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Evaluation and Comparison of Medicine Students’ Knowledge about HPV

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Health 2023年第8期15卷 908-916页

作者： Clara Vitória Braz Lima de oliveira Carla Patrícia Alves Barbosa Alexandre Salomão de Barros oliveira Ana Paula Portela andrade Maria Eduarda Dantas Donald Arthur Carmo da Silva Iva Sampaio Bisneta Francisco Expedito Aguiar Sampaio Alexandre Salomão de Braz oliveira Elizabeth Bacha Tiradentes University Center (UNIT) Maceió Brazil Chesf Foundation for Assistance and Social Security (FACHESF) Aracaju Brazil Tiradentes University Center (UNIT) Aracaju Brazil department of Medicine University of Pernambuco (UPE) Recife Brazil

The Human Papillomavirus (HPV) is responsible for almost 99% of cervical cancers. Cervical cancer is a public health problem, being the fourth most common type of tumor among women worldwide and the third most common cancer among women in Brazil. It is known that cervical cancer is one of the most easily preventable forms of cancer, as there is a highly effective vaccine against HPV, however, morbidity and mortality rates related to human papillomavirus are still frightening, especially in less developed countries. Low vaccination adherence rates, especially the second dose, are probably a reflection of the lack of knowledge about this virus, its clinical repercussions, and the vaccine. A clinical trial was carried out in a higher education institution in Alagoas (Brazil), with students of the medical course to whom a validated questionnaire was applied on HPV in the virtual environment (google forms). Data collection was carried out throughout the month of May of the year 2023. It was shown that the knowledge of medical students about the human papillomavirus was less than what would be desired for future doctors. The alert for the acute need to assess health illiteracy is clear, especially regarding cancer that can be prevented by a highly effective vaccine.

关键词： Health Education HPV Health Literacy Cervical Cancer

Association between thrombomodulin and high mobility group box 1 in sepsis patients

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World Journal of Critical Care Medicine 2020年第4期9卷 63-73页

作者： Adriana Teixeira Rodrigues Julia Teixeira Rodrigues Carolina Teixeira Rodrigues Caroline Maria de oliveira Volpe Fabiana Rocha-Silva Jose Augusto Nogueira-Machado Luiz ronaldo Alberti department of Pediatrics School of MedicineFederal University of Minas GeraisBelo Horizonte 30130-100Minas GeraisBrazil Graduation Program in Medicine/Biomedicine-Santa Casa Hospital-Education and Research Belo Horizonte 30150-240Minas GeraisBrazil department of Pharmacy Federal University of Minas GeraisBelo Horizonte 31270-901Minas GeraisBrazil department of Internal Medicine Unimed HospitalBelo Horizonte 30150-340Minas GeraisBrazil department of Immunology Graduation Program in Medicine/Biomedicine-Santa Casa Hospital-Education and ResearchBelo Horizonte 30150-240Minas GeraisBrazil Clinical Laboratory Graduation Program in Medicine/Biomedicine-Santa Casa Hospital-Education and ResearchBelo Horizonte 30150-240Minas GeraisBrazil department of Surgery School of MedicineFederal University of Minas GeraisBelo Horizonte 30220-000Minas GeraisBrazil

BACKGROUND High mobility group box 1(HMGB1)has been studied as a molecule associated with severe outcomes in sepsis and thrombomodulin(TM)seems to decrease HMGB1 *** To investigate the role of the thrombomodulin/high mobility group box 1(T/H)ratio in patients with sepsis and their association with their clinic,testing the hypothesis that higher ratios are associated with better *** Twenty patients diagnosed with sepsis or septic shock,according to the 2016 criteria sepsis and septic shock(Sepsis-3),were *** were followed until they left the intensive care unit or until they achieved 28 d of hospitalization(D28).The following clinical outcomes were observed:Sequential Organ Failure Assessment(SOFA)score;Need for mechanical pulmonary ventilation;Presence of septic shock;Occurrence of sepsis-induced coagulopathy;Need for renal replacement therapy(RRT);and *** The results showed that patients with SOFA scores greater than or equal to 12 points had higher serum levels of TM:76.41±29.21 pg/mL vs 37.41±22.55 pg/mL among those whose SOFA scores were less than 12 points,P=*** T/H ratio was also higher in patients whose SOFA scores were greater than or equal to 12 points,P=*** T/H ratio was,on average,three times higher in patients in need of RRT(0.38±0.14 vs 0.11±0.09),Pdency for lower T/H ratio values.

