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Structural Properties of Ions and Polyelectrolytes in Aqueous Solutions under External Electric Fields:The Sign Effect

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Chinese Journal of Polymer Science 2024年第9期42卷 1341-1352,I0007页

作者： Cheng-Jiang li. jun-jun Wang Yuan Jiang Shu-li.Chen Hong-Fei li.Wen-Han Zhao Qing-rong Huang Chang-Ru rong Xiao-Zheng Duan State Key Laboratory of Polymer Physics and Chemistry Changchun Institute of Applied ChemistryChinese Academy of SciencesChangchun130022China School of Appli.d Chemistry and Engineering University of Science and Technology of ChinaHefei230026China National Key Laboratory of Advanced Vehicle Integration and Control China FAW Group Co.Ltd.Changchun130013China State Key Laboratory of Molecular Engineering of Polymers Department of Macromolecular ScienceFudan UniversityShanghai200438China Department of Food Science Rutgers University65 Dudley RoadNew BrunswickNew Jersey08901USA

We utili.e molecular dynamics simulations to investigate the microstructures of ions and polyelectrolytes in aqueous solutions under external electric *** focusing on the multi-body interactions between ionic components and H_(2)O molecules,as well as their responses to the external electric fields,we clarify several nontrivial molecular features of the ionic and polyelectrolyte solutions,such as the solvations of cations and anions,clustering of the ions,and dispersions/aggregations of polyelectrolyte chains,as well as the corresponding responses of H_(2)O molecules in these *** simulations illustrate the variations in structures of ionic solutions caused by reversing the charge sign of the ions,and elucidate the disparity in structures between anionic and cationic polyelectrolyte solutions in the presence of the external electric *** work clarifies the mechanism for the alternations in complex multi-body interactions in aqueous solutions caused by the appli.ation electric field,which can contribute to the fundamental understanding of the physical and chemical natures of ion-containing and charged polymeric systems.

关键词： Polyelectrolyte Ions Aqueous solutions External electric fields Asymmetric dipole

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Ferritinophagy: A new idea for li.er diseases regulated by ferroptosis

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Hepatobili.ry & Pancreatic Diseases International 2024年第2期23卷 160-170页

作者： Zi-Bing Qian jun-Feng li.Wan-Yuan Xiong Xiao-rong Mao The First Cli.ical Medical College of Lanzhou University Lanzhou 730000China Institute of Infectious Diseases The First Hospital of Lanzhou UniversityLanzhou 730000China Department of Infectious Disease The First Hospital of Lanzhou UniversityLanzhou 730000China

Background:The discovery of regulatory cell death has led to a breakthrough in the therapeutic *** forms of cell death,such as necrosis,apoptosis,pyroptosis,autophagy,and ferroptosis,play an important role in the development of li.er *** general,more than one form of cell death pathways is responsible for the disease ***,it is particularly important to study the regulation and interaction of various cell death forms in li.er *** sources:We performed a PubMed search up to November 2022 with the following keywords:ferritinophagy,ferroptosis,and li.er *** also used terms such as signal path,inducer,and inhibitor to supplement the query ***:This review summarized the basic characteristics of ferritinophagy and ferroptosis and the regulation of ferroptosis by ferritinophagy and reviewed the key targets and treatment strategies of ferroptosis in different li.er ***:Ferritinophagy is a potential therapeutic target in ferroptosis-related li.er diseases.

关键词： Ferritinophagy Ferroptosis li.er disease

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Effects of Acupotomy on Immobili.ation-Induced Gastrocnemius Contracture and Fibrosis in Rats via Wnt/β-Catenin Signali.g

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Chinese Journal of Integrative Medicine 2024年第7期30卷 633-642页

作者： HU Rui PAN jun-kang li.Jia-hui ZHANG Han li.Shao-rong ZHANG Yi School of Acupuncture-Moxibustion and Tuina Beijing University of Chinese MedicineBeijing100029China Acupuncture Department Kunming Municipal Hospital of Traditional Chinese MedicineKunming650500China

