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Cardiovascular prevention in elderly patients

Journal of Geriatric Cardiology 2022年第5期19卷 377-392页

作者： Clara Bonanad rosa Fernández-Olmo Sergio García-Blas Jose Antonio Alarcon Pablo Díez-Villanueva Carmen Rus Mansilla Héctor García-Pardo Pablo Toledo Ana Ayesta Eva Pereira Antoni Carol Almudena Castro-Conde Carmen de Pablo-Zarzoso Manuel Martínez-Sellés Vicente Arrarte Raquel Campuzano Albert Ariza-Solé Servicio de Cardiología Hospital Clínico Universitario de ValenciaValenciaSpain Instituto de Investigación Sanitaria INCLIVA ValenciaSpain Servicio Cardiología Hospital Universitario de Jaén Spain Servicio Cardiología Hospital de Donosti Spain Servicio de Cardiología Hospital Universitario La Princesa de MadridSpain Servicio de Cardiología Hospital Alto Gudalquivir de AndújarJaénSpain Servicio de Cardiología Hospital Rio Hortega de ValladolidSpain Servicio Cardiología Hospital Clínico San Cecilio de Granada Spain Servicio de Cardiología Hospital Universitario Central de AsturiasSpain Servicio de Cardiologia Hospital de LugoSpain Servicio de Cardiología Hospital Moisés Broggi de BarcelonaSpain Servicio de Cardiología Hospital Universitario de la Paz de Madrid Spain Servicio de Cardiología Hospital Ramón y Cajal de MadridSpain Department of Cardiology.Hospital Universitario Gregorio Marañón CIBERCV.Universidad EuropeaUniversidad Compluten Servicio de Cardiología del Hospital General de Alicante Spain Servicio de Cardiología Hospital Universitario Fundación de Alcorcón de MadridSpain Servicio de Cardiología Hospital Bellvitge de BarcelonaBioheartGrup de Malalties CardiovascularsInstitut d’InvestigacióBiomèdica de BellvitgeIDIBELLL’Hospitalet de LlobregatBarcelonaSpain

In recent decades,life expectancy has been increasing *** this scenario,health interventions are ne-cessary to improve prognosis and quality of life of elderly with cardiovascular risk factors and cardiovascular ***,the number of elderly patients included in clinical trials is low,thus current clinical practice guidelines do not include specific *** document aims to review prevention recommendations focused in patients≥75 years with high or very high cardiovascular risk,regarding objectives,medical treatment options and also including physical exercise and their inclusion in cardiac rehabilitation ***,we will show why geriatric syndromes such as frailty,dependence,cognitive impair-ment,and nutritional status,as well as comorbidities,ought to be considered in this population regarding their important pro-gnostic impact.

关键词： prevention patients cardiovascular

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Deformation history and processes during accretion of seamounts in subduction zones:The example of the Durkan Complex(Makran,SE Iran)

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Geoscience Frontiers 2023年第2期14卷 182-203页

作者： Edoardo Barbero Maria Di rosa Luca Pandolfi Morteza Delavari Asghar Dolati Federica Zaccarini Emilio Saccani Michele Marroni Dipartimento di Fisica e Scienze della Terra Universitàdi Ferrara44123 FerraraItaly Istituto di Geoscienze e Georisorse Consiglio Nazionale delle Ricerche(CNR)10125 TorinoItaly Dipartimento di Scienze della Terra Universitàdi Pisa56126 PisaItaly Istituto di Geoscienze e Georisorse Consiglio Nazionale delle Ricerche(CNR)56124 PisaItaly Faculty of Earth Sciences Kharazmi UniversityTehran 15719-19911Iran Department of Applied Geological Sciences and Geophysics University of Leoben8700 LeobenAustria