关键词： High mobility group box 1 Sepsis Thrombomodulin Renal replacement therapy Mechanical ventilation Septic shock

Effects of Biochar on the Emissions of Greenhouse Gases from Sugarcane Residues Applied to Soils

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Agricultural Sciences 2017年第9期8卷 869-886页

作者： Thalita Fernanda Abbruzzini Mariana delgado oliveira Zenero Pedro Avelino Maia de andrade Fernando Dini Andreote Julio Campo Carlos Eduardo Pellegrino Cerri department of Soil Science “Luiz de Queiroz” College of Agriculture Piracicaba Brazil Institute of Ecology Universidad Nacional Autónoma de México México D.F. Mexico

The sugar and bioethanol industry generate large amounts of filter cake and vinasse, residues that are applied to sugarcane fields as conditioners and organic fertilizers. However, these may be significant sources of greenhouse gases emissions to the atmosphere. This study assessed the impact of sugarcane straw biochar on the emissions of CO2, CH4and N2O promoted by filter cake and vinasse applied to soil, and its effects on the chemical properties and bacterial communities of a Typic Hapludox and a Quartzipsamment. A laboratory incubation was conducted for 100 days with both soils under five treatments: vinasse and filter cake amendment (FV), plus biochar at 10 (FV + B10), 20 (FV + B20) and 50 (FV + B50) Mg·ha-1, and a control. Soil pH, available P and exchangeable base contents increased with biochar added to sandy soil. Mineral N decreased with biochar addition to both soils. The FV treatment increased CO2 emissions by 5-fold and 2.4-fold in sandy and clayey soils, respectively, compared to the control. Moreover, FV +B10 increased CO2 emissions by 4% and 6.4% in sandy and clayey soils, respectively, compared to FV. Cumulative N2O emissions in FV were 537% and 125% higher in sandy and clayey soils, respectively, compared to the control. Nevertheless, increasing biochar amendment rates reduced N2O emissions from 24% to 34% in sandy soil, and from 14% to 56% in clayey soil. CH4 emissions were negligible. The effects of filter, vinasse and biochar amendments on soil amelioration were closely related to its buffering capacity. Temporal changes on bacterial community structure were more pronounced in the sandy soil compared to clayey, and indicated that N2O emission mitigation in clayey soil was directly related to biotic mechanisms, while abiotic mechanisms caused by biochar played a more important role in mitigating N2O emissions in sandy soil.

关键词： Filter Cake Fingerprinting Nitrous Oxide Pyrolysis Carbon Soil Fertility Vinasse

Gasification of Municipal Solid Waste for Power Generation in Brazil, a Review of Available Technologies and Their Environmental Benefits

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Journal of Chemistry and Chemical Engineering 2016年第6期10卷 249-255页

作者： Diego Mauricio Yepes Maya Angie Lizeth Espinosa Sarmiento Cristina Aparecida Vilas Boas de Sales oliveira Electo Eduardo Silva Lora RubenildoVierira andrade Excellence Group in Thermal Power and Distributed Generation Institute of Mechanical Engineering Federal University ofltajuba Av. BPS 1303 Itajuba MG CEP 37500-903 Brazil Federal Center of Technological Education of Rio de Janeiro Celso Suckow da Fonseca CEFET-RJ Areal Street 522 Angra dosReis R J CEP 23953-030 Brazil

This article reviews the literature on thermochemical processing of municipal solid waste as the final disposal in Brazil, explores recent publications in the field of solid waste generated, its origin, characteristics and removal mechanisms currently employed, in the same way, available technologies for the thermochemical treatment of MSW with an emphasis on gasification and clean technology are evaluated, highlighting the current technical and reported in the literature in order to identify indicators of efficiency and flexibility of the technology. From the review it is concluded that gasification is a technically feasible option for the thermochemical conversion of municipal solid waste and subsequent power generation, besides being a technology that meets the applicable emission limits. Some of the main advantages of gasification of municipal solid waste are：（a） the sharp reduction in the waste mass （about 70-80%） and volume （approximately 80-90%）; （b） the drastic reduction in land use, 1：3000; （c） destruction of organic pollutants and other halogenated hydrocarbons; （d） concentration and immobilisation of inorganic contaminants so that they can be used effectively and safely removed; （e） use recyclables, such as ferrous metals, ferrous ash and slag materials; （f） reducing emissions of greenhouse gases by anaerobic decomposition of organic waste and （g） power generation.

关键词： MSW waste to energy gasification thermo-chemical conversion environmental advantage.