Objective To determine whether acupotomy ameli.rates immobili.ation-induced muscle contracture and fibrosis via Wnt/β-catenin signali.g *** Thirty Wistar rats were randomly divided into 5 groups(n=6)by a random number table,including control,immobili.ation,passive stretching,acupotomy,and acupotomy 3 weeks(3-w)*** rat model of gastrocnemius contracture was establi.hed by immobili.ing the right hind li.b in plantar flexion for 4 *** in the passive stretching group received passive stretching at gastrocnemius,a daily series of 10 repetitions for 30 s each at 30-s intervals for 10 consecutive *** in the acupotomy and acupotomy 3-w groups received acupotomy once and combined with passive stretching at gastrocnemius a daily series of 10 repetitions for 30 s each at 30-s intervals for 10 consecutive ***,rats in the acupotomy 3-w group were allowed to walk freely for 3 weeks after 10-day *** treatment,range of motion(ROM),gait analysis[i.e.,paw area,stance/swing and maximum ratio of paw area to paw area duration(Max dA/dT)],gastrocnemius wet weight and the ratio of muscle wet weight to body weight(MWW/BW)were *** morphometric and muscle fiber cross-sectional area(CSA)were assessed by hematoxyli.-eosin ***-related mRNA expressions(i.e.,Wnt 1,β-catenin,axin-2,α-smooth muscle actin,fibronectin,and types I and III collagen)were measured using real-time quantitative polymerase chain *** 1,β-catenin and fibronectin concentrations were measured by enzyme-li.ked immunosorbent *** I and III collagen in the perimysium and endomysium were analyzed using *** Compared with the control group,ROM,gait function,muscle weight,MWW/BW and CSA were significantly decreased in the immobili.ation group(all P<0.01),while protein levels of types I and III collagen,Wnt 1,β-catenin,fibronectin and mRNA levels of fibrosis-related genes were obviously increased(all P<0.01).Tr

关键词： acupotomy immobili.ation muscle contracture muscle fibrosis Wnt/β-catenin signali.g

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Self-Triggered Set Stabili.ation of Boolean Control Networks and Its Appli.ations

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IEEE/CAA Journal of Automatica Sinica 2024年第7期11卷 1631-1642页

作者： rong Zhao jun-e Feng Dawei Zhang the School of Mathematics Shandong UniversityShandong UniversityJinan 250100China

Set stabili.ation is one of the essential problems in engineering systems, and self-triggered control(STC) can save the storage space for interactive information, and can be successfully appli.d in networked control systems with li.ited communication resources. In this study, the set stabili.ation problem and STC design of Boolean control networks are investigated via the semi-tensor product technique. On the one hand, the largest control invariant subset is calculated in terms of the strongly connected components of the state transition graph, by which a graph-theoretical condition for set stabili.ation is derived. On the other hand, a characteristic function is exploited to determine the triggering mechanism and feasible controls. Based on this, the minimum-time and minimum-triggering open-loop, state-feedback and output-feedback STCs for set stabili.ation are designed,respectively. As classic appli.ations of self-triggered set stabili.ation, self-triggered synchronization, self-triggered output tracking and self-triggered output regulation are discussed as well. Additionally, several practical examples are given to illustrate the effectiveness of theoretical results.

关键词： Boolean control networks(BCNs) output regulation self-triggered control semi-tensor product of matrices set stabili.ation synchronization

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Learning in games:a systematic review

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Science China(Information Sciences) 2024年第7期67卷 133-159页

作者： rong-jun QIN Yang YU National Key Laboratory for Novel Software Technology Nanjing University Poli.ir Technologies

Game theory studies the mathematical models for self-interested individuals. Nash equili.rium is arguably the most central solution in game theory. While finding the Nash equili.rium in general is known as polynomial parity arguments on directed graphs(PPAD)-complete, learning in games provides an alternative to approximate Nash equili.rium, which iteratively updates the player's strategy through interactions with other players. Rules and models have been developed for learning in games, such as fictitious play and no-regret learning. Particularly, with recent advances in onli.e learning and deep reinforcement learning,techniques from these fields greatly boost the breakthroughs in learning in games from theory to *** a result, we have witnessed many superhuman game AI systems. The techniques used in these systems evolve from conventional search and learning to purely reinforcement learning(RL)-style learning methods,gradually getting rid of the domain knowledge. In this article, we systematically review the above techniques,discuss the trend of basic learning rules towards a unified framework, and recap appli.ations in large ***, we discuss some future directions and make the prospect of future game AI systems. We hope this article will give some insights into designing novel approaches.