The Durkan Complex is a tectonic element of the Makran Accretionary Prism(SE Iran)that includes fragments of Late Cretaceous *** this paper,the results of map-to micro-scale structural studies of the western Durkan Complex are presented with the aim to describe its structural and tectonometamorphic *** Durkan Complex consists of several tectonic units bordered by mainly NNW-striking *** main deformation phases(D_(1),D_(2),and D_(3))are distinguished and likely occurred from the Late Cretaceous to the Miocene–Pliocene.D_(1) is characterized by sub-isoclinal to close and W-verging folds associated with an axial plane foliation and shear zone along the fold *** phase records the accretion of fragments of the seamount within the Makran at blueschist facies metamorphic conditions(160–300℃ and 0.6–1.2 GPa).D_(2) is characterized by open to close folds with subhorizontal axial plane that likely developed during the exhumation of previously accreted seamount *** upper Paleocene–Eocene siliciclastic succession unconformably sealed the D_(1) and D_(2) structures and is,in turn,deformed by W-verging thrust faults typical of D_(3).The latter likely testifies for a Miocene–Pliocene tectonic reworking of the accreted seamount fragments with the activation of out of sequence *** results shed light on the mechanism of accretion of seamount materials in the accretionary prisms,suggesting that seamount slope successions favour the localization and propagation of the basal dé*** study further confirms that the physiography of the subducting plates plays a significant role in the tectonic evolution of the subduction complexes.

关键词： Underplated seamount Makran Accretionary Prism Tectono-sedimentary evolution Tectono-metamorphic evolution Cretaceous Iran

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Development of family resilience models

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Frontiers of Nursing 2023年第1期10卷 3-7页

作者： Min Yang Shuang Yang Ronnell D Dela rosa Lu-Hai Cui School of Nursing Binzhou Medical UniversityBinzhouShandong 256603China Department of Dermato-Venereal Binzhou Medical University HospitalBinzhouShandong 256603China School of Nursing Philippine Women’s UniversityManila 1004Philippines College of Nursing and Midwifery Bataan Peninsula State UniversityBataan 2100Philippines

Family resilience is not the sum of the individual psychological resilience of each of the family members,but the family itself as a unit of resilience *** representative models of family stress tolerance theory mainly include Mc Cubbin's series of family stress tolerance models and Walsh's family stress tolerance framework,which are widely used in the practice of family *** the future,empirical studies on family resilience should be strengthened,measurement tools with high reliability and validity should be established,and the combination of family resilience theory and community-based practice should be promoted.

关键词： concept family resilience model theoretical study

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Fatty acids in microalgae and cyanobacteria in a changing world:Contrasting temperate and cold environments

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BIOCELL 2022年第3期46卷 607-621页

作者： MARCELO P.hernANDO IRENE R.SCHLOSS FLORENCIA DE LA rosa MARLEEN DE TROCH Comisión Nacional de Energía Atómica(CNEA) Centro Atómico ConstituyentesDepartamento de RadiobiologíaSan MartínBuenos AiresArgentina Red de Investigación de Estresores Marinos-costeros en América Latina y el Caribe(REMARCO) Mar del Plata7602Argentina Instituto Antártico Argentino(IAA) San MartínBuenos AiresArgentina Centro Austral de Investigaciones Científicas(CADIC-CONICET) Ushuaia9410Argentina Universidad Nacional de Tierra del Fuego Ushuaia9410Argentina Instituto de Ciencias Básicas y Experimentales(ICBE) Universidad de MorónMorónBuenos AiresArgentina Consejo Nacional de Investigaciones Científicas y Técnicas(CONICET) Buenos AiresArgentina Ghent University Faculty of SciencesBiology DepartmentMarine BiologyGhent9000Belgium

Under the present changing climate conditions and the observed temperature increase,it is of high importance to understand its effects on aquatic microbial life,and organisms’adaptations at the biochemical *** adjust to temperature or salinity stress and avoid cell damage,organisms alter their degree of fatty acids(FAs)***,temperature is expected to have strong effects on both the quantity and quality of FAs in aquatic *** we review some recent findings about FAs sensitivity to climate change in contrasting ***,heat waves may induce changes in the relative abundance of polyunsaturated FAs(PUFA).However,the impact of the exposure to warming waters is different in temperate and polar *** cold marine waters,high concentration of omega-3(ω3)FAs such as eicosapentaenoic acid(EPA)is promoted due to the activation of the desaturase *** this way,cells have enough energy to produce or activate antioxidant protection mechanisms and avoid oxidative stress due to heat ***,under high irradiance and heat wave conditions in temperate environments,photosystems’protection is achieved by decreasing EPA concentration due to desaturase *** FAs are transferred in aquatic food ***,any alteration in the production of essential FAs by phytoplankton(the main source ofω3)due to climate warming can be transferred to higher trophic levels,with cascading effects for the entire aquatic ecosystem.