Prevalence of Low Levels of Vitamin D in Type 2 Diabetes at the City of Mangueirinha, Paraná, Southern Brazil

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Open Journal of Endocrine and Metabolic Diseases 2016年第1期6卷 8-12页

作者： Paulo Sérgio Chiamolera Cristiano Alvariza Amaral Monica Cristina de oliveira Russo Gilberto de oliveira Netto Ricardo Augusto Fernandes Ricardo Teles de andrade José Luiz Gonçalves Buscariolli denise Rosso Tenório Wanderley Rocha Alberto Krayyem Arbex Division of Endocrinology IPEMED Medical School Sao Paulo Brazil Visiting Scholar Harvard T. H. Chan School of Public Health Harvard University Boston USA

Background: Diabetes mellitus is a worldwide epidemic. In 2002 there were 173 million diabetic adults worldwide, and these numbers are expected to reach up to 300 million people by 2030. Meanwhile, vitamin D deficiency has its worldwide prevalence directly influenced by factors as solar radiation, skin color, latitude and seasons, cultural habits of populations such as clothing and food, and these factors are important to explain the different prevalences of vitamin D deficiency in the world. Methods: A prospective cross-sectional cohort study was conducted with patients in the outpatient clinic of the Health Unit of the city of Mangueirinha, Paraná, Southern Brazil. Fifty-four type 2 diabetic patients were evaluated (38 women and 16 men), aged 55.8 ± 12.6 years. The following variables were evaluated: age, ethnicity, presence of type 2 diabetes (DM2), hypertension, dyslipidemia, weight, BMI, WC, blood pressure, blood glucose, glycated hemoglobin, ionized calcium, PTH, 25-OH Vit, total cholesterol, HDL, LDL, urea, creatinine, uric acid and red cell/hematocrit. Results: mean BMI was 30.2 ± 4.4 kg/m2, indicating class 1 obesity in this population. Fasting glucose levels were approximately 169.8 ± 74.5 mg/dL. The 25-OH vitamin D values for this population were 23.4 ± 8.3 ng/mL, and 13% of them showed 25-OH vitamin D levels above 30 mg/dL. Fifty percent of those patients had vitamin D levels lower than 30 mg/dL, and 37% had less than 20 mg/dL. Conclusions: this study suggests that vitamin D is associated with low levels of vitamin D in type 2 diabetic patients. Supplementation of vitamin D should be considered in diabetic patients, when levels under 30 mg/mL are found.

关键词： 25 OH Vitamin D Type 2 Diabetes Mellitus Cardiovascular Risk

The structure of microbial populations in Nelore GIT reveals inter-dependency of methanogens in feces and rumen

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Journal of Animal Science and Biotechnology 2020年第2期11卷 577-586页

作者： Bruno G.N.andrade Flavia A.Bressani Rafael R.C.Cuadrat Polyana C.Tizioto Priscila S.N.de oliveira Gerson B.Mourão Luiz L.Coutinho James M.Reecy James E.Koltes Paul Walsh Alexandre Berndt Julio C.P.Palhares Luciana C.A.Regitano Embrapa Southeast Livestock São CarlosBrazil department of Molecular Epidemiology German Institute of Human Nutrition Potsdam-Rehbrücke(DIfE)NuthetalGermany NGS Genomic Solutions PiracicabaBrazil department of Animal Science University of São Paulo/ESALQPiracicabaBrazil department of Animal Science Iowa State UniversityAmesIAUSA NSilico Life Science DublinIreland

Background:The success of different species of ruminants in the colonization of a diverse range of environments is due to their ability to digest and absorb nutrients from cellulose,a complex polysaccharide found in leaves and *** rely on a complex and diverse microbial community,or microbiota,in a unique compartment known as the rumen to break down this *** in microbial populations of the rumen can affect the host’s development,health,and ***,accessing the rumen is stressful for the ***,the development and use of alternative sampling methods are needed if this technique is to be routinely used in cattle *** this end,we tested if the fecal microbiome could be used as a proxy for the rumen microbiome due to its *** investigated the taxonomic composition,diversity and inter-relations of two different GIT compartments,rumen and feces,of 26 Nelore(Bos indicus)bulls,using Next Generation Sequencing(NGS)metabarcoding of bacteria,archaea and ciliate ***:We identified 4265 Amplicon Sequence Variants(ASVs)from bacteria,571 from archaea,and 107 from protozoa,of which 143(96 bacteria and 47 archaea)were found common between both *** most prominent bacterial phyla identified were Bacteroidetes(41.48%)and Firmicutes(56.86%)in the ruminal and fecal microbiomes,respectively,with Prevotella and Ruminococcaceae UCG-005 the most relatively abundant genera identified in each *** most abundant archaeal phylum identified was Euryarchaeota,of which Methanobrevibacter gottschalkii,a methanogen,was the prevalent archaeal species identified in both *** were found exclusively identified in the rumen with Bozasella/Triplumaria being the most frequent genus ***-occurrence among ruminal and fecal ASVs reinforces the relationship of microorganisms within a biological ***,the co-occurrence of shared archaeal ASVs between microbiomes indicat

