检索结果-南通市图书馆

Let-7 in endometrial exosome/microvesicles induces a pluripotent paused state in mice

Let-7 in endometrial exosome/microvesicles induces a pluripo...

中国生理学会生殖科学专业委员会—中国动物学会生殖生物学分会第二次联合学术年会暨“生殖科学专业委员会第二次学术交流会”和“生殖生物学分会第十六次学术年会”

作者： Weimin Liu Ziru Niu Ranran Chen ronald tk pang Philip C.N.Chiu William S.B.Yeung ShenZhen institute University of HongKong Department of OG University of HongKong

Embryo dormancy(embryo diapause) is a reproductive strategy used by approximately 100 different mammals to avoid the risk of exposing their offsprings to unfavourable environmental conditions by delaying embryo *** molecular mechanism of embryonic diapause is not yet *** hypothesize that endometrial exosome/microvesicles(EV) regulates embryo *** detected miRNA profiles in EV between dormant and activated uterine fluid and found that the members of let-7 family were highly expressed in dormant uterine fluid ***,embryos have ability to take up endometrial exosomes/*** examine the roles of let-7 in embryo dormancy,we eletroporated let-7 a into embryos and found that embryos electroporated with let-7 can be alive even after the culture for up to Day 13.18.8%of embryos from let-7 g transgenic mice developed to term after culture for 6 days(ie Day 10).Microarray analysis showed that 47%gene expression were similar between let-7-treated and P4-induced dormant embryos compared to D4 or E2-activated embryos and most of genes were related to cell cycle and *** results showed that let-7 has an important role in the process of embryo dormancy in *** level of let-7 was elevated in Iin28 transgenic embryos which were transferred into wild-type delayed implantation model for 3 *** result suggests that the increased levels of let-7 in dormant embryo were mainly derived from outside *** exosomes/microvesicle of highly expressed let-7 prolonged the survival time of embryos in *** conclusion,our results demonstrated that let-7 of endometrial exosomes/microvesicles regulated embryo dormancy in mice.

关键词： exosome/microvesicle embryo diapause let-7

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Dielectric Relaxations in Ferroelectric Copolymer VDF(73)/TrFE(27)

引用

Journal of Materials Science & Technology 1995年第1期11卷 31-37页

作者： ZHANG, XY FURUKAWA, tk SCI UNIV TOKYO DEPT CHEMTOKYO 162JAPAN

The characteristics of molecular motion of ferroelectric copolymer VDF(73)/TrFE(27) have been investigated by means of dielectric relaxation. With the rise in crystallinity, the Curie point decreases and the dielectric constant increases in the region of ferroelectric-to-paraelectric phase transition. The frequency spectra of the copolymer below room temperature consist of low-frequency component ascribed to the micro-Brownian motions of molecular segments in the noncrystalline regions and high-frequency component associated with the local motions of small-scale segments. By using the fitting results with one or two Cole-Cole functions, and calculating with WLF equation acid Arrhenius formula,the glass transition temperature and the activation energy of local relaxation are obtained. the distribution of relaxation time in the molten and ferroelectric phases is located at a Same line, acid complies with Arrhenius rule, which suggests that the elementary motions are of same type for molecular motions provided by the high-temperature process and the low-temperature local mode process.

关键词： FLUORIDE-TRIFLUOROETHYLENE COPOLYMERS VINYLIDENE FLUORIDE CURIE TRANSITION CO-POLYMERS BEHAVIOR TETRAFLUOROETHYLENE DEPENDENCE

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Endoscopic hemoclip treatment for bleeding peptic ulcer

引用

World Journal of Gastroenterology 2000年第1期6卷 53-56页

作者： Lai YC Yang SS Wu CH Chen tk Division of Gastroenterology Cathay General HospitalTaipei Division of Gastroenterology Cathay General HospitalTaipei Medical FacultyChina Medical CollegeTaichungTaiwanChina

AIM To evaluate the efficacy of endoscopichemoclip in the treatment of bleeding *** Totally,40 patients with F1a andFib hemorrhagic activity of peptic ulcers wereenrolled in this uncontrolled prospective studyfor endoscopic hemoclip *** used anewly developed rotatable clip-device for theapplication of hemoclip(MD850)to *** was repeated if there wasany sign or suspicion of rebleeding,and re-clipping was performed if necessary *** Initial hemostatic rate by clippingwas 95%,and rebleeding rate was only 8%.Ultimate hemostatic rates were 87%,96%,and93% in the Fla and Flb subgroups,and totalcases,*** patients with shock onadmission,hemoclipping achieved ultimatehemostasis of 71% and 83% in F1a and F1bsubgroups,*** reached100% in patients without shock regardless ofhemorrhagic activity being F1a or *** number of clips used per case was 3.0(range 2-5).Spurting bleeders required moreclips on average than did oozing bleeders(3.4versus 2.8).We observed no obviouscomplications,no tissue injury,or impairmentof ulcer healing related to *** Endoscopic hemoclip placementis an effective and safe *** theimprovement of the clip and application device,the procedure has become easier and much *** hemoclipping deservesfurther study in the treatment of bleeding pepticulcers.