关键词： non-cooperative games learning in games no-regret learning reinforcement learning superhuman AI

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Recent advancements in hydrometallurgical recycli.g technologies of spent li.hium-ion battery cathode materials

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Rare Metals 2024年第3期43卷 879-899页

作者： Juan Wu li.Xiao li.Shen Jian-jun Ran Hui Zhong Yi-rong Zhu Han Chen College of Materials and Advanced Manufacturing Hunan University of TechnologyZhuzhou412007China School of Resources Processing and Bioengineering Central South UniversityChangsha410083China Guangdong JiaNa Energy Technology Company Qingyuan513000China

The rapidly increasing production of li.hium-ion batteries(li.s)and their li.ited service time increases the number of spent li.s,eventually causing serious environmental issues and resource *** the perspectives of clean production and the development of the li. industry,the effective recovery and recycli.g of spent li.s require urgent *** study provides an overview of the current hydrometallurgical processes employed in the recycli.g of spent cathode materials,focusing on the leaching of valuable metals and their *** particular,this research reviews the various leaching systems(inorganic acid,organic acid,and ammonia)and the separation of valuable metals,and then,recommendations for subsequent study are offered in an attempt to contribute to the development of highly efficient methods for recycli.g spent cathode *** addition,a range of existing technologies,such as solvent extraction,chemical precipitation,electrochemical deposition,and regeneration,for the postprocessing of leaching solutions are ***,the promising technologies,existing challenges and suggestions with respect to the development of effective and environmentally friendly recycli.g methods for handli.g spent cathode materials are identified.

关键词： Spent li.hium-ion batteries(li.s) Cathode material Hydrometallurgy Leaching Recycli.g

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Subarachnoid hemorrhage misdiagnosed as acute coronary syndrome leading to catastrophic neurologic injury: A case report

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World Journal of Cli.ical Cases 2024年第1期12卷 148-156页

作者： jun-Ming li. Xiao-jun Yuan Guang li.Xin-rong Gan Wen-Hua Xu Department of Orthopaedic Surgery People's Hospital of Yichun CityYichun 336000Jiangxi ProvinceChina

BACKGROUND Elevated levels of cardiac troponin and abnormal electrocardiogram changes are the primary basis for cli.ical diagnosis of acute coronary syndrome(ACS).Troponin levels in ACS patients can often be more than 50 times the upper reference *** patients with subarachnoid hemorrhage(SAH)also show electrocardiogram abnormali.ies,myocardial damage,and elevated cardiac *** ACS patients,patients with SAH only have a sli.ht increase in troponin,and the use of anticoagulants or antiplatelet drugs is *** of the opposite treatment modali.ies,it is essential for cli.icians to distinguish between SAH and *** SUMMARY A 56-year-old female patient was admitted to the emergency department at night with a sudden onset of severe back *** final diagnosis was intraspinal hematoma in the thoracic *** performed an emergency thoracic spinal canal hematoma evacuation procedure with the assistance of a ***,diffuse hematoma formation was found in the T7-T10 spinal canal,and no obvious spinal vascular malformation changes were *** head and spinal magnetic resonance imaging(MRI)showed a small amount of SAH in the skull,no obvious abnormali.ies in the cervical and thoracic spinal canals,and no abnormal signals in the lumbar spinal ***-dominal aorta computed tomography angiography showed no vascular *** motor system examination showed Medical Research Council Scale grade 1/5 strength in both lower extremities,and the patient experienced decreased sensation below the T12 rib margin and reported a Visual Analog Scale score of *** Extremely elevated troponin levels(more than 50 times the normal range)are not unique to coronary artery *** can also result in extremely high troponin levels,and antiplatelet drugs are contraindicated in such *** MRI can help in the early differential diagnosis,as a misdiagnosis of ACS can lead to catastroph

关键词： Acute coronary syndrome Spontaneous spinal subdural hematoma Misdiagnosis Catastrophic neurological injury Case report

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Vibration Control of A Flexible Marine Riser System Subject to Input Dead Zone and Extraneous Disturbances

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China Ocean Engineering 2024年第2期38卷 271-284页

作者： ZHOU li.WANG Guo-rong WAN Min School of Mechatronic Engineering Southwest Petroleum UniversityChengdu 610500China Energy Equipment Institute Southwest Petroleum UniversityChengdu 610500China National Key Laboratory of Oil and Gas Reservoir Geology and Exploitation Southwest Petroleum UniversityChengdu 610500China