关键词： Archaea Bacteria Bos indicus Metabarcoding Methanobrevibacter Microbiome Microbiota

Variables Associated with Cirrhosis Diagnosis in Patients with Chronic Hepatitis C: A Case-Control Study

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Health 2015年第12期7卷 1634-1641页

作者： Gilmar Amorim de Sousa Iris do Céu Clara Costa Dyego Leandro Bezerra de Souza Fabia Barbosa de andrade Lívia Medeiros Soares Celani Ranna Santos Pessoa Marlon César de Souza Filho Daniel Fernandes Mello de oliveira Luana Lopes de Medeiros Lucila Samara Dantas de oliveira Maria Flávia Monteiro The Integrated department of Medicine Federal University of Rio Grande do Norte UFRN Natal Brazil The Post-Graduate Program in Collective Health of UFRN Natal Brazil Gastroenterology Program of the University Hospital Onofre Lopes/UFRN Natal Brazil The Medical School of UFRN Natal Brazil

The diagnosis of liver cirrhosis in patients with chronic hepatitis C has not always been easy, since the gold standard method is the liver biopsy, which is an invasive procedure with interobserver accuracy problems and there have been reports of complications including records of deaths due to hemoperitoneum. Cirrhosis changes the prognosis of the subject with hepatitis C and requires a different clinical management. This study aimed to identify clinical and laboratory variables associated with the diagnosis of cirrhosis in the ultrasonography of patients infected with hepatitis C. In a case-control study, we evaluated 70 cirrhotic patients with chronic hepatitis C compared to a control group of 70 non-cirrhotic people with positive HCV. The results showed, through logistic regression analysis, that the variables blood donor and professional athlete, adjusted for alcohol consumption, showed OR 0.24 and 0.18, with p values of 0.044 and 0.035, respectively. We conclude that the diagnosis of cirrhosis in patients with chronic hepatitis C remains challenging, but the patients with the condition of blood donor or professional athlete prove to be less likely to cirrhosis in ultrasonography in the initial consultation.

关键词： Cirrhosis Biomakers Fibrosis Hepatitis C Virus Clinical Diagnosis Biopsy Non-Invasive Methods Scores Ultrasonography

Growth and Photosynthetic Pigments of Cotton Cultivars Irrigated with Saline Water

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Agricultural Sciences 2019年第1期10卷 81-91页

作者： Elka Costa Santos Nascimento ronaldo do Nascimento André Alisson Rodrigues da Silva Carlos Vailan de Castro Bezerra Mateus Costa Batista Luana Lucas de Sá Almeida Veloso Márcia Cristina de Araújo Pereira Hallyson oliveira Federal University of Campina Grande Campina Grande Brazil

The cultivation of cotton is a relevant socioeconomic activity in the Brazilian agricultural scenario. In the Brazilian Northeast, however, production is limited by low rainfall, requiring water supplementation, a problem for the cotton cultivation practiced in the semi-arid region, due to the presence of saline ions in several water sources, from where the water is used for irrigation. It is necessary to identify cultivars that better tolerate saline stress in order to provide subsidies for their cultivation under such conditions. In this sense, the objective was to evaluate the tolerance of cotton cultivars to salinity. The experiment was conducted in a greenhouse, belonging to the Natural Resource Technology Center of the Federal University of Campina Grande, Campus I, Campina Grande, Brazil, in a completely randomized design in a 2 × 5 factorial scheme, with four replications, totaling 40 experimental units (BRS 368 RF and BRS SAFIRA) submitted to five saline levels (1.5, 3.0, 4.5, 6.0 and 7.5 dS·mˉ1). Irrigation with water saline of EC from 1.5 dS·mˉ1 affects adversely the growth of cotton cultivars, causing reductions in plant height, stem diameter, leaf area and number of leaves. Saline stress reduced the levels of the photosynthetic pigments of the cotton plants studied.

关键词： Gossypium hirsutum L. Salinity Chlorophyll

On Properties of Uniformly Strongly Fuzzy Ideals

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通讯和计算机（中英文版） 2016年第1期13卷 42-49页

作者： Flaulles B. Bergamaschi Alexsandra oliveira andrade Regivan H. N. Santiago department of Science and Technology Southwest Bahia State University Vitoria da Conquista Bahia 45.031-900 Brazil department of lnformatics and Applied Mathematics Federal University of Rio Grande do Norte Natal 59.078-900 Rio Grandedo Norte Brazil