关键词： Subject headings endoscopic hemoclipping gastrointestinal hemorrhage/therapy peptic ulcer hemostasis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A Study on Impervious and Heat-Insulating Performance of Geomembrane Composites Within Breakwater

引用

China Ocean Engineering 1997年第2期12卷 213-224页

作者： Tao, tk Yu, L Yan, J Dong, ZY Hydraulic Engineering Department Nanjing Hydraulic Research Institute Nanjing 210029 China

This paper investigates the performance of geomembrane composites used as impervious and heat-insulating lining within a breakwater for a power station. The seepage field, distribution of stress-strain contour and seepage discharge of hot water which has been treated as the inner thermal source in the calculation of heat-insulation, have been given by three-dimensional calculation method coupling seepage with stress. The results indicate that the impervious and heat-insulation effect of geomembrane composites is significant.

关键词： breakwaters geomembrane composite impervious and heat-insulation

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

陆均松和青梅根系细菌群落多样性特征及其影响因素

引用

西北林学院学报 2024年第5期39卷 68-77页

作者：王欣庞通魏亚情许心诺李玉武兰国玉中国热带农业科学院橡胶研究所海南海口571101 海南儋州热带农业生态系统国家野外科学观测研究站海南儋州571737 华中农业大学园艺林学学院湖北武汉430070 青岛农业大学园林与林学院山东青岛266109

为进一步探究根系细菌群落结构与环境因子的关系,本研究基于不同生态位,以海南岛2种热带雨林典型植物陆均松和青梅的根系为研究对象,利用Illumina Miseq高通量测序技术对细菌群落结构、多样性及功能进行分析。结果表明:1)陆均松和青梅... 详细信息

为进一步探究根系细菌群落结构与环境因子的关系,本研究基于不同生态位,以海南岛2种热带雨林典型植物陆均松和青梅的根系为研究对象,利用Illumina Miseq高通量测序技术对细菌群落结构、多样性及功能进行分析。结果表明:1)陆均松和青梅根系细菌群落α多样性受到生态位的显著影响,根际和根表分别与根内细菌群落的α多样性指数存在极显著差异,并且α多样性沿根际-根表-根内生层的顺序呈下降趋势。2)根系细菌群落结构在不同生态位存在显著差异,生态位解释了根系细菌群落组成差异的14.7%,而植物种类解释了11.6%。在门水平上,相对丰度最高的前5个门依次为变形菌门、放线菌门、酸杆菌门、浮霉菌门和疣微菌门。热酸菌属、norank_f__Xanthobacteraceae、分枝杆菌属及Acidibacter、norank_f__norank_o__Elsterales是根系细菌群落的主要优势菌属。3)功能分析表明,细菌群落的一些功能群在根系不同生态位间存在显著差异,根表菌群富集大量功能群(化能异养、好氧化能异养等)。4)根系不同生态位细菌群落与不同的环境因子存在显著相关关系。驱动陆均松和青梅细菌结构差异的环境因子主要是温度和土壤pH。与树种相比,生态位对根系细菌群落结构有更强的影响,土壤pH、tk分别是影响根系细菌群落结构和多样性最重要的环境因子。研究结果为促进热带雨林濒危树种陆均松和青梅生长发育及其生态保护提供了科学依据。

关键词：陆均松青梅根系细菌群落生态位多样性

来源：

维普期刊数据库博看期刊

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

A rare medicinal fungus,Lignosus rhinocerus(Polyporales,Agaricomycetes),new to India

引用

Studies in Fungi 2021年第1期6卷 151-158页

作者： Vinjusha N Arun Kumar tk The Zamorin’s Guruvayurappan College(affiliated to the University of Calicut) Kerala 673014India

Lignosus rhinocerus is one of the most valuable medicinal fungi used throughout South East Asia,and South *** polypore is characterized by a stipitate basidiomata with orbicular pileus,and an underground sclerotium,a trimitic hyphal system bearing generative hyphae with clamp connections,and globose to subglobose ***,including the sclerotia of *** are used to treat various *** is rarely encountered in the wild and has a very restricted geographic *** of its rarity and importance,domestication and commercial cultivation of the fungus has been *** study of the polyporoid fungi in forests of Kerala State,India,some interesting specimens were *** taxonomic study of the collected specimens identified them as ***,with a distribution record new to *** account of the species is presented.

关键词： Polyporaceae sclerotia taxonomy therapeutic tiger milk mushroom

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neofomitella guangxiensis and Sebipora aquosa newly recorded white rot polypores from India

引用

Studies in Fungi 2021年第1期6卷 307-314页

作者： Vinjusha N Arun Kumar tk The Zamorin’s Guruvayurappan College KozhikodeKerala 673014India

As a part of the documentation of the polyporoid fungi of Kerala State,India,two interesting polypore specimens were *** and molecular characterization revealed the identity of two species as Neofomitella guangxiensis and Sebipora aquosa,which were reported as new records to *** present the taxonomy of the two species based on morphology and molecular phylogenetic data.

