roof shapes has been tested by evolutionary algorithm plugin-Galapagos,to find the optimum roof shape design in the given *** results show that,unlike the traditional approach and common belief,a roof shape with a 25-degree tilt angle,170-175 azimuth angle,and aspect ratio of 1:1.2 is optimum to gain maximum solar gaining ***,this study advances the knowledge of solar capturing by suggesting a new parameter-oblique angle-in finding the op

关键词： Parametric architecture Solar gaining roof form optimization Evolutionary algorithm

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ESWL for difficult bile duct stones:A 15-year single centre experience

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World Journal of Gastroenterology 2010年第33期16卷 4159-4163页

作者： rosangela muratori Francesco Azzaroli Federica Buonfiglioli Flavio Alessandrelli Paolo Cecinato Giuseppe mazzella Enrico roda Department of Digestive Diseases and Internal medicine S.Orsola-Malpighi HospitalUniversity of Bologna

AIm:To evaluate the efficacy of extracorporeal shock wave lithotripsy(ESWL)for the management of refractory bile duct cholelithiasis in a third level referral ***:The clinical records of all patients treated with a second generation electromagnetic lithotripter (Lithostar Plus,SIEmENS)from October 1990 to April 2005 were *** patients were monitored during the procedure and antibiotics were administered in case of ***χ 2 test and logistic regression analysis were performed as ***:Two hundred and fourteen patients(102 males,112 females;mean age 74.8±0.84 years-single stone 97,multiple stones 117)underwent *** mean number of sessions and shock waves were 3.5 ±0.13 and 3477.06±66.17,*** maximum stone size was 5 *** stone clearance was achieved in 192(89.7%)*** the remain-ing patients 15 required surgery,2 a palliative stent and in 5 patients stone fragmentation led to effective bile drainage with clinical resolution despite incomplete ***,sex and stone characteristics were not related to treatment *** complications occurred in two patients(haemobilia and rectal bleeding) and minor complications in 25(3 vomiting,22 arrhythmias).No procedure-related deaths ***:ESWL is a safe and effective technique for clearance of refractory bile duct stones.

关键词： Difficult bile duct stones Extracorporeal shock wave lithotripsy

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Carbon sequestration capability of Fagus sylvatica forests developing in the majella National Park (Central Apennines,Italy)

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Journal of Forestry research 2018年第6期29卷 1627-1634页

作者： Loretta Gratani Luciano Di martino Anna rita Frattaroli ANDrea Bonito Valter Di Cecco Walter De Simone Giorgia Ferella rosangela Catoni Department of Environmental Biology Sapienza University of Rome majella Seed Bank Majella National Park Department of Life Health and Environmental Sciences University of L'Aquila

Terrestrial ecosystems represent a major sink for atmospheric carbon(C) and temperate forests play an important role in global C cycling, contributing to lower atmospheric carbon dioxide(CO2) concentration through photosynthesis. The Intergovernmental Panel of Climate Change highlights that the forestry sector has great potential to decrease atmospheric CO2concentration compared to other sectoral mitigation activities. The aim of this study was to evaluate CO2sequestration(CO2S)capability of Fag us sylvatica(beech) growing in the Orfento Valley within majella National Park(Abruzzo,Italy). We compared F. sylvatica areas subjected to thinning(one high-forest and one coppice) and no-management areas(two high-forests and two coppices). The results show a mean CO2S of 44.3 ± 2.6 mg CO2ha-1a-1,corresponding to 12.1 ± 0.7 mg C ha-1a-1the no-managed areas having a 28% higher value than the managed areas. The results highlight that thinning that allows seed regeneration can support traditional management practices such as civic use in some areas while no management should be carried out in the reserve in order to give priority to the objective of conservation and naturalistic improvement of the forest heritage.

关键词： Beech Carbon sequestration Coppice High-forest Leaf area index

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Tumor budding predicts response to anti-EGFr therapies in metastatic colorectal cancer patients

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World Journal of Gastroenterology 2010年第38期16卷 4823-4831页

作者： Inti Zlobec Francesca molinari Vittoria martin Luca mazzucchelli Piercarlo Saletti rosangela Trezzi Sara De Dosso Tatjana Vlajnic milo Frattini Alessandro Lugli Institute for Pathology University Hospital Basel Institute of Pathology Division of medical Oncology Institute of Southern Switzerland

AIm:To investigate whether the evaluation of tumor budding can complement K-rAS analysis to improve the individualized prediction of response to anti-epidermal growth factor receptor based therapies in metastatic colorectal cancer (mCrC) patients. mETHODS:Forty-three patients with mCrC treated with cetuximab or panitumumab were entered into this study. According to the response Evaluation Criteria in Solid Tumors criteria, 30 patients had stable or progressive disease (non-responsive), while 13 patients had a partial response. Tumor buds were evaluated from whole tissue sections stained for pan-cytokeratin, evaluated in the densest region using a 40 × objective and "high-grade" tumor budding was defi ned as 15 buds/high-power f ***: Tumor buds and K-rAS mutation both correctly classif ied 68% of patients. All patients with K-rAS mutation (n=7) or high-grade tumor budding (n=11) were non-responsive, of which 4 patients had both features. All 13 partial responders were K-rAS wild-type with low-grade tumor budding. Combined, the predictive value of K-rAS and tumor budding was 80%. Additionally, high-grade tumor budding was significantly related to worse progression-free survival [Hr (95% CI): 2.8 (1.3-6.0, P=0.008)].CONCLUSION: If confirmed in larger cohorts, the addition of tumor budding to K-rAS analysis may represent an effective approach for individualized patient management in the metastatic setting.

关键词： Anti-epidermal growth factor receptor therapy Colorectal cancer K-rAS Prognosis Tumor budding

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A Local Ensemble Transform Kalman Filter Data Assimilation System for the Global FSU Atmospheric model

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Journal of mechanics Engineering and Automation 2015年第3期5卷 185-196页

作者： rosangela Saher Cintra Steve Cocke Laboratory of Computation and Applied mathematics National Institute for Space Research S6o Jos~ dos Campos 12227010 Brazil Center of Ocean-Atmospheric Prediction Studies Florida State University Tallahassee Florida USA

Data assimilation is the process by which measurements and model predictions are combined to obtain an accurate representation of the state of the modeled system. We implemented a data assimilation scheme called LETKF （local ensemble transform Kalman filter） with FSUGSm （Florida State University Global Spectral model） and made an experiment to evaluate the initial condition generated to numerical weather prediction to FSUGSm model. The LETKF analysis carries out independently at each grid point with the use of ＂local＂ observations. An ensemble of estimates in state space represents uncertainty. The FSUGSm is a multilevel （27 vertical levels） spectral primitive equation model, where the variables are expanded horizontally in a truncated series of spherical harmonic functions （at resolution T63） and a transform technique is applied to calculate the physical processes in real space The assimilation cycle runs on the period 01/01/2001 to 31/01/2001 at （00, 06, 12 and 18 GmT） for each day. We examined the atmospheric fields during the period and the OmF （observation-minus-forecast） and the OmA （observation-minus-analysis） statistics to verify the analysis quality comparing with forecasts and observations. The analyses present stability and show suitable to initiate the weather predictions.

关键词： Data assimilation Kalman filter numerical weather prediction global atmospheric model.

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