An observer-based adaptive backstepping boundary control is proposed for vibration control of flexible offshore riser systems with unknown nonli.ear input dead zone and uncertain environmental *** control algorithm can update the control law onli.e through real-time data to make the controller adapt to the environment and improve the control ***,based on the adaptive backstepping framework,virtual control laws and Lyapunov functions are designed for each *** direction interference observers are designed to track the timevarying boundary *** this basis,the inverse of the dead zone and li.ear state transformation are used to compensate for the original system and eli.inate the adverse effects of the dead *** addition,the stabili.y of the closed-loop system is proven by Lyapunov stabili.y *** the system states are bounded,and the vibration offset of the riser converges to a small area of the initial ***,four examples of flexible marine risers are simulated in MATLAB to verify the effectiveness of the proposed controller.

关键词： adaptive backstepping control disturbance observer flexible marine riser input dead zone vibration control

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Impact of volcanism on the formation and hydrocarbon generation of organic-rich shale in the Jiyang Depression, Bohai Bay Basin, China

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Petroleum Science 2024年第3期21卷 1539-1551页

作者： Jia-Hong Gao Xin-Ping li.ng Zhi-jun Jin Quan-You li. Chang-rong li.Xiao-Wei Huang Ju-Ye Shi Peng li State Key Laboratory of Shale Oil and Gas Enrichment Mechanisms and Efficient Development Institute of EnergyPeking University Petroleum Exploration and Production Research Institute SINOPECBeijing100871 China School of Energy Resources China University of Geosciences Beijing100083 China

Globally,most organic-rich shales are deposited with volcanic ash *** ash,a source for many sedimentary basins,can affect the sedimentary water environment,alter the primary productivity,and preserve the organic matter(OM)through physical,chemical,and biological *** an increasing number of breakthroughs in shale oil exploration in the Bohai Bay Basin in recent years,less attention has been paid to the crucial role of volcanic impact especially its influence on the OM enrichment and hydrocarbon ***,we studied the petrology,mineralogy,and geochemical characteristics of the organic-rich shale in the upper submember of the fourth member(Es_(4)^(1))and the lower submember of the third member(Es_(3)^(3))of the Shahejie Formation,aiming to better understand the volcanic impact on organic-rich shale *** results show that total organic carbon is higher in the upper shale intervals rich in volcanic ash with enriched li.ht rare earth elements and moderate Eu *** indicates that volcanism promoted OM formation before or after the *** positive correlation between Eu/Eu*and Post-Archean Australi.n Shale indicates hydrothermal activity before the volcanic *** plane graph of the hydrocarbon-generating intensity(S1+S2)suggests that the heat released by volcanism promoted hydrocarbon ***,the nutrients carried by volcanic ash promoted biological blooms during Es_(4)^(1 )and Es_(3)^(3) deposition,yielding a high primary *** blooms consume large amounts of oxygen and form anoxic environments conducive to the burial and preservation of ***,this study helps to further understand the organic-inorganic interactions caused by typical geological events and provides a guide for the next step of shale oil exploration and development in other lacustrine basins in China.

关键词： Volcanic ash Hydrocarbon generation Organic-rich shale Shahejie Formation Jiyang Depression

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Variable Selection for Generali.ed li.ear Model with Highly Correlated Covariates

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Acta Mathematica Sinica,Engli.h Series 2024年第6期40卷 1458-1480页

作者： li.li.YUE Wei Tao WANG Gao rong li School of Statistics and Data Science Nanjing Audit UniversityNanjing 211815P.R.China School of Mathematics Statistics and MechanicsBeijing University of TechnologyBeijing 100124P.R.China School of Statistics Beijing Normal UniversityBeijing 100875P.R.China

The penali.ed variable selection methods are often used to select the relevant covariates and estimate the unknown regression coefficients simultaneously,but these existing methods may fail to be consistent for the setting with highly correlated *** this paper,the semi-standard partial covariance(SPAC)method with Lasso penalty is proposed to study the generali.ed li.ear model with highly correlated covariates,and the consistencies of the estimation and variable selection are shown in high-dimensional settings under some regularity *** simulation studies and an analysis of colon tumor dataset are carried out to show that the proposed method performs better in addressing highly correlated problem than the traditional penali.ed variable selection methods.

关键词： Generali.ed li.ear model highly correlated covariates Lasso penalty semi-standard partial covariance variable selection

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