关键词： Antarctic Temperate Essential FAs Increased temperature Microalgae Cyanobacteria

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Bioinformatic Analysis of Potential Pathogenicity Effectors of <i>Candidatus</i>Liberibacter asiaticus, Causal Agent of Citrus Huanglongbing

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American Journal of Plant Sciences 2020年第8期11卷 1319-1330页

作者： Felipe Roberto Flores-de la rosa Cynthia Guadalupe Rodríguez-Quibrera Cristian Matilde-hernández Ricardo Santillán-Mendoza Campo Experimental Ixtacuaco Instituto Nacional de Investigaciones Forestales Agrícolas y Pecuarias (INIFAP) Km 4.5 Carretera Federal Martínez de la Torre-Tlapacoyan Tlapacoyan Veracruz México

Huanglongbing (HLB) or citrus greening is currently the most important citrus disease, caused by the bacterium Candidatus Liberibacter asiaticus (CLas). The impossibility of isolating it causes understanding its pathogenic mechanisms to be a complicated task. Recent studies identified 16 proteins with the signal peptide needed to be secreted in the plant and cause the disease. The present study aims to perform a bioinformatic analysis of these proteins with the function prediction approach by gene ontology (GO) and the detection of conserved domains. It was observed that of the 16 proteins analyzed not all are found in different infective strains reported in the literature. The GO analysis allowed us to relate different proteins with the biological process of energy and pathogenic activity, especially CLIBASIA_03315 and CLIBASIA_05115, respectively. The domain analysis allowed the observation of a β-CA domain, tentatively related to the damage caused to the chloroplast and a PAAR domain associated with the T6SS secretory system. Our results provide information on the possible function of potential pathogenicity effectors in CLas.

关键词： Effectors Proteins Function Prediction Gen Ontology Domains Citrus Greening

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Estimation of aboveground biomass of arboreal species in the semi-arid region of Brazil using SAR(synthetic aperture radar)images

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Journal of Arid Land 2023年第6期15卷 695-709页

作者： Janisson B de JESUS Tatiana M KUPLICH Íkaro D de C BARRETO Fernando L HILLEBRAND Cristiano N da rosa Postgraduate Program in Remote Sensing Federal University of Rio Grande do SulCampus ValePorto Alegre 91501970Brazil National Institute for Space Research(INPE) COESU(Southern Spatial Coordination)Santa Maria 97105970Brazil Postgraduate Program Biometry and Applied Statistics Rural Federal University of PernambucoRecife 52171900Brazil Federal Institute of Education Science and Technology of Rio Grande do Sul(IFRS)Campus RolanteRolante 95690000Brazil Postgraduate Program in Remote Sensing Polar and Climate CenterFederal University of Rio Grande do SulPorto Alegre 91501970Brazil

The Caatinga biome is an important ecosystem in the semi-arid region of *** has significantly degraded due to human activities and is currently a region undergoing ***,monitoring the variation in the Caatinga biome has become essential for its sustainable ***,traditional methods for estimating aboveground biomass(AGB)are time-consuming and *** sensing,such as optical and radar imaging,can estimate and correlate with ***,radar imaging is still a novelty to be applied in estimating the AGB of this biome,which is an area with little ***,this study aimed to use Sentinel-1 images to estimate the AGB of the Caatinga biome in Sergipe State(northeastern Brazil)and to verify its influencing *** sample plots(30 m×30 m)were selected,and the stems of individuals with a circumference at breast height(1.3 m above the ground)equal to or greater than 6.0 cm were measured,and the AGB through an allometric equation was *** Sentinel-1 images from 3 different periods(green,intermediate,and dry periods)were used to consider the phenological conditions of the Caatinga *** the pre-processing and extraction of attributes(co-polarized VV(vertical transmit and vertical receive),cross-polarized VH(vertical transmit and horizontal receive),and band ratio VH/VV backscatter,radar vegetation index,dual polarization synthetic aperture radar(SAR)vegetation index(DPSVI),entropy(H),and alpha angle(α))were performed with Sentinel’s Application *** attributes were used to estimate the AGB through simple and multiple linear regressions and evaluated by the coefficients of determination(R2),correlation(r),and root mean squared error(RMSE).The results showed that the attributes individually had little ability to estimate the AGB of the Caatinga biome in the three *** with multiple regression,we found that the intermediate period presented the equation with the best