关键词： Gelatoporiaceae Polyporaceae Polyporales phylogeny wood decaying fungi

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Laser irradiation effects and its possible mechanisms of action on spermatozoa functions in domestic animals

引用

Asian pacific Journal of Reproduction 2017年第3期6卷 97-103页

作者： Lone SA Mohanty tk Kumaresan A Bhakat M Artificial Breeding Research Centre ICAR-National Dairy Research InstituteKarnal132001HaryanaIndia Livestock Research Centre ICAR-National Dairy Research InstituteKarnal132001HaryanaIndia

This article presents a review pertains the laser irradiation effects and its possible mechanisms of action on spermatozoa functions in domestic animals. To improve artificial insemination, laser is sensitive and cost effective technique, when compared to other conventional methods. Laser may have both positive and negative effects on spermatozoa functions. Since the effects of light are mediated by reactive oxygen species, and the levels of these reactive oxygen species following irradiating spermatozoa with laser may be responsible for determining the effects of laser on sperm. Dose of laser may be regarded as of great significance and this dosage of laser may be responsible for determining its effects on spermatozoa. Optimum dosage of laser for improving seminal attributes may vary among various species and this need to be standardized in each of them. The beneficial effects include improving sperm livability, acrosomal integrity, hypo-osmotic swelling response, mitochondrial function and computer-aided sperm analysis parameters. The increase in cytochrome c oxidase activity, ATP levels and mitochondrial membrane potential, in laser irradiated cells may be responsible for enhanced sperm quality parameters. Improving fertility with laser irradiated spermatozoa has been reported in few species like boar and need to be elaborated in other species. In conclusion laser may be regarded as an easy, cheap and time saving technology for improving artificial insemination;in addition, laser may have various potential applications in the field of reproductive biotechnology as well as in livestock farms and veterinary polyclinics.

关键词： Laser Irradiation Spermatozoa Function Mechanism

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

LANGMUIR－BLODGETT　FILM　OF　STRONG　LUMINESCENT　EUROPIUM　DIBENZOYLMETHANE　COMPLEXES

引用

Chinese Chemical Letters 1995年第10期6卷 903-906页

作者： Zhou, DJ Yao, GQ Huang, CH Bai, J Li, tk Beijing Univ State Key Lab Rare Earth Mat Chem & Applicat Beijing 100871 Peoples R China Acad Sinica Inst Photog Chem Beijing 100101 Peoples R China

Two strong fluorescent amphiphilic europium-dibenzoylmethane complexs Me3NC 16,H33.F(DBM)(A) and ***(DUM)4 (B) have heed synthesized and1 their Langmuir films have been formed at theair/water *** Langmuir film of of A can be easily transferred onto hydrophific substrates with transferratio around unity to huild up Langmuir-Blodgett(LB)*** LB films were characterized by UV-vis speetraand low-angle X-ray diffraction. Their fluorescence spectra and fluorescence lifetime have heen studied both insolution and highly ordered LB films.

关键词：

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Inhibitory activities of extracts of Rumex dentatus, Commelina benghalensis, Ajuga bracteosa, Ziziphus mauritiana as well as their compounds of gallic acid and emodin against dengue virus

引用

Asian Pacific Journal of Tropical Medicine 2018年第4期11卷 265-271页

作者： Riffat Batool Ejaz Aziz Tariq Mahmood Benny KH Tan Vincent tk Chow Department of Plant Sciences Faculty of Biological Sciences Quaid-i-Azam University Department of Pharmacology Yong Loo Lin School of Medicine National University of Singapore Department of Microbiology and Immunology Yong Loo Lin School of Medicine National University of Singapore

Objective: To investigate the inhibitory effects against dengue virus serotype 2(DENV-2) by five different fractions(extracted by methanol, ethanol, benzene, chloroform and n-hexane) of Rumex dentatus, Commelina benghalensis, Ajuga bracteosa and Ziziphus mauritiana, as well as their constituents(gallic acid, emodin, and isovanillic acid). Methods: All the samples were tested for cytotoxicity on baby hamster kidney cells by MTT assay and for anti-DENV-2 activity by plaque reduction neutralization assay using two DENV-2 doses(45 and 90 plaqueforming units or PFU). Results: All the samples except isovanillic acid exhibited significant prophylactic effects against DENV-2 infectivity(without cytotoxicity) when administered to cells before infection, but were not effective when given 6 h post-infection. The methanol extract of Rumex dentatus demonstrated the highest antiviral efficacy by inhibiting DENV-2 replication, with IC_(50) of 0.154 μg/mL and 0.234 μg/mL, when added before infection with 45 and 90 PFU of virus, respectively. Gallic acid also exhibited significant antiviral effects by prophylactic treatment prior to virus adsorption on cells, with IC_(50) of 0.191 μg/mL and 0.522 μg/mL at 45 and 90 PFU of DENV-2 infection, respectively. Conclusions: The highly potent activities of the extracts and constituent compounds of these plants against DENV-2 infectivity highlight their potential as targets for further research to identify novel antiviral agents against dengue.

关键词： Dengue virus Rumex dentatus Commelina benghalensis Ajuga bracteosa Ziziphus mauritiana Gallic acid

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：