关键词： Caatinga tropical dry forest coherent and incoherent attributes C-band Sentinel-1

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Implementation of the Hough Transform for Iris Detection and Segmentation

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Advances in Molecular Imaging 2019年第1期9卷 6-18页

作者： Francisco Javier Paulín-Martínez Alberto Lara-Guevara rosa María Romero-González Hugo Jiménez-hernández Facultad de Informática Universidad Autónoma de Querétaro Querétaro México

The iris is used as a reference for the study of unique biometric marks in people. The analysis of how to extract the iris characteristic information represents a fundamental challenge in image analysis, due to the implications it presents: detection of relevant information, data coding schemes, etc. For this reason, in the search for extraction of useful and characteristic information, approximations have been proposed for its analysis. In this article, it is presented a scheme to extract the relevant information based on the Hough transform. This transform helps to find primitive geometries in the irises, which are used to characterize each one of these. The results of the implementation of the algorithm of the Hough transform applied to the location and segmentation of the iris by means of its circumference are presented in the paper. Two public databases of iris images were used: UBIRIS V2 and CASIA-IrisV4, which were acquired under the same conditions and controlled environments. In the pre-processing stage the edges are found from the noise elimination in the image through the Canny detector. Subsequently, to the images of the detected edges, the Hough transform is applied to the disposition of the geometries detected.

关键词： Image Processing Iris Segmentation Hough Transform

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Lamb-dip saturated-absorption cavity ring-down rovibrational molecular spectroscopy in the near-infrared

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Photonics Research 2022年第8期10卷 1803-1809页

作者： ROBERTO AIELLO VALENTINA DI SARNO MARIA GIULIA DELLI SANTI MAURIZIO DE rosa IOLANDA RICCIARDI GIOVANNI GIUSFREDI PAOLO DE NATALE LUIGI SANTAMARIA PASQUALE MADDALONI Consiglio Nazionale delle Ricerche-Istituto Nazionale di Ottica Via Campi Flegrei 3480078 PozzuoliItaly Istituto Nazionale di Fisica Nucleare Sez.di NapoliComplesso Universitario di M.S.AngeloVia Cintia80126 NapoliItaly ppqSense S.r.l. Via Gattinella 2050013 Campi BisenzioItaly Consiglio Nazionale delle Ricerche-Istituto Nazionale di Ottica Largo E.Fermi 650125 FirenzeItaly Agenzia Spaziale Italiana Contrada Terlecchia75100 MateraItaly

The high-detection-sensitivity saturated-absorption cavity ring-down(SCAR)technique is extended to Lambdip spectroscopy of rovibrational molecular transitions in the near-infrared ***-comb-referenced sub-Doppler saturation measurements,performed on the acetylene(ν_(1)+ν_(3)+ν_(4)←ν_(4))R(14)e line at6562 cm^(-1),are analyzed by a SCAR global line profile fitting routine,based on a specially developed theoretical *** to a conventional cavity ring-down evaluation,our approach yields dip profiles with a linewidth freed from saturation broadening effects,reduced by 40%,and a signal-to-noise ratio increased by 90%.Ultimately,an overall(statistical and systematic)fractional uncertainty as low as 7×10^(-12)is achieved for the absolute line-center *** the same time,our method is also able to accurately infer the linear(nonsaturated)behavior of the gas absorption,providing Lamb-dip-based line strength measurements with a relative uncertainty of 0.5%.

关键词： saturated cavity absorption

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Flow Dynamics around Two Side by Side Circular Cylinders with Alternating Movements

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World Journal of Mechanics 2023年第1期13卷 1-19页

作者： Alice rosa da Silva Faculty of Civil Engineering Federal University of Uberlandia Uberlandia-MG Brazil

The flow dynamics is analyzed through two-dimensional numerical simulations around two circular cylinders arranged side by side, with 4 combinations of alternating motions. All simulations are performed for Re = 1000, amplitude of oscillation (A) equal to 3, frequency ratio (fr) of 0.5, specific rotation (α) equal to 0.5 and different values of spacing ratio (L/D). It is verified that the combination of the type of movement, together with the position of one cylinder in relation to the other, exerts significant influence on the flow dynamics, as well as on the pressure distribution around the cylinder surface and on the average values of the fluid dynamics coefficients. The smallest value of the average pressure coefficient (Cp = -3.3), is obtained for the oscillating cylinder when placed side by side with the clockwise rotation cylinder, case 3 and L/D = 1.5. On the other hand, the lowest mean drag coefficient (Cd = 1.0788), is obtained for the cylinder with counterclockwise rotation, located in the lower position in relation to oscillating cylinder in the upper position, with spacing between them of 1.5. Furthermore, it is observed that the rotation movement is more effective in reducing drag than the rotation-oscillation movement, for the studied frequency ratio.

关键词： Rotation Rotation-Oscillation Flow Dynamic Circular Cylinder

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Usefulness of the CONUT index upon hospital admission as a potential prognostic indicator of COVID-19 health outcomes

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Chinese Medical Journal 2022年第2期135卷 187-193页

作者： Adrian K.Bengelloun Guillermo J.Ortega Julio Ancochea Ancor Sanz-Garcia Diego A.Rodriguez-Serrano Guillermo Fernandez-Jimenez rosa Giron Elena Avalos Joan B.Soriano J.Ignacio de Ulibarri Facultad de Medicina Universidad Autónoma de MadridMadridSpain Unidad de Análisis de Datos Instituto de Investigación Sanitaria del Hospital de la PrincesaMadridSpain Servicios de Neumología Admisión y Documentación ClínicaCuidados Intensivos y Nutrición y DietéticaHospital Universitario de La PrincesaMadridSpain Centro de Investigación en Red de Enfermedades Respiratorias(CIBERES) Instituto de Salud Carlos III(ISCIII)MadridEspañaSpain

Background:In-hospital mortality in patients with coronavirus disease 2019(COVID-19)is *** prognostic indices are needed to identify patients at high-risk of COVID-19 health *** aimed to determine the usefulness of the CONtrolling NUTritional status(CONUT)index as a potential prognostic indicator of mortality in COVID-19 patients upon hospital ***:Our study design is of a retrospective observational study in a large cohort of COVID-19 *** addition to descriptive statistics,a Kaplan-Meier mortality analysis and a Cox regression were performed,as well as receiver operating curve(ROC).Results:From February 5,2020 to January 21,2021,there was a total of 2969 admissions for COVID-19 at our hospital,corresponding to 2844 ***,baseline(within 4 days of admission)CONUT index could be scored for 1627(57.2%)***’age was 67.3±16.5 years and 44.9%were *** CONUT severity distribution was:194(11.9%)normal(0-1);769(47.2%)light(2-4);585(35.9%)moderate(5-8);and 79(4.9%)severe(9-12).Mortality of 30 days after admission was 3.1%in patients with normal risk CONUT,9.0%light,22.7%moderate,and 40.5%in those with severe CONUT(P<0.05).An increased risk of death associated with a greater baseline CONUT stage was sustained in a multivariable Cox regression model(P<0.05).An increasing baseline CONUT stage was associated with a longer duration of admission,a greater requirement for the use of non-invasive and invasive mechanical ventilation,and other clinical outcomes(all P<0.05).The ROC of CONUT for mortality had an area under the curve(AUC)and 95%confidence interval of 0.711(0.676-0746).Conclusion:The CONUT index upon admission is potentially a reliable and independent prognostic indicator of mortality and length of hospitalization in COVID-19 patients.

关键词： Admission Clinical risk CONUT COVID-19 Prognosis Score

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